Understanding the dynamic activity of neural circuits is central to the NIH BRAIN Initiative. Although invention and proof-of-concept testing of new technologies are a key component of the BRAIN Initiative, to achieve their potential these technologies must also be optimized through feedback from end-users in the context of the intended experimental use. This FOA seeks applications for the optimization of existing and emerging technologies and approaches that have potential to address major challenges associated with recording and manipulating neural activity, at or near cellular resolution, at multiple spatial and temporal scales, in any region and throughout the entire depth of the brain. This FOA is intended for the iterative refinement of emergent technologies and approaches that have already demonstrated their transformative potential through initial proof-of-concept testing, and are appropriate for accelerated development of hardware and software while scaling manufacturing techniques towards sustainable, broad dissemination and user-friendly incorporation into regular neuroscience practice. Proposed technologies should be compatible with experiments in behaving animals, and should include advancements that enable or reduce major barriers to hypothesis-driven experiments. Technologies may engage diverse types of signaling beyond neuronal electrical activity for large-scale analysis, and may utilize any modality such as optical, electrical, magnetic, acoustic or genetic recording/manipulation. Applications that seek to integrate multiple approaches are encouraged. Applications are expected to integrate appropriate domains of expertise, including where appropriate biological, chemical and physical sciences, engineering, computational modeling and statistical analysis. Also listed under R01

This Funding Opportunity Announcement (FOA) seeks applications for the design and development of technologies to monitor health or deliver care in a real-time, accessible, effective, and minimally obtrusive way for older adults with a chronic heart, lung, blood, or sleep (HLBS) condition. These technologies may be novel sensor or monitoring systems, home-use point-of-care devices, home or mobile therapy or rehabilitation tools, or information systems and should have the goal of fostering healthy and independent living for aging adults with HLBS conditions. The development of such technologies should incorporate specific human factors for aging adults including disabilities, mild impairments, as well as chronic HLBS conditions. Technology usability for these populations must be incorporated early in the development of the design. Usability considerations include but are not limited to patient-facing displays, hearing and visual impairments, tactile limitations, literacy, and design preferences between men and women. These improvements in technology design could yield more accurate and earlier detection of changes that may interfere with healthy and independent living for older adults.

The National Council of Teachers of Mathematics works to ensure equitable mathematics learning of the highest quality for all students through vision, leadership, the professional development of teachers, and research. To that end, NCTM is accepting applications to its Connecting Mathematics to Other Subject Areas Grants for Grades 9-12 Teachers program, which supports senior high classroom materials or lessons that connect mathematics to other areas of study. For the 2019-20 school year, grants of up to $4,000 each will be awarded to persons currently teaching mathematics in grades 9-12. Materials may be in the form of books, visual displays, computer programs or displays, slide shows, videotapes, or other appropriate media. The focus of these materials should be on showing the connectivity of mathematics to other fields and/or the world around us.

Although invention and proof-of-concept testing of new technologies are a key component of the BRAIN Initiative, to achieve their potential these technologies must also be optimized through feedback from end-users in the context of the intended experimental use. This seeks applications for the optimization of existing and emerging technologies and approaches that have potential to address major challenges associated with recording and manipulating neural activity, at or near cellular resolution, at multiple spatial and temporal scales, in any region and throughout the entire depth of the brain. This FOA is intended for the iterative refinement of emergent technologies and approaches that have already demonstrated their transformative potential through initial proof-of-concept testing, and are appropriate for accelerated development of hardware and software while scaling manufacturing techniques towards sustainable, broad dissemination and user-friendly incorporation into regular neuroscience practice. Proposed technologies should be compatible with experiments in behaving animals, and should include advancements that enable or reduce major barriers to hypothesis-driven experiments. Technologies may engage diverse types of signaling beyond neuronal electrical activity for large-scale analysis, and may utilize any modality such as optical, electrical, magnetic, acoustic or genetic recording/manipulation. Applications that seek to integrate multiple approaches are encouraged. Applications are expected to integrate appropriate domains of expertise, including where appropriate biological, chemical and physical sciences, engineering, computational modeling and statistical analysis.

Understanding the dynamic activity of neural circuits is central to the NIH BRAIN Initiative. This FOA seeks applications for proof-of-concept testing and development of new technologies and novel approaches for largescale recording and manipulation of neural activity to enable transformative understanding of dynamic signaling in the nervous system. In particular, we seek exceptionally creative approaches to address major challenges associated with recording and manipulating neural activity, at or near cellular resolution, at multiple spatial and/or temporal scales, in any region and throughout the entire depth of the brain. It is expected that the proposed research may be high-risk, but if successful could profoundly change the course of neuroscience research. Proposed technologies should be compatible with experiments in behaving animals, and should include advancements that enable or reduce major barriers to hypothesis-driven experiments. Technologies may engage diverse types of signaling beyond neuronal electrical activity for large-scale analysis, and may utilize any modality such as optical, electrical, magnetic, acoustic or genetic recording/manipulation. Applications that seek to integrate multiple approaches are encouraged. Where appropriate, applications are expected to integrate appropriate domains of expertise, including biological, chemical and physical sciences, engineering, computational modeling and statistical analysis.

A vigorous Mid-Scale Innovations Program (MSIP) was recommended by the 2010 Astronomy and Astrophysics Decadal Survey, citing "many highly promising projects for achieving diverse and timely science." As described in this solicitation, the Division of Astronomical Sciences has established a mid-scale program to support a variety of astronomical activities within a cost range up to $30M. This program will be formally divided into four subcategories: 1) limited term, self-contained science projects; 2) longer term mid-scale facilities; 3) development investments for future mid-scale and large-scale projects; and 4) community open access capabilities. The MSIP will emphasize both strong scientific merit and a well-developed plan for student training and involvement of a diverse workforce in instrumentation, facility development, or data management.

The U.S. Department of Energy seeks to understand the key technical and other barriers that may prevent long-term access to low-cost water supplies that could be best addressed through challenges and prize competitions. For the purposes of this Request for Information (RFI), challenges and prize competitions are tools and approaches the Federal government and others can use to engage a broad range of stakeholders, including the general public, in developing solutions to difficult problems. Challenges and prize competitions rely on competitive structures to drive innovation among participants and usually offer rewards (financial and/or other) to winners and/or finalists. DOE may use the information provided through this RFI to develop challenges and prize competitions to address key water issues. This RFI is not designed to solicit input on DOE's broader R&D efforts on affordable water. The purpose of this Request for Information (RFI) is to gather feedback from stakeholders prior to DOE potentially issuing a Funding Opportunity Announcement (FOA). This RFI is not a FOA; therefore, DOE is not accepting applications at this time. All responses to this RFI must be provided as an attachment (in Microsoft Word format) to an e-mail message addressed to waterprizerfi@ee.doe.gov. Responses must be received no later than 5:00 pm EDT on May 14, 2018. The full content of the announcement can be found on the EERE Exchange website at https://eere-exchange.energy.gov/

CISE's Division of Computing and Communication Foundations (CCF) supports research and education projects that develop new knowledge in three core programs: The Algorithmic Foundations (AF) program; The Communications and Information Foundations (CIF) program; and The Software and Hardware Foundations (SHF) program. Proposers are invited to submit proposals in three project classes, which are defined as follows: Small Projects - up to $500,000 total budget with durations up to three years; Medium Projects - $500,001 to $1,200,000 total budget with durations up to four years; and Large Projects - $1,200,001 to $3,000,000 total budget with durations up to five years.

The NICS Improvement Amendments Act of 2007, Pub. L. 110-180 (NIAA or the Act), was signed into law on January 8, 2008, in the wake of the April 2007 shooting tragedy at Virginia Tech. The Virginia Tech shooter was able to purchase firearms from a Federal Firearms Licensee (FFL) because information about his prohibiting mental health history was not available to the NICS, and the system was therefore unable to deny the transfer of the firearms used in the shootings. The NIAA seeks to address the gap in information available to NICS about such prohibiting mental health adjudications and commitments, and other prohibiting factors. Filling these information gaps will better enable the system to operate as intended to keep guns out of the hands of persons

NIJ is interested to fund a single evaluator that will have the capabilities to assess the effectiveness of a few promising technologies that can enhance safety within K-12 schools. Evaluations should consider the school environment and use cases as well as the kinds of data that might be collected or used as a result of the technology intervention. Applicants are encouraged to explore technologies that have worked for use cases in other ecosystems that may translate well to the K-12 school environment.

The National Science Foundation (NSF) seeks to further develop and nurture a national innovation ecosystem that builds upon fundamental research to guide the output of scientific discoveries closer to the development of technologies, products, processes and services that benefit society. The goal of the program is to dramatically reduce the period of time necessary to bring a promising idea from its inception to widespread implementation. Through this solicitation, NSF is seeking to expand and sustain the network of Innovation Corps (I-CorpsTM) (hereinafter I-Corps) Nodes that work cooperatively to support the development of innovations that will benefit society. NSF plans to build upon the established National Innovation Network (consisting of I-Corps Nodes and Sites) to further support the needs for innovation research, education and training. The interconnected nodes of the network are expected to be diverse in research areas, resources, tools, programs, capabilities, and geographic locations - providing the network with the flexibility to grow or reconfigure as needs arise.

The ERC program is placing greater emphasis on research that leads to societal impact, including convergent approaches, engaging stakeholder communities, and strengthening team formation, in response to the NASEM study recommendations. The ERC program intends to support planning activities leading to convergent research team formation and capacity-building within the engineering community. This planning grant pilot initiative is designed to foster and facilitate the engineering community's thinking about how to form convergent research collaborations. To participate in the upcoming ERC competition, one is not required to submit a planning grant proposal nor to receive a planning grant.

The purpose of this FOA is the rapid and efficient translation of innovative laboratory research findings into therapies, devices or other resources for use by clinicians to treat visual system diseases or disorders. Multidisciplinary teams of scientists and clinicians must focus on generating preclinical data that will lead to the development of biological interventions, such as gene therapy, cell-based therapy, pharmacological approaches, and/or medical devices. The ultimate goal of this program is to make technological, biological and pharmacological resources available to clinicians and their patients. Each project should have a well-defined end-point, achievable within a five-year time frame, of developing a device or treatment for a specific ocular disease.

A major objective of this funding opportunity announcement (FOA) is to invite SBIR applications to foster collaboration between clinical and bioengineering research communities to develop and test safe, accurate, and effective devices for use in neonatal, perinatal, and pediatric care settings. These can be new devices or improvements on existing devices. The studies may range from concept to developmental phases, with a clear commercialization plan to enable healthcare providers to use them in regular clinical care settings in the population, which is the focus of this FOA.

The Chan Zuckerberg Initiative invites applications to join the CZI Neurodegeneration Challenge Network an interdisciplinary collaborative initiative to increase understanding of the fundamental biology of neurodegenerative disorders. Applications are being accepted for two funding mechanisms: Awards are worth $350K total costs per year for three years, for a total of $1.05M (including up to 15% indirect costs). The CZI Neurodegeneration Challenge Network has three goals: (1) to make fundamental advances toward understanding neurodegeneration; (2) to bring new ideas and talent to the field of neurodegeneration; and (3) to encourage a new type of interdisciplinary collaborative research involving scientists, clinicians and engineers

The Office of Fusion Energy Sciences (FES) and the Office of Advanced Scientific Computing Research (ASCR) of the Office of Science (SC), U.S. Department of Energy (DOE), announce their interest in receiving applications from multi-institutional interdisciplinary teams to establish a scientific application partnership under the Scientific Discovery through Advanced Computing (SciDAC) program in the area of runaway electron physics in magnetically confined plasmas. The goal of this FOA is to select applications that can take advantage of today's multi-petascale DOE high-performance computing (DOE HPC) systems to accelerate scientific discovery in a strategically important area of magnetic fusion energy science and address high-priority issues identified in recent community studies.

The Fiscal Year 2019 Air Force Young Investigator Research Program (YIP) intends support for scientists and engineers who have received Ph.D. or equivalent degrees 1 April 2012 or later that show exceptional ability and promise for conducting basic research. The program objective is to foster creative basic research in science and engineering; enhance early career development of outstanding young investigators; and increase opportunities for the young investigator to recognize the Air Force mission and related challenges in science and engineering. Individual awards are made to U.S. institutions of higher education, industrial laboratories, or non-profit research organizations where the principal investigator is employed on a full-time basis and holds a regular position. YIP primary investigators must be a U.S. citizen, national, or permanent resident. Researchers working at a Federally Funded Research and Development Center or DoD Laboratory are not eligible for this competition. Most YIP awards are funded at $150,000 per year for three years, for a total of $450,000. Exceptional proposals will be considered individually for higher funding levels and/or longer duration. Please review the remainder of this announcement for additional information. We anticipate approximately fifty (36) awards under this competition if funds are available.

The landscape of jobs and work is changing at unprecedented speed, driven by the development of new technologies that have moved from the factory floor to an expanding array of knowledge and service occupations. These changes promise benefits to the Nation in the creation of new industries and occupations, increased productivity, opportunity for innovation, and sustained global leadership. But there are risks as well. Technological advances scale back the need for some workers, and in some cases, eliminate job sectors, with consequences to displaced workers who must adapt to emerging new technologies and the changing economy through retraining and reskilling. The Future of Work at the Human-Technology Frontier (FW-HTF) is one of 10 new and far-sighted Big Ideas for Future Investments announced by NSF in 2016.

The mission of the DOE FE Solid Oxide Fuel Cell (SOFC) program is to enable the efficient generation of low-cost electricity for (a) 2nd Generation natural gas-fueled SOFC DG systems and modular, coal-fueled systems and (b) Transformational coal or natural gas-fueled utility-scale systems with carbon capture and sequestration (CCS). The program supports the overarching goals of the Clean Coal and Carbon Management Research Program (CCCMRP) through the collaboration between the R&D that addresses the technical and economic barriers to commercial viability and the development and deployment of SOFC power systems that validate those solutions.

To honor a physicist whose research in an undergraduate setting has achieved wide recognition and contributed significantly to physics and who has contributed substantially to the professional development of undergraduate physics students. The prize consists of a $5,000 stipend to the prize recipient and a separate $5,000 unrestricted grant for the research to the prize recipient's institution. An additional allowance will be provided for travel expenses to the APS meeting at which the prize ceremony will take place and a certificate citing the contributions by the recipient. The prize is presented annually. The prize was established in 1984 by a grant from the Research Corporation for Science Advancement, a private foundation for the advancement of science and technology. The prize will be given to a physics faculty member at an undergraduate institution. The recipient will have been recognized as contributing substantially to physics research and providing inspirational guidance and encouragement of undergraduate students participating in this research. A nominee must be from the faculty of a predominantly undergraduate institution in the United States. The nominee's department may offer a program leading to a master's degree but shall not have a doctoral program in physics. Nominations are active for three years.