Group items tagged

Great broad review of anti-cancer effects of low-dose metronomic chemotherapy

Case study of long-term survival in angiosarcoma with metronomic chemotherapy.

Low-dose, metronomic chemotherapy induces suppression of MDSCs in the TME in glioblastoma.

Animal study finds synergistic effects of hyperthermia, whole body, and metronomic chemotherapy after tumor removal to prevent metastasis.

Awesome article on how metronomic, low-dose chemotherapy reduces angiogenesis via decrease in HIF-1alpha and VEGF. Many other effects.

In many ways, it can be said that low-dose metronomic chemotherapy outperforms maximum tolerated chemotherapy.

Metronomic chemotherapy is an effective treatment for initial and maintenance.

Awesome read on the review of the effects of metronomic chemotherapy.

Great review of metronomic chemotherapy

Metronomic chemotherapy reduces MDSCs recruitment.

Only pdf available here. Start difference in the MTD to metronomic dosing of chemotherapy.

CPA administered on an intermittent, every 6-day metronomic schedule stimulates tumor recruitment of macrophages, natural killer (NK) cells, and dendritic cells with regression of large established tumors, as seen in several implanted glioma models; also of note, VEGF inhibition inhibited this effect.

Oral metronomic chemotherapy with celebrex shown to provide appx 50% stable NHL disease in refractory NHL.

Interesting case study using celecoxib, metronomic chemo (etoposide and cyclophosphamide) and Propranolol with positive results.

Overall QOL, but pain associated QOL was improved with metronomic very MTD.

Though not called metronomic chemotherapy, that is exactly what this was, reduced angiogenesis in chemo resistant tumors in mouse model. In fact, the higher dose intensity chemotherapy was less effective

Metronomic dosing out performs maximum tolerated chemotherapy in in vitro study.