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Nathan Goodyear

A Natural Combination Extract of Viscum album L. Containing Both Triterpene Acids and L... - 0 views

www.ncbi.nlm.nih.gov/...PMC4526680

AML acute myeloid leukemia Mistletoe

shared by Nathan Goodyear on 05 Jul 22 - No Cached
  • Nathan Goodyear on 05 Jul 22
     
    Viscum album L. (Loranthaceace)
Nathan Goodyear

Safety of Combined Treatment With Monoclonal Antibodies and Viscum album L Preparations - 0 views

www.ncbi.nlm.nih.gov/...PMC5950938

VAE mistletoe cancer monoclonal antibodies mAB IL-12 NK cells

shared by Nathan Goodyear on 06 Jun 18 - No Cached
  • Among the most encouraging mAb is trastuzumab, which targets the human epidermal growth factor receptor 2 and is indicated in the treatment of breast cancer
  • bevacizumab, which inhibits vascular endothelial growth factor and is indicated in the treatment of a range of diseases, including colorectal, lung, and ovarian cancer3; and cetuximab, which blocks the epidermal growth factor receptor and is indicated in the treatment of colorectal and lung cancer
  • Viscum album L (VA or European mistletoe) preparations are widely used as additive cancer therapy in Europe, especially in German-speaking countries, and have been associated with a reduction in chemotherapy-related adverse drug reactions and increased HRQL
  • ...6 more annotations...
  • leading to enhancement of interleukin-12 secretion and natural killer cell function
  • Helixor VA preparations
  • A multivariable GEE model indicated that the odds for patients experiencing an AE following mAb therapy were nearly 5 times higher compared with that for mAb plus VA
  • VA preparations (Iscador Ltd) did not inhibit chemotherapy-induced cytostasis or cytotoxicity and showed an additive inhibitory effect at higher concentrations of VA.
  • previous in vitro investigations have shown that VA preparations have either no or minor effects on a range of CYPs, suggesting that VA-drug interactions based on drug metabolism are unlikely
  • mAb do not undergo hepatic metabolism but undergo proteolytic catabolism throughout the body
  • Nathan Goodyear on 06 Jun 18
     
    VAE therapy found to reduce adverse events in those receiving monoclonal Ab therapy.
Nathan Goodyear

Intratumoral injections of viscum album mistletoe in malignant left inguinal large sarcoma - 0 views

www.longdom.org/...uinal-large-sarcoma-34385.html

sarcoma cancer mistletoe

shared by Nathan Goodyear on 27 May 20 - No Cached
  • Nathan Goodyear on 27 May 20
     
    intratumoral + IV mistletoe found to be helpful in reduction in cancer cell proliferation.
Nathan Goodyear

Use and Safety of Intratumoral Application of European Mistletoe (Viscum albu... - 0 views

journals.sagepub.com/...1534735414563977

mistletoe cancer intra-tumoral injection

shared by Nathan Goodyear on 21 Apr 20 - No Cached
  • Nathan Goodyear on 21 Apr 20
     
    To be read
Nathan Goodyear

Intratumoral Mistletoe (Viscum album L) Therapy in Patients With Unresectable... - 0 views

journals.sagepub.com/...1534735413513637

pancreatic cancer intra-tumoral injection mistletoe

shared by Nathan Goodyear on 21 Apr 20 - No Cached
  • Nathan Goodyear on 21 Apr 20
     
    To be read
Nathan Goodyear

Intralesional and subcutaneous application of Viscum album L... : Medicine - 0 views

journals.lww.com/...articleviewer.aspx

intra-tumoral injection cancer Mistletoe cervical cancer

shared by Nathan Goodyear on 21 Apr 20 - No Cached
  • Nathan Goodyear on 21 Apr 20
     
    To be read
Nathan Goodyear

Reducing malignant ascites accumulation by repeated intraperitoneal administrations of ... - 0 views

www.researchgate.net/...ions_of_a_Viscum_album_extract

Intra-peritoneal ascites cancer mistletoe

shared by Nathan Goodyear on 07 Apr 21 - No Cached
  • Nathan Goodyear on 07 Apr 21
     
    Intra-peritoneal v. Mali used to treat malignant ascites.
Nathan Goodyear

Mistletoe (Viscum album) extract targets Axl to suppress cell proliferation and overcom... - 0 views

www.sciencedirect.com/...S0944711317301356

cancer mistletoe

shared by Nathan Goodyear on 01 Jun 19 - No Cached
  • Nathan Goodyear on 01 Jun 19
     
    Mistletoe found to inhibit cancer cell proliferation and reduce chemo-resistance.
Nathan Goodyear

Viscum album neutralizes tumor-induced immunosuppression in a human in vitro cell model - 0 views

journals.plos.org/...article

cancer immunomodulation immunotherapy mistletoe

shared by Nathan Goodyear on 27 May 20 - No Cached
  • Nathan Goodyear on 27 May 20
     
    mistletoe found to reduce immunosuppression, most likely in TME, in vitro study.
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