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Nathan Goodyear

Boswellia Serrata, A Potential Antiinflammatory Agent: An Overview - 0 views

www.ncbi.nlm.nih.gov/...PMC3309643

boswellia Frankincense inflammation NF-kappaB arthritis cancer osteoarthritis rheumatoid arthritis

shared by Nathan Goodyear on 07 Jun 16 - No Cached
  • Nathan Goodyear on 07 Jun 16
     
    review article of anti-inflammatory effects of Boswellia.  Boswellia inhibits 5-LOX and resultant leukotrienes.  3-actyl-11-keto-Beta-boswellic acid is the most potent inhibitor of 5-LOX.  As it relates to disease states and symptoms, Boswellia reduces pain in OA and RA.  Boswellia also shown to inhibit NF-kappa B: a potent nuclear transcription factor for inflammation.  In prostate cancer, Boswellia inhibits prostate tumor growth.
Nathan Goodyear

ScienceDirect.com - Free Radical Biology and Medicine - Anti-inflammatory effects of be... - 1 views

www.sciencedirect.com/...S0891584911011087

benfotiamine inflammation arachidonic acid LOX-5 COX-2

shared by Nathan Goodyear on 13 Jul 12 - No Cached
  • Nathan Goodyear on 13 Jul 12
     
    Benfotiamine's anti-inflammatory effect is through the inhibition of LOX-5 and COX-2.
Nathan Goodyear

ingentaconnect Boswellia serrata: An Overall Assessment of In Vitro, Preclinical... - 0 views

www.ingentaconnect.com/...art00001

11-keto-beta-boswellic acid acetyl-11-keto-beta-boswellic acid KBA AKBA inflammation Boswellia acid Frankincense

shared by Nathan Goodyear on 12 Jan 14 - No Cached
  • Nathan Goodyear on 12 Jan 14
     
    Study questions the 5-LOX inhibition as the mechanism of action of Boswellia due to its low absorption.  However, prostaglandin E production was inhibited.  Both have profound antiiflammatory effects and would benefit chronic inflammatory diseases.  
Nathan Goodyear

Omega-3 Fatty Acids and Inflammatory Processes - 0 views

www.ncbi.nlm.nih.gov/...PMC3257651

fats nutrition diet omega 3 inflammation NF-kappaB TNF-alpha omega-3 fish oil DHA EPA docosahexaenoic acid eicosapentaenoic acid

shared by Nathan Goodyear on 15 Sep 17 - No Cached
  • marine n-3 PUFAs have also been shown to alter the production of inflammatory proteins including chemokines, cytokines, growth factors and matrix proteases
  • Two transcription factors that are likely to play a role in inflammation are nuclear factor κ B (NFκB) and PPAR-γ
  • NFκB is the principal transcription factor involved in upregulation of inflammatory cytokine, adhesion molecule and cyclooxygenase-2 genes
  • ...3 more annotations...
  • PPAR-γ, is believed to act in an anti-inflammatory manner
  • PPAR-γ directly regulates inflammatory gene expression, it also interferes with the activation of NFκB creating an intriguing interaction between these two transcription factors
  • Both NFκB and PPAR-γ may be regulated by n-3 PUFAs.
  • Nathan Goodyear on 15 Sep 17
     
    great review of the anti-inflammatory effects of omega 3 DHA and EPA.  EPA inhibits COX and 5-LOX and their downstream prostaglandin and leukotrienes.  EPA/DHA inhibited endotoxin-stimulated IL-6, IL-8,TNF-alpha, and NFkappaB.
Nathan Goodyear

Modulation of arachidonic acid metabolism by curcumin and related β-diketone ... - 0 views

carcin.oxfordjournals.org/...1671.long

curcumin tumeric inflammation

shared by Nathan Goodyear on 13 Sep 13 - No Cached
  • Nathan Goodyear on 13 Sep 13
     
    Full text of curmin's inhibition of COX and LOX.
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