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Dennis OConnor

Fast ForWord Reading Intervention and Evidence for ESSA | Scientific Learning - 0 views

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    "Fast ForWord has 21 studies that meet WWC Evidence Standards for Adolescent Literacy, Beginning Reading and English Language Development - the most of any reading intervention evaluated. Positive effectiveness ratings and improvement indices were found for: Alphabetics Reading Fluency Comprehension English Language Development (largest improvement index of interventions evaluated) When compared to other interventions evaluated by WWC, Fast ForWord is the only intervention with positive effects for English Learner AND Literacy Outcomes for students grades K-10 in individual, small group, and whole class settings."
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    Keywords: neuroscience reading
Dennis OConnor

Our Founders' Story | Scientific Learning - 0 views

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    "The story of Scientific Learning begins with four research scientists: Michael Merzenich, William Jenkins, Paula Tallal, and Steven Miller. When the work of these four scientists intersected, their collaboration proved that the underlying cognitive processes that influence speech and language problems could be identified-and permanently improved. These findings led to the development of the Fast ForWord program, a groundbreaking computer-based reading intervention. The scientists then founded Scientific Learning to bring their program out of the lab and into the lives of struggling readers."
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    Keywords: neuroscience reading
Dennis OConnor

Fast ForWord Language & Reading Intervention | Scientific Learning - 0 views

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    Keywords: neuroscience reading
Dennis OConnor

Which Covid-19 Data Can You Trust? - 0 views

  • incomplete or incorrect data can also muddy the waters, obscuring important nuances within communities, ignoring important factors such as socioeconomic realities, and creating false senses of panic or safety, not to mention other harms such as needlessly exposing private information.
  • Right now, bad data could produce serious missteps with consequences for millions.
  • Whether you’re a CEO, a consultant, a policymaker, or just someone who is trying to make sense of what’s going on, it’s essential to be able to sort the good data from the misleading — or even misguided.
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  • common red flags
  • Data products that are too broad, too specific, or lack context.
  • Public health practitioners and data privacy experts rely on proportionality
  • only use the data that you absolutely need for the intended purpose and no more.
  • Even data at an appropriate spatial resolution must be interpreted with caution — context is key.
  • Simply presenting them, or interpreting them without a proper contextual understanding, could inadvertently lead to imposing or relaxing restrictions on lives and livelihoods, based on incomplete information.
  • The technologies behind the data are unvetted or have limited utility.
  • Both producers and consumers of outputs from these apps must understand where these can fall short.
  • In the absence of a tightly coupled testing and treatment plan, however, these apps risk either providing false reassurance to communities where infectious but asymptomatic individuals can continue to spread disease, or requiring an unreasonably large number of people to quarantine.
  • Some contact-tracing apps follow black-box algorithms, which preclude the global community of scientists from refining them or adopting them elsewhere.
  • These non-transparent, un-validated interventions — which are now being rolled out (or rolled back) in countries such as China, India, Israel and Vietnam — are in direct contravention to the open cross-border collaboration that scientists have adopted to address the Covid-19 pandemic.
  • Models are produced and presented without appropriate expertise.
  • Epidemiological models that can help predict the burden and pattern of spread of Covid-19 rely on a number of parameters that are, as yet, wildly uncertain.
  • n the absence of reliable virological testing data, we cannot fit models accurately, or know confidently what the future of this epidemic will look like
  • and yet numbers are being presented to governments and the public with the appearance of certainty
  • Read Carefully and Trust Cautiously
  • Transparency: Look for how the data, technology, or recommendations are presented.
  • Thoughtfulness: Look for signs of hubris.
  • Example: Telenor
  • Expertise: Look for the professionals. Examine the credentials of those providing and processing the data.
  • Open Platforms: Look for the collaborators.
  • technology companies like Camber Systems, Cubeiq and Facebook have allowed scientists to examine their data,
  • The Covid-19 Mobility Data Network, of which we are part, comprises a voluntary collaboration of epidemiologists from around the world analyzes aggregated data from technology companies to provide daily insights to city and state officials from California to Dhaka, Bangladesh
  • This pandemic has been studied more intensely in a shorter amount of time than any other human event.
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    "This pandemic has been studied more intensely in a shorter amount of time than any other human event. Our globalized world has rapidly generated and shared a vast amount of information about it. It is inevitable that there will be bad as well as good data in that mix. These massive, decentralized, and crowd-sourced data can reliably be converted to life-saving knowledge if tempered by expertise, transparency, rigor, and collaboration. When making your own decisions, read closely, trust carefully, and when in doubt, look to the experts."
Dennis OConnor

Empowering patients and reducing inequities: is there potential in sharing clinical not... - 0 views

  • engages them actively in their care, improves their sense of control over their health and enhances safety.
  • older, less educated, non-white or whose first language is not English report even greater benefits than do their counterparts
  • we suggest that open notes may, over time, prove important in the care of patients who are at risk of experiencing healthcare disparities.
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  • in the USA, the likelihood of receiving an access code to activate health portals is significantly lower for minorities, the uninsured, non-English speakers and older patients.11
  • Research suggests that negative implicit biases can affect the quality of health interactions and are associated with fewer signals of support and empathy towards patients representing some disadvantaged demographic groups, including racial and ethnic minorities, low-income, less educated and older patients.1
  • Open notes might be viewed as extending the visit, potentially thereby elongating and strengthening patient–physician interactions before and after the pressures of the clinical encounter.
  • investigators found that patients who were non-white or less educated reported more benefits than their counterparts:
  • Although some health organisations provide portals in a range of languages, clinical notes are typically offered in one language only.
  • access to open notes appears to help some patients who speak another primary language by allowing them, or a care partner, to read and recall information.
  • in a large study of patients who read notes, 38% (8588/22 753) reported sharing them with others, predominantly family members
  • It is estimated that, on average, patients do not recall about half of the health information communicated during visits, with this figure likely higher among those with lower levels of health literacy.2
  • health literacy is now recognised as a driver of health disparities.
  • By offering patients access to records that document what was discussed during visits, open notes may provide a novel forum for augmenting health literacy among some patients.
  • As one patient noted: “I like my summaries because I can go back and revisit them”.1
  • 77% (357/462) reported reading their notes as extremely important for remembering their care plan,
  • Limitations
  • Open notes are becoming increasingly common, and preliminary data suggest they may hold particular benefits for vulnerable patient populations
  • Second, as preliminary evidence suggests, it is possible that open notes may increase trust between patients and clinicians, reduce transmission of bias and increase patient engagement, especially among vulnerable patient populations
  • co-creation of medical notes holds promise and is currently under investigation
Dennis OConnor

Altman Clinical & Translational Research Institute, UC San Diego Health Sciences - 0 views

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    "Learn more Click here to subscribe to the CTRI News and Funding Opportunities monthly newsletter. Learn more   Director's Message I am pleased to announce the availability of the ACTRI Virtual Research Desktop (VRD) for UC San Diego Health research scientists and staff. The service is a collaboration between ACTRI and UC San Diego Health System Information Services (IS). The VRD is a HIPAA-compliant virtual desktop that operates in a secure private cloud server environment managed by the ACTRI and housed in a UC San Diego data center. Read more from Director Gary S. Firestein, MD"
Dennis OConnor

Qigong - Diving into Grace~A Well-Being Retreat - 0 views

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    "Dear Practitioners,   It is with great pleasure that Daniela Carraro and myself will be co-teaching a transformational retreat with Jianshe Liu on March 5 - 8th, 2019 at Prince of Peace Abbey in Oceanside.   Jianshe has studied Zhineng Qigong since 1991 - his teaching is a direct transmission of authentic,  joyful presence and living each moment gracefully.   Jianshe, Dani and I are honored and humbled to come together and connect with you in this way. Please read below for more details, we look forward to sharing this experience with you.   Abundant blessings, Dani & Reyna"
Dennis OConnor

Love 2.0 - Online Tools - 0 views

  • Positivity Self Test
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    Recommended by Kabir: "In both Love 2.0 and her earlier book, Positivity, Dr. Barbara Fredrickson describes ground breaking research on our supreme emotion, love, as well as the hidden value of all positive emotions. She encourages readers to experiment with their own lives, finding ways to create more micro-moments of love and positivity that work for them. One way to begin is to keep track of your emotions on a regular basis. Dr. Fredrickson developed the Positivity Self Test featured in her research, her books, and on this website to help you assess your current positivity ratio and track changes in your ratio over time. Just like tracking calories or cash flows can heighten your awareness and in time help you meet your fitness or financial goals, tracking your positivity ratio can help you raise your ratio and build your best future. Results may vary. Best outcomes emerge from sincere and heartfelt efforts to raise your ratio coupled with honest reports of your emotion experiences. Read more about the Positivity Self Test or take the survey here."
Dennis OConnor

Is Red Meat Really Good for You? | LinkedIn - 0 views

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    "The Annals of Internal Medicine just published a series of articles claiming: "New guidelines: No need to reduce red or processed meat consumption for good health. A rigorous series of reviews of the evidence found little to no health benefits for reducing red or processed meat consumption."   Yet a careful reading of these articles reveals the exact opposite! They found that dietary patterns with a moderate reduction in red and processed meat consumption had a 13% lower rate of premature death from all causes, a 14% reduction in cardiovascular disease mortality, an 11% decrease in cancer mortality, and a 24% decrease in the risk of type 2 diabetes.  "
Dennis OConnor

Chasing My Cure: Dr. David Fajgenbaum Lessons from his Rare Disease and On Finding Cure... - 0 views

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    "David Fajgenbaum, MD, MBA, MSc, is the co-founder and Executive Director of the Castleman Disease Collaborative Network (CDCN) and one of the youngest individuals to be appointed to the faculty at Penn Medicine, where he is an Assistant Professor of Medicine in Translational Medicine & Human Genetics, Founding Director of the Center for Study & Treatment of Castleman & inflammatory Lymphadenopathies (CSTL). An NIH-funded physician-scientist, he has dedicated his life to discovering new treatments and cures for deadly disorders like idiopathic multicentric Castleman disease (iMCD), which he was diagnosed with during medical school. As common as ALS and more deadly than lymphoma, iMCD involves the immune system attacking and shutting down the body's vital organs such as the liver, kidneys, bone marrow, and heart. After spending months hospitalized in critical condition, having his last rites read, and having four deadly relapses, he is now in his longest remission ever thanks to a treatment that he identified in the lab."
Dennis OConnor

The Coronavirus Conundrum: ACE2 and Hypertension Edition - NephJC - 0 views

  • Hypertension and COVID19
  • Are patients with hypertension more likely to get COVID19?For this, we need a well-designed cohort study with incidence rates of COVID19 in patients with hypertension (HT) and those without HT, in which exposure history is able to be carefully accounted for.
  • Amongst the patients with COVID19, it seems the prevalence of prior h/o HT is higher in those who develop severe disease than those who do not.
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  • Hypertension does seem to be a common comorbidity, even more so than diabetes - but these are all data from one country, so one should be careful before generalization.
  • Why might there be a link between high blood pressure and COVID19?As you can read so far, we are not convinced the data show a strong, robust link. However, the virus uses the renin-angiotensin system - hence all the speculation. Read about the science behind the speculation below.
  • Can ARB/ACEi use (and potentially increased ACE2) actually be beneficial in coronavirus and other viral pneumonias?This is an interesting question and has been looked at in both animal model and human studies (retrospective). This study looked at patients (humans) with viral pneumonia and demonstrated an association with improved outcomes in patients with continued ACEi use during viral pneumonia. However, you could argue that patients with viral pneumonia who had continued use of ACEi while hospitalized were not “as sick” as patients in which it was discontinued. 
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    Recommended by DeAunne Denmark, MD, PhD: "... this excellent international society and expert consensus site regarding anti-hypertensives and ACE2, the protein used by both SARS for host cell.
Dennis OConnor

Understanding Medical Research: Your Facebook Friend is Wrong | Coursera - 0 views

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    Recommended by Trish Makowiak: How can you tell if the bold headlines seen on social media are truly touting the next big thing or if the article isn't worth the paper it's printed on? Understanding Medical Studies, will provide you with the tools and skills you need to critically interpret medical studies, and determine for yourself the difference between good and bad science. The course covers study-design, research methods, and statistical interpretation. It also delves into the dark side of medical research by covering fraud, biases, and common misinterpretations of data. Each lesson will highlight case-studies from real-world journal articles. By the end of this course, you'll have the tools you need to determine the trustworthiness of the scientific information you're reading and, of course, whether or not your Facebook friend is wrong. This course was made possible in part by the George M. O'Brien Kidney Center at Yale.
Dennis OConnor

Health Literacy - CCMI - 0 views

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    "Empowering patients to have greater agency in, and control over health decisions. A patient's health literacy is their ability to read, understand and use health care information to make informed decisions and modify behaviours that affect their personal healthcare needs. Promoting health literacy among patients creates a more collaborative care environment, one that empowers patients to have greater agency in, and control over, their own care decisions. CCMI's Health Literacy programs introduce participants to concepts that support and emphasize the importance of being able to support patients and communicate clearly so that patients and family members can truly participate in care. Participants will gain an understating of Health Literacy concepts and learn practical skills for engaging with patients to ensure clear and effective communication."
Dennis OConnor

On Teaching: Learning From Black Educators - The Atlantic - 0 views

  • “You need a sincere love for children,” Grenell liked to remind Moore. “Never give up on a child.”
  • firm and demanding, but also warm and encouraging.
  • She was named Mississippi Teacher of the Year in 2001 and won the prestigious Milken Award.
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  • Students will go to great lengths to hide from me what they don’t know.
  • I do that very intentionally at the beginning of the semester to signal: “I see you as a human being. I’m paying attention to what you say to me. You are a unique individual with skills and ideas that matter.”
  • That’s important, because a lot of students have told me that no one’s ever actually read what they wrote. What they mean by that is that their writing has been graded, but it’s never been read.
  • Then, at the end of the semester, I give them the introduction letter back. And the final exam is an essay where they have to reflect on their portfolio: all of the written pieces they produced in the course of the semester.
  • they’re not used to measuring it in terms of actual skills and knowledge. They're always stunned at how far they’ve come.
  • The students have been so used to having their grammar criticized that they over-censor themselves when they’re writing.
  • The message was always, “When you go to college.” It was always, “You can do it.
  • “You get educated for the benefit of the community and the race.”
  • Today we have wasted a generation, telling young people that the primary reason to pursue education is to get into a well-paying career. In rural or economically depressed areas like Delta, looking at education chiefly as a path to social mobility—rather than a path to full citizenship, one’s sense of agency and freedom—can actually depress achievement and increase hopelessness. B
  • By attaching the dreams and aspirations of African American students to a higher good, their expectations are infused with a meaningful purpose.
  • For a lot of the kids now, school is just drudgery from beginning to end—particularly schools that serve poor Black students. There’s no music curriculum, no arts curriculum, no vocational classes.
  • They congratulated me, because I was going to Washington, D.C., to receive the award. These women had taken up money among themselves, put it in a handkerchief, tied it, and handed it to me, as a way to celebrate that I was going to see the president—and represent Black people in a society that questions Black intelligence. I cried. They cried. It was the most touching thing.
  • I am a reflection of the accumulated wisdom these teachers passed on to me. All of these great teachers who had preceded me, who taught in segregated schools under horrible conditions, with no equal pay.
Dennis OConnor

HCPs finally embrace the patient-reported-data revolution - Features - MM&M - Medical M... - 1 views

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    "While Alperin characterizes the shift in support among HCPs as gradual, he points to the arrival of the Apple Watch - the most recent model adds a feature that measures the saturation of oxygen in the user's blood - as "the biggest point of inflection." He notes that he has confirmed the accuracy of the watch's readings against EKGs performed in his office. And while that firsthand experience may be anecdotal, he believes it offers "one more piece of validation.""
Dennis OConnor

FAQs on Diagnostic Testing for SARS-CoV-2 | FDA - 0 views

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    Explanation from DeAunne Denmark, MD, PhD : And just to clarify for all, since all of the testing jargon and landscape can be *extremely* confusing, especially now: The FDA has currently relaxed regulations for COVID diagnostics under "Emergency Use" (EUA). This authorizes, not approves, test kits, machines and devices to run those kits, and all other aspects involved in diagnostic testing. Authorize vs approve are very different animals under FDA. And you will see this repeatedly emphasized on the FDA site. But most often neglected, skipped over, mistaken in the wider press. Many articles and press releases use "approve" which is technically wrong - they mean authorize, or "grant use", or "use will not be objected to by FDA." If you have the stamina, I highly recommended reading as much of this as you can: https://www.fda.gov/medical-devices/emergency-situations-medical-devices/faqs-diagnostic-testing-sars-cov-2 "Validation" is yet an additional aspect that is probably the grayest zone of all, since it is left to each company/testing entity how exactly this is done. Validation can range from excellent to pretty cruddy science and still meet FDA "standards". These will be the devilish details we need to sort out re: collaborating with partners. And will unfortunately likely be a big mess for many outpatient Drs trying to figure out which test to order.
Dennis OConnor

Poetry of Resilience: From Haiku to Free Verse | San Diego Public Library - 0 views

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    Registration for this event will close on December 11, 2021 @ 4:00pm. There are 8 seats remaining. Event Details This is an in-person event at the San Diego Central Library. Masks are required for unvaccinated patrons and social distancing protocol will be followed. During World War II, heroic San Diego librarian Clara Breed exchanged hundreds of letters with young Japanese Americans in concentration camps, serving as a reminder of the possibility for decency and justice in a troubled world. Join 14 of San Diego's best poets including the City's inaugural Poet Laureate, Ron Salisbury, for an afternoon of restorative poetry. Poets will read and perform poems written specifically for this current historical moment of deep national reflection and a deadly pandemic which has locked down our lives and created isolation and fear.
Dennis OConnor

Visualizing the Long Covid experience | by Katie McCurdy | Jul, 2022 | Medium - 0 views

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    "As a highly allergic and reactive person with multiple autoimmune conditions, I am likely at risk for Long Covid. I've closely followed the news about this mysterious and pervasive new condition and read about its debilitating symptoms. But until now, I hadn't personally known anyone with Long Covid."
Dennis OConnor

First U.S. Company Announces an Upcoming Home COVID-19 Test | Time - 0 views

  • Food and Drug Administration allowed certified labs, including commercial lab testing companies, to develop and distribute COVID-19 tests on Feb. 29.
  • People can order the Everlywell COVID-19 test on the company’s website, after first answering questions about their basic health, symptoms and risk factors for the coronavirus disease. A doctor still needs to prescribe the test, so telemedicine doctors from PWNHealth, a national network of physicians who prescribe diagnostic tests, then reviews these answers to determine if a person qualifies for testing, based on criteria established by the Centers for Disease Control and Prevention.
  • Currently, because COVID-19 tests are not plentiful in the U.S., doctors are trying to rule out other respiratory diseases like flu first, and only ordering tests for people with symptoms who also have other risk factors for infection, such as being in close contact with others who have been diagnosed.
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  • If the telemedicine doctor decides to prescribe an Everlywell COVID-19 test, the company says it will send the $135 test kit in two days (customers can pay $30 more to receive the kit overnight).
  • As with many of the commercially available tests, this one extracts SARS-CoV-2, the virus behind COVID-19, from the sample and then probes for specific genetic signatures of the virus.
  • If the test is positive, the company also provides a full telemedicine consultation with one of around 200 physicians that is included in the cost of the test.
  • Everlywell says it is ready to ship 30,000 COVID-19 tests, and plans to expand the number of labs processing the sample
  • kits will depend on the availability of swabs for collecting samples
  • global shortage of swabs for any lab performing the test.
  • We’re working hard to ramp up weekly capacity to test 250,000 Americans,” says Cheek
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    DeAunne Denmark, M.D. Phd - I was just reading about this last night. Dr forum blowing up about it. It could be a gigantic win for EverlyWell (and at-home D-T-C Direct-to-Consumer) if they do it right. But *must* do it right, e.g. including transparency re: methods, interfacing with HCP/EMRs, etc. The big issue may be collection variability, not unlike the microbiome. Nasal swab not trivial, more talk now about collection variability possibly accounting for a large proportion of "negs" turning positive. Hate to see a lot of false confidence running around at large infecting others.
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