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Changul Louis Yeum

Changes in Social Status Seen in Monkeys' Genes - 1 views

www.nytimes.com/...tus-seen-in-monkeys-genes.html

Genes gene

shared by Changul Louis Yeum on 12 Apr 12 - No Cached
  • Changul Louis Yeum on 12 Apr 12
     
    Social stress is known to have adverse health effects on both humans and primates. Now, researchers report that it also affects the immune system of female rhesus macaques at the genetic level.
Mickey Tsai

Niceness a combination of genetics and environment, the Neurogenics of Niceness study f... - 0 views

www.heraldsun.com.au/...story-fn7x8me2-1226324345541

genetics environment research

shared by Mickey Tsai on 14 Apr 12 - No Cached
  • BEING a nice person could come down to having a good set of genes
  • "kind" behaviour of more than 700 individuals was partly linked to receptor genes for oxytocin and vasopressin.
  • uch of the hormone you have, it's how responsive your brain is to the hormo
  • ...2 more annotations...
  • It's not about how much of the hormone you have, it's how responsive your brain is to the hormones
  • "(Niceness) is a combination of genetics and your environment."
  • Mickey Tsai on 14 Apr 12
     
    A study shows that genetics could play a role in determining "niceness". The kind behavior is found to be linked to receptor genes for oxytopic and vasopressin. People that are more responsive to it are more inclined to donate money, pay taxes, give blood, report crime etc. It isn't about how much of the hormone you have but how responsive you are to it. Of course genetics isnt the only factor, if you are surrounded by nice people it is likely that it would rub off on you.
Kantham Hongdusit

Long-term in vivo expression of retrovirus-mediated gene transfer in mouse fibroblast i... - 1 views

www.pnas.org/...4626.full.pdf+html

shared by Kantham Hongdusit on 16 Apr 12 - No Cached
  • Kantham Hongdusit on 16 Apr 12
     
    A long term foreign gene expression can be embedded/transferred if a housekeeping gene promoter is present to drive the transcription. A mouse embryo fibroblast implants can be achieved when the embryo is embedded in a collagen matrix, which is a proof of the theory.
Kantham Hongdusit

Inducible gene expression from the plastid genome by a synthetic riboswitch - 0 views

www.pnas.org/...6204.full

shared by Kantham Hongdusit on 16 Apr 12 - No Cached
  • Kantham Hongdusit on 16 Apr 12
     
    Riboswitches, natural RNA sensors that mediate the control of gene expression by beinding with metabolites, are engineered via a simulation to meet the requirements of translational regulation in organelles. These new riboswitches are able facilitate the expression of chloroplast genes
Kaoko Miyazaki

Genetics as Rorschachs: Pondering Our Genes and Our Fate | Psychology Today - 0 views

www.psychologytoday.com/...ndering-our-genes-and-our-fate

genetics disease

shared by Kaoko Miyazaki on 01 Apr 12 - No Cached
  • Kaoko Miyazaki on 01 Apr 12
     
    Even today scientists find the study of genes an ambiguous topic. The randomness of the genes being passed down or not, whether one child has a mutations while the other does not or if your sister has a higher risk of getting breast cancer than you is still being tested.
Paige Prescott

Genes Are No Crystal Ball For Disease Risk - Science News - 0 views

www.sciencenews.org/..._crystal_ball_for_disease_risk

genes disease

shared by Paige Prescott on 14 Apr 12 - No Cached
  • For all but four diseases, the genetic data would fail to determine who is likely to contract the condition in most cases,
  • genetics are only part of the story when it comes to determining health. Lifestyle, environment and random chance play a bigger role than genes, or work with genes, to cause or protect against disease.
  • Paige Prescott on 14 Apr 12
     
    Looking at twin data, researchers found that genetics alone could not account for the risk of disease.
Rafael Chen

Plant Geneticist Identifies Drought-Tolerant Gene - 2 views

www.sciencedaily.com/...981028144738.htm

shared by Rafael Chen on 16 Apr 12 - No Cached
  • isolation of the gene that controls drought tolerance in plants
  • enable a plant's leaves to stay green long after the last watering
  • plant hormone abscisic acid triggers the closure of the plant's stomata
  • ...3 more annotations...
  • controlled by the ERA1
  • By suppressing the gene -- and thereby keeping the stomata closed -- he found it is possible to control water loss so plants last longer
  • useful in applications such as the cut flower industry
  • Rafael Chen on 16 Apr 12
     
    Genetically engineering plants with a drought resistant gene may be beneficial in creating plants whom leaves would stay green long after the last watering.
Pop karnchanapimonkul

Dieting During Pregnancy Increases Risk Of Obesity And Diabetes For Offspring - 0 views

www.medicalnewstoday.com/...243627.php

dieting obesity diabetes epigenics offspring

shared by Pop karnchanapimonkul on 14 Apr 12 - No Cached
  • babies of mothers who diet around the time of conception and in early pregnancy, may have an increased risk of obesity and type 2 diabetes throughout their lives. This study provides exciting insights into how behavior can lead to epigenetic changes in offspring related to obesity and disease.
  • dieting around the time a baby is conceived may increase the chance of the child becoming obese later in life
  • changes in the genes that control food intake and glucose levels that may lead to obesity and diabetes.
  • ...1 more annotation...
  • epigenetic changes with alterations in the structure of the DNA and its associated proteins, histones, which affects the way that genes can behave in later life.
  • Pop karnchanapimonkul on 14 Apr 12
     
    Article about how dieting during pregnancy cause offsprings to have a change in genes.
Kantham Hongdusit

Gene transfer to human joints: Progress toward a gene therapy of arthritis - 0 views

www.pnas.org/...8698.full

shared by Kantham Hongdusit on 16 Apr 12 - No Cached
  • Kantham Hongdusit on 16 Apr 12
     
    Rheumatoid Arthritis is an incurable disease that is often difficult to treat. The article describes how a transfer of cultured synovial fibroblasts can increase the amount of IL-1Ra receptor, which offers a therapeutic gene that can be used to obtain intra articular transgene expression.
nidthamsirisup

Epigenetics: DNA Isn't Everything - 0 views

www.sciencedaily.com/...090412081315.htm

epigenetics genetics gene

shared by nidthamsirisup on 15 Apr 12 - Cached
  • Research into epigenetics has shown that environmental factors affect characteristics of organisms. These changes are sometimes passed on to the offspring.
  • A certain laboratory strain of the fruit fly Drosophila melanogaster has white eyes. If the surrounding temperature of the embryos, which are normally nurtured at 25 degrees Celsius, is briefly raised to 37 degrees Celsius, the flies later hatch with red eyes.
  • crossed the flies for six generations. In this experiment, they were able to prove that the temperature treatment changes the eye colour of this specific strain of fly, and that the treated individual flies pass on the change to their offspring over several generations. However, the DNA sequence for the gene responsible for eye colour was proven to remain the same for white-eyed parents and red-eyed offspring.
  • ...7 more annotations...
  • Epigenetics examines the inheritance of characteristics that are not set out in the DNA sequence.
  • important factors are the histones, a kind of packaging material for the DNA, in order to store DNA in an ordered and space-saving way. It is now clear that these proteins have additional roles to play. Depending on the chemical group they carry, if they are acetylated or methylated, they permanently activate or deactivate genes.
  • New methods now allow researchers to sometimes directly show which genes have been activated or deactivated by the histones
  • The genetic information of the DNA is passed on along with the relevant epigenetic information for the respective cell type.
  • A similar question remains for the inheritance of the epigenetic characteristics from parents to offspring. They now know that when the gametes are formed, certain epigenetic markers remain and are passed on to the offspring. The questions, which are currently being researched, are how much and which part of the epigenetic information is preserved and subsequently inherited.
  • Diet and epigenetics appear to be closely linked. The most well known example is that of the Agouti mice: they are yellow, fat and are prone to diabetes and cancer. If Agouti females are fed with a cocktail of vitamin B12, folic acid and cholin, directly prior to and during pregnancy, they give birth to mainly brown, slim and healthy offspring. They in turn mainly have offspring similar to themselves.
  • Environmental factors, which change the characteristics of an individual and are then passed on to its offspring, do not really fit into Darwin’s theory of evolution. According to his theory, evolution is the result of the population and not the single individual. “Passing on the gained characteristics fits more to Lamarck’s theory of evolution”, says Paro.
pet-chompoo sa-ngarmangkang

Heart Failure Gene Discovered...In the Kidney - St. Louis News - Daily RFT - 0 views

blogs.riverfronttimes.com/...ure_gene_prevention_kidney.php

shared by pet-chompoo sa-ngarmangkang on 07 Apr 12 - No Cached
  • risk for heart failure
  • e high blood pressure
  • t's related to the kidney.
  • ...8 more annotations...
  • "It also makes hormones involved in maintaining blood volume."
  • So they began sequencing the kidney gene, looking for problems.
  • "The CLCNKA polymorphism decreases the kidney's functionality by about half,"
  • gene remains silent with no effect on the body until there's an injury to the heart
  • the blood flow to the kidney decreases and the kidney secretes the hormones angiotensin and aldosterone which lead to a high risk of heart failure."
  • More blood with less space to move leads to high blood pressure
  • puts more pressure on the heart.
  • presence of the gene drives the risk of heart failure from 20 percent to 27 percent for people with one copy and 54 percent for people with two
pet-chompoo sa-ngarmangkang

Craving Coffee? It Might Be in Your Genes - Slashfood - 0 views

www.slashfood.com/...ffee-it-might-be-in-your-genes

shared by pet-chompoo sa-ngarmangkang on 07 Apr 12 - No Cached
  • 3 o'clock caffeine craving can also be traced back to your gene
  • depending on whether you carry a "high-consumption" variant or "low-consumption" variant of either gene determines just how fast or slow you metabolize caffeine
  • genetics plays a big role in a lot of behaviors, such as smoking and alcohol consumption
  • ...2 more annotations...
  • how much caffeine we drink."
  • CYP1A2 and AHR,
Nitchakan Chaiprukmalakan

Plant research reveals new role for gene silencing protein - 0 views

www.sciencedaily.com/...120329141923.htm

shared by Nitchakan Chaiprukmalakan on 02 Apr 12 - No Cached
    • wasin kusakabe
      wasin kusakabe on 02 Apr 12
       
      Termination is equally as important as other sections of Transcription
  • Termination is the final stage of transcription.
  • Without termination, transcription continues down the chromosome unchecked.
  • ...3 more annotations...
  • The expression of a gene, when an organism's DNA is transcribed into a useable product, requires activation via a promoter or an external trigger.
  • DCL4 is a back-up to termination processes, helping a gene to be successfully expressed
  • If a gene ends badly, aberrant RNA will trigger silencing pathways
  • Sea Maskulrath on 02 Apr 12
     
    this new way to making the mature mRNA is very interesting. gotta love it. 
orasa sukmark

Gene therapy - 0 views

www.sciencedaily.com/...gene_therapy.htm

gene therapy

shared by orasa sukmark on 02 Apr 12 - No Cached
  • orasa sukmark on 02 Apr 12
     
    general info on gene therapy
avikan

New Hope Of a Cure For H.I.V. - NYTimes.com - 0 views

query.nytimes.com/...fullpage.html

shared by avikan on 11 Apr 12 - No Cached
  • So people with H.I.V. now must take drugs every day for life, which some researchers say is not a sustainable solution for tens of millions of infected people.
  • CCR5,
  • This is what was done with the Trenton patient. Some of the man's white blood cells were removed from his body and treated with a gene therapy developed by Sangamo BioSciences. The therapy induced the cells to produce proteins called zinc-finger nucleases that can disrupt the CCR5 gene.
  • ...5 more annotations...
    • avikan
      avikan on 11 Apr 12
       
      Millions of people worldwide are currently affected by HIV and many have died from AIDS. Scientists have been trying for many years to find a cure for the epidemic, but now many are trying to find a way to prevent the passing on of the virus for future generations. Although no definite treatment has been discovered yet, recent findings have shown promising results for the future. 
    • avikan
      avikan on 11 Apr 12
       
      With the fast developing biological technologies we are seeing today, scientists hope's are growing stronger.  Maybe one of us one day will be a part of the phenomenon, in search of a way to help the millions affected by the epidemic  
    • avikan
      avikan on 11 Apr 12
       
      CD4 cells initiate the body's response to infections.
    • avikan
      avikan on 11 Apr 12
       
      Many forms of HIV, initially use CCR5 to enter and infect host cells. A few individuals carry a mutation known as CCR5 delta 32 in the CCR5 gene, protecting them against these strains of HIV.
    • avikan
      avikan on 11 Apr 12
       
      For over 30 years scientists have been trying to find a cure for the HIV/AIDs epidemic and so far have been unsuccessful 
    • avikan
      avikan on 11 Apr 12
       
      Incase some of us forgot, AIDs stands for Acquired immune deficiency syndrome, a disease in which there is a severe loss of the body's cellular immunity. And HIV stands for Human immunodeficiency virus, a virus that causes AIDs
Pop karnchanapimonkul

Genetic adaptation of fat metabolism key to development of human brain - 0 views

www.sciencedaily.com/...120412133056.htm

adaptation fat metabolism brain human gene

shared by Pop karnchanapimonkul on 13 Apr 12 - No Cached
  • 300,000 years ago humans adapted genetically to be able to produce larger amounts of Omega-3 and Omega-6 fatty acids. This adaptation may have been crucial to the development of the unique brain capacity in modern humans.
  • higher risk of developing disorders like cardiovascular disease.
  • investigated the genes for the two key enzymes that are needed to produce Omega-3 and Omega-6 fatty acids from vegetable oils.
  • ...7 more annotations...
  • genetic adaptation for high production of Omega-3 and Omega-6 fatty acids is found only in humans
  • 300 000 years ago in the evolutionary line that led to modern humans
  • important factor for human survival in environments with limited dietary access to fatty acids
  • In today’s life situation, with a surplus of nourishment, this genetic adaptation contributes instead to a greater risk of developing disorders like cardiovascular disease
  • first study to show a genetic adaptation of human fat metabolism
  • thrifty gene
  • adaptation that contributed to enhanced survival in an earlier stage of human development, but in a life situation with an excess of food instead constitutes a risk factor for lifestyle diseases
  • Pop karnchanapimonkul on 13 Apr 12
     
    This article explains how earlier genetic adaptations that help our survival is now harming us.
pet-chompoo sa-ngarmangkang

BBC News - 'Tipsy' alcohol gene 'could help curb alcoholism' - 0 views

www.bbc.co.uk/...health-11572894

shared by pet-chompoo sa-ngarmangkang on 07 Apr 12 - No Cached
  • people who react strongly to alcohol are less likely to become addicted
  • the gene we have found tells us a lot about how alcohol affects the brain
  • Most of the alcohol people consume is broken down in the liver, but some is metabolised in the brain by an enzyme which the CYP2E1 gene
  • ...2 more annotations...
  • "tipsy" version of CYP2E1 break down alcohol more readily, which explains why they feel the effects of alcohol much quicker than others
  • CYP2E1 on chromosome 10 appears to dictate whether a person can hold their drink better than others.
Nickyz P.

Exercise Brings On DNA Changes - Science News - 2 views

www.sciencenews.org/...Exercise_brings_on_DNA_changes

shared by Nickyz P. on 30 Mar 12 - No Cached
  • These alterations turn on genes that regulate a cell’s energy.
  • Genes can be turned on or off  by a process known as methylation, in which a methyl group — consisting of one carbon atom and three hydrogen atoms — is added to DNA.
Sea Maskulrath

Boffins set mammoth cloning task - 0 views

www.heraldsun.com.au/...story-fn5iztw3-1226298850815

gene cloning

shared by Sea Maskulrath on 09 Apr 12 - No Cached
  • Sea Maskulrath on 09 Apr 12
     
    As it has been stated in the news, Russia and south Korean scientist has been working together in this cloning project in order to compress the gene of mammoth into an embryo ,which then will be placed into the womb of an indian elephant. if successful, they will be able to recreate the mammoth :) WOW
chanon chiarnpattanodom

Genes an important factor in urinary incontinence - 1 views

www.sciencedaily.com/...110404142807.htm

Urinary Incontinence Genes

shared by chanon chiarnpattanodom on 11 Apr 12 - No Cached
  • chanon chiarnpattanodom on 11 Apr 12
     
    Scientists have studied how much is urinary incontinence controlled by genetics, rather than the environment by observing twins. 
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