The National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) requests applications for the NIAMS Core Centers for Clinical Research (CCCR) (P30) within its mission. The CCCRs will provide avenues to advance the methodological sciences that support clinical research within and across the NIAMS' portfolio of diseases. The overall goals of the CCCR are to advance prevention, diagnosis and treatment of musculoskeletal, rheumatologic, and skin diseases by developing and fostering the implementation of novel methods, metrics, and outcome measures that address critical existing and emerging clinical research needs. 

The NIJ Graduate Research Fellowship (GRF) program in Social and Behavioral Sciences is open to doctoral students in all social and behavioral science disciplines. This program provides awards to accredited academic institutions to support graduate research leading to doctoral degrees in areas that are relevant to ensuring public safety, preventing and controlling crime, and ensuring the fair and impartial administration of criminal justice in the United States. NIJ invests in doctoral education by supporting academic institutions that sponsor students who demonstrate the potential to successfully complete doctoral degree programs in disciplines relevant to the mission of NIJ and who are in the final stages of graduate study. Applicants sponsoring doctoral students are eligible to apply only (1) if the doctoral student'‚ƒƒ™s degree program is a Social and Behavioral Science discipline and (2) if the student's proposed dissertation research has direct implications for criminal justice policy and practice in the United States.

NASA and the Sloan Foundation have agreed through a Space Act Agreement to work in parallel for a common purpose: to sponsor studies designed to provide insight into the microbiome of the built environment of the ISS that will advance our knowledge and understanding of human-built habitats on Earth, to enhance ISS utilization, and to inform the development of future space exploration vehicles that are occupied by humans. NASA is soliciting, through this Appendix, research applications for Postdoctoral Fellowships from early career scientists to design experiments that utilize a NASA collection of ISS microbial isolates collected over a decade or more to help understand better how microbial communities colonize, adapt, and evolve on the ISS. All proposals must propose experiments that utilize these microbial isolates collected from the ISS that have been archived at the Johnson Space Center.

Morton Cure Paralysis Fund (MCPF) is committed to developing effective therapies (cures) for paralysis associated with spinal cord injury and other disorders of the central nervous system (CNS).  MCPF funds activities that hold promise of identifying therapies (cures) for paralysis in humans. MCPF has particular focus of placing projects in the research pipeline that is, enabling scientists to develop the proof concept data necessary to apply for larger NIH grants. MCPF has particular focus of placing projects in the research pipeline that is, enabling scientists to develop the proof concept data necessary to apply for larger NIH grants. The development of effective therapies for chronic injury is a high priority for the organization. Basic research will be supported if it has clear potential to accelerate progress at the applied end of the continuum and/or if it reflects innovative research or a 'change of direction.

The Common Fund Program - Accelerating Translation of Glycoscience: Integration and Accessibility - aims to develop accessible and affordable new tools and technologies for studying carbohydrates that will allow biomedical researchers to significantly advance our understanding of the roles of these complex molecules in health and disease. This program will enable investigators who might not otherwise conduct research in the glycosciences, to undertake the study of carbohydrate structure and function. In support of these aims, this FOA seeks applications for a community-driven project to develop computational and informatics tools for the manipulation, analysis, interpretation, and integration of glycoscience data. The product of this research will be accessible resources for analysis of carbohydrate and glycoconjugate structural, analytical, and interaction data, and integration of that information within the context of comparable gene, protein, and lipid data and databases.

The Howard Hughes Medical Institute (HHMI) today announced a new program to recruit and retain early-career scientists who are from gender, racial, ethnic, and other groups underrepresented in the life sciences, including those from disadvantaged backgrounds. Through an open competition, HHMI plans to select scientists early in their training to become Hanna H. Gray Fellows. Each fellow will receive funding for up to eight years, with mentoring and active involvement within the HHMI community. In this two-phase program, fellows will be supported from early postdoctoral training through several years of a tenure-track faculty position. In the first competition cycle, HHMI will select up to 15 fellows and invest a total of up to $25 million for their support over eight years.

Most survey-based prevalence estimates of type 1 diabetes among adults have been based on self-reported information about a young age at diagnosis (e.g.,30 years and 40 years) and insulin use within a year of diagnosis. However, this estimation approach misses type 1 diabetes in adults with older age of onset and may misclassify some cases of type 2 diabetes as type 1 if insulin use begins soon after diagnosis. The major goal of this project is to evaluate the validity of survey questions (or algorithms based on them) to distinguish between adults (aged 18 years of age) with type 1 and type 2 diabetes in a representative sample of adult diabetic patients in a diabetes patient registry or database. Using a gold standard, validity will be assessed by examining the sensitivity, specificity, and positive predictive value of algorithms to identify type of diabetes across demographic strata such as age, sex, and race. A secondary goal is to validate definitions of type of diabetes using electronic health records.

RWJF is now looking for researchers to study the impact the program has had on the changing face of nursing. Up to four grants of $3,000 each will be awarded to individual researchers for the development of a manuscript in one of the following categories: supports and barriers for accelerated nursing students; characteristics of male nursing students; increasing diversity and cultural climate of nursing schools; student debt and accelerated nursing education: policy implications; and effective mentoring/necessary components.

The Centers of Excellence in Genomic Science (CEGS) program establishes academic Centers for advanced genome research.  Each CEGS grant supports a multi-investigator, interdisciplinary team to develop innovative genomic approaches to address a particular biomedical problem.  A CEGS project will address a critical issue in genomic science or genomic medicine, proposing a solution that would be a very substantial advance.  Thus, the research conducted at these Centers will entail substantial risk, balanced by outstanding scientific and management plans and very high potential payoff.  A CEGS will focus on the development of novel technological or computational methods for the production or analysis of comprehensive data sets, or on a particular genome-scale biomedical problem, or on other ways to develop and use genomic approaches for understanding biological systems and/or significantly furthering the application of genomic knowledge, data and methods towards clinical applications.  Exploiting its outstanding scientific plan and team, each CEGS will nurture genomic science at its institution by facilitating the interaction of investigators from different disciplines, and by providing training to new and experienced investigators, it will expand the pool of highly-qualified professional genomics scientists and engineers.

The Improving Teacher Quality State Grants Program is funded under the No Child Left Behind (NCLB) Act of 2001 (Title II, Part A of Public Law 107-110). The purpose of the program is to increase the academic achievement of all students by helping schools and school districts improve teacher, instructional paraprofessional and principal quality. Ohio public and private colleges and universities are invited annually to submit proposals to support partnerships of institutions of higher education and high-need school districts to provide high quality professional development for elementary, middle and high school teachers of mathematics and science.

An objective of the Critical Infrastructure Resilience Institute (CIRI) is to bring together capabilities of colleges, universities, federal laboratories, industry, and nonprofit organizations to assess and improve resilience in the ten critical infrastructures for which the Department of Homeland Security is the designated sector-specific agency: * Chemical * Commercial Facilities * Communications * Critical Manufacturing * Dams * Emergency Services * Government Facilities * Information Technology * Nuclear Reactors, Materials, and Waste * Transportation Systems CIRI activities are organized around four themes: 1. Understanding resilient critical infrastructure systems. 2. Application of critical infrastructure in the real world. 3. The business case for infrastructure resiliency. 4. The future of resiliency. With those objectives in mind, CIRI is seeking proposals for projects that will improve the nation's ability to * Understand vulnerabilities and risks * Quantitatively assess risks and resilience measures * Mitigate risks and improve resilience * Establish the business case for resiliency * Deploy resiliency measures

Computational neuroscience provides a theoretical foundation and a rich set of technical approaches for understanding complex neurobiological systems, building on the theory, methods, and findings of computer science, neuroscience, and numerous other disciplines. Through the CRCNS program, the National Science Foundation (NSF), the National Institutes of Health (NIH), the German Federal Ministry of Education and Research (Bundesministerium für Bildung und Forschung, BMBF), the French National Research Agency (Agence Nationale de la Recherche, ANR), and the United States-Israel Binational Science Foundation (BSF) support collaborative activities that will advance the understanding of nervous system structure and function, mechanisms underlying nervous system disorders, and computational strategies used by the nervous system. 

The NSF/Intel Partnership on Computer Assisted Programming for Heterogeneous Architectures (CAPA) aims to address the problem of effective software development for diverse hardware architectures through groundbreaking university research that will lead to a significant, measurable leap in software development productivity by partially or fully automating software development tasks that are currently performed by humans. The main research objectives for CAPA include programmer effectiveness, performance portability, and performance predictability. In order to address these objectives, CAPA seeks research proposals that explore (1) programming abstractions and/or methodologies that separate performance-related aspects of program design from how they are implemented; (2) program synthesis and machine learning approaches for automatic software construction that are demonstrably correct; (3) advanced hardware-based cost models and abstractions to support multi-target code generation and performance predictability for specified heterogeneous hardware architectures; and (4) integration of research results into principled software development practices.

Algorithms in the Field encourages closer collaboration between two groups of researchers: (i) theoretical computer science researchers, who focus on the design and analysis of provably efficient and provably accurate algorithms for various computational models; and (ii) other computing and information researchers including a combination of systems and domain experts (very broadly construed - including but not limited to researchers in computer architecture, programming languages and systems, computer networks, cyber-physical systems, cyber-human systems, machine learning, artificial intelligence and its applications, database and data analytics, etc.) who focus on the particular design constraints of applications and/or computing devices. Each proposal must have at least one co-PI interested in theoretical computer science and one interested in any of the other areas typically supported by CISE. Proposals are expected to address the dissemination of both the algorithmic contributions and the resulting applications, tools, languages, compilers, libraries, architectures, systems, data, etc.

Algorithms in the Field encourages closer collaboration between two groups of researchers: (i) theoretical computer science researchers, who focus on the design and analysis of provably efficient and provably accurate algorithms for various computational models; and (ii) other computing and information researchers including a combination of systems and domain experts (very broadly construed - including but not limited to researchers in computer architecture, programming languages and systems, computer networks, cyber-physical systems, cyber-human systems, machine learning, artificial intelligence and its applications, database and data analytics, etc.) who focus on the particular design constraints of applications and/or computing devices. Each proposal must have at least one co-PI interested in theoretical computer science and one interested in any of the other areas typically supported by CISE. Proposals are expected to address the dissemination of both the algorithmic contributions and the resulting applications, tools, languages, compilers, libraries, architectures, systems, data, etc.

The SNM-IS solicitation seeks proposals that investigate novel scalable nanomanufacturing and integration methods for nano-enabled integrated systems with a clear commercial relevance. Proposals should consider addressing key aspects of the nanomanufacturing value chain comprised of nano-scale building-blocks → complex nanomaterials and nanostructures → functional components and devices → integrated sub-systems and systems

The Scalable Parallelism in the Extreme (SPX) program aims to support research addressing the challenges of increasing performance in this modern era of parallel computing. This will require a collaborative effort among researchers in multiple areas, from services and applications down to micro-architecture. SPX encompasses all five NSCI Strategic Objectives, including supporting foundational research toward architecture and software approaches that drive performance improvements in the post-Moore's Law era; development and deployment of programmable, scalable, and reusable platforms in the national HPC and scientific cyberinfrastructure ecosystem; increased coherence of data analytic computing and modeling and simulation; and capable extreme-scale computing. Coordination with industrial efforts that pursue related goals are encouraged.

Algorithms in the Field encourages closer collaboration between two groups of researchers: (i) theoretical computer science researchers, who focus on the design and analysis of provably efficient and provably accurate algorithms for various computational models; and (ii) other computing and information researchers including a combination of systems and domain experts (very broadly construed - including but not limited to researchers in computer architecture, programming languages and systems, computer networks, cyber-physical systems, cyber-human systems, machine learning, artificial intelligence and its applications, database and data analytics, etc.) who focus on the particular design constraints of applications and/or computing devices. Each proposal must have at least one co-PI interested in theoretical computer science and one interested in any of the other areas typically supported by CISE. Proposals are expected to address the dissemination of both the algorithmic contributions and the resulting applications, tools, languages, compilers, libraries, architectures, systems, data, etc.

Algorithms in the Field encourages closer collaboration between two groups of researchers: (i) theoretical computer science researchers, who focus on the design and analysis of provably efficient and provably accurate algorithms for various computational models; and (ii) other computing and information researchers including a combination of systems and domain experts (very broadly construed - including but not limited to researchers in computer architecture, programming languages and systems, computer networks, cyber-physical systems, cyber-human systems, machine learning, artificial intelligence and its applications, database and data analytics, etc.) who focus on the particular design constraints of applications and/or computing devices. Each proposal must have at least one co-PI interested in theoretical computer science and one interested in any of the other areas typically supported by CISE. Proposals are expected to address the dissemination of both the algorithmic contributions and the resulting applications, tools, languages, compilers, libraries, architectures, systems, data, etc.

The goal of the Smart and Connected Health (SCH) Program is to accelerate the development and use of innovative approaches that would support the much needed transformation of healthcare from reactive and hospital-centered to preventive, proactive, evidence-based, person-centered and focused on well-being rather than disease. Approaches that partner technology-based solutions with biobehavioral health research are supported by multiple agencies of the federal government including the National Science Foundation (NSF) and the National Institutes of Health (NIH). The purpose of this program is to develop next generation health care solutions and encourage existing and new research communities to focus on breakthrough ideas in a variety of areas of value to health, such as sensor technology, networking, information and machine learning technology, decision support systems, modeling of behavioral and cognitive processes, as well as system and process modeling. Effective solutions must satisfy a multitude of constraints arising from clinical/medical needs, social interactions, cognitive limitations, barriers to behavioral change, heterogeneity of data, semantic mismatch and limitations of current cyberphysical systems. Such solutions demand multidisciplinary teams ready to address technical, behavioral and clinical issues ranging from fundamental science to clinical practice.

The goal of the Smart and Connected Health (SCH) Program is to accelerate the development and use of innovative approaches that would support the much needed transformation of healthcare from reactive and hospital-centered to preventive, proactive, evidence-based, person-centered and focused on well-being rather than disease. Approaches that partner technology-based solutions with biobehavioral health research are supported by multiple agencies of the federal government including the National Science Foundation (NSF) and the National Institutes of Health (NIH). The purpose of this program is to develop next generation health care solutions and encourage existing and new research communities to focus on breakthrough ideas in a variety of areas of value to health, such as sensor technology, networking, information and machine learning technology, decision support systems, modeling of behavioral and cognitive processes, as well as system and process modeling. Effective solutions must satisfy a multitude of constraints arising from clinical/medical needs, social interactions, cognitive limitations, barriers to behavioral change, heterogeneity of data, semantic mismatch and limitations of current cyberphysical systems. Such solutions demand multidisciplinary teams ready to address technical, behavioral and clinical issues ranging from fundamental science to clinical practice.

The HFC program seeks proposals for research to develop and test hybrid geopolitical forecasting systems. These systems will integrate human and machine forecasting components to create maximally accurate, flexible, and scalable forecasting capabilities. Human-generated forecasts may be subject to cognitive biases and/or scalability limits. Machine-generated (i.e., statistical, computational) forecasting approaches may be more scalable and data-driven, but are often ill-suited to render forecasts for idiosyncratic or newly emerging geopolitical issues. Hybrid approaches hold promise for combining the strengths of these two approaches while mitigating their individual weaknesses. Performers will develop systems that will integrate human and machine forecasting contributions in novel ways. These systems will compete in a multi-year competition to identify approaches that may enable the Intelligence Community (IC) to radically improve the accuracy and timeliness of geopolitical forecasts.

The HFC program seeks proposals for research to develop and test hybrid geopolitical forecasting systems. These systems will integrate human and machine forecasting components to create maximally accurate, flexible, and scalable forecasting capabilities. Human-generated forecasts may be subject to cognitive biases and/or scalability limits. Machine-generated (i.e., statistical, computational) forecasting approaches may be more scalable and data-driven, but are often ill-suited to render forecasts for idiosyncratic or newly emerging geopolitical issues. Hybrid approaches hold promise for combining the strengths of these two approaches while mitigating their individual weaknesses. Performers will develop systems that will integrate human and machine forecasting contributions in novel ways. These systems will compete in a multi-year competition to identify approaches that may enable the Intelligence Community (IC) to radically improve the accuracy and timeliness of geopolitical forecasts.

As part of this mission, CCCD has issued a Request for Proposals for a new pilot grant initiative that aims to support the expanding definition of craft-based research and promote collaboration between the fields of craft, science, technology, engineering, and mathematics.   Through the Materials-Based Research Grant program, grants of up to $15,000 over eighteen months will be awarded to interdisciplinary teams of researchers to encourage mutually beneficial innovation in craft and STEM fields, with a focus on materials and process-based research. The teams should include one maker and one professional working in a STEM-based field (e.g., material science, manufacturing, environmental studies, medicine, structural engineering, etc.). This can include academics, researchers, scientists, full-time makers, or other skilled specialists.

As part of this mission, CCCD has issued a Request for Proposals for a new pilot grant initiative that aims to support the expanding definition of craft-based research and promote collaboration between the fields of craft, science, technology, engineering, and mathematics.   Through the Materials-Based Research Grant program, grants of up to $15,000 over eighteen months will be awarded to interdisciplinary teams of researchers to encourage mutually beneficial innovation in craft and STEM fields, with a focus on materials and process-based research. The teams should include one maker and one professional working in a STEM-based field (e.g., material science, manufacturing, environmental studies, medicine, structural engineering, etc.). This can include academics, researchers, scientists, full-time makers, or other skilled specialists.