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Lottie Peppers

Should research animals be named? | Science/AAAS | News - 0 views

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    Scientists once shied away from naming research animals, and many of the millions of mice and rats used in U.S. research today go nameless, except for special individuals. But a look at ​many facilities suggests that most of the ​other ​891,161 ​U.S. ​research animals ​have proper names​, including nonhuman primates, dogs, pigs, rabbits, cats, and sheep​.
Lottie Peppers

How the Vitamins Got Their Names - YouTube - 0 views

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    4:47 video   The list of vitamins can be kind of confusing, what with all those B vitamins and a random K thrown in. But every name has its story.
Lottie Peppers

Elephants: Large, Long-Living and Less Prone to Cancer - The New York Times - 0 views

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    In 1977, a University of Oxford statistician named Richard Peto pointed out a simple yet puzzling biological fact: We humans should have a lot more cancer than mice, but we don't. Dr. Peto's argument was beguilingly simple. Every time a cell divides, there's a small chance it will gain a mutation that speeds its growth. Cells that accumulate several of these mutations may become cancerous. The bigger an animal is, the more cells it has, and the longer an animal lives, the more times its cells divide. We humans undergo about 10,000 times as many cell divisions as mice - and thus should be far more likely to get cancer.
Lottie Peppers

New Ways to Breathe - National Center for Case Study Teaching in Science - 0 views

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    This case study follows a young cystic fibrosis (CF) patient named Lucas. Through Lucas's story and interactions between his parents and pediatrician, students learn about the scientific background and basis of CF. By reviewing email correspondence between Lucas's parents and various doctors, students gain an overview of CF research. CF has become a model disease in certain undergraduate biology classrooms due to its relatively clear mechanism and genetic basis. This case asks students to come up with their own ideas to improve on an existing line of research - gene therapy - in treating CF. During the process, students will gain a better appreciation of the innovative nature of science and develop research skills such as finding, understanding and analyzing primary literature. The activity was originally designed for first- and second-year students as part of an extracurricular case competition, but may be used for any undergraduate biology level. The case assumes basic (high school level) knowledge of genetics, biochemistry, cell biology and physiology.
Lottie Peppers

Classic Experiments in Molecular Biology - National Center for Case Study Teaching in S... - 0 views

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    All introductory biology textbooks, and many sophomore-level genetics textbooks as well, describe several classic experiments in molecular biology. This interrupted case study takes students through two of these classic experiments, namely, those by Griffith and Avery, McCarty and MacLeod that showed DNA to be the genetic material in Streptococcus pneumoniae, and the experiment by Meselson and Stahl that demonstrated DNA replication to be semiconservative. Engaging students with the experiments in a more exploratory manner can reinforce the nature of scientific discovery and the logic behind these findings. The case, which has been formatted as two separate exercises that can be used independently, was developed for use in introductory biology classes for biology majors. The material is accessible enough to also be useful for non-majors college biology or high school AP biology students.
Lottie Peppers

CRACKING THE CODE/CLONING PAPER PLASMID - 0 views

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    "CRACKING THE CODE"/"Cloning Paper Plasmid" activities can (1) serve as a review of the "genetic code" and the role it plays in our life; and, (2) to help students see how genes may be manipulated for genetic research, namely, gene cloning/genetic engineering. The laboratory time, the specialized equipment and expertise to carry out recombinant DNA experiments may be lacking in the high school. Activity 2 will help students conceptualize the mechanics involved in cutting and ligating DNAs into a plasmid vector with "sticky ends" of complementary DNA base pairs.
Lottie Peppers

Our stone tool discovery pushes back the archaeological record by 700,000 years - 0 views

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    We, and the West Turkana Archaeological Project which we co-lead, had discovered the earliest stone artifacts yet found, dating to 3.3 million years ago. The discovery of the site, named Lomekwi 3, instantly pushed back the beginning of the archaeological record by 700,000 years. That's over a quarter of humanity's previously known material cultural history.
Lottie Peppers

Evolution Resources from the National Academies - 0 views

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    Have you ever wondered why people look the way they do? Why our hands and feet have five digits instead of six? Why we stand on two legs instead of four? It took 350 million years of evolution to produce the amazing machine we call the human body and in Your Inner Fish, a three-part series based on the best-selling book of the same name, author and evolutionary biologist Dr. Neil Shubin looks into the past to answer these and other questions.
Lottie Peppers

Steve Silberman: The forgotten history of autism - YouTube - 0 views

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    Decades ago, few pediatricians had heard of autism. In 1975, 1 in 5,000 kids was estimated to have it. Today, 1 in 68 is on the autism spectrum. What caused this steep rise? Steve Silberman points to "a perfect storm of autism awareness" - a pair of doctors with an accepting view, an unexpected pop culture moment and a new clinical test. But to really understand, we have to go back further to an Austrian doctor by the name of Hans Asperger, who published a pioneering paper in 1944. Because it was buried in time, autism has been shrouded in misunderstanding ever since. (This talk was part of a TED2015 session curated by Pop-Up Magazine: popupmagazine.com or @popupmag on Twitter.)
Lottie Peppers

Frances Oldham Kelsey, F.D.A. Stickler Who Saved U.S. Babies From Thalidomide, Dies at ... - 0 views

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    Thus began a fateful test of wills. Merrell responded. Dr. Kelsey wanted more. Merrell complained to Dr. Kelsey's bosses, calling her a petty bureaucrat. She persisted. On it went. But by late 1961, the terrible evidence was pouring in. The drug - better known by its generic name, thalidomide - was causing thousands of babies in Europe, Britain, Canada and the Middle East to be born with flipperlike arms and legs and other defects.
Lottie Peppers

Drug Wars: An Epic Tale of Asthma and Bacterial Pneumonia - National Center for Case St... - 0 views

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    This integrative case study is based on real events that the author experienced with her ten-year-old daughter. Although the names have been changed, all of the events (symptoms, diagnoses and treatments, types of healthcare professionals) are recorded exactly as they occurred. Both asthma and pneumonia are common in the United States (and globally). Many of the drugs described in the case study are frequently prescribed for a wide variety of ailments. The four "episodes" that constitute the case cover 1) a study of asthma triggers, incidence and treatment; 2) side effects and possible medication errors associated with steroids; 3) causes, diagnosis, treatment and prevention of community-acquired bacterial pneumonia; and 4) the mechanism of action of two different antibiotics. The "epilogue" explores a few larger themes related to healthcare and public health (e.g., continuity of care, drug resistance, asthma prevention programs). The case study could be used in an undergraduate, upper-level, infectious disease, microbiology, public health or physiology course or in a graduate-level health professions program.
Lottie Peppers

Treated mosquito nets may have created an insecticide resistant mosquito | The Verge - 0 views

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    Malaria has long been a problem in Mali. But in 2006, the situation got worse: a malaria-carrying mosquito species named Anopheles coluzzii became increasingly resistant to common insecticides. Scientists searched for an explanation in its genes. Somehow, the species had acquired mutations that were previously only found in another species, Anopheles gambiae - despite the fact that these two species didn't usually mate with each other, and that their hybrids tended to die without producing offspring of their own, the mutations were identical.
Lottie Peppers

Pompe Disease | Patients & Families: Living with Pompe Disease >> Pompe Perspectives - 0 views

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    Meet five fellow Pompe patients as they recount their own experiences with the diagnostic journey. You are sure to find bits of your own story in theirs. The road to diagnosis can be riddled with uncertainty, an array of specialists all looking for an answer, and even misdiagnosis. That is undoubtedly why many people living with Pompe welcome the moment a physician delivers the correct diagnosis. Finally, an answer; a name for what has been happening all these years.
Lottie Peppers

About OpenBiome - OpenBiome - 0 views

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    OpenBiome (full name Microbiome Health Research Institute Inc.) is a nonprofit organization dedicated to expanding safe access to fecal microbiota transplantation (FMT) therapies. Founded by a small team of microbiologists, public health advocates, and concerned citizens, OpenBiome aims to significantly reduce the practical barriers for clinicians providing FMTs, while connecting scientists across studies and disciplines. 
Lottie Peppers

Dichotomous Keys: Identification Achievement Unlocked - YouTube - 1 views

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    Join the Amoeba Sisters in discovering how to use a dichotomous key to identify organisms. This video also touches on the importance of scientific names.
Lottie Peppers

The untreatable Zika virus just made its way into another US territory - and it's not l... - 0 views

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    The CDC released travel health notices Tuesday that named two more places in which the disease has spread via mosquito bites: The US Virgin Islands and the Dominican Republic.  The Zika virus is primarily transmitted by Aedes aegypti, the type of mosquito responsible for spreading dengue, yellow fever, and a whole host of other tropical infectious diseases. Originally identified in 1947 in Uganda, Zika was relatively unknown until 2007, when there was an outbreak of the virus in Micronesia. The mosquitoes pick up the virus from infected people, according to the CDC. 
Lottie Peppers

The Making of the Fittest: Natural Selection in Humans | HHMI's BioInteractive - 1 views

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    A keenly observant young man named Tony Allison, working in East Africa in the 1950s, first noticed the connection and assembled the pieces of the puzzle. His story stands as the first and one of the best understood examples of natural selection, where the selective agent, adaptive mutation, and molecule involved are known-and this is in humans to boot. The protection against malaria by the sickle-cell mutation shows how evolution does not necessarily result in the best solution imaginable but proceeds by whatever means are available.
Lottie Peppers

Forensics gone wrong: When DNA snares the innocent | Science | AAAS - 0 views

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    Its accuracy has made DNA evidence virtually unassailable. A landmark report published by the National Research Council in 2009 dismissed most forensics as unproven folk-wisdom but singled out DNA as the one forensic science worthy of the name. Yet in recent years Hampikian and other geneticists have begun to question the technology. Thanks to a series of advances-including the polymerase chain reaction, which can multiply tiny amounts of DNA-it's now possible to detect DNA at levels hundreds or even thousands of times lower than when DNA fingerprinting was developed in the 1980s. Investigators can even collect "touch DNA" from fingerprints on, say, a glass or a doorknob. A mere 25 or 30 cells will sometimes suffice. This heightened sensitivity can easily create false positives
Lottie Peppers

CSPI: There are concerns about GMOs, but not around food safety - 0 views

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    The Center for Science in the Public Interest (CSPI) has made a name for itself by tackling the food industry's big guns on everything from artery-furring entrees to misleading label claims. But where does it stand on genetically modified organisms (GMOs)? Elaine Watson quizzed Gregory Jaffe, CSPI director of biotechnology, on everything from GM labeling initiatives to super weeds…
Lottie Peppers

Absurd Creature of the Week: The Octopus That Does Incredible Impressions of Fish and S... - 0 views

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    And no copycat is stranger or more accomplished than the mimic octopus. True to its name, it impersonates a variety of other animals on the fly, morphing from an octopus to a banded sole to a lionfish to a sea snake. But this is no random assemblage of impressions: All of these creatures are toxic or venomous.
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