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MiamiOH OARS

DeGregorio Family Foundation for Gastric and Esophageal Cancer Invites Research Proposa... - 0 views

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    The DeGregorio Family Foundation for Gastric and Esophageal Cancer seeks to promote and facilitate collaborative research on the pathogenesis, early diagnosis, and treatment of upper gastrointestinal malignancies.

    To that end, the foundation has issued a Request for Proposals for its ninth annual funding opportunity for gastroesophageal malignancies. Through the RFP, grants of up to $250,000 will be awarded in support of innovative, high-quality translational and bench research that improves the understanding of the biology of these diseases, identification of potential novel therapeutic targets, and/or the development and evaluation of novel biomarkers for early diagnosis and treatment. Pre-clinical research, basic mechanistic studies, genomic/epigenomic studies, and epidemiologic studies are eligible for support.
MiamiOH OARS

Skin Cancer Foundation Issues Request for Proposals for Research Projects | RFPs | PND - 0 views

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    Since its founding in 1979, the Skin Cancer Foundation has set the standard for educating the public and the medical community about skin cancer. The foundation is committed to reducing the incidence and mortality of the world's most common cancer, which is now occurring at epidemic levels.

    As part of this mission, the foundation is accepting proposals for its 2019 Research Grants Awards program.

    Two grants of $50,000 and one grant of $25,000 will be awarded to support one-year pilot research projects related to the disease. Researchers are invited to submit applications for projects to be conducted within the dermatology departments of medical institutions in the United States and Canada.

    The program is open to dermatology residents, fellows, and junior investigators.
MiamiOH OARS

American Society of Breast Surgeons Foundation Accepting Applications for Education, Re... - 0 views

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    The American Society of Breast Surgeons Foundation awards grants related to patient breast care and medical education. The foundation is a charitable organization dedicated to improving the standard of care for breast disease patients by providing support for medical and patient education, advancing breast disease research and diagnosis and treatment technologies, and offering programs and services to medical professionals and their patients.

MiamiOH OARS

Fc-Dependent Mechanisms of Antibody-Mediated Killing (R21 Clinical Trial Not Allowed) - 0 views

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    This Funding Opportunity Announcement (FOA) invites R21 applications for studies that address knowledge gaps in mechanisms of Fc-dependent, antibody-mediated killing of infected cells or aberrant cells, or antibody-mediated therapeutic ablation of cells implicated in immune pathologies, including autoimmune and allergic diseases. More specifically, the purpose of this FOA is to promote innovative and exploratory research to elucidate mechanisms of antibody-dependent cellular cytotoxicity (ADCC) and antibody-dependent cell-mediated phagocytosis (ADCP), and to promote development of tools, technologies, and animal models to facilitate identification and evaluation of cytotoxic killing mechanisms mediated by human antibodies in vivo.
MiamiOH OARS

Mechanisms of Disparities in Etiology and Outcomes of Lung Cancer in the U.S.: The Role... - 0 views

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    This initiative will support exploratory and developmental multidisciplinary research to understand the underlying causal factors and mechanisms that result in lung cancer disparities in U.S. health disparity populations.
MiamiOH OARS

Mechanisms of Disparities in Etiology and Outcomes of Lung Cancer in the U.S.: The Role... - 0 views

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    This initiative will support multidisciplinary research to understand the underlying causal factors and mechanisms that result in lung cancer disparities in U.S. health disparity populations.
MiamiOH OARS

Clinical Trial Readiness for Rare Diseases, Disorders, and Syndromes (R03 Clinical Tria... - 0 views

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    This Funding Opportunity Announcement (FOA) invites researchers to submit applications for support of clinical projects that address critical needs for clinical trial readiness in rare diseases. The initiative seeks applications that are intended to facilitate rare disease research by enabling efficient and effective movement of candidate therapeutics or diagnostics towards clinical trials, and to increase their likelihood of success through development and testing of rigorous biomarkers and clinical outcome assessment measures, or by defining the presentation and course of a rare disease to enable the design of upcoming clinical trials.
MiamiOH OARS

Integrating Biospecimen Science Approaches into Clinical Assay Development (U01 Clinica... - 0 views

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    This Funding Opportunity Announcement (FOA) will support extramural research to investigate and mitigate challenges facing clinical assay development and subsequent analytical validation due to preanalytical variability in tumor tissue biopsies and blood biospecimens utilized as liquid biopsies. Extramural research funded under this FOA may include investigations of preanalytical variability relevant to diagnostic associated with the procurement and study of small biopsies (core biopsies, small excision samples), pleural aspirates, and blood utilized for liquid biopsies. Investigator-designed experiments will explore how different biospecimen preanalytical conditions affect emerging and clinically relevant biomarkers quantified by a variety of testing platforms. The results from this research program will improve the understanding of how analytical quantification of clinically relevant biomarkers is affected by variation in biospecimen collection, processing, and storage procedures. The overall goal is to expedite biomarker clinical assay development through evidence-based standardization of biopsy handling practices.
MiamiOH OARS

Children's Tumor Foundation Issues RFP for NF1 Gene Editing Research | RFPs | PND - 0 views

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    The Children's Tumor Foundation has issued a Request for Proposals for research related to gene-based therapeutic approaches for the treatment of neurofibromatosis type 1 (NF1).

    The initiative will support proof of principle in vitro studies focused on the feasibility of genome editing techniques (including but not limited to those based on CRISPR-Cas9) to correct pathogenic mutations in NF1 gene. Funding for each study will be $240,000 total (inclusive of 10 percent indirect costs) over two years.
MiamiOH OARS

Pancreatic Cancer Action Network Seeks Applications for Translational Research Program ... - 0 views

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    The Pancreatic Cancer Action Network is accepting applications for its 2019 Translational Research grant program. Through the program, grants of up to $500,000 over two years will be awarded for high-priority pancreatic cancer research that is poised for important translational next steps. For the purposes of this grant, translational research is defined according to the framework conceived by the Translational Research Working Group created under the auspices of the U.S. National Cancer Advisory Board. Specifically, the program supports research that follows fundamental discovery all the way through Phase I/II clinical trials.
MiamiOH OARS

View Opportunity | GRANTS.GOV - 0 views

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    The Center to Reduce Cancer Health Disparities (CRCHD) of the National Cancer Institute (NCI), in partnership with the NCI Office of Cancer Centers (OCC), announces this opportunity to compete for administrative supplements to Cancer Center Support Grants (CCSGs; P30s) for NCI-designated Cancer Centers (CCs) to each recruit a Community Health Educator (CHE). The purpose of this administrative supplement funding opportunity is to support a strengthening of community outreach capacity by working through the National Outreach Network (NON). It is expected that NON CHEs, located at NCI-designated CCs, will enhance the development and dissemination of culturally appropriate, evidence-based cancer information to members of underserved communities including rural and racial/ethnic populations (e.g., African American/Black, American Indian/Alaska Native, Asian, Hispanic/Latino, Native Hawaiian/Other Pacific Islander) in a way that is tailored to their specific needs.
MiamiOH OARS

The NCI Predoctoral to Postdoctoral Fellow Transition Award (F99/K00) - 0 views

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    The purpose of the NCI Predoctoral to Postdoctoral Fellow Transition Award (F99/K00) is to encourage and retain outstanding graduate students recognized by their institutions for their high potential and strong interest in pursuing careers as independent cancer researchers. The award will facilitate the transition of talented graduate students into successful cancer research postdoctoral appointments, and provide opportunities for career development activities relevant to their long-term career goals of becoming independent cancer researchers.
MiamiOH OARS

Fellowships | UICC - 0 views

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    Through its fellowship programme, UICC aims to support health workers and cancer professionals focussing on cancer control, including cancer prevention, early detection, epidemiology, implementation and translational research, cancer treatment (surgery, radio- and chemotherapy), multidisciplinary patient care, rehabilitation, survivorship and palliative care. In 2018 there are 3 programmes available, the UICC Technical Fellowships (UICC-TF)  which provides the learning of new knowledge and skills in cancer control through a one month visit to an institution abroad, the YY study grants allow established cancer professionals to visit an institution abroad for 3 months to foster collaboration and knowledge sharing, and Bourses pour l'Afrique Francophone for cancer professionals in Francophone Africa.
MiamiOH OARS

The NCI Predoctoral to Postdoctoral Fellow Transition Award (F99/K00) - 0 views

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    The purpose of the NCI Predoctoral to Postdoctoral Fellow Transition Award (F99/K00) is to encourage and retain outstanding graduate students recognized by their institutions for their high potential and strong interest in pursuing careers as independent cancer researchers. The award will facilitate the transition of talented graduate students into successful cancer research postdoctoral appointments, and provide opportunities for career development activities relevant to their long-term career goals of becoming independent cancer researchers.
MiamiOH OARS

Cancer Prevention Clinical Trials Network (CP-CTNet): Data Management, Auditing, and Co... - 0 views

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    This Funding Opportunity Announcement (FOA) is a part of the National Cancer Institute (NCI) initiative intended to support Cancer Prevention Clinical Trials Network (CP-CTNet). The goals for the CP-CTNet include: Design and conduct early phase clinical trials to assess the safety, tolerability, and cancer preventive potential of agents and interventions of varying classes, many of which target molecules or processes known to be important during carcinogenesis. These trials include phase 0 (microdosing), phase I (dose-finding), and phase II (preliminary efficacy) clinical trials; Characterization of the effects of these agents and interventions on their molecular targets, as well as on other biological events associated with cancer development (such as cell proliferation, apoptosis, growth factor expression, oncogene expression, immune response) and correlation of these effects with clinical endpoints. Development of further scientific insights into the mechanisms of cancer prevention by the agents examined, including the development of novel potential markers as determinants of response.
MiamiOH OARS

Cancer Prevention Clinical Trials Network (CP-CTNet): Data Management, Auditing, and Co... - 0 views

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    Through this funding opportunity announcement (FOA), the National Cancer Institute (NCI) proposes and will support the Cancer Prevention Clinical Trials Network (CP-CTNet), for which the goals are as follows:

    Design and conduct of early phase clinical trials to assess the safety, tolerability, and cancer preventive potential of agents and interventions of varying classes, many of which target molecules or processes known to be important during carcinogenesis. These trials include phase 0 (micro-dosing), phase I (dose-finding), and phase II (preliminary efficacy) clinical trials.

    Characterization of the effects of these agents and interventions on their molecular targets, as well as on other biological events associated with cancer development (such as cell proliferation, apoptosis, growth factor expression, oncogene expression, immune response) and correlation of these effects with clinical endpoints.

    Development of further scientific insights into the mechanisms of cancer prevention by the agents examined, including the development of novel potential markers as determinants of response.
MiamiOH OARS

Communication and Decision Making for Individuals with Inherited Cancer Syndromes (U01 ... - 0 views

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    The purpose of this FOA is to develop, test, and evaluate interventions and implementation approaches, or adapt existing approaches, to improve patient/provider/family risk communication and decision making for individuals and families with an inherited susceptibility to cancer.
MiamiOH OARS

Fusion Oncoproteins in Childhood Cancers (FusOnC2) Consortium (U54 Clinical Trial Not A... - 0 views

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    The purpose of this FOA is to promote research on the following area designated as a scientific priority by the Blue Ribbon Panel (BRP): Recommendation E. Intensify research on the major drivers of childhood cancers: Improve our understanding of fusion oncoproteins in pediatric cancer and use new preclinical models to develop inhibitors that target them. The goal of this FOA is to establish a consortium of collaborating research teams to advance our understanding of the biology and mechanisms of action of fusion oncoproteins in pediatric cancers, and to apply this knowledge towards developing targeted therapeutic approaches.
MiamiOH OARS

Quantitative Imaging Tools and Methods for Cancer Response Assessment (R01 Clinical Tri... - 0 views

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    This purpose of this Funding Opportunity Announcement (FOA) is to provide a mechanism of support to research organizations interested in clinically translating already optimized quantitative imaging software tools capable of measuring or predicting the response of cancer to clinical therapies, or in translating imaging software tools for planning and validating radiation therapy treatment strategies in clinical trials. The quantitative software tools must have been developed and optimized during a performance period in the Quantitative Imaging Network (QIN) or under other separate funding. The proposed research effort should be an extension of the research that successfully completed the tasks of developing and optimizing the chosen software tools or data collection methods intended to facilitate clinical decision making during clinical trials. This FOA is intended to support the efforts of validating those software tools in prospective multisite clinical trials to test software tool performance and to demonstrate that the software tool can be integrated into clinical workflow with a minimum of disruption.
MiamiOH OARS

Fusion Oncoproteins in Childhood Cancers (FusOnC2) Consortium (U54 Clinical Trial Not A... - 0 views

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    The FOA will focus on fusion oncoproteins found in tumors that have high risk of treatment failure and for which there has been little progress in identifying targeted agents. Responsive applications can focus on any fusion oncoprotein in pediatric solid tumors or on NUP98 fusion proteins that occur in young children with acute myelogenous leukemia (AML). However, greater preference will be given to applications focused on PAX-FOXO (alveolar rhabdomyosarcoma), C11orf95RELA (ependymoma), or NUP98 fusion proteins.
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