Skip to main content

Home/ Dr. Goodyear/ Group items tagged HIS

Rss Feed Group items tagged

pharmacybiz

HubRx key appointments to launch UK first automated pharmacy - 0 views

  •  
    Ahead of the launch of UK's first state-of-the-art automated hub for independent community pharmacists, HubRx has announced the appointment of Karl Wooldridge as operations director and Matthew Tollefson as chief financial officer. Karl brings more than 14 years of sector experience to his new role with HubRx. Having begun his career as an independent community pharmacist, Karl has gone on to hold key roles within pharmacy automation, including managing Phoenix Medical Supplies' offsite dispensing service. Commenting on his appointment, Karl said: "I'm delighted to have joined the team. The pandemic has further highlighted the important role pharmacists can play in keeping the nation healthy, not least in the delivery of the latest vaccination programme. The focus is now on pharmacists offering more clinical services, but to be able to achieve that the dispensing burden needs to be reduced. "HubRx is pioneering, our approach will transform community pharmacy. We're investing in cutting-edge technology to create an automated dispensing hub that will create capacity for pharmacists, allow them to grow and expand their skills." Matthew joins from Leeds-based corporate finance firm, Sentio Partners having also held positions with Mazars and Ernst & Young.
pharmacybiz

David Webb - England New Chief Pharmaceutical Officer - 0 views

  •  
    David Webb has been appointed as the new chief pharmaceutical officer (CPO) for England. He will take over from Dr Keith Ridge who steps down next month after serving the role for sixteen year. Webb is currently chief pharmacist and clinical director for pharmacy and medicines optimisation at Guy's and Thomas's NHS Foundation Trust, London. Sharing the news of his appointment on Twitter on Friday afternoon (January 7), he said he was "really delighted and honoured" to be named the CPO for NHS England and that he was as the appointed Chief Pharmaceutical officer for "looking forward to working with pharmacy leaders, colleagues & teams across all sectors from February." He also extended his gratitude to the outgoing CPO for his "outstanding contribution" who, in turn, congratulated Webb and said it was "an honour to be handing over to him". In the same message, Dr Ridge thanked "all the great people I've worked with over the last 16 years for your support, friendship, good humour, great ideas & challenge. I wish you all well for the future."
spineneuro

Charting New Horizons: Dr. Vipul Gupta's Vision for Interventional Radiology - 0 views

  •  
    Renowned for his excellence in neurological care, the Patient gives Dr. Vipul Gupta reviews and takes pride in delivering unparalleled neurosurgical care with the highest levels of technological and surgical advancements. Dr. Vipul Gupta interventional radiologist goal is to provide his patients from all over the world with the highest possible quality of life through his commitment to excellence.
wheelchairindia9

Handicapped Two Wheeler - 0 views

  •  
    Heavy duty mobility scooters are strong enough to accommodate almost any user. When compared with lighter units, mobility scooters models tend to feature bigger motors, wider bases, and larger tires. While a lighter model may be difficult to maneuver through rougher landscapes, mobility scooter is designed to tackle even the most challenging terrain.An excellent selection of scooters for sale. An extensive scooter accessories section, where find plenty of customization options to help ensure that the model select is a perfect fit. Side Wheels For Hero Pleasure: Side Wheel Attachment for Hero Pleasure or Side Wheels For Hero Pleasure or Three wheeler Hero Pleasure for handicapped is product, designed for use with bikes meant for the open road. Instead of shifting with a foot, a rider can drive easily their bike on road using his or her hand. This piece of equipment has been tested at well-known motorcycle tracks. This provides assembly and installation for all products at all facilities. Side Wheel Attachment For Hero Pleasure to fit the widest array of motorcycles and all-terrain vehicles possible. Side Wheel Attachment For Hero Pleasure Measurements: Frame : 38 mm 16 Gauge CR Pipe With Powder Coated Wheel Hub : Alloys Molded 2 Piece Tyre Size : 3.50 x 10 Inches 2 Piece Tube Size : 3.50 x 10 inches 2 Piece Shocks Up Heavy Duty 4 Piece ball baring 2 Piece pin bush 2 Piece mudguard chrome plated 2 Piece Disk with 4 Hole Wheel Type: Alloy Wheel Width: 40" to 48" inch Carrying Capacity: 100 -150 kg Side Wheels For Hero Pleasure Features: Independent Mobility Minimal Cost Heavy Duty International quality standards Comfort High level of performance Carrying Capacity: 100 -150 kg Sturdy design Provides excellent balance Provides excellent support High durability Side Wheels For CD Deluxe: Side Wheel Attachment for CD Deluxe or Side Wheels For CD Deluxe or Three wheeler CD Deluxe for handicapped is product, designed for u
Nathan Goodyear

Does Testosterone Lower Risk of Heart Attacks and Stroke? | Medical Research News and I... - 0 views

  •  
    This is a short interview of the author on a recent retrospective review that revealed no increase in cardiovascular events in men.  The author rightly points out his data, which is quite different than the previous JAMA and PLOSone publications which showed an increase in cardiovascular events.   However, the lead author points out the main problem with comparisons:  his study group was younger and healthier.  So, the comparison is apples to oranges.  Studies still point to increased risk of Testosterone therapy in men with pre-existing CVD.  This new study does not refute this point at all.   Another serious flaw here, is that only Testosterone was followed.  This logic is seriously flawed as I have previously documented.  The author points out the flaw in the levels in the JAMA study post treatment.  But he fails to account for the the lack of adequate pathway assessment i.e.aromatazation.  Also, no inflammatory cytokine evaluation was performed in that study.  Both of these should have been highlighted.    In contrast, a positive was the length of follow.
snfilms

There is no shortcut - easiest way is to be honest. - 0 views

  •  
    Yellowish cream denotes neutral and purified one. Almighty God has His own way of purifying His creations. সততার পথ সহজ, আপেক্ষিক দৃষ্টিতে পাপের রাস্তা যতই লোভনীয় হোক না কেন । Be honest, be purified. Happy birthday
finchloe121

Insomnia What You Know and What You Don't! - 0 views

  •  
    Most of you would know that insomnia is a sleep problem, and it causes difficulty in falling asleep and staying asleep for a reasonable amount of time. It also affects sleep quality, resulting in daytime inactivity. Most of the time, insomnia can become long-term. This long-term insomnia is called chronic insomnia. This type of insomnia is diagnosed when the patient has trouble sleeping, at least 3 to 4 days a week for at least one month. Acute insomnia or short-term insomnia is the most common type of insomnia that most people have today. As the name suggests, it is a short-term illness and lasts only for a few days or at most three to four weeks. Consult your doctor, get a proper check-up, explain all the problems including your sleep schedule. Initially, severe insomnia symptoms may not require adequate treatment. If a person feels tired and cannot perform his physical activities during the day, he should buy sleeping pills for a short time as per the prescription of his doctor or physician. If your symptoms are not under control, use cheap Temazepam 10 mg tablets available online. You can buy these insomnia pills online from Pharma Health Online.
umar111

A*Men Mugler Perfume - PlazzaPK - 0 views

  •  
    A*Men Mugler Paris Perfume A*Men Mugler Perfume the first male fragrance created by MUGLER, materializes the contemporary hero, a man who imposes himself by his inner strength, and his desire to win.
spineneuro

Dr. Sandeep Vaishya: A Closer Look at His Surgical Skill through Reviews - 0 views

  •  
    The patient takes Dr. Sandeep Vaishya reviews, who is renowned for his expertise in minimally invasive spine surgery. With a comprehensive array of specialized skills and superior outcomes in India, Dr Sandeep Vaishya neurosurgeon addresses a wide range of conditions, from neck and back pain to brain/spinal tumors and injuries.
Smile Reef

Pediatric Dentist Teaching Children Oral Health - 0 views

  •  
    Dr. Jensen and his staff at Smile Reef Pediatric Dentistry in Las Vegas had a great time visiting over 600 students at Goolsby Elementary School! Dr. Jensen led the students through a hands-on demonstration of proper hygiene and dental health.
Smile Reef

Smile Reef Dental Staff Teaching Children During Dental Awareness Month - 0 views

  •  
    Dr. Jensen and his staff enjoyed teaching these elementary kids during dental health awareness month.
Smile Reef

Pediatric Dentist in Las Vegas Teaching Kids To Brush And Floss - 0 views

  •  
    Dr. Jensen and his staff at Smile Reef Pediatric Dentistry in Las Vegas had a great time visiting over 600 students at Goolsby Elementary School! Dr. Jensen led the students through a hands-on demonstration of proper hygiene and dental health.
Nathan Goodyear

Metabolic management of brain cancer - 0 views

  • Glutamine is a major metabolic fuel for both brain tumor cells and tumor-associated macrophages (TAMs)
  • the malignant phenotype of brain tumor cells that survive radiotherapy is often greater than that of the cells from the original tumor.
  • Conventional chemotherapy has faired little better than radiation therapy for the long-term management of malignant brain cancer
  • ...37 more annotations...
  • most conventional radiation and brain cancer chemotherapies can enhance glioma energy metabolism and invasive properties, which would contribute to tumor recurrence and reduced patient survival [34].
  • We contend that all cancer regardless of tissue or cellular origin is a disease of abnormal energy metabolism
  • complex disease phenotypes can be managed through self-organizing networks that display system wide dynamics involving oxidative and non-oxidative (substrate level) phosphorylation
  • As long as brain tumors are provided a physiological environment conducive for their energy needs they will survive; when this environment is restricted or abruptly changed they will either grow slower, growth arrest, or perish [8] and [19]
  • New information also suggests that ketones are toxic to some human tumor cells and that ketones and ketogenic diets might restrict availability of glutamine to tumor cells [68], [69] and [70].
  • The success in dealing with environmental stress and disease is therefore dependent on the integrated action of all cells in the organism
  • Tumor cells survive in hypoxic environments not because they have inherited genes making them more fit or adaptable than normal cells, but because they have damaged mitochondria and have thus acquired the ability to derive energy largely through substrate level phosphorylation
  • Cancer cells survive and multiply only in physiological environments that provide fuels (mostly glucose and glutamine) subserving their requirement for substrate level phosphorylation
  • Integrity of the inner mitochondrial membrane is necessary for ketone body metabolism since β-hydroxybutyrate dehydrogenase, which catalyzes the first step in the metabolism of β-OHB to acetoacetate, interacts with cardiolipin and other phospholipids in the inner membrane
  • the mitochondria of many gliomas and most tumors for that matter are dysfunctional
  • Cardiolipin is essential for efficient oxidative energy production and mitochondrial function
  • Any genetic or environmental alteration in the content or composition of cardiolipin will compromise energy production through oxidative phosphorylation
  • The Crabtree effect involves the inhibition of respiration by high levels of glucose
  • the Warburg effect involves elevated glycolysis from impaired oxidative phosphorylation
  • the Crabtree effect can be reversible, the Warburg effect is largely irreversible because its origin is with permanently damaged mitochondria
  • The continued production of lactic acid in the presence of oxygen is the metabolic hallmark of most cancers and is referred to as aerobic glycolysis or the Warburg effect
  • We recently described how the retrograde signaling system could induce changes in oncogenes and tumor suppressor genes to facilitate tumor cell survival following mitochondrial damage [48].
  • In addition to glycolysis, glutamine can also increase ATP production under hypoxic conditions through substrate level phosphorylation in the TCA cycle after its metabolism to α-ketoglutarate
  • mitochondrial lipid abnormalities, which alter electron transport activities, can account in large part for the Warburg effect
  • targeting both glucose and glutamine metabolism could be effective for managing most cancers including brain cancer
  • The bulk of experimental evidence indicates that mitochondria are dysfunctional in tumors and incapable of generating sufficient ATP through oxidative phosphorylation
  • Cardiolipin defects in tumor cells are also associated with reduced activities of several enzymes of the mitochondrial electron transport chain making it unlikely that tumor cells with cardiolipin abnormalities can generate adequate energy through oxidative phosphorylation
  • The Crabtree effect involves the inhibition of respiration by high levels of glucose
  • Warburg effect involves elevated glycolysis from impaired oxidative phosphorylation
  • TCA cycle substrate level phosphorylation could therefore become another source of ATP production in tumor cells with impairments in oxidative phosphorylation
  • Caloric restriction, which lowers glucose and elevates ketone bodies [63] and [64], improves mitochondrial respiratory function and glutathione redox state in normal cells
  • DR naturally inhibits glycolysis and tumor growth by lowering circulating glucose levels, while at the same time, enhancing the health and vitality of normal cells and tissues through ketone body metabolism
  • DR is anti-angiogenic
  • DR also reduces angiogenesis in prostate and breast cancer
  • We suggest that apoptosis resistance arises largely from enhanced substrate level phosphorylation of tumor cells and to the genes associated with elevated glycolysis and glutaminolysis, e.g., c-Myc, Hif-1a, etc, which inhibit apoptosis
  • Modern medicine has not looked favorably on diet therapies for managing complex diseases especially when well-established procedures for acceptable clinical practice are available, regardless of how ineffective these procedures might be in managing the disease
  • More than 60 years of clinical research indicates that such approaches are largely ineffective in extending survival or improving quality of life
  • The process is rooted in the well-established scientific principle that tumor cells are largely dependent on substrate level phosphorylation for their survival and growth
  • Glucose and glutamine drive substrate level phosphorylation
  • targeting the glycolytically active tumor cells that produce pro-cachexia molecules, restricted diet therapies can potentially reduce tumor cachexia
  • It is important to recognize, however, that “more is not better” with respect to the ketogenic diet
  • Blood glucose ranges between 3.0 and 3.5 mM (55–65 mg/dl) and β-OHB ranges between 4 and 7 mM should be effective for tumor management
  •  
    Dr Seyfriend presents his metabolic approach to the treatment of brain cancer.
Smile Reef

Pediatric Dentist Teaching Children Oral Health - 0 views

  •  
    Dr. Jensen and his staff at Smile Reef Pediatric Dentistry in Las Vegas had a great time visiting over 600 students at Goolsby Elementary School! Dr. Jensen led the students through a hands-on demonstration of proper hygiene and dental health.
Nathan Goodyear

Erratum to: DNA methylation age of human tissues and cell types | Genome Biology | Full... - 0 views

  •  
    correction of his Hovarth's prior publication in 2013.
arunaraayala

Berlin Sheds Tear for Post-War Order as Trump Era Looms | LocalityNews - 0 views

  •  
    US President Obama & German Chancellor Angela Merkel may have made a tough start, but his imminent departure sparked a wave of nostalgia and trepidation in Berlin.
jiyaroy11

The Deadly Look of Akshay Kumar in Rajnikanth New Movie - 0 views

  •  
    CRB Tech reviews reveals the crow look of Akshay Kumar in Enthiran 2. Akshay Kumar never shies away to shock us. However much did we expect he'll concocting such a fatal treat in his next.
Nathan Goodyear

Concomitant Dietary Supplement and Prescription Medication Use Is Prevalent among US Ad... - 0 views

  •  
    Study worries over the risks of supplements and prescription drugs.  The author should worry more over the lack of knowledge by physicians of the health benefits of supplements.  Instead of focusing on the prescriptions themselves, how about focusing on the supplements to reduce the need for the prescriptions.  This authors focus is all wrong.   Obviously, the patient needs to be forthcoming with his/her physician about all supplements that they are on.  
Meredith Blige

Proven Very Effective Anti-Snoring Products - 1 views

My husband kept asking me the question "how can I stop snoring" because I always told him that I cannot get enough sleep due to his loud snoring. He was worried that I might get sick, so we searche...

how can I stop snoring

started by Meredith Blige on 25 Oct 11 no follow-up yet
ajaykumarind091

Coleus Forskolii Manufacturers -commonly known as Indian Coleus - 0 views

  •  
    Star Hi Herbs Pvt Ltd. With 10 years dynamic experience have developed Coleus Forskolii Manufacturers inconsistent quality products as per gmp and cgmp Guidelines. Our company is a product-development and marketing company. We are manufacturers of standardized herbal extracts of natural products, neutraceuticals, phytochemicals, oleoresins cosmetics etc.
1 - 20 of 72 Next › Last »
Showing 20 items per page