Group items tagged

When a person dies from cancer, the culprit is usually not the original tumor but rather the cancerous cells that spread throughout the body and replicate in distant organs, a process called metastasis. Researchers have long known that metastasizing cancer cells slip their bonds and avoid immune detection by altering the sugars on their surfaces. They've even come up with a would-be drug to prevent such sugar alterations. But that compound interferes with needed sugars on normal cells, too, with lethal results in animals. Now, Dutch researchers report that they've packaged the drug in nanoparticles targeted exclusively to cancer cells, and they've shown that this combination prevents cancer cells from metastasizing in mice.  

When you eat something loaded with sugar, your taste buds, your gut and your brain all take notice. This activation of your reward system is not unlike how bodies process addictive substances such as alcohol or nicotine -- an overload of sugar spikes dopamine levels and leaves you craving more. Nicole Avena explains why sweets and treats should be enjoyed in moderation.

A new study by Duke University researchers helps clarify the matter by showing how a sugar habit changes specific brain circuits, and how those changes produce cravings that reinforce the habit. The research team began by getting a group of healthy mice hooked on sugar. Similar to classic studies on drug addiction, the mice in this study were trained to press a tiny lever to receive doses of sweets. Once the mice were hooked, they continued pressing the lever even when the sweets were removed. So that was step one, establishing a behavioral pattern to get the goods.

"When you are diabetic, you have to check your blood sugar levels. The doctor tells you to do it four times a day. So you prick your finger. A tiny drop of blood appears. You put it on the tester and within five seconds you get the result," says Timothée, who suffers from diabetes. Normally, it's the job of the pancreas to control the levels of sugar in the blood by producing a hormone called insulin.

You've always been told sugar is bad for you, but how bad is it really? Find out in this science music video - researched, written, sung, directed, shot, and edited by 8th graders from The Nueva School in California. This song is a science parody of "Sunday Candy" by Donnie Trumpet & The Social Experiment, featuring Chance the Rapper and Jamila Woods.

Six years ago, Yale University's Stephen Stearns and colleagues took advantage of a long-running study in Framingham, Massachusetts, to assess whether the effects of natural selection could be discerned among the people in the multigenerational study population. Over the last seven decades, public-health researchers have been monitoring the residents of Framingham, noting their vital statistics as well as blood sugar and cholesterol levels to understand the factors that lead to heart disease. As the initial group of research subjects got older, the study started to include their children, and then their grandchildren. The records provide a unique view of the health of a segment of the American population since 1948.

5:37 video A hearty bowl of cereal gives you the energy to start your day, but how exactly did that energy make its way into your bowl? It all begins with photosynthesis, the process that converts the air we breathe into energizing glucose. Cathy Symington details the highly efficient second phase of photosynthesis -- called the Calvin cycle -- which converts carbon dioxide into sugar with some clever mix-and-match math.

Each person in the United States generates five or more pounds (2.3 kilograms) of waste a day: about the weight of a medium bag of sugar. More than half of that garbage is buried and stored in landfills. Increasingly, however, cities are promoting recycling programs, often getting schools involved so students can learn about recycling and follow these practices at home. A person in a Scandinavian country (such as Sweden, Denmark, or Norway) generates about the same amount of waste as an American. People in developing countries generate less waste than Americans or Europeans; for example, a person in India generates about three-fourths of a pound (0.34 kilograms) per day. Still, every country must find a way to process the garbage that each of its residents generates every day, month, and year.

Published on Feb 19, 2015 View full lesson: http://ed.ted.com/lessons/what-does-t... Beneath your ribs, you'll find, among other things, the pancreas -- an organ that works a lot like a personal health coach. Emma Bryce explains how this organ controls your sugar levels and produces a special juice that releases the nutrients from your food to help keep you in the best possible shape. Lesson by Emma Bryce, animation by Tremendousness.

Cancer cells are hungry. To feed their rapid growth and division, their metabolism changes. Moreover, they use sugar (glucose) in a different way to normal cells. This animation, created by Nature Reviews Drug Discovery, explores the key aspects of the altered metabolism in cancer cells and explains how these can be exploited for the development of new anticancer strategies.

Where does bread get its fluffiness? Swiss cheese its holes? And what makes vinegar so sour? These foods may taste completely different, but all of these phenomena come from microorganisms chowing down on sugar and belching up some culinary byproducts. Erez Garty shows how your kitchen functions as a sort of biotechnology lab, manned by microorganisms that culture your cuisine.

2:30 video A video from the Centers for Disease Control and Prevention offering information on the basics of diabetes.

The study is the first to examine all of the gene networks affected by fructose that result in changes to brain function and metabolism-more than 20,000 genes in total. Although the study was conducted using rats, the researchers report that the majority of the sequenced genes are comparable to those in humans, including more than 200 genes in the hippocampus, a brain area crucial to memory, and 700 in the hypothalamus, the seat of the brain's metabolic control center.