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Contents contributed and discussions participated by Kaoko Miyazaki

Kaoko Miyazaki

Long Intergenic Noncoding RNAs: New Links in Cancer Progression - 1 views

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    The newly discovered and currently being researched lincRNAs are seen to be one of the causes of cancer. The function of lincRNAs to control gene expression by regulating the number of histones according to specific chromatin, may cause cancer when done wrong or are altered in some way. The epigenetic alterations that occur when this function is done wrong may lead to the disease and the inheritance of it. Which could be hypothesized as to why people with a history of cancer (and other diseases) within their families have higher likelihood to being diagnosed with the disease. But because lincRNA is a very recent discovery and only less than 1% of it has has been characterized in the human body, evidence of this is still being researched, tested and studied.
Kaoko Miyazaki

lincRNA: A recently discovered RNA organizes stem cell differentiation - 0 views

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    Organizing how proteins assemble in embryonic cells and taking control over/deciding whether a stem cells stays pluripotent or not are only two of the main functions of the recently discovered lincRNAs. These new discoveries of lincRNAs and ongoing experiments only help researches such as Mitchell Guttman from the Broad Institute widen up the study of genetics and the human genome to a new field.
Kaoko Miyazaki

The Rinn Lab - 0 views

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    John Rinn (RNA researcher at Harvard Medical School) continues on his ongoing research about Long Intergenic Noncoding RNA's (lincRNAs). lincRNAs used to be overlooked and classified as 'waste' products, but today it is seen as the contractors that create the DNA's coding sequence needed for the organism's structure. In simpler terms, lincRNAs are responsible for putting molecular materials in places they are supposed to be - as though following a rough draft to make a final master piece. Because lincRNAs have so many functions, if step goes wrong, it could cause potential harm to the organism such as creating a tumor. But because of their many functions like guiding the interactions of protein DNA to name one, John Rinn and other current scientists hypothesize that lincRNAs are what differentiates us from other organisms and makes us, us.
Kaoko Miyazaki

Genetics as Rorschachs: Pondering Our Genes and Our Fate | Psychology Today - 0 views

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    Even today scientists find the study of genes an ambiguous topic. The randomness of the genes being passed down or not, whether one child has a mutations while the other does not or if your sister has a higher risk of getting breast cancer than you is still being tested.
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