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Computing systems have undergone a fundamental transformation from the single-core processor-devices of the turn of the century to today's ubiquitous and networked devices with multicore/many-core processors along with warehouse-scale computing via the cloud. At the same time, semiconductor technology is facing fundamental physical limits and single-processor performance has plateaued. This means that the ability to achieve performance improvements through improved processor technologies alone has ended. In recognition of this obstacle, the recent National Strategic Computing Initiative (NSCI) encourages collaborative efforts to develop, "over the next 15 years, a viable path forward for future high-performance computing (HPC) systems even after the limits of current semiconductor technology are reached (the 'post-Moore's Law era')."

The United States-Israel Collaboration in Computer Science (USICCS) program is a joint program of NSF and the United States - Israel Binational Science Foundation (BSF).  The program supports research projects that develop new knowledge in the areas of theory of computing; algorithm design and analysis; design, verification, and evaluation of software systems; and revolutionary computing models based on emerging scientific ideas.

Computational neuroscience provides a theoretical foundation and a rich set of technical approaches for understanding complex neurobiological systems, building on the theory, methods, and findings of computer science, neuroscience, and numerous other disciplines. Through the CRCNS program, the National Science Foundation (NSF), the National Institutes of Health (NIH), the German Federal Ministry of Education and Research (Bundesministerium für Bildung und Forschung, BMBF), the French National Research Agency (Agence Nationale de la Recherche, ANR), and the United States-Israel Binational Science Foundation (BSF) support collaborative activities that will advance the understanding of nervous system structure and function, mechanisms underlying nervous system disorders, and computational strategies used by the nervous system. 

The Office of Fusion Energy Sciences (FES) and the Office of Advanced Scientific Computing Research (ASCR) of the Office of Science (SC), U.S. Department of Energy (DOE), announce their interest in receiving applications from multi-institutional interdisciplinary teams to establish scientific application partnerships under the SC-wide Scientific Discovery through Advanced Computing (SciDAC) program in the area of integrated simulations for fusion energy sciences. The goal of this announcement is to select applications that can take advantage of today's multi-petascale DOE high-performance computing (DOE HPC) systems to accelerate scientific discovery in strategically important areas of magnetic fusion energy science and address high- priority issues identified in recent community studies. The specific areas of interest under this Funding Opportunity Announcement (FOA) are: 1. Plasma Disruptions in Tokamaks 2. Boundary Physics 3. Plasma-Materials Interactions 4. Whole Device Modeling

Advanced computational infrastructure and the ability to perform large-scale simulations and accumulate massive amounts of data have revolutionized scientific and engineering disciplines.  The goal of the CDS&E program is to identify and capitalize on opportunities for major scientific and engineering breakthroughs through new computational and data analysis approaches.  The intellectual drivers may be in an individual discipline or they may cut across more than one discipline in various Directorates.  The key identifying factor is that the outcome relies on the development, adaptation, and utilization of one or more of the capabilities offered by advancement of both research and infrastructure in computation and data, either through cross-cutting or disciplinary programs. 

CMMT supports theoretical and computational materials research in the topical areas represented in DMR's Topical Materials Research Programs (these are also variously known as Individual Investigator Award (IIA) Programs, or Core Programs, or Disciplinary Programs), which include: Condensed Matter Physics (CMP), Biomaterials (BMAT), Ceramics (CER), Electronic and Photonic Materials (EPM), Metals and Metallic Nanostructures (MMN), Polymers (POL), and Solid State and Materials Chemistry (SSMC). The CMMT program supports fundamental research that advances conceptual understanding of hard and soft materials, and materials-related phenomena; the development of associated analytical, computational, and data-centric techniques; and predictive materials-specific theory, simulation, and modeling for materials research.Research may encompass the advance of new paradigms in materials research, including emerging data-centric approaches utilizing data-analytics or machine learning. Computational efforts span from the level of workstations to advanced and high-performance scientific computing. Emphasis is on approaches that begin at the smallest appropriate length scale, such as electronic, atomic, molecular, nano-, micro-, and mesoscale, required to yield fundamental insight into material properties, processes, and behavior, to predict new materials and states of matter, and to reveal new materials phenomena. Approaches that span multiple scales of length and time may be required to advance fundamental understanding of materials properties and phenomena, particularly for polymeric materials and soft matter.

The Quantum Idea Incubator for Transformational Advances in Quantum Systems (QII - TAQS) program is designed to support interdisciplinary teams that will explore highly innovative, original, and potentially transformative ideas for developing and applying quantum science, quantum computing, and quantum engineering. Proposals with the potential to deliver new concepts, new platforms, and/or new approaches that will accelerate the science, computing, and engineering of quantum technologies are encouraged. Breakthroughs in quantum sensing, quantum communications, quantum simulations, or quantum computing systems are anticipated. This Quantum Idea Incubator solicitation aims to support the process of translating such ideas into reality. This solicitation calls for proposals focused on interdisciplinary research that includes elements from the following thrust areas: (i) fundamental science such as, but not limited to, physics, chemistry, materials science, mathematics, biology, or geoscience, as well as foundational concepts and techniques in quantum information science and engineering; (ii) communication, computation, and modeling; and (iii) devices and engineered systems. Proposals must articulate how the project leverages and/or promotes advances in knowledge in the selected thrust areas.

This program aims to provide all U.S. students the opportunity to participate in computer science (CS) and computational thinking (CT) education in their schools at the preK-12 levels. With this solicitation, the National Science Foundation (NSF) focuses on researcher-practitioner partnerships (RPPs) that foster the research and development needed to bring CS and CT to all schools. Specifically, this solicitation aims to provide high school teachers with the preparation, professional development (PD) and ongoing support that they need to teach rigorous computer science courses; preK-8 teachers with the instructional materials and preparation they need to integrate CS and CT into their teaching; and schools and districts the resources needed to define and evaluate multi-grade pathways in CS and CT.

The Office of Fusion Energy Sciences (FES) and the Office of Advanced Scientific Computing Research (ASCR) of the Office of Science (SC), U.S. Department of Energy (DOE), announce their interest in receiving applications from multi-institutional interdisciplinary teams to establish a scientific application partnership under the Scientific Discovery through Advanced Computing (SciDAC) program in the area of runaway electron physics in magnetically confined plasmas. The goal of this FOA is to select applications that can take advantage of today's multi-petascale DOE high-performance computing (DOE HPC) systems to accelerate scientific discovery in a strategically important area of magnetic fusion energy science and address high-priority issues identified in recent community studies.

The intent of this solicitation is to request proposals from organizations willing to serve as service providers (SPs) within the NSF Innovative High-Performance Computing (HPC) program to provide advanced cyberinfrastructure (CI) capabilities and/or services in production operations to support the full range of computational- and data-intensive research across all of science and engineering (S&E). The current solicitation is intended to complement previous NSF investments in advanced computational infrastructure by provisioning resources, broadly defined in this solicitation to include systems and/or services, in two categories:

This funding opportunity enables engineering and computer science departments to lead the nation by successfully achieving significant sustainable changes necessary to overcome longstanding issues in their undergraduate programs and educate inclusive communities of engineering and computer science students prepared to solve 21st century challenges.

This funding opportunity enables engineering and computer science departments to lead the nation by successfully achieving significant sustainable changes necessary to overcome longstanding issues in their undergraduate programs and educate inclusive communities of engineering and computer science students prepared to solve 21st century challenges.

NSF's Directorate for Engineering (ENG) and the Directorate for Computer and Information Science and Engineering (CISE) have joined to support the Research Experiences for Teachers (RET) in Engineering and Computer Science program. This program supports active long-term collaborative partnerships between K-12 Science, Technology, Engineering, Computer and Information Science, and Mathematics (STEM) in-service and pre-service teachers, full-time community college faculty, and university

The Computer and Information Science and Engineering (CISE) Community Research Infrastructure (CCRI) program drives discovery and learning in the core CISE disciplines of the three participating divisions [(Computing and Communication Foundations (CCF), Computer and Network Systems (CNS), and Information and Intelligent Systems (IIS)] by funding the creation and enhancement of world-class research infrastructure. This research infrastructure will specifically support diverse communities of CISE researchers pursuing focused research agendas in computer and information science and engineering. This support involves developing the accompanying user services and engagement needed to attract, nurture, and grow a robust research community that is actively involved in determining directions for the infrastructure as well as management of the infrastructure. This should lead to infrastructure that can be sustained through community involvement and community leadership, and that will enable advances not possible with existing research infrastructure.

The National Science Foundation (NSF), through its Divisions of Electrical, Communications and Cyber Systems (ECCS), Computing and Communication Foundations (CCF), Molecular and Cellular Biosciences (MCB), and Materials Research (DMR) announces a follow-up solicitation on the Semiconductor Synthetic Biology for Information Storage and Retrieval Program (SemiSynBio-II). Future ultra-low energy storage-based computing systems can be built on principles derived from organic systems that are at the intersection of physics, chemistry, biology, computer science and engineering. Next-generation information storage technologies can be envisioned that are driven by biological principles and use biomaterials in the fabrication of devices and systems that can store data for more than 100 years with storage capacity 1,000 times more than current storage technologies. Such a research effort can have a significant impact on the future of information storage and retrieval technologies. This focused solicitation seeks high-risk/high-return interdisciplinary research on novel concepts and enabling technologies that will address the fundamental scientific issues and technological challenges associated with the underpinnings of synthetic biology integrated with semiconductor technology. This research will foster interactions among various disciplines including biology, physics, chemistry, materials science, computer science and engineering that will enable in heretofore unanticipated breakthroughs.

This program aims to provide all U.S. students with the opportunity to participate in computer science (CS) and computational thinking (CT) education in their schools at the preK-12 levels. With this solicitation, the National Science Foundation (NSF) focuses on both research and researcher-practitioner partnerships (RPPs) that foster the research and development needed to bring CS and CT to all schools. Specifically, this solicitation aims to provide (1) high school teacherswith the preparation, professional development (PD) and ongoing support they need to teach rigorous computer science courses; (2) preK-8 teachers with the instructional materials and preparation they need to integrate CS and CT into their teaching; and (3) schools and districtswith the resources needed to define and evaluate multi-grade pathways in CS and CT.

This program aims to provide all U.S. students the opportunity to participate in computer science (CS) and computational thinking (CT) education in their schools at the preK-12 levels. With this solicitation, the National Science Foundation (NSF) focuses on researcher-practitioner partnerships (RPPs) that foster the research and development needed to bring CS and CT to all schools. Specifically, this solicitation aims to provide high school teachers with the preparation, professional development (PD) and ongoing support that they need to teach rigorous computer science courses; preK-8 teachers with the instructional materials and preparation they need to integrate CS and CT into their teaching; and schools and districts the resources needed to define and evaluate multi-grade pathways in CS and CT.

A key focus of the design of modern computing systems is performance and scalability, particularly in light of the limits of Moore's Law and Dennard scaling. To this end, systems are increasingly being implemented by composing heterogeneous computing components and continually changing memory systems as novel, performant hardware surfaces. Applications fueled by rapid strides in machine learning, data analysis, and extreme-scale simulation are becoming more domain-specific and highly distributed. In this scenario, traditional boundaries between hardware-oriented and software-oriented disciplines increasingly are blurred. Achieving scalability of systems and applications will therefore require coordinated progress in multiple disciplines such as computer architecture, high-performance computing (HPC), programming languages and compilers, security and privacy, systems, theory, and algorithms. Cross-cutting concerns such as performance (including, but not limited to, time, space, and communication resource usage and energy efficiency), correctness and accuracy (including, but not limited to, emerging techniques for program analysis, testing, debugging, probabilistic reasoning and inference, and verification), security and privacy, robustness and reliability, domain-specific design, and heterogeneity must be taken into account from the outset in all aspects of systems and application design and implementation.

Critical infrastructures are the mainstay of our nation's economy, security and health. These infrastructures are interdependent. They are linked to individual preferences and community needs. For example, the electrical power system depends on the delivery of fuels to power generating stations through transportation services, the production of those fuels depends in turn on the use of electrical power, and those fuels are needed by the transportation services. Social networks, interactions, and policies can enable or hinder the successful creation of resilient complex adaptive systems. The goals of the Critical Resilient Interdependent Infrastructure Systems and Processes (CRISP) solicitation are to: (1) foster an interdisciplinary research community of engineers, computer and computational scientists and social and behavioral scientists, that creates new approaches and engineering solutions for the design and operation of infrastructures as processes and services; (2) enhance the understanding and design of interdependent critical infrastructure systems (ICIs) and processes that provide essential goods and services despite disruptions and failures from any cause, natural, technological, or malicious; (3) create the knowledge for innovation in ICIs so that they safely, securely, and effectively expand the range of goods and services they enable; and (4) improve the effectiveness and efficiency with which they deliver existing goods and services.

Critical infrastructures are the mainstay of our nation's economy, security and health. These infrastructures are interdependent. They are linked to individual preferences and community needs. For example, the electrical power system depends on the delivery of fuels to power generating stations through transportation services, the production of those fuels depends in turn on the use of electrical power, and those fuels are needed by the transportation services. Social networks, interactions, and policies can enable or hinder the successful creation of resilient complex adaptive systems. The goals of the Critical Resilient Interdependent Infrastructure Systems and Processes (CRISP) solicitation are to: (1) foster an interdisciplinary research community of engineers, computer and computational scientists and social and behavioral scientists, that creates new approaches and engineering solutions for the design and operation of infrastructures as processes and services; (2) enhance the understanding and design of interdependent critical infrastructure systems (ICIs) and processes that provide essential goods and services despite disruptions and failures from any cause, natural, technological, or malicious; (3) create the knowledge for innovation in ICIs so that they safely, securely, and effectively expand the range of goods and services they enable; and (4) improve the effectiveness and efficiency with which they deliver existing goods and services.

The Scalable Parallelism in the Extreme (SPX) program aims to support research addressing the challenges of increasing performance in this modern era of parallel computing. This will require a collaborative effort among researchers in multiple areas, from services and applications down to micro-architecture. SPX encompasses all five NSCI Strategic Objectives, including supporting foundational research toward architecture and software approaches that drive performance improvements in the post-Moore's Law era; development and deployment of programmable, scalable, and reusable platforms in the national HPC and scientific cyberinfrastructure ecosystem; increased coherence of data analytic computing and modeling and simulation; and capable extreme-scale computing. Coordination with industrial efforts that pursue related goals are encouraged.

Scientific advances such as genomics, quantitative structural biology, imaging techniques, and modeling of complex systems have created opportunities for exciting research careers at the interface between the physical/computational sciences and the biological sciences. Tackling key problems in biology will require scientists trained in areas such as chemistry, physics, applied mathematics, computer science, and engineering. Recognizing the vital role such cross-trained scientists will play in furthering biomedical science, the Burroughs Wellcome Fund has developed the Career Awards at the Scientific Interface. These grants are intended to foster the early career development of researchers who have transitioned or are transitioning from undergraduate and/or graduate work in the physical/mathematical/computational sciences or engineering into postdoctoral work in the biological sciences, and who are dedicated to pursuing a career in academic research. Candidates are expected to draw from their training in a scientific field other than biology to propose innovative approaches to answer important questions in the biological sciences.