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Nathan Goodyear

Anti-inflammatory action of progesterone on carrageenin-induced inflammation in rats - 0 views

www.jstage.jst.go.jp/..._pdf

progesterone hormone hormones anti-inflammatory inflammation vascular permeability BHRT

shared by Nathan Goodyear on 07 Jun 12 - No Cached
  • Nathan Goodyear on 07 Jun 12
     
    progesterone shown to prevent vascular permeability and granulation in early inflammatory responses.
Nathan Goodyear

Photodynamic therapy: a means to enhanced drug delivery to tumors - PubMed - 0 views

pubmed.ncbi.nlm.nih.gov/14678965

photodynamic therapy PTD cancer chemotherapy

shared by Nathan Goodyear on 02 Nov 22 - No Cached
  • Nathan Goodyear on 02 Nov 22
     
    Increases tumor uptake via effect on vascular permeability.
Nathan Goodyear

Lipopolysaccharide‐induced metastatic growth is associated with increased ang... - 0 views

onlinelibrary.wiley.com/...ijc.10632

VEGF cancer LPS

shared by Nathan Goodyear on 16 Aug 19 - No Cached
  • Nathan Goodyear on 16 Aug 19
     
    LPS increases angiogenesis and metastasis in cancer tumor model.
Nathan Goodyear

Neoadjuvant chemotherapy induces breast cancer metastasis through a TMEM-mediated mecha... - 0 views

stm.sciencemag.org/...eaan0026

chemotherapy TMEM tumor microenvironment of metastasis metastasis cancer

shared by Nathan Goodyear on 11 Jul 17 - No Cached
  • We found about a twofold increase in circulating tumor cells (CTCs) (P < 0.05) after paclitaxel treatment in all experimental models examined
  • We found an increase in both the metastatic incidence (at least one micrometastatic focus of more than five tumor cells) (Fig. 3I) and the number of cancer cell micrometastases in the lungs of paclitaxel-treated mice
  • in early-stage breast cancers, chemotherapy increases vascular permeability at TMEM sites, which is accompanied by increased cancer cell dissemination.
  • ...1 more annotation...
  • significant ~1.3-fold (P = 0.027) increase in the number of CTCs
  • Nathan Goodyear on 11 Jul 17
     
    New study suggests chemotherapy may increase metastasis  via increase in TMEM.  I wonder if this increases recurrence as well.  Could the very corner stone of Cancer therapy actually increase metastatic risk potential?
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