The overall goal of the Structural and Architectural Engineering and Materials (SAEM) program is to enable sustainable buildings and other structures that can be continuously occupied and/or operated during the structure's useful life. The SAEM program supports fundamental research for advancing knowledge and innovation in structural and architectural engineering and materials that promotes a holistic approach to analysis and design, construction, operation, maintenance, retrofit, and repair of structures. For buildings, all components including the foundation-structure-envelope (the façade, curtain-wall and roofing) and interior systems, are of interest to the program. Research in new engineering concepts and design paradigms for buildings that have significantly reduced dependence and interdependence on municipal infrastructure through, for example, self-hydrating (closed-loop water system) and self-heating-cooling-ventilating (energy usage) is encouraged. In addition, the program targets research in the building systems that are reconfigurable for rapid construction, disassembly and disposal, are reliable and resilient, and are less complex. Research topics of interest for sustainable structures include the following: strategies for structures that over their lifecycle are cost-effective, make efficient use of resources and energy, and incorporate sustainable structural and architectural materials; mitigation of deterioration due to fatigue and corrosion; serviceability related to large deflections and vibrations; and advances in physics-based computational modeling and simulation.

This solicitation seeks proposals for the development and/or demonstration of new technologies and capabilities for small spacecraft by U.S. colleges and universities in collaboration with NASA. Projects may be for ground-based technology development or development of spacecraft or payloads for suborbital, balloon or orbital space flight technology demonstrations. Proposed projects must develop or demonstrate technologies or new capabilities for small spacecraft that support NASA's missions in science, exploration, space operations, or aeronautics. Proposals must address one of the following specific topics: Topic 1: Enhanced Power Generation and Storage, Topic 2: Cross-linking Communications Systems, Topic 3: Relative Navigation for Multiple Small Spacecraft, and Topic 4: Instruments and Sensors for Small Spacecraft Science Missions. Cooperative Agreements will be issued to the proposing college or university partner. The cooperative agreement award resulting from this appendix will be between NASA and the primary proposing U.S. college or university. Cost sharing is not required. Maximum period of performance is two years, with continuation to Year 2 contingent on progress achieved during Year 1 and the availability of funds. Participation is limited to U.S. college and university teams, including undergraduate and/or graduate students. Projects must include student participation. The Principal Investigator (PI) submitting the proposal shall be affiliated with a U.S. college or university. All proposals must be submitted electronically through NSPIRES by an Authorized Organizational Representative (AOR). Detailed submission instructions are provided in the SpaceTech-REDDI-2016 NRA, as well as the Guidebook for Proposers Responding to a NASA Research Announcement (NRA) or Cooperative Agreement Notice (CAN) (Edition January 2015).

The Technology Validation and Start-Up Fund (the "Program") provides grants to transition technology from Ohio research institutions into the marketplace through Ohio start-up companies. Ohio research institutions may apply for funding for validation (e.g. viability testing, prototyping, etc.) of their unlicensed technologies. Ohio start-up companies may apply for funding to advance towards commercialization a technology they intend to license from an Ohio research institution.

The Broadening Participation in Engineering (BPE) Program is a Directorate-wide initiative dedicated to supporting the development of a diverse and well-prepared engineering workforce. Across every educational juncture (e.g., elementary, secondary, and postsecondary levels), efforts to improve engineering interests, preparation, connections, experiences, and opportunities among underrepresented groups is of major importance to BPE. BPE is interested in funding projects that bring together multiple groups (e.g., school districts, community colleges, engineering schools, industry, philanthropy, government, etc.) and offer the greatest return on investment by producing outcomes that are scalable, sustainable, and applicable to various contexts, settings, and demographics within the engineering enterprise. For example, it is interested research projects thathelp us to analyze and understandthe problem of insufficient interest and poorly sustained participation in engineering across underrepresented demographic groups; insignificant preparation and scarce opportunities for members of underrepresented demographic groups to learn meaningful, relevant engineering and other STEM-related content; insufficient access to support systems and social networks that raises career awareness about different engineering pathways among underrepresented groups; and structural inequalities and biases within educational and workforce systems that may influence engineering persistence.

Leidos will match high-scoring, unfunded National Institutes of Health (NIH) proposals with private biomedical foundations and/or industries seeking to fund promising research. Foundations will have access to peer-reviewed research proposals that directly relate to their funding priorities, industry will have access to a rich pipeline of early stage and translational research proposals that align with its priorities, while applicants with strong research proposals will be provided with a second opportunity to secure funding. The foundations, industries, applicants, and NIH all will benefit from this synergy.

The overall goal of the Intramural NIGMS Postdoctoral Research Associate (PRAT) program is to help ensure that a diverse pool of highly trained scientists is available in appropriate scientific disciplines to address the Nation's biomedical research needs.

With this Dear Colleague Letter, NSF is providing advance notice of a change in the eligibility of prospective applicants to the Graduate Research Fellowship Program (GRFP) to allow the community to plan accordingly. Effective as of the 2017 competition (Fall 2016 deadlines), NSF will limit graduate students to only one application to the GRFP, submitted either in the first year or in the second year of graduate school. No change is made to the eligibility of undergraduates, of bachelor's degree holders without any graduate study, or of individuals who have had an interruption in graduate study of at least two consecutive years.

The ARI program addresses the security, prevention and protection per the PPD-8 by seeking novel cross-cutting research that will enhance national security's capability to detect and interdict nuclear or radiological material outside of regulatory control, and otherwise help prevent nuclear terrorism or radiological attacks.

Cell-based therapies, especially immune cells, have the potential to revolutionize human healthcare in various different contexts, including cancer and personalized medicine. For example, CAR (Chimeric antigen receptor) T-cell therapy for cancer requires modification, in vitro culture and expansion of human T-cells.   Manufacturing of therapeutic cells as the end product presents major engineering challenges.  New therapies and cell-based products depend critically on the development of robust, reliable and reproducible biomanufacturing technologies.

The goal of a Bioengineering Research Partnership (BRP) is to drive the development and speed the adoption of promising tools and technologies that can address important biomedical problems for which insufficient or no solutions exist.  The use of engineering principles is encouraged to establish these tools and technologies as robust, well-characterized solutions that fulfill an unmet need. A synergistic partnership between engineering and the life, physical, and computational sciences is also encouraged, where the unique skills of each discipline combine to enhance our understanding of life science processes or the practice of medicine. The purpose of this FOA is to encourage BRP applications that: 1) establish a robust engineering solution to a problem in biomedical research or the practice of medicine; 2) develop a strategic alliance of multidisciplinary partners based on a well-defined leadership plan; and 3) realize a specific endpoint within 5-10 years based on a detailed plan with a timeline and quantitative milestones.

The Office of Energy Efficiency and Renewable Energy (EERE), within the U.S. Department of Energy (DOE), invests in high-risk, high-value research, development and deployment in energy efficiency and renewable energy technologies. EERE, through the Building Technologies Office (BTO) seeks to develop technologies, techniques, and tools for making buildings more energy efficient, productive, and affordable. BTO's strategic goal is to significantly improve the energy efficiency of new and existing buildings to reduce national energy demand and allow the nation to work toward greater energy independence and a cleaner environment. This Funding Opportunity Announcement (FOA) is targeted specifically at research to increase energy savings and reduce consumer bills through improved compliance with building energy codes. The first and largest topic area for this FOA is to develop and test a methodology for identifying the commercial energy code requirements that can provide the maximum cost-effective energy and cost savings through increased compliance. The methodology will be tested in selected building types and climate zones. Quantifying those savings will create the foundations of a business case for private investors, particularly utilities, to fund programs aimed at increasing compliance. The empirical data to support such an investment does not currently exist.

The EISENHOWER GRADUATE FELLOWSHIP (provides funding for the pursuit of Masters or Doctorate Degrees in transportation related discipline. The program objectives are: 1) to attract the nation's brightest minds to the field of transportation, 2) to enhance the careers of transportation professionals by encouraging them to seek advanced degrees, and, 3) to retain top talent in the transportation industry of the United States. The Program is intended to bring innovation and enhance the breadth and scope of knowledge of the entire transportation community in the United States. The Eisenhower Graduate Fellowship Program encompasses all modes of transportation.

The Fixing America's Surface Transportation Act (FAST Act; P. L. 114-94, December 4, 2015) authorizes the Secretary of Transportation to make grants to eligible non-profit institutions of higher education to establish and operate University Transportation Centers (UTCs or Centers). Non-profit institutions of higher education may include qualifying two-year institutions (20 U.S.C. § 1001(a)).  The Office of the Assistant Secretary for Research and Technology (OST-R) of the U.S. Department of Transportation (US DOT) will manage the UTC Program.

The anticipated contract will be required to provide full environmental engineering services for the National Guard installations across the CONUS and its surrounding territories.

The 711th Human Performance Wing intends to solicit White Papers under this announcement for Aerospace Medicine, Clinical Research, Human Performance Research, and Expeditionary Medicine for innovative and state-of-the-art research to enhance the following fields of En Route Care, Expeditionary Medicine, Force Health Protection, Human Performance and Systems Integration, and Operational Medicine.

The National Science Foundation (NSF) seeks to develop and nurture a national innovation ecosystem that builds upon research to guide the output of scientific discoveries closer to the development of technologies, products and processes that benefit society.

One of JDRF's therapeutic goals is to restore beta cell function in type 1 diabetes (T1D) by replacement/transplantation of beta cells/islets. Pancreatic islet transplantation has been efficacious in selected patients in improving metabolic control and quality of life, and in preventing severe hypoglycemia in patients with medically unstable T1D. Despite improvements in cadaveric pancreas procurement, islet isolation, and islet purification, major scientific and technical challenges remain that must be addressed before beta cell replacement could be widely incorporated into the clinical management of established T1D; examples include serious side effects from chronic immunosuppression and the insufficient human islet supply from cadaveric pancreata. JDRF's role is to enable the scientific community to address these challenges with the ultimate goal of developing safe and effective beta cell replacement approaches available to large numbers of individuals with T1D.

One of JDRF's therapeutic goals is to restore beta cell function in type 1 diabetes (T1D) by replacement/transplantation of beta cells/islets. Pancreatic islet transplantation has been efficacious in selected patients in improving metabolic control and quality of life, and in preventing severe hypoglycemia in patients with medically unstable T1D. Despite improvements in cadaveric pancreas procurement, islet isolation, and islet purification, major scientific and technical challenges remain that must be addressed before beta cell replacement could be widely incorporated into the clinical management of established T1D; examples include serious side effects from chronic immunosuppression and the insufficient human islet supply from cadaveric pancreata. JDRF's role is to enable the scientific community to address these challenges with the ultimate goal of developing safe and effective beta cell replacement approaches available to large numbers of individuals with T1D.

The objective is to solicit and competitively award research projects to develop advanced energy systems that will make substantial progress toward enabling cost-competitive, fossil-based power generation with near-zero emissions

The objective is to solicit and competitively award research projects to develop advanced energy systems that will make substantial progress toward enabling cost-competitive, fossil-based power generation with near-zero emissions

This FOA relates to one of the initiatives of the SPARC (Stimulating Peripheral Activity to Relieve Conditions) Common Fund program titled: Use of Existing Market-Approved Technology for New Market Indications. By establishing effective public-private partnerships, this SPARC initiative allows supported investigators to have access to existing neuromodulation technology to explore new indications. A number of device manufacturers have entered into partnership agreements with the NIH to make their neuromodulation technology, consisting of implantable devices with recording and/or stimulation capabilities, available to SPARC's supported clinical investigators (see Device Portal for a list of companies and available technologies). The specific goal of this FOA is to promote the pre-clinical development of these technologies, in support of a new market indication, towards enabling an Investigational Device Exemption (IDE) submission for a future pilot clinical study. Awarded projects of this FOA that fully reach their pre-clinical testing milestones will be eligible for further support, subject to a subsequent FOA, to conduct a pilot clinical study. The expectation is that these pilot clinical studies will provide the initial proof-of-principle demonstrations in humans that will motivate the additional studies needed in pursuing FDA approval as a labeled indication.

This FOA relates to one of the initiatives of the SPARC (Stimulating Peripheral Activity to Relieve Conditions) Common Fund program titled: Use of Existing Market-Approved Technology for New Market Indications. By establishing effective public-private partnerships, this SPARC initiative allows supported investigators to have access to existing neuromodulation technology to explore new indications. A number of device manufacturers have entered into partnership agreements with the NIH to make their neuromodulation technology, consisting of implantable devices with recording and/or stimulation capabilities, available to SPARC's supported clinical investigators (see Device Portal for a list of companies and available technologies). The specific goal of this FOA is to promote the pre-clinical development of these technologies, in support of a new market indication, towards enabling an Investigational Device Exemption (IDE) submission for a future pilot clinical study. Awarded projects of this FOA that fully reach their pre-clinical testing milestones will be eligible for further support, subject to a subsequent FOA, to conduct a pilot clinical study. The expectation is that these pilot clinical studies will provide the initial proof-of-principle demonstrations in humans that will motivate the additional studies needed in pursuing FDA approval as a labeled indication.

NIST is soliciting applications for financial assistance for Fiscal Year 2016 (FY16) within the following NIST Laboratory grant programs: (1) the Material Measurement Laboratory (MML) Grant Program; (2) the Physical Measurement Laboratory (PML) Grant Program; (3) the Engineering Laboratory (EL) Grant Program; (4) the Fire Research (FR) Grant Program; (5) the Information Technology Laboratory (ITL) Grant Program; (6) the Communications Technology Laboratory (CTL) Grant Program; (7) the NIST Center for Neutron Research (NCNR) Grant Program; (8) the Center for Nanoscale Science and Technology (CNST) Grant Program; (9) the Special Programs Office (SPO) Grant Program; (10) the Standards Coordination Office (SCO) Grant Program; (11) the International and Academic Affairs Office (IAAO) Grant Program; and (12) the Associate Director for Laboratory Programs (ADLP) Grant Program.

NIST is soliciting applications for financial assistance for Fiscal Year 2016 (FY16) within the following NIST Laboratory grant programs: (1) the Material Measurement Laboratory (MML) Grant Program; (2) the Physical Measurement Laboratory (PML) Grant Program; (3) the Engineering Laboratory (EL) Grant Program; (4) the Fire Research (FR) Grant Program; (5) the Information Technology Laboratory (ITL) Grant Program; (6) the Communications Technology Laboratory (CTL) Grant Program; (7) the NIST Center for Neutron Research (NCNR) Grant Program; (8) the Center for Nanoscale Science and Technology (CNST) Grant Program; (9) the Special Programs Office (SPO) Grant Program; (10) the Standards Coordination Office (SCO) Grant Program; (11) the International and Academic Affairs Office (IAAO) Grant Program; and (12) the Associate Director for Laboratory Programs (ADLP) Grant Program.