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This animated short film tells the engaging tale of the discovery of the coelacanth. In 1938, South African museum curator Marjorie Courtenay-Latimer came across a strange blue fin poking out of a pile of fish. With its fleshy, lobed fins and its tough armored scales, the coelacanth did not look like any other fish that exists today. The coelacanth belongs to a lineage that has remained virtually unchanged for hundreds of millions of years-earning it the description of a "living fossil."

But then on Dec. 22, 1938, Marjorie Courtenay-Latimer came across a strange blue fin poking out of a pile of fish that struck her as extraordinary. With its fleshy, lobed fins and its tough armored scales, the specimen looked very unlike fish we see in our oceans today. That is because the coelacanth has managed to survive in roughly its current form for hundreds of millions of years. In the course of researching this film, we learned all kinds of amazing facts about the coelacanth. For instance, unlike most fish, they give birth to live young. They produce eggs the size of grapefruits, which then hatch internally. From video footage taken by the explorer Hans Fricke - which we used as inspiration for our sets and puppets - we know coelacanths are prone to some odd behavior. They've been spotted doing headstands underwater.

1:30 A short film about DNA microarrays, and how they are used to show dynamic gene expression levels.

Hilary Brown is a PhD student, working in the infection genomics group at the Wellcome Trust Sanger Institute. In this film he describes how to work safely in the lab with bacteria from the human gut including culturing them on agar plates and extracting the DNA for genome sequencing. The infection genomics programme uses a variety of different research approaches to study the biology and evolution of disease-causing organisms such as viruses, bacteria and parasites and understand how they cause disease in humans and other animals.

In this activity, students build a paper model of DNA and use their model to explore key structural features of the DNA double helix. This activity can be used to complement the short film The Double Helix.

30 day free trial available for 3 minute videos

Penn State University anthropologist Dr. Nina Jablonski walks us through the evidence that the different shades of skin color among human populations arose as adaptations to the intensity of ultraviolet radiation in different parts of the world.

In 1674, Antonie van Leeuwenhoek looked at a drop of lake water through his homemade microscope and discovered an invisible world that no one knew existed. His work inspired countless microbiology researchers, including HHMI investigator Bonnie Bassler, one of the narrators of this animated feature. Leeuwenhoek was a haberdasher and city official in Delft, The Netherlands. He started making simple microscopes and using them to observe the world around him. He was the first to discover bacteria, protists, sperm cells, blood cells, rotifers, and much more. 

15 minute video

10 min video, documentary on bacteria using classic footage

A keenly observant young man named Tony Allison, working in East Africa in the 1950s, first noticed the connection and assembled the pieces of the puzzle. His story stands as the first and one of the best understood examples of natural selection, where the selective agent, adaptive mutation, and molecule involved are known-and this is in humans to boot. The protection against malaria by the sickle-cell mutation shows how evolution does not necessarily result in the best solution imaginable but proceeds by whatever means are available.

This two-hour special, hosted by ABC "Nightline" correspondent Robert Krulwich, chronicles the fiercely competitive race to capture one of the biggest scientific prizes ever: the complete letter-by-letter sequence of genetic information that defines human life-the human genome. NOVA tells the story of the genome triumph and its profound implications for medicine and human health.