Targeting tumor-infiltrating macrophages decreases tumor-initiating cells, relieves imm... - 0 views
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Nathan Goodyear on 16 Feb 21Chemotherapy increases TAMs in the primary tumors. These TAMs suppresses the anti-cancer cytotoxicity of T cells. The authors here describe both TAMs and TIMs. TAMs are the M1/M2 most often discussed. M2 TAMs increase Tumor Infiltrating Macrophages (TIMs) which increase local immunosuppression and chemotherapy resistance.