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Research leading to almost every Nobel Prize in Medicine awarded since 1901 was dependent on data from animal models.  This fact dramatically demonstrates the important contribution animal models in biomedical research make to both international and American medical progress. In fact, since 1979, every Nobel Prize in Medicine awarded was dependent on data from animal models with the exception of the 1983 Prize awarded to Dr. Barbara McClintock for her work in plant genetics.

Find out how researchers identify genetic diseases and determine possible treatments. short film, genes as medicine click and learn, central dogma scientists at work, the search for a mutated gene central dogma card activity animation, CF mechanism and treatment click and learn. CRISPR-Cas9

6:45 video animation of types of cell division

A zebrafish model of a rare genetic disease has revealed an unexpected regulatory pathway for cholesterol absorption and processing. The findings, reported in the Journal of Molecular Medicine, were "quite surprising and have the potential to teach us about the basic physiology of cholesterol management," said Ela Knapik, M.D., associate professor of Medicine and Cell and Developmental Biology.

Now eight years old, USAID PREDICT is a collaborative effort to monitor, predict and prevent emerging diseases, many of them zoonotic, from becoming devastating global pandemics the likes of Ebola. It's led by Jonna Mazet, an epidemiologist at the University of California at Davis's One Health Institute and School of Veterinary Medicine, and also partners with the Wildlife Conservation Society, Metabiota, EcoHealth Alliance and the Smithsonian Institution's Global Health Program.

7:26 animation on photosynthesis

Damaged leg muscles grew stronger and showed signs of regeneration in three out of five men whose old injuries were surgically implanted with extracellular matrix derived from pig bladder, according to a new study. Early findings are from a human trial of the process as well as from animal studies.

 Do the principles of the Belmont Report address all the ethical issues that arise in evolving research scenarios? (November, 2013) Watch the full video - http://www.peopleandperspectives.org/... People & Perspectives (P&P) is a digital oral history library supported by Public Responsibility in Medicine & Research (PRIM&R). Visit http://www.peopleandperspectives.org to learn more. P&P features stories of those working in research ethics, many of whom were involved in the early years of the field. Those featured include IRB and IACUC professionals, research staff, committee members, institutional officials, researchers, subjects, advocates, regulators, industry representatives, ethicists, and others who consider themselves part of the human subjects and animal care and use enterprise.

When scientists first made contact with an isolated village of Yanomami hunter-gatherers in the remote mountains of the Amazon jungle of Venezuela in 2009, they marveled at the chance to study the health of people who had never been exposed to Western medicine or diets. But much to their surprise, these Yanomami's gut bacteria have already evolved a diverse array of antibiotic-resistance genes, according to a new study, even though these mountain people had never ingested antibiotics or animals raised with drugs. The find suggests that microbes have long evolved the capability to fight toxins, including antibiotics, and that preventing drug resistance may be harder than scientists thought.

Almost 80% of all antibiotics in the United States aren't taken by people. They're given to cows, pigs, and chickens to make them grow more quickly or as a cheap alternative to keeping them healthy. These drugs could give rise to superbugs-bacteria that can't be treated with modern medicine-and things are only getting worse. In 2013, more than 131,000 tons of antibiotics were used in food animals worldwide; by 2030, it will be more than 200,000 tons. In a paper published today in Science, epidemiologist Thomas Van Boeckel of the Swiss Federal Institute of Technology in Zurich and colleagues outline the growing threat-and what can be done about it. Boeckel spoke to us about his team's work. This interview has been edited for clarity and length.

animation of agglutination

Central dogma article with brief animations

The mouse is a common model used in research as a way of studying human biology and diseases, but a new study questions whether this is an accurate approach considering some stark differences - aside from many similarities - between the two species.

Genetic and biotechnology can improve food security, the environment and public health. Yet dramatic innovation can lead to unintended consequences and present ethical challenges. In theory, the study of genetics and related cutting edge sciences are widely celebrated. But in practice, the words "gene" and "genetic engineering" often stir fear and misunderstanding when applied to biomedicine and farming. Intricate science scares people who don't understand risk and complexity. What is the potential of agricultural and human genetics? The commitment of the GLP is to promote public awareness of genetics and science literacy.