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4:13 Bowerbirds with David Attenborough

4 min We tend to think of blindness as something you're born with, but with certain genetic diseases, it can actually develop when you're a kid, or even when you're an adult. But could blind eyes possibly regenerate? David Davila explains how the zebrafish's amazing regenerative retinas are causing scientists to investigate that very question.

Watch this video (6:30), play with the interactive version of the 'Tree of Life' and sign up to Tree of Life updates at http://www.wellcometreeoflife.org. This six-minute Tree of Life video appeared on the BBC One programme 'Charles Darwin and the Tree of Life' narrated by David Attenborough.

After the third time he nearly died but before the fourth, David Fajgenbaum embraced a new motto: Think it, do it. "I got out of the hospital with this profound sense of, you need to make the most of every second," he says. A former college football player with close-cropped dark hair and a firm handshake, Fajgenbaum, 31, is the picture of youthful vigor now. But that belies a frightening reality. Tomorrow the symptoms with which he's all too familiar could return, sending him to the intensive care unit (ICU) with every organ failing. 

The fates of ice age human groups in Europe were closely linked to climate change, according to an unprecedented study of the genomes of 51 individuals who lived between 45,000 years ago (when modern humans arrived in Europe) and 7,000 years ago. "We see multiple, huge movements of people displacing previous ones," David Reich of the Harvard Medical School said. "During this first four-fifths of modern human history in Europe, history is just as complicated as it is during the last fifth that we know so much more about." 

From the following article: The velocity of climate change Scott R. Loarie, Philip B. Duffy, Healy Hamilton, Gregory P. Asner, Christopher B. Field & David D. Ackerly Nature 462, 1052-1055(24 December 2009) doi:10.1038/nature08649

Part 2 of 2. David Attenborough explains how early sea life developed and adapted to dry land, becoming Reptiles and Amphibians. After the era of the Dinosaurs came to a sudden end, Mammal species began to proliferate. From BBC 1 documentary 'Charles Darwin and the Tree of Life'.

If we learned anything from the David and Goliath legend, it's that underdogs can win, right? On this edition of Up To Date, journalist, author and critical thinker Malcolm Gladwell speaks with Steve Kraske about the traditional understandings of the weak and the powerful. Plus, the advantages of thinking outside the box. 

However, new research led by Michigan State University psychology professor David Z. Hambrick suggests that, unfortunately for many of us, success isn't exclusively a product of determination - that despite even the most hermitic practice routine, our genes might still leave greatness out of reach.

More than 400 scientists, bioethicists, and historians from 20 countries on 6 continents have gathered this week in Washington, DC, for the Human Gene Editing Summit. The attendees are a veritable who's who of genome editing: Jennifer Doudna of the University of California, Berkeley, Emmanuelle Charpentier of Max Planck Institute for Infection Biology, and Feng Zhang of the Broad Institute of MIT and Harvard-the three discoverers of the CRISPR-Cas9 system's utility in gene editing-plus dozens of other big names in genome science. Cal Tech's David Baltimore along with the heads of the four national societies hosting the meeting (US National Academy of Sciences, US National Academy of Medicine, Chinese Academy of Sciences, and the U.K.'s Royal Society) provided opening remarks on Tuesday (December 1). And as I sat stage right in the NAS auditorium, I noticed the unmistakable rear profile of Harvard Medical School's George Church three rows in front of me. Church was scheduled to speak at a session later that afternoon about the application of CRISPR and other new precision gene editing techniques to the human germline-a hot-button topic since April, when a Chinese group published it had successfully modified the genomes of human embryos, and the National Institutes of Health (NIH) said it would not fund such research. Then in September, the U.S./U.K.-based Hinxton Group, an international consortium of scientists, policy experts, and bioethicists, said it supported the use of genetic editing in human embryos for limited applications in research and medicine.  

"The brain thrives on a fat-rich, low carbohydrate diet, which unfortunately is relatively uncommon in human populations today," reports David Perlmutter, author of Grain Brain. "Mayo Clinic researchers showed that individuals favoring carbohydrates in their diets had a remarkable 89 percent increased risk for developing dementia as contrasted to those whose diets contained the most fat. Having the highest levels of fat consumption was actually found to be associated with an incredible 44 percent reduction in risk for developing dementia."

The mystery of where these orphan genes came from has puzzled scientists for decades. But in the past few years, a once-heretical explanation has quickly gained momentum - that many of these orphans arose out of so-called junk DNA, or non-coding DNA, the mysterious stretches of DNA between genes. "Genetic function somehow springs into existence," said David Begun, a biologist at the University of California, Davis.