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Casetext is a free legal research tool that lets you annotate the law.
With Casetext you can: search using keywords or citations, read the full text of over one million federal and Delaware cases, and learn insights from the annotations of practicing attorneys, professors, and other experts.
Fats in foods like potato chips and french fries make them nearly irresistible because they trigger natural marijuana-like chemicals in the body called endocannabinoids, researchers at the University of California, Irvine, have found.
The researchers discovered that when rats tasted something fatty, cells in their upper gut started producing endocannabinoids, while sugars and proteins did not have this effect.
How fats create, like, a buzz
It starts on the tongue, where fats in food generate a signal that travels first to your brain, and then through a nerve bundle called the vagus to your intestines. There, the signal stimulates the production of endocannabinoids, which initiates a surge in cell signaling that prompts you to totally pig out - probably by initiating the release of digestive chemicals linked to hunger and satiety that compel us to eat more. And that leads to obesity, diabetes and cancer, the researchers said.
But they suggest it might be possible to curb this process by obstructing endocannabinoid activity: for example, by using drugs that "clog" cannabinoid receptors. The trick: bypassing the brain to avoid creating anxiety and depression (which happens when endocannabinoid signaling is blocked in the brain). I'm guessing McDonald's won't be adding that drug to their fries.
Ref.: Daniele Piomelli, et al., An endocannabinoid signal in the gut controls dietary fat intake, PNAS, 2011; in press
This site lists free online computer science, engineering and programming books, textbooks and lecture notes, all of which are legally and freely available over the Internet.
handbook introduces you to the legal, social and technical aspects of open data. It can be used by anyone but is especially useful for those working with government data. It discusses the why, what and how of open data - why to go open, what open is, and the how to do open.
The British National Bibliography (BNB) lists the books and new journal titles published or distributed in the United Kingdom and Ireland since 1950. It also lists forthcoming book titles and hand-held electronic publications e.g. CD-ROMs, deposited with the Legal Deposit Office since 2003.
'Open knowledge' is any content, information or data that people are free to use, re-use and redistribute - without any legal, technological or social restriction. We detail exactly what openness entails in the Open Knowledge Definition.
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