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MiamiOH OARS

PA-18-504: Academic Research Enhancement Award (Parent R15 Clinical Trial Not Allowed) - 0 views

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    The purpose of the Academic Research Enhancement Award (AREA) program is to stimulate research in educational institutions that provide baccalaureate or advanced degrees for a significant number of the Nation's research scientists, but that have not been major recipients of NIH support. AREA grants create opportunities for scientists and institutions otherwise unlikely to participate extensively in NIH research programs to contribute to the Nation's biomedical and behavioral research effort. AREA grants are intended to support small-scale research projects proposed by faculty members of eligible, domestic institutions, to expose undergraduate and/or graduate students to meritorious research projects, and to strengthen the research environment of the applicant institution.   

MiamiOH OARS

RFA-AA-18-008: Interaction of HIV Infection and Alcohol Abuse on Central Nervous System... - 0 views

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    The National Institute on Alcohol Abuse and Alcoholism (NIAAA) invites applications to evaluate the cumulative and progressive effects on brain structure and cognitive/behavioral function of combined HIV infection and alcohol abuse. This project has recruited and longitudinally tracked a large cohort of individuals with HIV infection, or alcohol abuse, or the comorbid condition. As members of this cohort are growing older and living well longer due to antiretroviral medications, this project is well suited to address several questions of current interest in the HIV-AIDS research community. These questions include the effects of coinfection with the Hepatitis C virus, the involvement of peripheral neuropathy as a factor in frailty, potential neurotoxic effects of antiretroviral medications, and interactive effects with advancing age on sensory and motor functioning.
MiamiOH OARS

RFA-HD-19-013: The Role of Stem/Progenitor Cells in the Pathogenesis and Treatment of G... - 0 views

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    The purpose of the Funding Opportunity Announcement (FOA) is to encourage research into the role of pluripotent progenitor/stem cells in the pathogenesis and treatment of selected gynecologic disorders, specifically uterine fibroids, endometriosis, adenomyosis, endometrial polyps, and pelvic organ prolapse.

MiamiOH OARS

RFA-DA-18-019: NIDA Avant-Garde Award Program for HIV/AIDS and Drug Use Research (DP1, ... - 0 views

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    The NIDA Avant-Garde Award Program for HIV/AIDS Research supports individual scientists of exceptional creativity who propose high-impact research that will open new areas of HIV/AIDS research relevant to drug abuse and/or lead to new avenues for prevention and treatment of HIV/AIDS among drug abusers. The term "avant-garde" is used to describe highly innovative approaches that have the potential to be transformative. The proposed research should reflect approaches and ideas that are substantially different from those already being pursued by the investigator or others and should support the NIH HIV/AIDS Research Priorities https://grants.nih.gov/grants/guide/notice-files/NOT-OD-15-137.html. The NIDA Avant-Garde award supports innovative, basic research that may lead to improved preventive interventions or therapies; creative, new strategies to prevent disease transmission; novel approaches to improve disease outcomes; and creative approaches to eradicating HIV or improving the lives of those living with HIV.

MiamiOH OARS

RFA-DK-17-035: Microphysiological Systems (MPS) for Modeling Diabetes (UG3/UH3 Clinical... - 0 views

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    NIDDK requests applications to join a new research consortium "Microphysiological Systems (MPS) for Modeling Diabetes (MPS-MOD)". NIDDK will support the development and validation of human tissue chips that closely mimic the normal physiology of key metabolic tissues, including the pancreatic islet, liver, skeletal muscle, and white adipose tissue (WAT). Experimental designs for the MPS-MOD platforms should incorporate strategies to measure pathophysiological changes associated with metabolic disease, including the impact of immune cells on metabolic dysfunction. Once developed, these multi-dimensional MPS-MOD platforms will serve as the foundation for NIDDK's advanced strategy to identify new and novel therapeutics for diabetes. The utility and validity of model systems developed under this initiative will be measured, in part, through the ability of known diabetes therapeutic agents and biomarkers to influence biology of the system, using best practices and rigorous study design. The need for high-quality, well-characterized isogenic/patient derived iPSC (induced pluripotent stem cell) lines and standardized differentiation procedures is a critical step in turning disease-specific lines into tools for discovery. In the future, iPSC-based human tissue chips could play a central role in drug development, testing, screening, drug repurposing and toxicity testing.
MiamiOH OARS

PAR-18-487: NIDCD Early Career Research(ECR) Award (R21 - Clinical Trials Optional) - 0 views

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    The NIDCD Early Career Research (ECR) Award (R21) is intended to support both basic and clinical research from scientists who are beginning to establish an independent research career. It cannot be used for thesis or dissertation research. The research must be focused on one or more of the areas within the biomedical and behavioral scientific mission of the NIDCD: hearing, balance, smell, taste, voice, speech, or language. The NIDCD ECR Award R21 grant mechanism supports different types of projects including secondary analysis of existing data; small, self-contained research projects; development of research methodology; translational research; outcomes research; and development of new research technology. Irrespective of the type of project, the intent of the NIDCD ECR Award R21 is for the Program Director(s)/Principal Investigator(s) (PD(s)/PI(s)) to obtain sufficient preliminary data for a subsequent R01 application.
    Only one NIDCD Early Career Research Award (ECR) application may be submitted by a PD/PI per due date. Applicants will be considered ineligible for this funding opportunity if they submit an R01, R03, R15 or any other R21 application, with NIDCD as the primary IC, for the same review cycle that the NIDCD ECR Award (R21) application is submitted.
MiamiOH OARS

PA-18-492: Using Information Technology to Support Systematic Screening and Treatment o... - 0 views

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    The purpose of this Funding Opportunity Announcement (FOA) is to: identify new, information technology (IT)-enabled delivery models that support systematic screening and treatment of depression in cancer patients; test the feasibility of implementing these new delivery models in a variety of oncology practice settings, especially those serving under-served populations; and test the usability and potential effectiveness of the IT-specific components of these new delivery models. Also listed under R01
MiamiOH OARS

PA-18-485: Studies in Neonatal and Pediatric Resuscitation (R01 Clinical Trial Optional) - 0 views

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    The purpose of this funding opportunity announcement (FOA) is to stimulate research on a wide range of topics related to neonatal and pediatric resuscitation. Possible topics may include, but are not limited to: fetal-neonatal transitional cardiovascular and pulmonary physiology, optimizing steps of resuscitation, management of third stage of labor and its effect on the fetus, resuscitation of children with malformations, effect of resuscitation on long-term outcomes and post-resuscitation practices. Applications can include epidemiological studies, studies utilizing fetal-neonatal animal models, computer or other information-technology-based simulations or study designs, clinical observational studies, analyses of pre-existing national or regional datasets, opportunistic studies, prospective randomized controlled trials, or any combinations thereof. It is anticipated that the results from well-conducted studies will enable translation of knowledge into evidence-based resuscitation practices ensuring a optimal short- and long-term outcomes for all newborn infants and children.
MiamiOH OARS

Prevention and Treatment Research to Address HIV/AIDS Disparities in Women in the US (R... - 0 views

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    The purpose of this initiative is to support health services, intervention, and implementation research to understand and reduce racial/ethnic, geographic, and socioeconomic HIV disparities in US women. Projects may address HIV prevention, screening and diagnosis, and/or treatment. Projects may involve primary data collection and/or secondary analysis of existing data.
MiamiOH OARS

Community Access to Child Health Seeks Applications for Community Health Programs | RFP... - 0 views

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    To that end, CATCH is accepting applications for its CATCH Planning and Implementation Grants program and CATCH Resident Grants program.

    1) Planning and Implementation Grants: Grants of up to $10,000 will be awarded to individual pediatricians and fellowship trainees for the planning of innovative community-based child health initiatives that ensure all children in the community have access to healthcare services not otherwise available. Priority will be given to projects that serve communities with the greatest health disparities. Outreach must be to the community at large, not to practice or clinic patients only, and all initiatives should incorporate screening for or connecting children to medical homes and available insurance programs.

    All pediatricians are eligible to apply regardless of employment setting or retirement status.

    2) Resident Grants: Grants of up to $2,000 will be awarded to pediatric residents for the planning and/or implementation of community-based child health initiatives. Projects must include planning activities or demonstrate completed planning activities, and may include implementation activities.
MiamiOH OARS

RFA-NS-18-017: Planning Grant to Develop Phase III Clinical Trials for Lewy Body Dement... - 0 views

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    The purpose of this FOA is to provide one year of support for planning activities necessary for initiating a Phase III clinical trial designed to treat patients with Lewy Body Dementias (LBD), which include Dementia with Lewy Bodies and Parkinson's Disease Dementia. Such activities may include identifying trial sites/collaborators, designing trial protocols and procedures, and addressing regulatory approvals.
MiamiOH OARS

PAR-18-431: Pilot Effectiveness Trials for Post-Acute Interventions and Serivces to Opt... - 0 views

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    NIMH seeks applications for pilot effectiveness projects to evaluate the preliminary effectiveness of therapeutic and service delivery interventions for the post-acute management of mental health conditions that are matched to the stage of illness in terms of both their focus (e.g., consolidating and maintaining gains from initial treatment, managing residual symptoms/impairment, preventing relapse, promoting adherence and appropriate service use) and intensity/burden. In this pilot phase of effectiveness research, the trial should be designed to evaluate the feasibility, tolerability, acceptability, safety, and potential effectiveness of the approach; to address whether the intervention engages the target(s)/mechanisms(s) that is/are presumed to underlie the intervention effects; and to obtain preliminary data needed as a pre-requisite to a larger-scale effectiveness trial (e.g., comparative effectiveness study, practical trial) designed to definitely test the effectiveness of interventions to improve post-acute outcomes.
MiamiOH OARS

PAR-18-430: Effectiveness Trials for Post-Acute Interventions and Services and Services... - 0 views

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    NIMH seeks applications for research projects to evaluate the effectiveness of therapeutic and service delivery interventions for the post-acute management of mental health conditions affecting youth, adults, and older adults. This FOA encourages clinical trials to establish the effectiveness and test hypotheses regarding moderators, mediators, and mechanisms of action of post-acute phase therapeutic and services interventions that are matched to the stage of illness in terms of both their focus (e.g., consolidating and maintaining gains from initial treatment, managing residual symptoms/impairment, preventing relapse, promoting adherence and appropriate service use) and intensity/burden for promoting optimal longer-term outcomes.
MiamiOH OARS

PAR-18-427: First in Human and Early Stage Clinical Trials of Novel Investigational Dru... - 0 views

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    The purpose of this Funding Opportunity Announcement (FOA) is to encourage cooperative agreement applications to support early stage clinical trials of novel mechanism of action, investigational drugs or drug candidates for the treatment of psychiatric disorders in areas of unmet medical need. The FOA will support milestone-driven early stage trials in pediatric and adult populations. First in human (FIH) and Phase Ib studies of novel Agents must assess target engagement (brain exposure), pharmacological effects, safety, and tolerability to assess feasibility for Phase II/proof of concept (PoC) studies in psychiatric disorders. Phase II/PoC studies must evaluate the drug's impact on clinically relevant physiological systems (functional measures) and clinical indicators of effect. The FOA also supports FIH and early feasibility studies (EFS) of novel devices to evaluate target engagement, safety, tolerability, and efficacy. The overall objective is to facilitate rapid collection of data to "de-risk" novel mechanism of action investigational drugs, novel drugs for use in pediatric populations with psychiatric disorders, and devices or combination treatments in order to attract private funding for further clinical development as FDA-approved treatments.
MiamiOH OARS

PA-18-484: NIH Research Project Grant (Parent R01 Clinical Trial Not Allowed) - 0 views

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    The NIH Research Project Grant supports a discrete, specified, circumscribed project in areas representing the specific interests and competencies of the investigator(s). The proposed project must be related to the programmatic interests of one or more of the participating NIH Institutes and Centers (ICs) based on their scientific missions.
MiamiOH OARS

PA-18-482: NICHD Exploratory/Developmental Research Grant (R21 - Clinical Trial Optional) - 0 views

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    The NICHD Exploratory/Developmental Grant program supports exploratory and developmental research projects that fall within the NICHD mission by providing support for the early and conceptual stages of these projects. These studies may involve considerable risk but may lead to a breakthrough in a particular area, or to the development of novel techniques, agents, methodologies, models, or applications that could have a major impact on a field of biomedical, behavioral, or clinical research.
MiamiOH OARS

PA-18-465: Developing the Therapeutic Potential of the Endocannabinoid System for Pain ... - 0 views

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    The purpose of this Funding Opportunity Announcement (FOA) is to support projects that will elucidate the therapeutic potential of the cannabinoids and endocannabinoid system in the development of mechanism-based therapies for pain.
MiamiOH OARS

Long-term Assistance and SErvices for Research (LASER) - 0 views

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    Through LASER, USAID seeks to leverage and support international university networks, inclusive of universities from both the United States (U.S) and lower-middle income countries (LMIC), to improve development research opportunities, evidence generation, and uptake by development actors and policy makers. As part of the Cooperative Agreement, USAID will support a recipient to identify new research questions, fund research activities, translate research results into development impact, and build capacity of local higher education institutions and researchers. USAID seeks to support a recipient with a defined plan to achieve these goals, with the specific details and workplan proposed by the recipient, in consultation with USAID. USAID specifically seeks to support an implementing partner whose workplan includes the creation, engagement, and/or growth of a large, international network of university researchers, centers, and institutes across disciplines that can 1) independently identify and address new and impactful research questions with high relevance to the international development community AND 2) partner with USAID Missions, Bureaus, and Independent Offices (M/B/IOs) to address unique research needs identified by USAID. Additionally, USAID seeks to increase the human and institutional capacity of LMIC HEIs through LASER.
MiamiOH OARS

Search Grants | GRANTS.GOV - 0 views

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    The purpose of this notice of funding opportunity (NOFO) is to: 1) obtain a better understanding of the factors contributing to disparities in vaccination coverage observed between adolescents living in rural areas compared to adolescents living in urban areas within the United States for all recommended vaccines, with a special emphasis on human papilloma virus (HPV) vaccine; and 2) implement and evaluate an intervention(s) to improve vaccination coverage among adolescents living in rural areas.
MiamiOH OARS

RFA-DK-18-001: Silvio O. Conte Digestive Diseases Research Core Centers (P30 Clinical T... - 0 views

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    This Funding Opportunity Announcement (FOA) invites applications for Silvio O. Conte Digestive Diseases Research Core Centers (DDRCCs). The DDRCCs are part of an integrated program of digestive and liver diseases research support provided by the NIDDK. The purpose of this Centers program is to bring together basic and clinical investigators as a means to enhance communication, collaboration, and effectiveness of ongoing research related to digestive and/or liver diseases. DDRCCs are based on the core concept, whereby shared resources aimed at fostering productivity, synergy, and new research ideas among the funded investigators are supported in a cost-effective manner. Each proposed DDRCC must be organized around a central theme that reflects the focus of the digestive or liver diseases research of the Center members. The central theme must be within the primary mission of NIDDK, and not thematic areas for which other NIH Institutes or Centers are considered the primary source of NIH funding.
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