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A new new brain imaging system that can identify a subject's simple thoughts may lead to clearer diagnoses for Alzheimer's disease or schizophrenia - as well as possibly paving the way for reading people's minds. Michael Greicius at Stanford University in California and colleagues used functional magnetic resonance imaging (fMRI) to identify patterns of brain activity associated with different mental states. He asked 14 volunteers to do one of four tasks: sing songs silently to themselves; recall the events of the day; count backwards in threes; or simply relax. Participants were given a 10-minute period during which they had to do this. For the rest of that time they were free to think about whatever they liked. The participants' brains were scanned for the entire 10 minutes, and the patterns of connectivity associated with each task were teased out by computer algorithms that compared scans from several volunteers doing the same task. This differs from previous experiments, in which the subjects were required to perform mental activities at specific times and the scans were then compared with brain activity when they were at rest. Greicius reasons his method encourages "natural" brain activity more like that which occurs in normal thought.

""We've developed the enabling technologies to create upper-extremity prosthetics that are more natural in appearance and use, a truly revolutionary advancement in prosthetics," said APL's Michael McLoughlin, the program manager. "Now, in Phase 3, we are ready to test it with humans to demonstrate that the system can be operated with a patient's thoughts and that it can provide that patient with sensory feedback, restoring the sensation of touch.""

Jesse Sullivan, the man in this video, is using one of the most high-tech prosthetic arms available. But what's truly impressive about it isn't visible to the eye: instead of using a motor, he's controlling the arm with his thoughts. After an amputation, the nerves in a stump remain healthy, at least for a while, and now scientists are making use of this fact to create highly dexterous, thought-controlled prosthetics.

With its expansive range and unprecedented potential for anonymity, (the Internet gives voice to our deepest urges and most uninhibited thoughts. Inspired by the wealth of unfettered expression available online, neuroscientists Ogi Ogas and Sai Gaddam, who met as Ph.D. candidates at Boston University, began plumbing a few chosen search engines (including Dogpile and AOL) to create the world's largest experiment in sexuality in 2009. Quietly tapping into a billion Web searches, they explored the private activities of more than 100 million men and women around the world. The result is the first large-scale scientific examination of human sexuality in more than half a century, since biologist Alfred Kinsey famously interviewed more than 18,000 middle-class Caucasians about their sexual behavior and published the Kinsey reports in 1948 and 1953. Building on the work of Kinsey, neuroscientists have long made the case that male and female sexuality exist on different planes. But like Kinsey himself, they have been hampered by the dubious reliability of self-reports of sexual behavior and preferences as well as by small sample sizes. That is where the Internet comes in. By accessing raw data from Web searches and employing the help of Alexa-a company that measures Web traffic and publishes a list of the million most popular sites in the world-Ogas and Gaddam shine a light on hidden desire, a quirky realm of lust, fetish, and kink that, like the far side of the moon, has barely been glimpsed. Here is a sampling of their fascinating results, selected from their book, A Billion Wicked Thoughts.

More than 50 severely disabled people in Second Life have been trying out a sophisticated new brain-computer interface (BCI) that lets users freely explore Second Life's virtual world and control their real-world environment. The system was developed by medical engineering company G.Tec of Schiedlberg, Austria as part of a pan-European project called Smart Homes for All. It's the first time the latest BCI technology has been combined with smart-home technology and online gaming. To activate a command, the user focuses their attention on the corresponding icon on a screen. Electroencephalograph (EEG) caps pick up brain signals, which are translated into commands to navigate and communicate within Second Life and Twitter. It can also be used to open and close doors, answer the phone, and control the TV, lights, thermostat, and intercom. G.Tec's system has been tested at the Santa Lucia Foundation Hospital in Rome, Italy.

Great link. Thanks

Free Download - StanfordUniversity - January 22, 2009 - Karl Deisseroth is pioneering bold new treatments for depression and other psychiatric diseases. By sending pulses of light into the brain, Deisseroth can control neural activity with remarkable precision. In this short talk, Deisseroth gives an thoughtful and awe-inspiring overview of his Stanford University lab's groundbreaking research in "optogenetics".

How do we relate human thought processes to measurable events in the brain? Mental chronometry, which has origins that date back more than a century, seeks to measure the time course of mental operations in the human nervous system [1]. From the late 1800s until 1950, the field was built almost entirely around a single method: measuring and comparing people's reaction times during simple cognitive tasks.

Our brain is the most complex object in the known universe - so we'll need to map it in formidable detail to track down memory, thought and identity

Aaron O'Connell and colleagues at the University of California, Santa Barbara, did not actually produce a cat that was dead and alive at the same time, as Erwin Schrödinger proposed in a notorious thought experiment 75 years ago. But they did show that a tiny resonating strip of metal - only 60 micrometres long, but big enough to be seen without a microscope - can both oscillate and not oscillate at the same time. Alas, you couldn't actually see the effect happening, because that very act of observation would take it out of superposition.

(PhysOrg.com) -- A group of physicists working out of Chalmers University of Technology in Gothenburg, Sweden, have succeeded in proving what was until now, just theory; and that is, that visible photons could be produced from the virtual particles that have been thought to exist in a quantum vacuum. In a paper published on arXiv, the team describes how they used a specially created circuit called a superconducting quantum interference device (SQUID) to modulate a bit of wire length at a roughly five percent of the speed of light, to produce visible "sparks" from the nothingness of a vacuum.

Vera Gorbunova and Andrei Seluanov of the University of Rochester have found that human cells undergoing oxidative stress caused by environmental chemicals or routine cellular processes produce a protein (SIRT6) that stimulates cells to repair DNA double-strand breaks, thought to be associated with premature aging and cancer. The team first measured levels of SIRT6 in stressed cells, then treated a second group of stressed cells with a drug that deactivates the protein. DNA repair in the second group stopped, confirming SIRT6′s role.  The team also found that SIRT6 acts in concert with another protein, called PARP1, to make the repairs. Furthermore, the team found that increased levels of SIRT6 lead to faster DNA repair. They suspect that the protein acts as a "master regulator," coordinating stress and DNA repair activities. Ref.: Zhiyong Mao, Christopher Hine, Xiao Tian, Michael Van Meter, Matthew Au, Amita Vaidya, Andrei Seluanov, and Vera Gorbunova. SIRT6 Promotes DNA Repair Under Stress by Activating PARP1. Science 17 June 2011: 1443-1446. [DOI:10.1126/science.1202723]

short summary of some probabilistic responses to the problem of induction