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MiamiOH OARS

Pancreatic Cancer Network Accepting Applications for Translational Research Program | R... - 0 views

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    This year, PCAN has partnered with the Celgene Corporation to accelerate the development of novel therapies by establishing strong relationships between academia and industry through research grants. Funded projects will benefit from industry input and insight, leading to an accelerated translation to a therapeutic product. Projects should aim to identify novel targets and approaches to the treatment of pancreatic cancer or understand and circumvent treatment resistance. Of particular interest are projects that fall into at least one of these three areas of research: a) immune context and tumor micro-environment interactions; (b) regulators of pathogenesis, progression, and metabolism, with particular interest in epigenetic mechanisms; and (c) transcriptional networks essential for viability and maintenance of malignant phenotype.
MiamiOH OARS

The CDC Cancer Genomics Program: Translating Research into Public Health Practice - 0 views

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    The CDC, Division of Cancer Prevention and Control (DCPC) announces the availability of Fiscal Year 2019 funds to implement DP19-1905, The CDC Cancer Genomics Program: Translating Research into Public Health Practice. This program addresses the utilization of cancer genetic services as a strategy for cancer prevention and control. The primary outcomes of this NOFO are to increase screening of cancer family history and to increase the use of genetic counseling and testing for Hereditary Breast and Ovarian Cancer (HBOC) and Lynch Syndrome (LS) among individuals meeting recommendations for referral. This funding opportunity supports the implementation and evaluation of public health activities within four core strategies to build the evidence base and disseminate best practices. These priorities will be accomplished by funding up to 5 awardees to develop, implement, and evaluate state-level programs in cancer genomics. Funding will support applicants that demonstrate: Appropriate experience with surveillance systems, partners and similar work in cancer genomics Appropriate organizational capacity to perform, implement, and evaluate activities and strategies An approach that is consistent with the strategies and outcomes described in the NOFO An ability to collect data towards key performance measures and outcomes Innovative methods and approaches to program and strategy implementation
MiamiOH OARS

Lymphatics in Health and Disease in the Digestive System (R01 Clinical Trial Not Allowed) - 0 views

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    The purpose of this FOA is to invite applications that investigate aspects of lymphatic vessel physiology, development and pathophysiology related to health and diseases of the digestive system. Studies to understand the factors that control local lymphatic vessel functional anatomy and physiology and development during health or disease in this system and its organs, and the mechanisms by which alterations of lymphatic vessel function affect organ function, are of interest. However, studies with the major focus on immune mechanisms, role of lymphatics in cancer metastasis and study of lymphatic vessels in organs other than those from the digestive system will not be considered responsive.
MiamiOH OARS

DeGregorio Family Foundation for Gastric and Esophageal Cancer Invites Research Proposa... - 0 views

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    The DeGregorio Family Foundation for Gastric and Esophageal Cancer seeks to promote and facilitate collaborative research on the pathogenesis, early diagnosis, and treatment of upper gastrointestinal malignancies. To that end, the foundation has issued a Request for Proposals for its ninth annual funding opportunity for gastroesophageal malignancies. Through the RFP, grants of up to $250,000 will be awarded in support of innovative, high-quality translational and bench research that improves the understanding of the biology of these diseases, identification of potential novel therapeutic targets, and/or the development and evaluation of novel biomarkers for early diagnosis and treatment. Pre-clinical research, basic mechanistic studies, genomic/epigenomic studies, and epidemiologic studies are eligible for support.
MiamiOH OARS

Skin Cancer Foundation Issues Request for Proposals for Research Projects | RFPs | PND - 0 views

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    Since its founding in 1979, the Skin Cancer Foundation has set the standard for educating the public and the medical community about skin cancer. The foundation is committed to reducing the incidence and mortality of the world's most common cancer, which is now occurring at epidemic levels. As part of this mission, the foundation is accepting proposals for its 2019 Research Grants Awards program. Two grants of $50,000 and one grant of $25,000 will be awarded to support one-year pilot research projects related to the disease. Researchers are invited to submit applications for projects to be conducted within the dermatology departments of medical institutions in the United States and Canada. The program is open to dermatology residents, fellows, and junior investigators.
MiamiOH OARS

American Society of Breast Surgeons Foundation Accepting Applications for Education, Re... - 0 views

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    The American Society of Breast Surgeons Foundation awards grants related to patient breast care and medical education. The foundation is a charitable organization dedicated to improving the standard of care for breast disease patients by providing support for medical and patient education, advancing breast disease research and diagnosis and treatment technologies, and offering programs and services to medical professionals and their patients.
MiamiOH OARS

Mechanisms of Disparities in Etiology and Outcomes of Lung Cancer in the U.S.: The Role... - 0 views

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    This initiative will support exploratory and developmental multidisciplinary research to understand the underlying causal factors and mechanisms that result in lung cancer disparities in U.S. health disparity populations.
MiamiOH OARS

Mechanisms of Disparities in Etiology and Outcomes of Lung Cancer in the U.S.: The Role... - 0 views

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    This initiative will support multidisciplinary research to understand the underlying causal factors and mechanisms that result in lung cancer disparities in U.S. health disparity populations.
MiamiOH OARS

Clinical Trial Readiness for Rare Diseases, Disorders, and Syndromes (R03 Clinical Tria... - 0 views

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    This Funding Opportunity Announcement (FOA) invites researchers to submit applications for support of clinical projects that address critical needs for clinical trial readiness in rare diseases. The initiative seeks applications that are intended to facilitate rare disease research by enabling efficient and effective movement of candidate therapeutics or diagnostics towards clinical trials, and to increase their likelihood of success through development and testing of rigorous biomarkers and clinical outcome assessment measures, or by defining the presentation and course of a rare disease to enable the design of upcoming clinical trials.
MiamiOH OARS

The NCI Predoctoral to Postdoctoral Fellow Transition Award (F99/K00) - 0 views

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    The purpose of the NCI Predoctoral to Postdoctoral Fellow Transition Award (F99/K00) is to encourage and retain outstanding graduate students recognized by their institutions for their high potential and strong interest in pursuing careers as independent cancer researchers. The award will facilitate the transition of talented graduate students into successful cancer research postdoctoral appointments, and provide opportunities for career development activities relevant to their long-term career goals of becoming independent cancer researchers.
MiamiOH OARS

Communication and Decision Making for Individuals with Inherited Cancer Syndromes (U01 ... - 0 views

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    This Funding Opportunity Announcement (FOA) is associated with the Beau Biden Cancer MoonshotSM Initiative (https://www.cancer.gov/research/key-initiatives/moonshot-cancer-initiative) that is intended to accelerate cancer research. The purpose of this FOA is to develop, test, and evaluate interventions and implementation approaches, or adapt existing approaches, to improve patient/provider/family risk communication and decision making for individuals and families with an inherited susceptibility to cancer. Specifically, this FOA targets the following area designated as a scientific priority by the Blue Ribbon Panel (https://www.cancer.gov/research/key-initiatives/moonshot-cancer-initiative/blue-ribbon-panel/prevention-screening-working-group-report.pdf) Recommendation G (https://www.cancer.gov/research/key-initiatives/moonshot-cancer-initiative/blue-ribbon-panel#ui-id-3 ): "Sponsor initiatives to improve the current state of early detection, genetic testing, genetic counseling, and knowledge landscape of the mechanisms and biomarkers associated with cancer development and conduct implementation science research to accelerate development, testing, and broader adoption of proven strategies to significantly reduce cancer risk and address cancer health disparities in these areas." This Funding Opportunity Announcement invites U01 applications for projects that develop, test, and evaluate interventions and implementation approaches, or adapt existing approaches, to improve patient/provider/family risk communication and decision making for individuals and families with an inherited susceptibility to cancer so that they can make informed clinical risk management decisions.
MiamiOH OARS

Prevention of HPV-related Cancers in HIV-infected individuals: United States-Latin Amer... - 0 views

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    The purpose of this Funding Opportunity Announcement (FOA) is to facilitate the design, conduct, and completion of clinical trials for improving prevention of human papillomavirus (HPV)-related cancers in human immunodeficiency virus (HIV)-infected individuals. To serve this goal, the FOA will support a network of international collaborative sites conducting meritorious and appropriately designed prevention clinical trials in the Latin American and Caribbean (LAC) region via a U54 Partnership Centers mechanism.
MiamiOH OARS

DoD Breast Cancer, Breakthrough Award Levels 3 and 4 - 0 views

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    Impact: Research supported by the Breakthrough Award will have the potential for a major impact and accelerate progress toward ending breast cancer. The impact may be near-term or long-term, but must move beyond a minor advancement and have the potential to lead to a new approach that is fundamentally better than interventions already approved or in clinical development. Applications are expected to identify the breast cancer patients or at-risk individuals who would ultimately benefit from the proposed research.
MiamiOH OARS

PA-18-818: Administrative Supplements for Validation Studies of Analytical Methods for ... - 0 views

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    The reproducibility and comparability of research on dietary supplements is enhanced by rigorous analytical characterization of key experimental materials and the publication of validated analytical methods that accurately and precisely characterized and quantify constituents in dietary supplement ingredients and products. This FOA builds on existing NIH awards to support the performance and publication of formal single-laboratory validation studies of quantitative analytical methods. The methods proposed for validation must be used to identify and quantify dietary supplement-relevant chemical constituents (i.e., active or marker chemical compounds, adulterants, contaminants) or their metabolites in experimental reagents, raw materials, and/or clinical specimens (e.g., urine or plasma samples). Methods must have been developed or utilized in fulfillment of the active parent grant's specific aims. Candidate constituents for quantitative method validation studies include (but are not limited to): phytochemicals, nutrients, and potentially deleterious substances such as pesticides and mycotoxins. Multi-laboratory validation studies will not be supported through this FOA.
MiamiOH OARS

Using Archived Data and Specimen Collections to Advance Maternal and Pediatric HIV/AIDS... - 0 views

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    The purpose of this Funding Opportunity Announcement (FOA) is to address the needs of the maternal and pediatric HIV scientific community for research data translation and sharing. This initiative will support secondary data analyses using archived HIV/AIDS data and specimens to generate new research questions and findings relevant to the scientific mission and priorities of the NICHD, Maternal and Pediatric Infectious Disease Branch (MPIDB) and Office of AIDS Research (OAR). The goal of this initiative is to encourage applicants to leverage existing datasets and employ new and advanced analysis techniques to answer scientific questions about the epidemiology, pathogenesis, treatment, clinical manifestations and complications of HIV/AIDS in maternal, pediatric and adolescent populations.
MiamiOH OARS

RFA-CA-18-013: Investigation of the Transmission of Kaposi Sarcoma-associated Herpesvir... - 0 views

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    The purpose of the funding opportunity announcement (FOA) is to advance our understanding of the modes of transmission of Kaposi sarcoma-associated herpesvirus (KSHV), also called human herpesvirus-8 (HHV-8); the biology of the initial steps of infection; and risk factors for infection to inform efforts to prevent KSHV transmission and thus prevent Kaposi sarcoma (KS), KSHV-associated multicentric Castleman disease (MCD), primary effusion lymphoma (PEL), and other KSHV-induced diseases in populations living with HIV or at high risk of developing HIV. This program covers two parallel FOAs of identical scientific scope. This FOA solicits applications for well-developed research projects using the NIH R01 funding mechanism. The companion FOA, RFA-CA-18-014, is a parallel announcement for exploratory/developmental projects using the NIH R21 mechanism.
MiamiOH OARS

Mark Foundation for Cancer Research Invites Proposals for Emerging Leaders Awards | RFP... - 0 views

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    The Mark Foundation for Cancer Research funds groundbreaking research that integrates discoveries in biology with innovative technology to deliver breakthroughs to patients. To advance this mission, the foundation is inviting proposals for its Emerging Leaders Awards program, which provides support to early-career investigators engaged in high-impact, high-risk cancer research. Through the annual program, the foundation will award three-year grants of $750,000. The award is intended to support projects for which other sources of funding are not readily available from traditional funding mechanisms or for a separate innovative endeavor that will enhance the PI's current research portfolio. Eligible applicants must hold an MD, PhD, MD/PhD, or the equivalent at a U.S. nonprofit academic institution and be within three to eight years of their initial independent appointment. In addition, applicants must have a demonstrated ability to obtain independent funding for their lab (e.g., one or two grants such as NIH/R01, NSF/CAREER, or equivalent multi-year awards).
MiamiOH OARS

LARGE-SCALE T CELL IMMUNE EPITOPE DISCOVERY - Federal Business Opportunities: Opportuni... - 0 views

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    The primary purpose of this solicitation is to support highly interactive, multi-disciplinary teams, whose research efforts are focused on large-scale discovery of T cell immune epitopes associated with infectious or autoimmune diseases, and rejection of, or tolerance to, transplanted cells/organs/tissues. The discovery of epitopes associated with T cell responses to commensals and how they may be altered by the inflammatory state will also be supported by this solicitation. Validation of these epitopes and defining their role in immune protection or immune-mediated pathogenesis in humans is required. Investigators may include development/refinement of T cell epitope prediction tools as part of their research plan. It is anticipated that the multi-disciplinary teams will minimally include immunologists with the appropriate expertise in epitope identification and validation, and either microbiologists and/or virologists with expertise in the target pathogen(s), clinicians with expertise in the target autoimmune diseases, or clinicians with expertise in transplantation, as appropriate. This program will not support studies related to HIV/AIDS, or allergen epitopes, including those which are infection-related.
MiamiOH OARS

PREVENT Cancer Preclinical Drug Development Program - Federal Business Opportunities: O... - 0 views

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    The purpose of this solicitation is to procure Research & Development services to support the PREVENT Program in the areas of (1) in vivo development/animal efficacy/biomarker development, (2) preclinical product development and CGMP manufacturing of biopharmaceutical agents, and (3) toxicology/pharmacology testing.
MiamiOH OARS

Understanding Skeletal Effects of Type 1 Diabetes (R01 Clinical Trial Optional) - 0 views

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    This Funding Opportunity Announcement (FOA) invites applications for studies to understand the effects of type 1 diabetes (T1D) on bone mass and quality and/or fracture risk. Researchers may propose investigations in newly recruited subjects or using subjects and/or samples from ongoing clinical studies of individuals with for T1D.
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