Group items tagged

"14.06.2013 - Biologie, Geowissenschaften William Orsi (Woods Hole Oceanographic Institution, Woods Hole) et al., Nature, doi: 10.1038/nature12230 Aktives Leben in der Tiefe RNA-Analyse liefert ersten umfassenden Überblick über Aktivität, Ernährung und Bewegungsformen in der tiefen Biosphäre"

OpenWetWare is an effort to promote the sharing of information, know-how, and wisdom among researchers and groups who are working in biology & biological engineering. If you would like edit access, would be interested in helping out, or want your lab website hosted on OpenWetWare, please join us. OpenWetWare is managed by the BioBricks Foundation."

"I visit a lot of molecular biology labs, and most of them look pretty much identical: lab benches, microscopes, computers, messy break rooms, big filing cabinets crammed into every free corner. When you look closely, though, every lab has its own flavor, its own culture. This is the first post of what I hope will be a fun, photo-heavy series on the culture of different labs. Florian Engert's lab at Harvard is large, colorful, and messy."

@Spatzlhirn "Afrikanische Mistkäfer (Scarabaeus satyrus) orientieren sich nicht nur an der Sonne, dem Mond und der Polarisation des Tageslichtes. Anders als viele andere Insekten nutzen sie für die Navigation offenbar auch die Sterne. Genau genommen ist es die Milchstraße - jener Teil unserer Galaxie, der als helles Band am nächtlichen Himmel zu sehen ist - um in mondlosen Nächten ihren Weg zu finden. Das berichten Marie Dacke von der Universität Lund und ihre Kollegen aus Schweden und Südafrika im Fachjournal Current Biology (online)."

"A new bioprinter developed at a hackerspace can print living cells for less than the cost of an iPod touch. 3-D bioprinters have the potential to change the way medical research is conducted, even print living tissue and replacement organs, but they are expensive and highly specialized. They literally build living structures, like blood vessels or skin tissue, cell by cell, revolutionizing biomedical engineering. Unfortunately, they're expensive, rare, and require a Ph.D. (or two) to operate successfully. Frustrated by their cost and exclusivity, a group of makers at the DIYbio hackerspace BioCurious are developing a system open to anyone with a soldering iron and a serious passion for cell biology."

"Die Ergebnisse zeigen, dass das angeborene Fluchtverhalten auf Kohlendioxid in Fruchtfliegen je nach ihrem Sättigungszustand von zwei parallelen neuronalen Schaltkreisen gesteuert wird. „Ist die Fliege hungrig, verlässt sie sich nicht mehr auf die "direkte Leitung", sondern benutzt Hirnzentren, mit denen sie interne und äußere Signale abwägen und eine ausgewogene Entscheidung treffen kann", erklärt Grunwald-Kadow und fügt hinzu: „Es ist faszinierend, in welchem Ausmaß der Stoffwechsel und Hunger die verarbeitenden Prozesse im Gehirn beeinflussen." ***** Lasse B. Bräcker, K.P. Siju, Nelia Varela, Yoshinori Aso, Mo Zhang, Irina Hein, Maria Luisa Vasconcelos, Ilona C. Grunwald Kadow Essential role of the mushroom body in context dependent CO2 avoidance in Drosophila Current Biology, 13 June 2013 Max-Planck-Institut für Neurobiologie"

"Genspace betreibt seit 2010 in Brooklyn ein Labor, das allen Bürgern offen steht, die sich für Molekularbiologie und moderne Biotechnologie interessieren, oder vielleicht auch nur Lust haben, einmal mit Pilzkulturen und Petrischalen zu hantieren. Besondere Erfahrungen und Vorkenntnisse muss niemand mitbringen, nur die Gebühr für den jeweiligen Kurs. Da können dann zum Beispiel Schüler in der Freizeit Mikroorganismen in Petrischalen züchten, oder der Rentner von nebenan lernt im Crashkurs, Genproben zu analysieren. „Es gibt nichts Besseres, als selbst etwas auszuprobieren, wenn man jemand für Wissenschaft begeistern will"

Come work with us Interested in working with researchers from different disciplines within the Harvard, MIT and Broad community and an unique opportunity to participate in world-class research to make an impact on human health? Come work with us! We are looking for a computational biologists to handle data from a wide variety of experimental methods, focusing on next-gen sequencing technologies. Keep Reading...  SCDE is live The Stem Cell Discovery Engine (SCDE) is an integrated platform that allows users to consistently describe, share and compare cancer and tissue stem cell data. It is made up of an online database of curated experiments coupled to a customized instance of the Galaxy analysis engine with tools for gene list manipulation and molecular profile comparisons. The SCDE currently contains more than 50 stem cell-related experiments. Each has been manually curated and encoded using the ISA-Tab standard to ensure the quality of the data and its annotation. Keep Reading...  The Center for Health Bioinformatics at the Harvard School of Public Health provides consults to researchers for the management, integration and contextual analysis of biological high-throughput data. We are a member of the Center for Stem Cell Bioinformatics, the Environmental Statistics and Bioinformatics Core at the Harvard NIEHS Center for Environmental Health and the Genetics & Bioinformatics Consulting group for Harvard Catalyst and work closely with our colleagues in the Department of Biostatistics and the Program in Quantitative Genomics to act as a single point of contact for computational biology,

William Gunn The Top 10 papers in Biological Sciences by Mendeley readership. With the Mendeley for Life Scientists webinar coming up on Thursday, I thought I would take a look at the readership stats for Biological Sciences. Biological Sciences has long been our biggest discipline, and having done my doctoral work in the Life Sciences, I knew this would be interesting. Overall, researchers in bioinformatics contributed most strongly to the most read papers, along with the older disciplines of micro- and molecular biology. Regardless of discipline, however, it's clear that the days of toiling away in isolation to thoroughly study one gene are over. Today, it's all about huge consortia and massive data. Here's what I found

"However, anthropological datasets show enormous complexity in how and why men and women behave the ways that they do [vi]. Studies in human biology and anthropology regularly demonstrate a dynamic flexibility and complex biocultural context for all human behavior, and this is especially true for gender.... No matter how much some want it to be true, it is just not that simple; there are no clear cut and easy answers to why we do what we do, and why men and women sometimes have problems getting along. To ignore the enormous wealth of data on how men and women are similar AND different and to try to tackle this enormously complex reality via one-dimensional approaches is just poor science."

"I am going to try and experiment within an experiment today. I cloned a couple genes from yeast and have been spending months now trying to get them into several vectors for my combinatorial overexpression project. However, as it goes with wet messy biology, this seemingly simple process has been fighting me tooth and nail. I have retrieved one good clone out of 56 minipreps (plasmid construct isolation) and tried several ligations. So I have tripled down this week. In the picture here, I have 32 tubes, each with 5 individual E. coli colonies. That is a grand total of 160 isolates. 1.5 mL of cells have been transferred from overnight cultures and I am about to spin, lyse, and retrieve."

a great and excessive information portal

Susanna Larsson: Kaffeetrinkerinnen haben ein geringeres Risiko für Hirninfarkte http://www.wissenschaft.de/wissenschaft/news/313141.html (Jingmei Li, Karolinska Institutet, et al.: Breast Cancer Research, Bd. 13, Artikel R49) Yvonne T. van der Schouw (UMC Utrecht) et al.: Arteriosclerosis, Thrombosis, and Vascular Biology: Journal of the American Heart Association, doi: 10.1161/ATVBAHA.109.201939 http://www.wissenschaft.de/wissenschaft/news/311350.html Helena Jernström: Kaffee senkt das Brustkrebsrisiko http://www.wissenschaft.de/wissenschaft/gutzuwissen/291553.html

Open Source Biological Art, DIY Biology Generic lab equipment

"4. Genspace and BioCurious For letting the everyman explore the hidden corners of science. Community laboratories like Genspace, based in Brooklyn, New York, and BioCurious, based in Sunnyvale, California, are attracting biotech hackers interested in bridging the gulf that separates synthetic biology researchers from, well, everyone else"

"Sleep and its role in memory consolidation The role of sleep in the honeybee memory consolidation has been addressed in our lab in two studies so far. Hussaini et al. (2009; http://www.neurobiologie.fu-berlin.de/menzel/Pub_AGmenzel/Sleep Deprivation.pdf) found reduced retention after extinction learning in an olfactory PER experiment if bees are prevented from sleep during the night following extinction learning. Beyaert, Greggers and Menzel tested freely flying bees after navigation learning and found reduced homing rates if the bees could not sleep the night after novel navigation learning (see Beyaert L, Greggers U and Menzel R (2012) Honeybees consolidate navigation memory during sleep. Journal of Experimental Biology 215, 3981-3988"

"But over the century-plus that the prize has been awarded, the Nobel Committees have increasingly seen fit to reward not discoveries, but technological innovations that enable more discoveries. After all, these might confer a greater "benefit to mankind" than any individual discovery. Two examples: PCR and GFP"

""Der Mann, der die Epigenetik populär machte" (Deutschlandfunk). Geboren 1965 in Frankfurt am Main, studierte ich in Marburg und Hamburg Biologie, Anthropologie und Psychologie. Unterstützt von einem Stipendium der Studienstiftung des Deutschen Volkes (Danke!) promovierte ich im Bereich der Neurobiologie am Zoologischen Institut in Hamburg."

"Meist verursachen mechanische Reize jedoch unsichtbare Veränderungen. Viele Pflanzen reagieren nur auf molekularer und genetischer Ebene. Die Acker-Schmalwand etwa flutet ihre Zellen mit Calcium und schüttet reaktive Sauerstoffverbindungen aus, sobald sie mechanischem Stress ausgesetzt ist. Dabei reicht es, die Blätter vorsichtig zwischen Daumen und Zeigefinger zu reiben, wie Lehcen Benikhlef von der Universität Freiburg in der Schweiz und seine Kollegen nun herausfanden. Wie sie in der Fachzeitschrift „BMC Plant Biology" beschreiben, ändert sich auch die Genexpression in den gestreichelten Blättern. Außerdem wird die äußerste Schicht des Blattes durchlässiger - vermutlich, damit der Cocktail aus Chemikalien besser austreten kann, der Angreifer fernhalten soll. "

"Medical Museion is hosting an open biology (or "biohacking") laboratory and a series of hands-on public events from January-March 2013. The events are part of the European network, Studiolab, that provides a platform for creative projects that bridge divides between science, art and design"