Regulatory Mechanisms for Adipose Tissue M1 and M2 Macrophages in Diet-Induced Obese Mice - 0 views
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Nathan Goodyear on 03 Jan 12M1 macrophages (and a high M1/M2 ratio) promote inflammation and insulin resistance in obese individuals; This is in contrast to M2 macrophages. Obese individuals will see a shift in M2 to M1. The exact mechanism is yet unknown. But M2 macrophages have been shown to resolve insulin resistance in this obese mice model