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The National Science Foundation (NSF) and the National Institutes of Health (NIH) are interested in proposals that will propel our understanding of the biomedical research enterprise by drawing from the scientific expertise of the science of science policy research community. NSF promotes the progress of science by maintaining the general health of research and education across all fields of science and engineering. The Social, Behavioral, and Economic Sciences (SBE) Directorate within the NSF supports basic research on people and society. The SBE sciences focus on human behavior and social organizations and how social, economic, political, cultural, and environmental forces affect the lives of people from birth to old age and how people in turn shape those forces. SBE's Science of Science and Innovation Policy (SciSIP) program supports research designed to advance the scientific basis of science and innovation policy.

The purpose of this Funding Opportunity Announcement (FOA) is to support high quality and impactful conferences/scientific meetings that are convened by data science related organizations whose missions focus on biomedical data science. This FOA, which uses the NIH conference cooperative agreement program (U13), is part of the NIH-wide initiative, Big Data to Knowledge (BD2K). Data science related organizations have a critical role in advancing biomedical data science but often depend on meetings to carry out their work. This FOA will support high quality conferences or meetings that are relevant to the biomedical data science needs of the participating Institutes and Centers of the National Institutes of Health. For the purpose of this FOA, a conference is defined as a gathering, such as in the form of a symposium, seminar, scientific meeting, workshop, or any other organized and formal meeting where persons assemble to coordinate, exchange, and disseminate information, or to explore or clarify a defined subject, problem, or area of knowledge.  Applicants representing data science related organizations may request support for one or a series of meetings over multiple years that address areas of data science aligned with the goals of the NIH BD2K program.

The purpose of this Funding Opportunity Announcement (FOA) is to support high quality and impactful conferences/scientific meetings that are convened by data science related organizations whose missions focus on biomedical data science. This FOA, which uses the NIH conference cooperative agreement program (U13), is part of the NIH-wide initiative, Big Data to Knowledge (BD2K). Data science related organizations have a critical role in advancing biomedical data science but often depend on meetings to carry out their work. This FOA will support high quality conferences or meetings that are relevant to the biomedical data science needs of the participating Institutes and Centers of the National Institutes of Health. For the purpose of this FOA, a conference is defined as a gathering, such as in the form of a symposium, seminar, scientific meeting, workshop, or any other organized and formal meeting where persons assemble to coordinate, exchange, and disseminate information, or to explore or clarify a defined subject, problem, or area of knowledge.  Applicants representing data science related organizations may request support for one or a series of meetings over multiple years that address areas of data science aligned with the goals of the NIH BD2K program.

Research proposals are sought from educational institutions, nonprofit organizations, and commercial organizations for research in materials sciences; ballistics and aeromechanics sciences; information sciences; human sciences; survivability, lethality, and vulnerability analysis and assessment; chemistry; electronics; physics; environmental sciences; life sciences; mechanical sciences, mathematical sciences, computing sciences and network sciences. Proposals will be evaluated only if they are for scientific study and experimentation directed toward advancing the state of the art or increasing knowledge and understanding. ARO has primary responsibility for ARL's extramural basic research programs, with specific research interests as described in Part II.A.2. The ARL Directorates, while having primary responsibility for ARL's in-house research programs, also manage select extramural basic research programs. The research interests of the Directorates are described in Part II.A.1. Although ARL Directorates will consider funding proposals for extramural research programs, they can fund only a modest number of proposals in a single fiscal year.

This Funding Opportunity Announcement (FOA) issued by the Office of Behavioral and Social Sciences Research (OBSSR) and the National Cancer Institute (NCI), the National Heart, Lung, and Blood Institute (NHLBI), the National Institute on Aging (NIA), the National Institute on Alcohol Abuse and Alcoholism (NIAAA), the National Institute of Biomedical Imaging and Bioengineering (NIBIB), the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), the National Institute of Dental and Craniofacial Research (NIDCR), the National Institute of Environmental Health Sciences (NIEHS), the National Institute of General Medical Sciences (NIGMS), the National Institute of Mental Health (NIMH), and the National Institute of Nursing Research (NINR) at the National Institutes of Health, encourages Research Project Grant (R01) applications from institutions/organizations that propose to develop basic and applied projects utilizing systems science methodologies relevant to human behavioral and social sciences and health. This FOA is intended to encourage a broader scope of topics to be addressed with systems science methodologies, beyond those encouraged by existing open FOAs. Research projects applicable to this FOA are those that are either applied or basic in nature (including methodological development), have a human behavioral and/or social science focus, and feature systems science methodologies

The National Center for Science and Engineering Statistics (NCSES) of the National Science Foundation (NSF) is one of the thirteen principal federal statistical agencies within the United States. It is responsible for the collection, acquisition, analysis, reporting and dissemination of objective, statistical data related to the science and engineering enterprise in the United States and other nations that is relevant and useful to practitioners, researchers, policymakers and the public. NCSES uses this information to prepare a number of statistical data reports as well as analytical reports including the National Science Board's biennial report, Science and Engineering (S&E) Indicators, and Women, Minorities and Persons with Disabilities in Science and Engineering. The Center would like to enhance its efforts to support analytic and methodological research in support of its surveys, and to engage in the education and training of researchers in the use of large-scale nationally representative datasets. NCSES welcomes efforts by the research community to use NCSES data for research on the science and technology enterprise, to develop improved survey methodologies for NCSES surveys, to create and improve indicators of S&T activities and resources, and strengthen methodologies to analyze and disseminate S&T statistical data. To that end, NCSES invites proposals for individual or multi-investigator research projects, doctoral dissertation improvement awards, workshops, experimental research, survey research and data collection and dissemination projects under its program for Research on the Science and Technology Enterprise: Statistics and Surveys.

The Division of Mathematical Sciences (DMS) in the Directorate for Mathematical and Physical Sciences (MPS) at the National Science Foundation (NSF) and the National Library of Medicine (NLM) at the National Institutes of Health (NIH) plan to support the development of innovative and transformative mathematical and statistical approaches to address important data-driven biomedical and health challenges. The rationale for this interagency collaboration is that significant advances may be expected as the result of continued NSF investments in foundational research in mathematics and statistics as well as inter- and multi-disciplinary research and training at the intersection of the quantitative/computational sciences and domain sciences, while NIH benefits from the enhancement of biomedical data science with new approaches that strengthen the reproducibility of biomedical research and support open science.

The Division of Mathematical Sciences (DMS) in the Directorate for Mathematical and Physical Sciences (MPS) at the National Science Foundation (NSF) and the National Library of Medicine (NLM)at the National Institutes of Health (NIH)plan to support the development of innovative and transformative mathematical and statistical approaches to address important data-driven biomedical and health challenges. The rationale for this interagency collaboration is that significant advances may be expected as the result of continued NSF investments in foundational research in mathematics and statistics as well as inter- and multi-disciplinary research and training at the intersection of the quantitative/computational sciences and domain sciences, while NIH benefits from the enhancement of biomedical data science with new approaches that strengthen the reproducibility of biomedical research and support open science.

The AHA is interested in the science community exploring all aspects of prevention, which can assist the AHA in reaching its 2020 Goals and overall mission of building healthier lives free of cardiovascular disease and stroke. To that end, the AHA pursues research from the basic, clinical and population sciences. This RFA will require that each submission have an overall application from the Center Director, as well as three proposals from project Principal Investigators: One proposal addressing basic science discovery in prevention One proposal addressing clinical science discovery in prevention One proposal addressing population science discovery in prevention A Center application can comprise projects from more than one institution, as long as there is a named sponsoring institution, where the Center Director is located and will manage the oversight and financial responsibilities. Thus, applications should convey how these different areas of science will collaborate, both in their science discoveries and through joint team communication and integration. 

To analyze and communicate complex scientific topics is more than just a profession - it is an art.  Medical science journalism is no exception. Accordingly, launching a career as science journalist proves to be an arduous endeavor. To help recognize emerging medical science journalists, Germany's most read medical journal Deutsches Ärzteblatt, the European Union of Science Journalists' Associations (EUSJA), and the World Health Summit (WHS) will grant the "Next Generation of Science Journalists" Award for the second time. The top selected five young professionals will be invited to participate in the WHS 2013 and experience a unique international networking and learning opportunity. This provides a career head-start as the annual World Health Summit attracts some 1000 high-ranking participants from all health-related sectors - from Nobel Prize laureates to CEOs and future leaders. Additionally, each winner will receive 500 Euro to recompense travel expenses.

The Presidential Awards for Excellence in Science, Mathematics, and Engineering Mentoring (PAESMEM) is a Presidential award established by the White House in 1995. The purpose of the award is to recognize U.S. citizens or permanent residents and U.S. organizations that have demonstrated excellence in mentoring individuals from groups that are underrepresented in science, technology, engineering, and mathematics (STEM) education and workforce. Groups that are underrepresented in STEM include women, people with disabilities, underrepresented racial and ethnic minorities, as well as individuals from low socio-economic backgrounds and some geographic regions such as urban and rural areas. The PAESMEM program is administered by the National Science Foundation (NSF) on behalf of the White House Office of Science and Technology Policy (OSTP). Nominations, including self-nominations, are invited for Individual and Organizational PAESMEM awards. Individuals and organizations in all public and private sectors are eligible including industry, academia, primary and secondary education, military and government, non-profit organizations, and foundations. Nominations are encouraged from all geographical regions in the U.S., its territories or possessions, particularly jurisdictions designated by Congress under NSF's Experimental Program to Stimulate Competitive Research (EPSCoR).

The purpose of this Funding Opportunity Announcement (FOA) is to encourage projects to generate fundamental knowledge of affective processes. Basic affective science projects should have key downstream consequences for single (e.g., genetic testing consent) and multiple (e.g., adherence to oral chemotherapy regimen) event decisions and behaviors across the cancer prevention and control continuum. The FOA is expected to encourage scientific disciplines that have not traditionally conducted cancer research such as affective and cognitive neuroscience, decision science, and consumer science to elucidate perplexing and understudied problems in basic affective and decision sciences with promise of having downstream implications for cancer prevention and control science.

The purpose of the NIH Summer Research Experience Program (referred to as the Summer Research Program) is to provide a high quality research experience for high school and college students and for science teachers during the summer academic break. The NIH expects that such programs will: help attract young students to careers in science; provide opportunities for college students to gain valuable research experience to help prepare them for graduate school; and enhance the skills of science teachers and enable them to more effectively communicate the nature of the scientific process to their students. The programs would also contribute to enhancing overall science literacy. Summer Research Programs that expand and complement existing summer educational and training programs are encouraged.

The goal of theBiomedical Engineering(BME)program is to provide research opportunities to develop novel ideas into discovery-level and transformative projects that integrate engineering and life sciences in solving biomedical problems that serve humanity in the long-term. BME projects must be at the interface of engineering and life sciences, and advance both engineering and life sciences. The projects should focus on high impact transformative methods and technologies. Projects should include methods, models and enabling tools of understanding and controlling living systems; fundamental improvements in deriving information from cells, tissues, organs, and organ systems; new approaches to the design of structures and materials for eventual medical use in the long-term; and novel methods for reducing health care costs through new technologies. The long-term impact of the projects can be related to fundamental understanding of cell and tissue function, effective disease diagnosis and/or treatment, improved health care delivery, or product development.

The goal of theBiomedical Engineering(BME)program is to provide research opportunities to develop novel ideas into discovery-level and transformative projects that integrate engineering and life sciences in solving biomedical problems that serve humanity in the long-term. BME projects must be at the interface of engineering and life sciences, and advance both engineering and life sciences. The projects should focus on high impact transformative methods and technologies. Projects should include methods, models and enabling tools of understanding and controlling living systems; fundamental improvements in deriving information from cells, tissues, organs, and organ systems; new approaches to the design of structures and materials for eventual medical use in the long-term; and novel methods for reducing health care costs through new technologies. The long-term impact of the projects can be related to fundamental understanding of cell and tissue function, effective disease diagnosis and/or treatment, improved health care delivery, or product development.

The National Institute of General Medical Sciences (NIGMS) invites applications for Centers of Biomedical Research Excellence (COBRE) from investigators at biomedical research institutions that award doctoral degrees in the health sciences or sciences related to health or at independent biomedical research institutes with ongoing biomedical research programs funded by the NIH or other federal agencies within Institutional Development Award (IDeA) eligible states. The objectives of the COBRE initiative is to strengthen an institution's biomedical research infrastructure through the establishment of a thematic multi-disciplinary center and to enhance the ability of investigators to compete independently for complementary National Institutes of Health (NIH) individual research grants or other external peer-reviewed support. COBRE awards are supported through the IDeA Program, which aims to foster health-related research by increasing the competitiveness of investigators at institutions located in states with historically low aggregate success rates for grant awards from the NIH.

The National Institute of General Medical Sciences (NIGMS) invites applications for Centers of Biomedical Research Excellence (COBRE) from investigators at biomedical research institutions that award doctoral degrees in the health sciences or sciences related to health or at independent biomedical research institutes with ongoing biomedical research programs funded by the NIH or other federal agencies within Institutional Development Award (IDeA) eligible states. The objectives of the COBRE initiative is to strengthen an institution's biomedical research infrastructure through the establishment of a thematic multi-disciplinary center and to enhance the ability of investigators to compete independently for complementary National Institutes of Health (NIH) individual research grants or other external peer-reviewed support. COBRE awards are supported through the IDeA Program, which aims to foster health-related research by increasing the competitiveness of investigators at institutions located in states with historically low aggregate success rates for grant awards from the NIH.

This FOA invites applications for the Microphysiological Systems (MPS) for Disease Modeling and Efficacy Testing Program to develop highly reproducible and translatable in vitro models for preclinical efficacy studies through discovery and validation of translatable biomarkers, development of standardized methods for preclinical efficacy testing and definitive efficacy testing of candidate therapeutics using best practices and rigorous study design. An essential feature will be a multidisciplinary approach that brings together experts in bioengineering, microfluidics, material science, "omic" sciences, computational biology, disease biology, pathology, electrophysiology, pharmacology, biostatistics and clinical science.

This FOA invites applications for the Microphysiological Systems (MPS) for Disease Modeling and Efficacy Testing Program to develop highly reproducible and translatable in vitro models for preclinical efficacy studies through discovery and validation of translatable biomarkers, development of standardized methods for preclinical efficacy testing and definitive efficacy testing of candidate therapeutics using best practices and rigorous study design. An essential feature will be a multidisciplinary approach that brings together experts in bioengineering, microfluidics, material science, "omic" sciences, computational biology, disease biology, pathology, electrophysiology, pharmacology, biostatistics and clinical science.

The long-range goal of the Enriched Doctoral Training in the Mathematical Sciences (EDT) program is to strengthen the nation's scientific competitiveness by increasing the number of well-prepared U.S. citizens, nationals, and permanent residents who pursue careers in the mathematical sciences and in other professions in which expertise in the mathematical sciences plays an increasingly important role.  The EDT program will achieve this by supporting efforts to enrich research training in the mathematical sciences at the doctoral level by preparing Ph.D. students to recognize and find solutions to mathematical challenges arising in other fields and in areas outside today's academic setting.  Graduate research training activities supported by EDT will prepare participants for a broader range of mathematical opportunities and career paths than has been traditional in U.S. mathematics doctoral training.

The 2016 U.S. Advancing Science through Pfizer: Investigator Research Exchange (ASPIRE) Hemophilia Research Awards Program is a competitive grants program that reflects the commitment of Pfizer Hemophilia to support ongoing basic science and clinical investigation in hemophilia A and B. Ongoing basic science research and clinical research are critical to deepen understanding of disease mechanisms and to ensure advancement of management strategies for hemophilia A and hemophilia B and their related comorbidities. In an era of increased competition for research funding, the 2016 U.S. ASPIRE Hemophilia Research Awards Program is designed to support laboratory and clinical research in pathogenesis, complications, management, and clinical outcomes of hemophilia A and B.

The 2016 U.S. Advancing Science through Pfizer: Investigator Research Exchange (ASPIRE) Hemophilia Research Awards Program is a competitive grants program that reflects the commitment of Pfizer Hemophilia to support ongoing basic science and clinical investigation in hemophilia A and B. Ongoing basic science research and clinical research are critical to deepen understanding of disease mechanisms and to ensure advancement of management strategies for hemophilia A and hemophilia B and their related comorbidities. In an era of increased competition for research funding, the 2016 U.S. ASPIRE Hemophilia Research Awards Program is designed to support laboratory and clinical research in pathogenesis, complications, management, and clinical outcomes of hemophilia A and B.

The purpose of the NHLBI Career Pathway to Independence in Blood Science Award for Physician Scientists (K99) is to increase and maintain a stong cohort of new and talented, NHLBI supported, independent investigators in blood science. This program is designed to facilitate a timely transition of outstanding blood science researchers with a clinical doctorate degree from mentored research positions to independent, tenure-track or equivalent faculty positions. Applicants who receive this award may submit an application for R00 funding, in the separate funding opportunity associated with this program, to help awardees to launch competitive, independent research careers in blood science. This Funding Opportunity Announcement (FOA) is designed specifically for applicants proposing to serve as the lead investigator of an independent clinical trial, a clinical trial feasibility study, or a separate ancillary clinical trial , as part of their research and career development. Applicants not planning an independent clinical trial, or proposing to gain research experience in a clinical trial led by another investigator, must apply to companion FOA (RFA-HL-20-001).

The purpose of the NHLBI Career Pathway to Independence in Blood Science Award for Physician Scientists (K99) is to increase and maintain a strong cohort of new and talented, NHLBI supported, independent investigators in blood science. This program is designed to facilitate a timely transition of outstanding blood science researchers with a clinical doctorate degree from mentored research positions to independent, tenure-track or equivalent faculty positions. Applicants who receive this award may submit an application for R00 funding, in the separate funding opportunity associated with this program, to help awardees launch competitive, independent research careers in blood science.

The FY19 PCRP Translational Science Award mechanism supports translational research that will develop promising ideas in prostate cancer into clinical applications. Translational research may be defined as an integration of basic science and clinical observations. Observations that drive a research idea may originate from a laboratory discovery, population-based studies, or a clinician's firsthand knowledge of patient care. The ultimate goal of translational research is to move a concept or observation forward into clinical application. As such, applications must include a detailed transition plan that articulates the pathway to moving the project's findings to the next phase of development after successful completion of the award, and how the Principal Investigator (PI) will continue advancing the research toward making a clinical impact, even if clinical impact is not an immediate outcome. However, PIs should not view translational research as a one-way continuum from bench to bedside. The research plan must involve a reciprocal flow of ideas and information between basic and clinical science. The potential impact of the research is expected to be significant and go beyond an incremental advance. Proposed projects may include basic, translational, population science, and/or clinical research, but must demonstrate clinical relevance.