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Pursuant to the Foreign Assistance Act of 1961, as amended (FAA), the United States Agency for International Development (USAID) requests applications from qualified and eligible organizations to manage and implement the TRANSFORM/PRIMARY HEALTH CARE UNIT (PHCU) as described in Section I of this RFA. The overall goal of the program is to support the Government of Ethiopia (GOE) through the implementation of its new Health Sector Transformation Plan (HSTP) to End Preventable Child and Maternal Deaths (EPCMD). This RFA is issued in accordance with the Foreign Assistance Act of 1961, as amended, and the Grants and Cooperative Agreement Act of 1977. This is a full and open competition, under which any type of organization, large or small, commercial (for profit) firms, faith-based, and non-profit organizations in partnerships or consortia from geographical code 935, are eligible to compete. In accordance with the Federal Grants and Cooperative Agreement Act, USAID encourages competition in order to identify and fund the best possible applications to achieve its program objectives. While for-profit firms may participate, pursuant to 22 CFR 226.81, it is USAID policy not to award profit under assistance instruments such as cooperative agreements. However, all reasonable, allocable, and allowable expenses, both direct and indirect, which are related to the grant program and are in accordance with applicable cost standards (22 CFR 226, OMB Circular A-122 for non-profit organization, OMB Circular A-21 for universities, and the Federal Acquisition Regulation (FAR) Part 31 for-profit organizations), may be paid under the Cooperative Agreement. Using a "Design and Implement" approach, USAID anticipates issuing one mission-specific Leader Award under a Leader with Associates (LWA) arrangement. An LWA arrangement involves the issuance of a grant or cooperative agreement ("Leader Award") that covers a specified regional activity. The Leader Award includes language that all

HEALTH OUTCOMES RESEARCH: Outcomes research spans a broad spectrum of issues from studies evaluating the effectiveness of a particular pharmaceutical intervention to the impact of reimbursement policies on the outcomes of care. It also ranges from the development and use of tools to perform patient-based assessments to analyses of the best way to disseminate the results of outcomes research to providers or consumers to encourage behavior change. Outcomes research incorporates a variety of research methods from various disciplines. The application of outcomes research principles in evaluating the design, delivery, and effectiveness of pharmaceuticals includes the following general areas: * Burden of Disease * Comparative Effectiveness Research * Compliance/Adherence * Cost Consequences Analysis * Cost-Benefit Analysis * Cost-Effectiveness Analysis * Cost Utility Analysis * Patient Satisfaction * Patient Preferences * Psychometric Evaluation of Questionnaires (e.g. reliability, validity, etc.)

Issuance Date: 3 February, 2015RFA Clarification Questions Due: 19 February, 2015; 1600 Closing Date and Time for Application Submission: 12 March, 2015; 1600 Addis Ababa Local Time Subject: Request for Applications (RFA) Number: USAID-Ethiopia- RFA-663-15-000006 RFA Title: Social and Behavior Change Communication for Health (SBCC- Health Project) EthiopiaLadies and Gentlemen: The United States Agency for International Development (USAID) is seeking applications for Assistance Agreements from all U.S. and non-U.S. qualified organizations (other than those from foreign policy restricted countries) for funding to support a program entitled Social and Behavior Change Communication for Health (SBCC- Health Project) Ethiopia. The overall goal of the program is to build the capacity of Federal Ministry of Health (FMoH) with regards to SBCC interventions while also developing effective messages and coordinating SBCC messaging across stakeholders. The authority for the RFA is found in the Foreign Assistance Act of 1961, as amended, and the Grants and Cooperative Agreement Act of 1977. While for-profit firms may participate, pursuant to 22 CFR 226.81, it is USAID policy not to award profit under assistance instruments such as cooperative agreements. However, all reasonable, allocable, and allowable expenses, both direct and indirect, which are related to the grant program and are in accordance with applicable cost standards (22 CFR 226, OMB Circular A-122 for non-profit organization, OMB Circular A-21 for universities, and the Federal Acquisition Regulation (FAR) Part 31 for-profit organizations), may be paid under the Cooperative Agreement.USAID expects to award one Cooperative Agreement based on this RFA. Subject to the availability of funds, USAID intends to allocate approximately $22.2 million funding to be allocated over a Five (5) year period. USAID reserves the right to fund any or none of the applications submitted.The Government of Ethiopia laws require prior regist

Three types of research project are solicited. Projects 1 and 2: Congress has provided funding that will allow HUD to evaluate the efficacy of its resilience expenditures. HUD is soliciting proposals to conduct two distinct, but related, research studies: (1) a cost-effectiveness evaluation that investigates long- and short-term benefits and costs of expenditures designed to reduce risk to people and property from flood hazards and increase resilience to flood impacts, with explicit focus on impacts to vulnerable populations, and (2) an assessment of implementation of flood resilience strategies, with a goal of identifying those implementation practices that have the greatest chance of being successful across a range of communities. Following on each study - the cost-effectiveness analysis and the implementation study - the respective research organization(s) will produce guidance tools for communities carrying out flood resilience strategies. The cost-effectiveness guidance will include practical methods of project assessment that can be deployed by local communities and states with varying levels of capacity for assessing the benefits of resilience expenditures. Implementation guidance will include assessment of common implementation challenges and solutions and best practices for conceiving, planning, funding, and implementing flood resilience strategies, especially how to improve community participation and support of such strategies. For Project 3, HUD is funding co-operative agreements for pre-competitive research in homebuilding technologies that provide the homebuilding industry with new, innovative construction products or practices that lead to more affordable, energy efficient, resilient (in this sense, durable, disaster resistant, adaptable for future requirements, and maintainable), and healthier housing.

To that end, grants of up to $400,000 over up to two years will be awarded in support of promising approaches designed to help create a higher value healthcare system. The proposed research should be focused on developing actionable solutions to one or more of the symptoms of low value health care: high and rising healthcare costs; unwarranted variation in prices; unaffordable cost of care burden on patients and families; unacceptable variation in quality; and/or lack of transparency in both price and outcomes. Eligible approaches include models of care, coverage, or system change that seek to improve value by addressing one or more of the symptoms of low value and/or reduce routine treatments, tests, and screenings for patients for whom the potential harms (including financial harm) outweigh potential benefits; provide tools to help consumers make decisions about their healthcare based on value, including the cost of care to patients (in addition to other patient-centered factors); promote conversations between patients and their clinicians and care teams about preferences and trade-offs related to alternative treatment options and /or out of pocket cost burden to patients and families; and/or test interventions geared to reducing racial and ethnic disparities through the provision of higher value healthcare.

The objectives of this research are to 1. Define and quantify the health and safety issues facing public transit workers. These include, but are not limited to, behaviors that affect health and safety (sleep, exercise, diet, smoking, seat belt use, alcohol use), chronic diseases (diabetes, cardio-vascular disease, hearing loss), communicable diseases, labor environment, organizational issues (safety climate, organizational programs, policies and procedures, support at work), organization of work (shiftwork, job discretion, job demands), and access to health-promoting activities and healthcare; 2. Using existing information resources, estimate the costs associated with employee health issues; and characterize to the degree possible how these costs are distributed to individuals, transit agencies, and society; 3. Identify and describe scalable and sustainable strategies successfully implemented in transit agencies; and 4. Identify and evaluate potential methods for measuring cost-benefits and cost-effectiveness of these programs to individuals, transit agencies, and society.

Woman to Woman, a program of the Ovarian Cancer Research Fund Alliance, pairs gynecologic cancer patients with trained survivor-volunteers who provide one-on-one emotional support and mentoring to women when they need it most. From the moment of diagnosis through the end of treatment, Woman to Woman survivor-volunteers have helped hundreds of women and their families cope with gynecologic cancer. Through the program, one-year grants of either $60,000 (for hospital-based programs) or $30,000 (for community-based organizations) will be awarded to institutions with a large volume of gynecologic cancer patients and a need to provide this type of support to patients. Grants are provided to cover the cost of a part-time program coordinator's salary (can be a new hire or a reassignment), program costs, and a patient fund (no indirect costs allowed). It is expected that each Woman to Woman program will become self-sustaining after the first year. OCRFA will provide all program materials for patients, as well as technical assistance and support, for the life of the program (even after the end of the grant period). Institutions and organizations also will have access to a dedicated section of the Woman to Woman website (under construction) featuring tools designed to assist them in the development and administration of new programs.

Applications are invited in two categories: SFARI Pilot Awards and SFARI Research Awards. 1) SFARI Pilot Awards: Grants are awarded to innovative, high-impact proposals requesting support for small-scale projects or early-stage experiments designed to build on preliminary data or a prior track record and lead to competitive applications for funding by SFARI or other organizations. Investigators new to the field of autism are encouraged to apply. The maximum budget is $150,000 (including indirect costs) per year for up to two years. 2) SFARI Research Awards: Grants awarded through this category are designed for investigators with demonstrated expertise conducting compelling high-impact research on an experimental hypothesis for which, in most cases, preliminary data has already been gathered. The foundation also will consider projects focused on a central hypothesis where success depends on close collaboration between two or more labs. The initiative expects to fund proposals for a maximum of $275,000 per year (including indirect costs) for up to three years, but under exceptional circumstances will consider proposals at higher funding levels.

Applications are invited in two categories: SFARI Pilot Awards and SFARI Research Awards. 1) SFARI Pilot Awards: Grants are awarded to innovative, high-impact proposals requesting support for small-scale projects or early-stage experiments designed to build on preliminary data or a prior track record and lead to competitive applications for funding by SFARI or other organizations. Investigators new to the field of autism are encouraged to apply. The maximum budget is $150,000 (including indirect costs) per year for up to two years. 2) SFARI Research Awards: Grants awarded through this category are designed for investigators with demonstrated expertise conducting compelling high-impact research on an experimental hypothesis for which, in most cases, preliminary data has already been gathered. The foundation also will consider projects focused on a central hypothesis where success depends on close collaboration between two or more labs. The initiative expects to fund proposals for a maximum of $275,000 per year (including indirect costs) for up to three years, but under exceptional circumstances will consider proposals at higher funding levels.

This notice solicits applications for Advancing Systems of Services for Children and Youth with Special Health Care Needs. The purpose of this program is to improve health and well-being for children and youth with special health care needs (CYSHCN) and their families by addressing three core systems focus areas for CYSHCN-access to patient/family-centered medical home, transition of youth into the adult health care system, and adoption of health care financing models that improve care and outcomes while achieving cost savings. This program will establish a national collaborative network of resource centers supporting state Title V programs, families of CYSHCN, child health professionals, and other stakeholders through the provision of technical assistance, training, education, partnership building, policy analysis, and research. Program Goal: The overall goal of this program is to strengthen the system of services for CYSHCN and their families by awarding three separate and distinct cooperative agreements. Cooperative agreements will be awarded to three recipients, who will collaborate to establish a national network of resource centers, with one center awarded for each of the following three focus areas: (1) Patient/family-centered medical home; (2) Transition of youth into the adult health care system; and (3) Health care financing models that improve care and outcomes while achieving cost savings. The three recipients will coordinate efforts to achieve quality care, decrease health care costs, and improve experience of care for CYSHCN and their families. An applicant can apply and be awarded only one focus area. For specific information about applying for one focus area, see Section IV. Application and Submission Information, Project Abstract.

The purpose of this funding opportunity is to incorporate social outcomes (quality of life, untreated pain, etc.) and cost effectiveness into FDA's existing model and policy analysis tool. Work resulting from this funding opportunity should provide more holistic insight into the opioid crisis and enhance decision makers' ability to propose and consider policy options. Such work will require the integration of new structural components, new data, and new analyses into the model. Given the paucity of data surrounding opioids interventions, this effort will also require studies to collect information about the costs, social outcomes, and other details associated with potential policies.

The Substance Abuse and Mental Health Services Administration, Center for Mental Health Services is accepting applications for fiscal year (FY) 2015 PPHF-2015 Cooperative Agreements for State-Sponsored Youth Suicide Prevention and Early Intervention (Short Title: State/Tribal Youth Suicide Prevention Cooperative Agreements) (PPHF-2015). The purpose of this program is to support states and tribes (including Alaska Villages and urban Indian organizations) in developing and implementing statewide or tribal youth suicide prevention and early intervention strategies. The programs include collaboration among youth-serving institutions and agencies and should include schools, educational institutions, juvenile justice systems, foster care systems, substance abuse and mental health programs, and other child and youth supporting organizations; these efforts should include both a strong community component and a strong health system component. The ultimate goal of this program is to reduce suicide deaths and non-fatal suicide attempts. SAMHSA has demonstrated that behavioral health is essential to health, prevention works, treatment is effective, and people recover from mental and substance use disorders. Behavioral health services improve health status and reduce health care and other costs to society. Continued improvement in the delivery and financing of prevention, treatment and recovery support services provides a cost effective opportunity to advance and protect the nation's health. To continue to improve the delivery and financing of prevention, treatment and recovery support services, SAMHSA has identified six Strategic Initiatives to focus the Agency's work on improving lives and capitalizing on emerging opportunities. The State and Tribal Youth Suicide Prevention grants closely align with SAMHSA's Strategic Initiative on Prevention of Substance Abuse and Mental Illness. More information is available at the SAMHSA website: http://www.samhsa.gov/prevention. The

The PCC has supported world-class research since 2009, spending more than $8.0 M to support novel science. Research and grant-making are the foundation of the PCC and are the focus of everyday business activity. PCC-supported research contributes to a movement in addressing doping's root causes and ultimately decreasing the use of performance-enhancing drugs by all participants in all sports at all levels of play. With an emphasis on original work that focuses on improving existing analytical methods for detecting particular drugs, developing new analytical methods to test for substances not currently detectable, and discovering cost-effective approaches for testing widely abused substances across all levels of sport, the following areas of investigation reflect the PCC's current research priorities: - Developing methods of cost-effective testing to detect and deter the use of banned and illegal substances. - Developing testing protocols to detect designer substances used for doping purposes. - Improving existing analytical methods to detect particular drugs, ex. GH, IGF-1, EPO, hCG. - Developing analytical methods to detect performance enhancing drugs not currently detectable. - Longitudinal urinary excretion patterns, metabolism and dose-concentration. - Critical reviews to support interpretation of laboratory data. - Alternative specimens, (ex. oral fluid, dried blood/plasma spots) for testing.

With an emphasis on original work that focuses on improving existing analytical methods for detecting particular drugs, developing new analytical methods to test for substances not currently detectable, and discovering cost-effective approaches for testing widely abused substances across all levels of sport, the following areas of investigation reflect the PCC's current research priorities: - Developing methods of cost-effective testing to detect and deter the use of banned and illegal substances. - Developing testing protocols to detect designer substances used for doping purposes. - Improving existing analytical methods to detect particular drugs, ex. GH, IGF-1, EPO, hCG. - Developing analytical methods to detect performance enhancing drugs not currently detectable. - Longitudinal urinary excretion patterns, metabolism and dose-concentration. - Critical reviews to support interpretation of laboratory data. - Alternative specimens, (ex. oral fluid, dried blood/plasma spots) for testing.

Funds may be used to: Evaluate current landfill conditions to determine threats to water resources in rural areas; provide technical assistance and/or training to enhance operator skills in the maintenance and operation of active landfills in rural areas; provide technical assistance and/or training to help associations reduce the solid waste stream; and provide technical assistance and/or training for operators of landfills in rural areas which are closed or will be closed in the near future with the development/implementation of closure plans, future land use plans, safety and maintenance planning, and closure scheduling within permit requirements. Grant funds may not be used to: Recruit preapplications/applications for any loan and/or grant program including RUS Water and Waste Disposal Loan and/or Grant Program; duplication of current services, replacement or substitution of support previously provided such as those performed by an association's consultant in developing a project; fund political activities; pay for capital assets, the purchase of real estate or vehicles, improve and renovate office space, or repair and maintain privately-owned property; pay for construction or operation and maintenance costs of water and waste facilities; and pay costs incurred prior to the effective date of grants made under this subpart.

A. Purpose and Priorities The National Food Safety Training, Education, Extension, Outreach, and Technical Assistance Program will award grants that increase the understanding and adoption of established food safety standards, guidance, and protocols. Grants awarded through this program will be carried out in a manner that facilitates the integration of food safety standards and guidance with a variety of agricultural production systems, including conventional, sustainable, organic, and conservation and environmental practices carried out by the eligible entities. The assistance provided by these programs, to the extent practicable, shall be coordinated with and delivered in cooperation with similar services or assistance by other federal agencies or programs serving those eligible entities. The U.S. Food and Drug Administration (FDA) and the U.S. Department of Agriculture's National Institute of Food and Agriculture (NIFA) have joined in a collaborative partnership to administer and manage the National Food Safety Training, Education, Extension, Outreach, and Technical Assistance Program. This program is designed to develop a comprehensive food safety training, education and technical assistance program for those affected by the FDA Food Safety Modernization Act (FSMA). Specifically, this program will address the needs of owners and operators of small and medium-sized farms, beginning farmers, socially disadvantaged farmers, small processors, and small fresh fruit and vegetable merchant wholesalers. The joint program will award competitive grant funds that enable awardees to establish a National Coordination Center (NCC) for Food Safety Training, Education, Extension, Outreach, and Technical Assistance and Regional Centers (RC) for Food Safety Training, Education, Extension, Outreach, and Technical Assistance across the country for food safety training, education, and technical assistance. Project Teams for the RCs will reach out into local communities to work wi

The American Association for Cancer Research is accepting applications for its AACR NextGen Grants for Transformative Cancer Research program. The annual program is designed to stimulate highly innovative research from young investigators. Three-year grants of up to $450,000 will be awarded in support of creative, paradigm-shifting cancer research that might not be funded through conventional channels. The funds are intended to support expenses related to the research project, which may include salary and benefits of the grant recipient, postdoctoral or clinical research fellows, graduate students (including tuition costs), and research assistants; research/laboratory supplies and equipment; travel applicable to the research project; publication charges for manuscripts that pertain directly to the funded project; and other research expenses and indirect costs. Research projects must represent a highly innovative approach to a major contemporary challenge in cancer research. The research, which can be in any area of basic, translational or clinical science, must have the potential to lead to groundbreaking discoveries in the field and transform our understanding of the tumorigenesis process and/or ability to treat, detect, or prevent cancer. To be eligible, applicants must have a doctoral degree in a related field and not currently be a candidate for a further doctoral degree. In addition, at the start of the grant term on July 1, 2018, applicants must hold a tenure-eligible appointment at the level of assistant professor; have held this appointment for no more than three years; and work at an academic, medical, or research institution anywhere in the world. AACR membership is required.

Founded in 1996, the Marsha Rivkin Center for Ovarian Cancer Research provides funding for multiple efforts, including funding for innovative research pilot studies, scholar grants to up-and-coming investigators to encourage their careers in ovarian cancer research, public early detection screening for ovarian cancer, and nationally and internationally attended research symposia focused on ovarian cancer. To advance this mission, the center has issued a Call for Applications for its 2018 Scientific Scholar Awards. Through the program, the center will award grants of up $120,000 over two years to promising laboratory and clinical scientists interested in pursuing a career as an independent investigator in ovarian cancer research. Funds are for direct costs only; institutional overhead and indirect costs are not covered by the award. Eligible applicants must have an MD, PhD, or equivalent degree with career goals focused on ovarian cancer, and clinicians must have completed their residency. All applicants should be at the postdoc/fellow, instructor, research assistant, or assistant professor level, with no more than three to four years in any of these positions. Established outstanding scientists without prior focus in ovarian cancer but looking to focus in this area are also encouraged to apply.

This notice announces the opportunity to apply for funding under the Rural Health Innovation and Transformation Technical Assistance (RHIT-TA) program. The purpose of this program is to provide technical assistance (TA) to rural stakeholders and the public to help them understand and engage in the value-based care landscape in the context of rural health care. In an effort to control health care costs and improve the quality of care, public and private payers have increasingly implemented initiatives to encourage value-based care. Value-based care programs reward health care providers for the quality of care through the realignment of financial incentives towards value over volume. Because of the unique economic factors affecting rural providers, the implementation and effects of value-based care initiatives may look different in rural, low-volume settings. For example, low patient volumes, along with low margins, in rural settings can make it more difficult to absorb the financial risks associated with value-based care. Start-up costs for value-based care may seem prohibitive for some, while small volumes may make it more difficult to measure value and may increase the risk of skewed outcomes. At the same time, value-based care initiatives are evolving towards risk-based models, and there is a need to help stakeholders and the public understand how these changes affect rural health care. Therefore, a major goal of this funding opportunity is to support the ability of rural providers to participate and succeed in current and emerging payment and delivery system models designed to provide value-based care. Value-based care is one of the four priorities of the United States Department of Health and Human Services (HHS).

Through the program, one-year grants of up to $40,000 will be awarded to projects that investigate various aspects of hearing and balance disorders related to the inner ear. Priority will be given to investigators early in their careers who need seed funds to generate results and data that can be used to support applications for larger grants (i.e., NIH grants) in the future. Projects should relate to the hearing or balance functions of the ear. Both basic and clinical studies that investigate aspects of the auditory and vestibular systems, including but not limited to genetics, neurotology, anatomy, auditory processing, molecular and cellular biology, therapeutic studies, and investigations of current or experimental devices (i.e., cochlear implants), may be proposed. Funding may only be used for direct costs, including salaries of technical and supporting staff, equipment related to the research, and supplies. The grants will not support the salary of the principal investigator, travel or conference attendance, or educational costs.

The Tell Every Amazing Lady About Ovarian Cancer Louisa M. McGregor Ovarian Cancer Foundation, also known as T.E.A.L.®, is accepting applications for its 2018 Medical Research Program. The program, which aids in the advancement of ovarian cancer treatment research and the need for a screening test, offers funding in support of ovarian cancer research studies that are deemed to be most aligned with T.E.A.L.®'s mission by the organization's board of directors and a scientific advisory board. This year, the program has special interest in research related to the p53 gene, although it will accept proposals for other research related to ovarian cancer. In 2018, T.E.A.L.® will award one-year grants of up to $50,000. Project costs must be thoroughly outlined in the budget portion of the application, and grants cannot be applied to indirect costs or PI salary. All applicants must be affiliated with a non-for-profit institution in the United States and must complete all sections of the online application found here: https://goo.gl/forms/Bvk0RrwpnnQbYIjC3. (Applications from for profit organizations or federal or state government agencies will not be considered.) The deadline to submit proposals is May 31, 2018.