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orasa sukmark

Genetic adaptation of fat metabolism key to development of human brain - 0 views

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    Genetic adaptation for high production of Omega-3 and Omega-6 fatty acids is found only in humans can show genetic adaptation of human fat metabolism.
Pop karnchanapimonkul

Genetic adaptation of fat metabolism key to development of human brain - 0 views

  • 300,000 years ago humans adapted genetically to be able to produce larger amounts of Omega-3 and Omega-6 fatty acids. This adaptation may have been crucial to the development of the unique brain capacity in modern humans.
  • higher risk of developing disorders like cardiovascular disease.
  • investigated the genes for the two key enzymes that are needed to produce Omega-3 and Omega-6 fatty acids from vegetable oils.
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  • genetic adaptation for high production of Omega-3 and Omega-6 fatty acids is found only in humans
  • 300 000 years ago in the evolutionary line that led to modern humans
  • important factor for human survival in environments with limited dietary access to fatty acids
  • In today’s life situation, with a surplus of nourishment, this genetic adaptation contributes instead to a greater risk of developing disorders like cardiovascular disease
  • first study to show a genetic adaptation of human fat metabolism
  • thrifty gene
  • adaptation that contributed to enhanced survival in an earlier stage of human development, but in a life situation with an excess of food instead constitutes a risk factor for lifestyle diseases
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    This article explains how earlier genetic adaptations that help our survival is now harming us.
pet-chompoo sa-ngarmangkang

Craving Coffee? It Might Be in Your Genes - Slashfood - 0 views

  • 3 o'clock caffeine craving can also be traced back to your gene
  • depending on whether you carry a "high-consumption" variant or "low-consumption" variant of either gene determines just how fast or slow you metabolize caffeine
  • genetics plays a big role in a lot of behaviors, such as smoking and alcohol consumption
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  • how much caffeine we drink."
  • CYP1A2 and AHR,
nidthamsirisup

Study suggests why some animals live longer - 1 views

    • nidthamsirisup
       
      A new method to detect proteins associated with longevity which helps further our understanding into why some animals live longer than others.
  • found a similar pattern in proteins associated with metabolism, cholesterol and pathways involved in the recycling of proteins
  • these species have optimised pathways that repair molecular damage, compared to shorter-lived animals, such as mice
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  • The study, led by Dr. Joao Pedro Magalhaes and postgraduate student, Yang Li, is the first to show evolutionary patterns in biological repair systems in long-lived animals and could, in the future, be used to help develop anti-ageing interventions by identifying proteins in long-lived species that better respond to, for example, DNA damage
  • Proteins associated with the degradation of damaged proteins, a process that has been connected to ageing, were also linked with the evolution of longevity in mammals.
  • If we can identify the proteins that allow some species to live longer than others we could use this knowledge to improve human health and slow the ageing process.
  • “We developed a method to detect proteins whose molecular evolution correlates with longevity of a species. The proteins we detected changed in a particular pattern, suggesting that evolution of these proteins was not by accident, but rather by design to cope with the biological processes impacted by ageing, such as DNA damage. The results suggest that long-lived animals were able to optimise bodily repair which will help them fend off the ageing process.”
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