A great list of "first things first" checks for any organization with a web site.... addresses many common frustrations that users with disabilities have when surfing the Web.
A writer who suffers a stroke loses the ability to read by sight, but adapts his ability to read via motor cues to not only learn to read again, but to produce another book.
"People who are completely paralyzed due to illness or trauma are getting help communicating with a new technology that connects their brains to a computer."