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The goal of theBiomedical Engineering(BME)program is to provide research opportunities to develop novel ideas into discovery-level and transformative projects that integrate engineering and life sciences in solving biomedical problems that serve humanity in the long-term. BME projects must be at the interface of engineering and life sciences, and advance both engineering and life sciences. The projects should focus on high impact transformative methods and technologies. Projects should include methods, models and enabling tools of understanding and controlling living systems; fundamental improvements in deriving information from cells, tissues, organs, and organ systems; new approaches to the design of structures and materials for eventual medical use in the long-term; and novel methods for reducing health care costs through new technologies. The long-term impact of the projects can be related to fundamental understanding of cell and tissue function, effective disease diagnosis and/or treatment, improved health care delivery, or product development.

The goal of theBiomedical Engineering(BME)program is to provide research opportunities to develop novel ideas into discovery-level and transformative projects that integrate engineering and life sciences in solving biomedical problems that serve humanity in the long-term. BME projects must be at the interface of engineering and life sciences, and advance both engineering and life sciences. The projects should focus on high impact transformative methods and technologies. Projects should include methods, models and enabling tools of understanding and controlling living systems; fundamental improvements in deriving information from cells, tissues, organs, and organ systems; new approaches to the design of structures and materials for eventual medical use in the long-term; and novel methods for reducing health care costs through new technologies. The long-term impact of the projects can be related to fundamental understanding of cell and tissue function, effective disease diagnosis and/or treatment, improved health care delivery, or product development.

The NIH Research Education Program (R25) supports research education activities in the mission areas of the NIH. The over-arching goal of this NIBIB R25 program is to support educational activities that include innovative approaches to enhance biomedical engineering design education to ensure a future workforce that can meet the nations needs in biomedical research and healthcare technologies. To accomplish the stated over-arching goal, this FOA will support creative educational activities with a primary focus on Courses for Skills Development. This FOA encourages applications from institutions that propose to establish new or to enhance existing team-based design courses or programs in undergraduate biomedical engineering departments or other degree-granting programs with biomedical engineering tracks/minors. This FOA targets undergraduate students. While current best practices such as multidisciplinary/interdisciplinary education, introduction to the regulatory pathway and other issues related to the commercialization of medical devices, and clinical immersion remain encouraged components of a strong BME program, this FOA also challenges institutions to propose other novel, innovative and/or ground-breaking activities that can form the basis of the next generation of biomedical engineering design education.

The National Center for Science and Engineering Statistics (NCSES) of the National Science Foundation (NSF) is one of the thirteen principal federal statistical agencies within the United States. It is responsible for the collection, acquisition, analysis, reporting and dissemination of objective, statistical data related to the science and engineering enterprise in the United States and other nations that is relevant and useful to practitioners, researchers, policymakers and the public. NCSES uses this information to prepare a number of statistical data reports as well as analytical reports including the National Science Board's biennial report, Science and Engineering (S&E) Indicators, and Women, Minorities and Persons with Disabilities in Science and Engineering. The Center would like to enhance its efforts to support analytic and methodological research in support of its surveys, and to engage in the education and training of researchers in the use of large-scale nationally representative datasets. NCSES welcomes efforts by the research community to use NCSES data for research on the science and technology enterprise, to develop improved survey methodologies for NCSES surveys, to create and improve indicators of S&T activities and resources, and strengthen methodologies to analyze and disseminate S&T statistical data. To that end, NCSES invites proposals for individual or multi-investigator research projects, doctoral dissertation improvement awards, workshops, experimental research, survey research and data collection and dissemination projects under its program for Research on the Science and Technology Enterprise: Statistics and Surveys.

The LEAP HI program challenges the engineering research community to take a leadership role in addressing demanding, urgent, and consequential challenges for advancing America’s prosperity, health and infrastructure. LEAP HI proposals confront engineering problems that are too complex to yield to the efforts of a single investigator --- problems that require sustained and coordinated effort from interdisciplinary research teams, with goals that are not achievable through a series of smaller, short-term projects. LEAP HI projects perform fundamental research that may lead to disruptive technologies and methods, lay the foundation for new and strengthened industries, enable notable improvements in quality of life, or reimagine and revitalize the built environment. LEAP HI supports fundamental research projects involving collaborating investigators, of duration up to five years, with total budget between $1 million and $2 million. LEAP HI proposals must articulate a fundamental research problem with compelling intellectual challenge and significant societal impact, particularly on economic competitiveness, quality of life, public health, or essential infrastructure. One or more CMMI core topics must lie at the heart of the proposal, and integration of disciplinary expertise not typically engaged in CMMI-funded projects is encouraged. LEAP HI proposals must highlight engineering research in a leadership role. LEAP HI proposals must demonstrate the need for a sustained research effort by an integrated, interdisciplinary team, and should include aresearch integrationplan and timeline for research activities, with convincing mechanisms for frequent and effective communication.

The Electrical, Communications and Cyber Systems Division (ECCS) supports enabling and transformative engineering research at the nano, micro, and macro scales that fuels progress in engineering system applications with high societal impact. This includes fundamental engineering research underlying advanced devices and components and their seamless penetration in power, controls, networking, communications or cyber systems. The research is envisioned to be empowered by cutting-edge computation, synthesis, evaluation, and analysis technologies and is to result in significant impact for a variety of application domains in healthcare, homeland security, disaster mitigation, telecommunications, energy, environment, transportation, manufacturing, and other systems-related areas. ECCS also supports new and emerging research areas encompassing 5G and Beyond Spectrum and Wireless Technologies, Quantum Information Science, Artificial Intelligence, Machine Learning, and Big Data.

The Presidential Awards for Excellence in Science, Mathematics, and Engineering Mentoring (PAESMEM) is a Presidential award established by the White House in 1995. The purpose of the award is to recognize U.S. citizens or permanent residents and U.S. organizations that have demonstrated excellence in mentoring individuals from groups that are underrepresented in science, technology, engineering, and mathematics (STEM) education and workforce. Groups that are underrepresented in STEM include women, people with disabilities, underrepresented racial and ethnic minorities, as well as individuals from low socio-economic backgrounds and some geographic regions such as urban and rural areas. The PAESMEM program is administered by the National Science Foundation (NSF) on behalf of the White House Office of Science and Technology Policy (OSTP). Nominations, including self-nominations, are invited for Individual and Organizational PAESMEM awards. Individuals and organizations in all public and private sectors are eligible including industry, academia, primary and secondary education, military and government, non-profit organizations, and foundations. Nominations are encouraged from all geographical regions in the U.S., its territories or possessions, particularly jurisdictions designated by Congress under NSF's Experimental Program to Stimulate Competitive Research (EPSCoR).

The Ethics Education in Science and Engineering (EESE) program funds research and educational projects that improve ethics education in all fields of science and engineering that NSF supports, with priority consideration given to interdisciplinary, inter-institutional, and international contexts.  Although the primary focus is on improving ethics education for graduate students in NSF-funded fields, the proposed programs may benefit advanced undergraduates as well.

Purpose This Funding Opportunity Announcement (FOA) invites applications that propose transformative engineering solutions to technical challenges associated with new development, substantial optimization of existing technologies and clinical translation of intraoral biodevices. Proposed technologies are expected to advance development of oral biodevices to clinical use, including but not limited to: precision medicine-based detection, diagnosis and treatment of oral and overall health conditions, and measurement of patient functional status and clinical outcome assessment. Areas of interest in this FOA include engineering approaches that allow integration of electronic, physical, and biological systems essential to the development of functional biodevices that are safe and effective for detection, diagnosis and treatment of oral and systemic disease. Products of this research will be proof-of-concept prototype biodevices, dedicated biosensors, associated core technologies and integrated approaches that enable development of safe and effective intra-oral biodevices intended for specific clinical applications. To streamline the development of oral biodevices that advance precision medicine-based approaches in clinical practice, this FOA encourages interdisciplinary collaborations across engineering, multifunctional sensors, pharmacology, chemistry, medicine, and dentistry, as well as between academia and industry.

Type 1 diabetes (T1D) results in part from the autoimmune-mediated dysfunction or destruction of insulin-producing pancreatic beta cells. This funding opportunity is for projects that seek to discover ways to change the course of the disease by directly establishing tolerance. Immune responses could be engineered for tolerance induction through the manipulation of antigens, cells, or cellular microenvironments. Collaborations between T1D experts and investigators from other fields, including (but not limited to) cancer immunology and biomaterials engineering, are especially encouraged.

The LEAP HI program challenges the engineering research community to take a leadership role in addressing demanding, urgent, and consequential challenges for advancing America's prosperity, health and infrastructure. LEAP HI proposals confront engineering problems that are too complex to yield to the efforts of a single investigator --- problems that require sustained and coordinated effort from interdisciplinary research teams, with goals that are not achievable through a series of smaller, short-term projects. LEAP HI projects perform fundamental research that may lead to disruptive technologies and methods, lay the foundation for new and strengthened industries, enable notable improvements in quality of life, or reimagine and revitalize the built environment.

The goal of the interagency Smartand Connected Health (SCH): Connecting Data, People and Systems program is to accelerate the development and integration of innovative computer and information scienceand engineering approaches to support the transformation of health and medicine. Approaches that partner technology-based solutions with biomedical and biobehavioral research are supported by multiple agencies of the federal government including the National Science Foundation (NSF) and the National Institutes of Health (NIH). The purpose of this program is to develop next-generation multidisciplinary science that encourages existing and new research communities to focus on breakthrough ideas in a variety of areas of value to health, such as networking, pervasive computing, advanced analytics, sensor integration, privacy and security, modeling of socio-behavioral and cognitive processes and system and process modeling. Effective solutions must satisfy a multitude of constraints arising from clinical/medical needs, barriers to change, heterogeneity of data, semantic mismatch and limitations of current cyberphysical systems and an aging population.Such solutions demand multidisciplinary teams ready to address issues ranging from fundamental science and engineering to medical and public health practice.

ype 1 diabetes (T1D) results in part from the autoimmune-mediated dysfunction or destruction of insulin-producing pancreatic beta cells. This funding opportunity is for projects that seek to discover ways to change the course of the disease by directly establishing tolerance. Immune responses could be engineered for tolerance induction through the manipulation of antigens, cells, or cellular microenvironments. Collaborations between T1D experts and investigators from other fields, including (but not limited to) cancer immunology and biomaterials engineering, are especially encouraged.

The goal of the interagency Smart and Connected Health (SCH): Connecting Data, People and Systems program is to accelerate the development and integration of innovative computer and information science and engineering approaches to support the transformation of health and medicine. Approaches that partner technology-based solutions with biomedical and biobehavioral research are supported by multiple agencies of the federal government including the National Science Foundation (NSF) and the National Institutes of Health (NIH). The purpose of this program is to develop next-generation multidisciplinary science that encourages existing and new research communities to focus on breakthrough ideas in a variety of areas of value to health, such as networking, pervasive computing, advanced analytics, sensor integration, privacy and security, modeling of socio-behavioral and cognitive processes and system and process modeling. Effective solutions must satisfy a multitude of constraints arising from clinical/medical needs, barriers to change, heterogeneity of data, semantic mismatch and limitations of current cyberphysical systems and an aging population. Such solutions demand multidisciplinary teams ready to address issues ranging from fundamental science and engineering to medical and public health practice.

The goal of the interagency Smart and Connected Health (SCH): Connecting Data, People and Systems program is to accelerate the development and integration of innovative computer and information science and engineering approaches to support the transformation of health and medicine. Approaches that partner technology-based solutions with biomedical and biobehavioral research are supported by multiple agencies of the federal government including the National Science Foundation (NSF) and the National Institutes of Health (NIH). The purpose of this program is to develop next-generation multidisciplinary science that encourages existing and new research communities to focus on breakthrough ideas in a variety of areas of value to health, such as networking, pervasive computing, advanced analytics, sensor integration, privacy and security, modeling of socio-behavioral and cognitive processes and system and process modeling. Effective solutions must satisfy a multitude of constraints arising from clinical/medical needs, barriers to change, heterogeneity of data, semantic mismatch and limitations of current cyberphysical systems and an aging population. Such solutions demand multidisciplinary teams ready to address issues ranging from fundamental science and engineering to medical and public health practice.

To foster innovative collaborative approaches to research projects that propose novel pairings of investigators from at least two broadly disparate disciplines. The proposal must focus on the collaborative relationship, such that the scientific objectives could not be achieved without the efforts of at least two co-principal investigators and their respective disciplines. The combination and integration of studies may be inclusive of basic, clinical, population, behavioral, and/or translational research. Projects must include at least one Co-PI from a field outside cardiovascular disease and stroke. This award is also intended to foster collaboration between established and early- or mid-career investigators. Applications by existing collaborators are permitted, provided that the proposal is for a new and novel idea or approach that has not been funded before. Multidisciplinary research broadly related to cardiovascular function, cardiovascular disease, and stroke, or to related clinical, basic science, bioengineering, biotechnology, or public health problems. Proposals are encouraged from all basic science disciplines as well as epidemiological, behavioral, community and clinical investigations that bear on cardiovascular and stroke problems. AHA awards are open to the array of academic and health professionals. This includes but is not limited to all academic disciplines (biology, chemistry, engineering, mathematics, technology, physics, etc.) and all health-related professions (physicians, nurses, advanced practice nurses, pharmacists, dentists, physical and occupational therapists, statisticians, nutritionists, behavioral scientists, health attorneys, engineers, etc.).

The Agency for Healthcare Research and Quality (AHRQ) funds research leading to patient safety improvements in all settings and systems of care delivery. While many researchers have endorsed a systems model as a way of thinking about entrenched patient safety problems, there has been a scarcity of programmatic activity that actually engages in new design and systems engineering effort, and that is focused on more than singular patient safety concerns. This P30 FOA calls for the creation and utilization of Patient Safety Learning Laboratories. These learning laboratories are places and professional networks where closely related threats to patient safety can be identified, where multidisciplinary teams generate new ways of thinking with respect to the threats, and where environments are established conducive to brainstorming and rapid prototyping techniques that stimulate further thinking. Learning laboratories further enable multiple develop-test-revise iterations of promising design features and subsystems of the sort that can be found in larger-scale engineering projects. Once the closely aligned projects or subsystems are developed, integrated, and implemented as an overall working system, the ultimate function of the learning laboratory is to evaluate the system in a realistic simulated or clinical setting with its full complement of facility design, equipment, people (patients, family members, and providers), new procedures and workflow, and organizational contextual features, as appropriate.

WHO CAN APPLY? I-Corps@Ohio funds will be offered on a competitive basis to teams of faculty researchers and graduate students developing institution-based technologies from Ohio colleges and universities. Under the supervision of business and entrepreneurial mentors, teams will develop market-driven value propositions and scalable business models around their technologies and attract follow on funding to support company formation and market entry. APPLICATION PROCESS The I-Corps@Ohio proposal submission process consists of five steps: 1. mandatory meeting with the appropriate TTO representative(s) at the PI's institution; 2. team selection of technology track (science and engineering or medtech); 3. registration of all team members in the online portal; 4. proposal submission; and 5. full team interview with I-Corps@Ohio program representatives. All teams are required to complete the online profile and submission questionnaire beginning October 23, 2019. Deadline to apply is January 15, 2019. The PI may complete this information or designate another member of the team as the lead member. Subsequent members of the team will be invited to join by the lead member through the application portal and must complete his or her profile. Every effort should be made to identify all team members prior to submitting the online proposal submission questionnaire. Additional team members may be added later. You will be asked to select from two tracks: Medtech Track: Teams will select Medtech Track if the subject technology is in the form of medical devices, diagnostics, medicines, vaccines, software, testing procedures and systems and is developed to solve a health/clinical problem and improve the quality of human life. Science and Engineering (S&E) Track: Teams will select S&E Track if the technology does not fit into the Medtech category.

The purpose of this Funding Opportunity Announcement (FOA) is to promote the development of in vitro platforms that recapitulate components of the human immune system. Applications that qualify for this funding will focus on engineering 3-D in vitro microphysiological immune system tissues, adding immune system responsiveness to existing in vitro platforms, and/or in vitro modeling autoimmune diseases and inflammation.

Purpose of Program: The purpose of the RERC program is to improve the effectiveness of services authorized under the Rehabilitation Act by conducting advanced engineering research on and development of innovative technologies that are designed to solve particular rehabilitation problems or to remove environmental barriers. RERCs also demonstrate and evaluate such technologies, facilitate service delivery system changes, stimulate the production and distribution of new technologies and equipment in the private sector, and provide training opportunities. NIDILRR seeks to fund an RERC on Technologies to Promote Exercise and Health Among People with Disabilities. This RERC must investigate access to exercise by people with disabilities in both recreational and clinical settings and evaluate the impact of exercise on health outcomes of people with disabilities.

The purpose of the Mentored Quantitative Research Career Development Award (K25) is to attract to NIH-relevant research those investigators whose quantitative science and engineering research has thus far not been focused primarily on questions of health and disease.  The K25 award will provide support and "protected time" for a period of supervised study and research for productive professionals with quantitative (e.g., mathematics, statistics, economics, computer science, imaging science, informatics, physics, chemistry) and engineering backgrounds to integrate their expertise with NIH-relevant research.