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Ascorbate regulates haematopoietic stem cell function and leukaemogenesis : Nature : Na...
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www.nature.com/...nature23876.html
leukemia
cancer
vitamin c
IV vitamin c
Tet2
shared by
Nathan Goodyear
on 23 Oct 17
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Nathan Goodyear
on 23 Oct 17
Low vitamin C levels accelerate the initiation of leukemia. High dose vitamin C found to accumulate and promote Tet2 activity in haematopoietic stem cells, thereby decreasing initiation and progression of leukemia.
Low vitamin C levels accelerate the initiation of leukemia. High dose vitamin C found to accumulate and promote Tet2 activity in haematopoietic stem cells, thereby decreasing initiation and progression of leukemia.
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Whole‐genome analysis of TET dioxygenase function in regulatory T cells - PMC
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www.ncbi.nlm.nih.gov/...PMC8339674
vitamin C
cancer
TET
autoimmune disease
Ten-eleven translocation
shared by
Nathan Goodyear
on 19 Jul 22
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Vitamin C Facilitates Demethylation of the Foxp3 Enhancer in a Tet-Dependent Manner | T...
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www.jimmunol.org/...jimmunol.1502352.abstract
autoimmune
autoimmune disease
TET
vitamin C
Ten-eleven translocation
shared by
Nathan Goodyear
on 19 Jul 22
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Vitamin C protects against UV irradiation-induced apoptosis through reactivating silenc...
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pubmed.ncbi.nlm.nih.gov/25003799
vitamin C
TET
cancer
p21
p16
shared by
Nathan Goodyear
on 29 Aug 22
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High-Dose Vitamin C: Preclinical Evidence for Tailoring Treatment in Cancer Patients
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www.ncbi.nlm.nih.gov/...PMC8003833
high dose vitamin C
pharmacokinetics
High dose IV vitamin C
HIF-1alpha
high-dose IV vitamin C
HIF-1
vitamin C
ascorbic acid
TET2
Hypoxia-inducible Factor 1
cancer
IV vitamin C
hypoxia
vitamin C metabolism
shared by
Nathan Goodyear
on 02 Apr 21
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Nathan Goodyear
on 02 Apr 21
Another good, recent review article.
Another good, recent review article.
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Two Faces of Vitamin C-Antioxidative and Pro-Oxidative Agent - PMC
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www.ncbi.nlm.nih.gov/...PMC7285147
cancer
vitamin C
ascorbic acid
TET
shared by
Nathan Goodyear
on 31 May 22
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Regulation of the Epigenome by Vitamin C
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www.ncbi.nlm.nih.gov/...PMC4506708
cancer
epigenome
vitamin C
epigenetics
TET
ascorbic acid
shared by
Nathan Goodyear
on 08 Mar 22
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