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The 2017 CDC STD Surveillance Report documented continued steep and sustained increases in the three reportable STDs - gonorrhea, chlamydia and syphilis. Congenital syphilis rates reached a 20-year high in 2017. Healthcare providers and health systems remain at the forefront of the battle against STDs. Provider education, technical assistance, and clinical capacity building are critical pieces for a foundation of comprehensive STD clinical prevention in healthcare settings. A dynamic and complex healthcare landscape demands innovative methods to reach both clinicians and healthcare settings from a variety of sectors throughout the U.S in order to meet the goal of optimal STD clinical prevention implementation in the clinical care setting. The purpose of this NOFO is to support The National Network of Sexually Transmitted Diseases Clinical Prevention Training Centers (NNPTC). This network is charged with improving the capacity of healthcare professionals, clinical sites and healthcare systems to employ state-of-the-art knowledge to diagnose, manage, treat and counsel individuals with and at-risk for STDs in order to reduce STD morbidity and improve sexual health on an individual, local and national level. This NOFO supports the following broad strategies : Component A Regional Centers: A1 (Core) - assess training needs and service gaps to inform the development and delivery of comprehensive STD clinical prevention T/TA for providers serving priority populations; A2 (Focus Activity) - pr

This FOA, issued by the Office of Medical Policy (OMP), Center for Drug Evaluation and Research, Food and Drug Administration, solicits grant applications from neutral, independent institutions and/or organizations to support meetings (e.g., conferences, workgroups, roundtables) that convene a broad range of multiple stakeholders, including those with relevant expertise, to explore and address issues related to medical products, policy, and surveillance methods and systems. Support includes but is not limited to preliminary research of identified topics, the design, planning, execution, synthesis, summary, and communication of findings from these forums to a broad range of organizations and individuals.

The intended outcome of this cooperative agreement is to advance the goal of a national food safety system by supporting and enhancing state food laboratories tasked with investigation of foodborne disease outbreaks in activities including: 1. Ensuring microbiological and chemical food analyses performed on behalf of the State manufactured food regulatory programs are conducted within the scope of an International Organization for Standardization (ISO)/ International Electrotechnical Commission (IEC) 17025 accredited laboratory; 2. Strengthening the collaboration between the laboratories and State manufactured food regulatory programs; 3. Increasing the number of State samples collected and analyzed for surveillance purposes annually; 4. Developing a stronger international rapid surveillance system for pathogen traceback through the GenomeTrakr network using a minimum set of metadata fields for all food and environmental isolates; and 5. Providing additional support to the State food laboratories through an outside association to offer trainings, workshops, and educational resources to both awardees under this cooperative agreement and to unfunded laboratories seeking ISO/IEC 17025 accreditation.

The purpose of this Funding Opportunity Announcement (FOA) is to establish a coordinated network of Emerging Infectious Disease Research Centers (EIDRCs) in regions around the globe where emerging and re-emerging infectious disease outbreaks are likely to occur. Multidisciplinary teams of investigators will conduct pathogen/host surveillance, study pathogen transmission, pathogenesis and immunologic responses in the host, and will develop reagents and diagnostic assays for improved detection for important emerging pathogens and their vectors.

The purpose of this cooperative agreement is: To conduct and monitor epidemiologic, clinical, and laboratory-based projects, surveillance, and research of important diseases in Liberia. To incorporate the results of research activities into operational disease detection, prevention, and response or control programs in Liberia and ensure the strengthening of local workforce capacity and dissemination of findings across the region, with partners, and globally.

The purpose of this NOFO is to better understand the public health and clinical impacts of living with MD by conducting longitudinal, population-based surveillance and research of eligible MDs (DMD, BMD, DM, FSHD, LGMD, CMD, EDMD, OPMD, and Distal MD). The current cycle will focus on identifying eligible MD cases, conducting longitudinal follow-up and research, analyzing data, and publishing and disseminating the results. Current MD STARnet sites will collect data to estimate prevalence and survival and additional clinical data on existing MD cohorts. New MD STARnet sites will focus on identifying eligible MD cases and collecting data to estimate prevalence, survival and track key clinical indicators. Identification of cases through population-based surveillance will enable existing and new sites to conduct research on these populations. This information is expected to advance understanding of diagnosed prevalence, disease progression and survival; clinical care and interventions and their alignment with recommended care; disparities in access to care; the association of treatment with outcomes, and the impact of MD on the lives of affected individuals and their families.

The purpose of this program is to support the development of population-based surveillance systems and data linkages for persons with congenital heart defects (CHDs) using non-research CDC cooperative agreements. An estimated 2 million persons in the United States are living with a CHD, yet little is known about their long-term outcomes. High-quality data will improve the public's understanding of the epidemiology and public health significance of CHDs. surveillance data will allow monitoring of special sub-populations with CHDs and potentially identify risk factors and prognostic factors for identifying opportunities and developing effective secondary prevention strategies directed at reducing the personal and public health impact of CHDs and improving the lives of individuals with a CHD. The planned objectives of this NOFO are: COMPONENT A: surveillance of CHDs among individuals aged 1-45 years through linkage of existing data sources 1) D

Respiratory syncytial virus (RSV) is the leading viral cause of lower respiratory tract infection including bronchiolitis and pneumonia in infants and children worldwide. The annual rate of RSV hospitalizations for children less than 2 years of age in the US is 5.2 per 1,000, but substantially higher among Native Americans. There are currently approximately 40 vaccines or antibody products in development designed to prevent RSV infections. With potential licensure of these products on the horizon, it will be important to establish baseline estimates of the burden of RSV infections in high-risk populations, like Native Americans, and to maintain surveillance post-licensure in order to evaluate impact. Native Americans are also at higher risk for severe respiratory infections associated with human metapneumovirus (HMPV) and other viruses, which will also be monitored through this system.

NIOSH uses cooperative agreements to arrange collaborative surveillance and research opportunities with state health departments, universities, labor unions, and nonprofit organizations. NIOSH funds a broad array of cooperative agreements to develop knowledge for preventing occupational diseases, injury, and death. The U24 cooperative agreement mechanism will be used to provide tribal nations, states, and large municipalities with technical assistance and services to build occupational safety and health (OSH) program capacity and promote the use of multiple-source surveillance data. The awardee(s) will advance education and translation through the operation of an open-access online repository for occupational health information and surveillance data. States, Non-governmental organizations (NGOs), and tribes will draw upon relationships with their stakeholders to use surveillance data to take action such as identify or support tribal and state priorities, and guide coordinated, targeted efforts to protect workers; monitor statistical and other trends and progress over time (i.e., burden and impact); propose pilot and evaluation activities for addressing disease burden or impact; conduct educational and outreach activities; and to develop prevention and intervention recommendations.

South Africa's has been making steady progress towards 90-90-90 targets, but these targets are unlikely to be attained without additional support and resources. The South African Department of Health developed an HIV Treatment and Retention Acceleration Plan (TRAP) in September 2017 to aggressively improve performance in the ART Program. CDC has been partnering with National Department of Health (NDoH) for several years through three consecutive cooperative agreements, 2003 to 2009, 2009 to 2014 and currently 2014 to 2019. This follow-on NOFO will allow CDC South Africa to continue to support and engage with the National Department of Health in developing and reviewing guidance and policy documents on HIV and TB, support surveys and surveillance activities to correctly characterize and describe the epidemic, provide guidance on evidence-based program implementation and coordinate monitoring and evaluation activities and other health systems interventions to assess effectiveness of interventions and program performance and ensure that health delivery systems are functional and structurally conducive to optimal HIV and TB service delivery.

During the last nine years, the U.S. Centers of Disease Control and Prevention (CDC) has worked with nations around the world to build capacity to prepare, detect, and respond to pandemics. Through previous funding opportunity announcements (FOA) and subsequent cooperative agreements, CDC and its international partners and national ministries of health focused on three pillars: 1) preparedness and communication; 2) surveillance and detection; 3) response and containment. The success of this developed capacity is evident across the globe. Through these cooperative agreements, CDC and partners have: Developed national government public-health pandemic preparedness plans Developed pandemic communication plans Improved laboratory capacity and infrastructure for influenza virologic surveillance Enhanced epidemiology capacity and infrastructure for disease surveillance Developed sentinel, hospital-based surveillance for severe acute respiratory illness (SARI) Enhanced integration of laboratory and epidemiologic surveillance for influenza Developed surveillance for cases and clusters of respiratory and febrile illnesses that could represent emerging new pandemics. Trained local rapid-response and containment teams. Developed infection control guidelines in public health-care settings for the prevention of avian and pandemic flu. It is critical that these new capacities be sustained and strengthened over time to ensure global capacity to detect and respond to pandemic influenza effectively.

This notice of funding opportunity supplemental expansion will support foreign governments through their ministries of health or other responsible entities for human health or public-health emergency preparedness in Azerbaijan, Bhutan, Bolivia, Columbia, Ecuador, Hashemite Kingdom of Jordan, Kyrgyzstan, the Maldives, Mali, Mozambique, Republic of Tunisia, and South East Europe (a multi-country proposal from Albania, Bosnia-Herzegovina, Macedonia, Montenegro). The principal purpose is this additional year of funding is to extend support of routine influenza surveillance and build capacity to respond to and contain a highly pathogenic virus transmissible among humans in the above-referenced countries. A second intent is to support the development of epidemiologic, virologic, and related capacity to detect, respond to, and monitor changes in influenza viruses, as well as identify outbreaks of severe respiratory illness syndromes. A third intent is to increase participation in the World Health Organization Global Influenza surveillance and Response System (GISRS) and capacity to share specimens and clinical/epidemiologic data on the circulation of influenza in the identified countries.

The purpose of this NOFO is to provide funding and technical assistance for PEPFAR countries to establish HIV recent infection surveillance to detect recent infections, monitor trends in the HIV epidemic, identify hot spots associated with recent HIV transmission, and inform programmatic interventions to reach epidemic control. Point-of-care tests for recent infection distinguish between recent (HIV seroconversion in the last 6 months, on average) and non-recent HIV infection and provide results within minutes. These data may be linked to HIV case-based surveillance for ongoing epidemic monitoring and used by programs to provide enhanced counselling for immediate ART initiation, prioritize index testing, and intervene to prevent HIV transmission. This NOFO will require a multi-disciplinary team with expertise in surveillance, laboratory, prevention, HIV testing services, health informatics, data management, data analytics, and supply chain to support the planning, implementation, and impact evaluation of this PEPFAR priority activity.

In 1994 the Centers for Disease Control and Prevention (CDC) collaborated with a broad range of partners in clinical medicine and public health to develop an emerging infections strategy in response to the recommendations issued by the Institute of Medicine (IOM) in its 1993 report, “Emerging Infections: Microbial Threats to Health in the United States.” Leading this strategy was the CDC Office of Infectious Diseases (OID)/National Center for Emerging and Zoonotic Infectious Diseases (NCEZID). One goal was to strengthen local, state, and federal public health infrastructures to support surveillance and implement prevention and control programs. The implementation strategy for this goal was to: 1) provide state-of-the-art training in diagnostic evaluation and testing for medical laboratory personnel to ensure the diagnosis and surveillance of emerging infections; and 2) establish a public health laboratory fellowship in infectious diseases that will train medical microbiologists in public health approaches to diagnosis and molecular epidemiology.

The Centers for Disease Control and Prevention (CDC) proposes to allocate funds to implement Notice of Funding Opportunity (NOFO) PS18-1807, “Promoting Adolescent Health through School-Based HIV/STD Prevention.” The project period will be 5 years, with a 12-month budget period and an anticipated award date of August 1, 2018. This NOFO will provide support for education agencies and NGOs to help school districts and schools develop and implement sustainable program activities to: 1) Reduce HIV infection and other STDs among adolescents; and 2) Reduce disparities in risk for HIV infection and other STD infection. Throughout the 5-year cooperative agreement, awardees will conduct activities demonstrated to improve the health of middle school and high school students by collection and use of quality surveillance data, the implementation of effective prevention practices, and demonstration and evaluation of innovative strategies within their jurisdictions.

ntiretroviral therapy has been recommended for all persons living with HIV since 2012. However, in 2014, among persons with diagnosed HIV infection, 57.9% of all persons were virally suppressed and 48.1% of youth were virally suppressed (https://www.cdc.gov/hiv/pdf/library/reports/surveillance/cdc-hiv-surveillance-supplemental-report-vol-22-2.pdf ). Insurers have information on clinical encounters which provide them with diagnoses codes. They also have information on pharmacy claims data and can assess if persons with a diagnosis of HIV are receiving antiretroviral (ARV) drugs.

The purpose of this NOFO is to support a more efficient method for HIV surveillance jurisdictions to identify potential interstate duplicates. The recipient will develop and provide a secure, encrypted, on-going privacy data-sharing tool capable of identifying potential duplicates across jurisdictions, implement necessary data security, confidentiality and privacy protections according to CDC standards, obtain participation agreements with 59 state and local health department HIV surveillance programs that will allow on demand submission and matching of person-level HIV surveillance data, and report back to jurisdictions on matching levels in formats that are importable into local/state HIV data systems.

In Uganda, key and priority populations (KP/PP) have a higher prevalence of HIV and more difficulties accessing prevention and care services. This NOFO will improve the development, implementation, and monitoring of accessible, appropriate, and targeted HIV combination prevention for KP/PP in Uganda. This NOFO will result in an increased use of these services by KP/PP, which will result in these high risk sub-populations attaining the 90-90-90 goals and achieving epidemic control by 2020. The recipient will provide technical assistance (TA) to CDC comprehensive regional implementing partners (IPs) on developing, monitoring, and evaluating new ways to provide combination prevention to KP/PP; implementing and evaluating a nationwide training on gender and sexual identity; and cascading a KP training nationwide to health workers to reduce stigma and discrimination. Strategic information (SI) activities, including improving the collection of routine surveillance data, mapping KP/PP hotspots, and evaluating interventions will support the development and implementation of accessible, appropriate, targeted combination prevention for KP/PP. The recipient will support the Ugandan Ministry of Health (MOH) to improve surveillance of HIV in KP/PP (including population size estimates and bio-behavioral studies) and develop comprehensive guidelines for service provision to KP/PP.

The purpose of the Tanzania Malaria Surveillance and Monitoring (TMSM) Cooperative Agreement is to support the Government of Tanzania to reduce the burden of malaria and to move towards the long-term goal of malaria elimination.

This NOFO will support achievement of national targets for 2018 antiretroviral therapy (ART) scale-up towards the UNAIDS Fast Track Targets in Ukraine. The recipient will implement innovative and effective recruitment and case management models for persons who inject drugs (PWID) and men who have sex with men (MSM) at the community level. These innovative changes will increase uptake of HIV community based testing and increase ART initiation for these populations. The recipient will pilot risk network-based testing using point-of-care recency assays to link recently infected PWID to care. The project will focus on the six regions with the highest HIV burden (Dnipropetrovsk, Mykolayiv, Odesa, government controlled areas (GCA) of Donetsk, Kyiv City, and Kherson) and continue to work in six additional medium burden oblasts (Cherkasy, Poltava, Chernihiv, Zaporizhzhya, Kirovohrad, and Kyiv). The recipient will also increase the capacity of the Government of Ukraine’s Center for Public Health (CPH) and regional monitoring and evaluation (M&E) centers specialists to conduct data analysis using statistical software and build institutional capacity to conduct economic evaluations of HIV interventions. Illustrative strategic information (SI) activities include development of trainings to support the Ministry of Health (MOH) and the newly established CPH in using statistical software, routine analysis of surveillance data, study design, and research protocol development.