PHE - Resources

Yu was intrigued. He reached out and offered to do whole-genome sequencing on Mila, her parents, and her younger brother.

Julia Vitarello, Mila's mother In March, Yu’s team found that a piece of DNA called a retrotransposon—the genetic remnants of viruses scattered throughout all of our genomes—had spontaneously inserted itself in the middle of a noncoding region of Mila’s CLN7 gene.

Black told Yu to renegotiate with the FDA. The 3-month safety study in rats, followed by another couple months to report the data, would take too long. After a letter from Vitarello outlining Mila’s decline, the FDA made a concession: Mila could get the drug after just 1 month of testing, so long as the rat studies continued to 3 months to understand any long-term toxicity.

Today, Mila continues to get injections of her drug approximately every 2 months. She used to have up to 30 seizures a day, each lasting more than a minute. Now, she only has a few a day, and they don’t last long,

PRODUCER & WRITER

What’s more important, quality of life or quantity?”

Theresa learned early that age is not an excuse to slow down.

Through storytelling, she wants to break the stereotypes associated with aging.

This series convinced Heidi that life should be measured in quality not quantity

Obviously, the data collected shortly after the 1917-1918 pandemic must be treated cautiously.

In 1918, C.P. McConnell, DO,11 reported that the most effective treatment during the influenza pandemic was begun early in the onset of symptoms (within the first 24 hours) and consisted of carefully applied muscular relaxation and, most importantly, relaxation of the deep and extensive contractions of the deep spinal musculature and mobilization of the spine. These treatments would be repeated two or three times early in the course of the infection, along with traditional supportive measures such as hydration. During later influenza epidemics, such as the 1928-1929 and the 1936-1937 outbreaks, various lymphatic pump treatments and more attention to the cervical and upper thoracic regions were added to this recommended treatment protocol.12 These treatments, individualized to each patient's needs, were apparently the most commonly applied osteopathic medical procedures during the epidemics. 

action of these treatments were to diminish somatic inputs from contracted muscles

that had further stimulated the already overactive sympathetic system

hyperreactivity exacerbated the counterproductive and deadly immune respons

OMT) likely enhanced lymphatic drainage and encouraged appropriate immune response

we have no controlled data on the effects of OMT on the pandemic influenza

Noll et al13 demonstrated that OMT given to elderly patients with pneumonia decreases medication use and hospital stay

Whatever the mechanism, these beneficial outcomes have taught us a great deal about how the osteopathic medical profession might handle a coming pandemic.

treatments used back then can be used again and do not require patient hospitalization

methods can also be taught to family members

do not rely on the availability of potent, expensive, and often harmful (especially when one is in a weakened condition) medications.

treatments can be delivered by osteopathic medical students under the direction of a physician—a measure that would add significantly to the pool of trained healthcare providers available to assist the public in such an emergency.

OMT is meant to improve function, enabling the body itself to better