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Find out how researchers identify genetic diseases and determine possible treatments. short film, genes as medicine click and learn, central dogma scientists at work, the search for a mutated gene central dogma card activity animation, CF mechanism and treatment click and learn. CRISPR-Cas9

2:32 DNA replication animation

activities complementing 15 minute video about evolution and natural selection in stickleback fishes

Humans construct boundaries -- around our homes, our neighborhoods, and our nations -- to bring order to a chaotic world. But we rarely consider how these boundaries affect other creatures. In this episode of Think Like A Scientist, we meet conservation photographer Krista Schlyer, who has spent the last seven years documenting the environmental effects of the U.S./Mexico border wall, and biologist Jon Beckmann, who studies how man-made barriers influence the movement of wildlife. Schlyer and Beckmann have seen damaging impacts of the border wall firsthand, but they remain optimistic. Humans probably won't stop constructing walls and fences any time soon, but planning our boundaries with wildlife in mind can help prevent these structures from causing environmental harm.

A mini-documentary discussing the remarkable regenerative capabilities of the planarian, and how HHMI researcher Alejandro Sánchez Alvarado uses them to study the biology of stem cells.

All adult mammals but humans are lactose intolerant. Follow human geneticist Spencer Wells, director of the Genographic Project of the National Geographic Society, as he tracks down the genetic and societal changes associated with the ability to digest lactose as adults-or lactose tolerance.

Interactive exploration that challenges you to determine whether an athlete is qualified to compete as a female. Along the way you may gain some understanding of the biology of sex and in particular how sex is determined in humans. nteractive exploration that challenges you to determine whether an athlete is qualified to compete as a female. Along the way you may gain some understanding of the biology of sex and in particular how sex is determined in humans.

The structure of DNA, discovered by James Watson and Francis Crick, suggests a mechanism of replication. The double helix unwinds, and each strand acts as a template for the construction of the new DNA molecule.

All living humans originated from populations of ancestors who migrated out of Africa less than 100,000 years ago. Learn how scientists have used genetic markers to trace the migration routes and origins of modern human populations.

In 1674, Antonie van Leeuwenhoek looked at a drop of lake water through his homemade microscope and discovered an invisible world that no one knew existed. His work inspired countless microbiology researchers, including HHMI investigator Bonnie Bassler, one of the narrators of this animated feature. Leeuwenhoek was a haberdasher and city official in Delft, The Netherlands. He started making simple microscopes and using them to observe the world around him. He was the first to discover bacteria, protists, sperm cells, blood cells, rotifers, and much more. 

3:32 video Narrated by anthropologist Nina Jablonski, this engaging animation shows how human skin cells produce the pigment melanin, which gives skin its color.

This animated short video tells the story of Alfred Russel Wallace, who independently formulated the theory of evolution by natural selection at the same time as Charles Darwin.Co-directed by Flora Lichtman and Sharon Shattuck of Sweet Fern Production, the video tracks A. R. Wallace's life from growing up in England to his voyages with Henry Walter Bates and later adventures in the Malay Archipelago. The 8-minute video ends with an examination of the naturalist's legacy. (The video is presented here with permission from Sweet Fern Productions.)

15 minute video

This hands-on activity, used in conjunction with the film The Making of the Fittest: Natural Selection in Humans, teaches students about population genetics, the Hardy-Weinberg principle, and how natural selection alters the frequency distribution of heritable traits. It uses simple simulations to illustrate these complex concepts and includes exercises such as calculating allele and genotype frequencies, graphing and interpretation of data, and designing experiments to reinforce key concepts in population genetics.

Virtual lab activities 

Dr. Richard Lifton, along with student volunteers, uses an aquarium and salt to illustrate the amount of work the kidney performs each day to maintain proper levels of ions in the body.

This activity can be used in conjunction with the short film The Double Helix. It introduces students to the classic experiment by Matthew Meselson and Franklin Stahl, which revealed that DNA replication follows the semiconservative model.

Cone snail background 2 minute video

In the second film of the Great Transitions trilogy, paleontologist Julia Clarke takes us on a journey to uncover the evidence that birds descended from dinosaurs. The discovery of Archaeopteryx in a quarry in Germany in the early 1860s provided the first clue that birds descended from reptiles. But what kind of reptile? In the last 40 years, scientists have identified many shared features between birds and two-legged carnivorous dinosaurs called theropods. The film illustrates many of the practices of science, including asking important questions, formulating and testing hypotheses, analyzing and interpreting evidence, and revising explanations as new evidence becomes available.