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This award is intended to stimulate the entry of early-career scientists into areas of research related to eczema, as they seek to become an independent research investigator with a commitment to this field. Catalyst Research Grants provide promising early investigators with seed grants to help establish a novel and promising line of eczema research, and gather a preliminary, yet meaningful body of data to carry this area of study forward. Data from Catalyst awards can then be used to seek additional, larger-scale funding from the National Institutes of Health (NIH) or other funding entities to conduct additional investigations. Proposals should address at least one of the following research priorities: Cutting Edge Basic & Translational Science* Eczema Heterogeneity: Novel Insights Innovations in Clinical Practice & Care Understanding & Alleviating Disease Burden Eczema Prevention

This Funding Opportunity Announcement (FOA) invites exploratory/developmental applications that propose transformative engineering solutions to technical challenges associated with meaningful development, substantial optimization of existing technologies and clinical translation of intraoral biodevices. Proposed technologies are expected to advance development of oral biodevices to clinical use, including but not limited to: precision medicine-based detection, diagnosis and treatment of oral and overall health conditions, and measurement of patient functional status and clinical outcome assessment. Areas of interest in this FOA include engineering approaches that allow integration of electronic, physical, and biological systems essential to the development of functional biodevices that are safe and effective for detection, diagnosis and treatment of oral and systemic disease. Products of this research will be proof-of-concept prototype biodevices, dedicated biosensors and associated core technologies that enable development of safe and effective intra-oral biodevices intended for specific clinical applications. To streamline the development of oral biodevices that advance precision medicine-based approaches in clinical practice, this FOA encourages interdisciplinary collaborations across engineering, multifunctional sensors, pharmacology, chemistry, medicine, and dentistry, as well as between academia and industry.

The AWS Diagnostic Development Initiative supports AWS customers who are working to bring better, more accurate diagnostic solutions to market faster. Given the need, the emphasis initially will be on COVID-19, but we will also consider other infectious disease diagnostic projects. The program will be open to accredited research institutions, research consortia, and private entities, that are using AWS to support research-oriented workloads for the development of point-of-care diagnostic (testing that can be done at home or at a clinic with same-day results) and other diagnostic techniques. We will not support administrative workloads to run routine IT operations through this program.

The Rheumatology Research Foundation is issuing a notice of special interest (NOSI) to highlight the availability of funds for projects exploring the relationships between rheumatic and musculoskeletal diseases and SARS-CoV-2, the virus that causes COVID-19. The Foundation accepts submissions within the following scientific categories: * Basic Science * Translational Science * Clinical Science * Health Services Research * Patient- or Practice-Centered Research Examples of studies relevant to this NOSI include, but are not limited to: * Immune responses to SARS-CoV-2 and pathogenesis of COVID-19 in patients with RMDs * Influence of DMARDs, biologic agents, or other medications, on SARS-CoV-2 immune responses * Studies of DMARDs or biologic agents used in RMDs on outcomes of SARS-CoV2 infection in animal models or in vitro * Epidemiology, clinical characteristics, and outcomes of CoVID-19 course in patients with RMDs, including the influence of therapeutic agents or other interventions in pragmatic trials * The effects of COVID-19 on access to rheumatology care, including telehealth, digital tools, social determinants of health, etc. * Analyses of the economic impact of COVID-19 on the care of patients with RMDs

To support generation of single cell RNA-sequencing data sets for at least one brain region relevant to persistent HIV infection and opioid, cocaine and/or methamphetamine use disorder

Through this Funding Opportunity Announcement (FOA), the National Cancer Institute (NCI) as a part of its Beau Biden Cancer Moonshot Initiative invites submission of applications requesting support for projects that will accelerate cancer research. Specifically, this FOA targets the following area designated as a scientific priority by the Blue Ribbon Panel (BRP) as Recommendation I: Generation of Human Tumor Atlases. The overarching goal of this FOA is to accelerate research efforts conducted and led by the Human Tumor Atlas Network (HTAN, humantumoratlas.org) via the implementation of three-dimensional (3D) imaging technologies that will allow for a comprehensive view of the dynamic multidimensional ecosystems that define tumors in humans. Each project will lead to the multiplexed 3D characterization of at least one cancer transition investigated by the HTAN (pre-malignant to malignant, primary to metastatic, therapy responsive to resistant). The data and analytical tools generated through this FOA will be made available for use by the research and clinical communities through the activities of the HTAN Data Coordinating Center.

The Law & Science Program considers proposals that address social scientific studies of law and law-like systems of rules, as well as studies of how science and technology are applied in legal contexts. The Program is inherently interdisciplinary and multi-methodological. Successful proposals describe research that advances scientific theory and understanding of the connections between human behavior and law, legal institutions, or legal processes; or the interactions of law and basic sciences, including biology, computer and information sciences, STEM education, engineering, geosciences, and math and physical sciences. Scientific studies of law often approach law as dynamic, interacting with multiple arenas, and with the participation of multiple actors. Fields of study include many disciplines, and often address problems including, though not limited, to: Crime, Violence, and Policing Cyberspace Economic Issues Environmental Science Evidentiary Issues Forensic Science Governance and Courts Human Rights and Comparative Law Information Technology Legal and Ethical Issues related to Science Legal Decision Making Legal Mobilization and Conceptions of Justice Litigation and the Legal Profession Punishment and Corrections Regulation and Facilitation of Biotechnology (e.g., Gene Editing, Gene Testing, Synthetic Biology) and Other Emerging Sciences and Technologies Use of Science in the Legal Processes

The NSF ADVANCE program provides grants to enhance the systemic factors that support equity and inclusion and to mitigate the systemic factors that create inequities in the academic profession and workplaces. Systemic (or organizational) inequities may exist in areas such as policy and practice as well as in organizational culture and climate. For example, practices in academic departments that result in the inequitable allocation of service or teaching assignments may impede research productivity, delay advancement, and create a culture of differential treatment and rewards. Similarly, policies and procedures that do not mitigate implicit bias in hiring, tenure, and promotion decisions could lead to women and racial and ethnic minorities being evaluated less favorably, perpetuating historical under-participation in STEM academic careers and contributing to an academic climate that is not inclusive. All NSF ADVANCE proposals are expected to use intersectional approaches in the design of systemic change strategies in recognition that gender, race and ethnicity do not exist in isolation from each other and from other categories of social identity. The solicitation includes four funding tracks: Institutional Transformation (IT), Adaptation, Partnership, and Catalyst, in support of the NSF ADVANCE program goal to broaden the implementation of systemic strategies that promote equity for STEM faculty in academic workplaces and the academic profession.

The COVID-19 pandemic has highlighted the need for improved environmental sensing of pathogens. Sensing SARS-CoV-2 virus in the air with high sensitivity and specificity could provide a new mechanism for public health monitoring, enabling safer conditions for a wide range of basic activities including work, travel, and school. SenSARS aims to identify SARS-CoV-2 signatures suitable for rapid indoor air monitoring and use these signatures to develop and demonstrate a technology readiness level (TRL) 4 prototype sensor.

The Small Business Innovation Research (SBIR) Program stimulates technological innovation in the private sector by strengthening the role of small business concerns in meeting Federal research and development needs, increasing the commercial application of federally supported research results, and fostering and encouraging participation by socially and economically disadvantaged and women-owned small businesses. The SBIR program solicits proposals from the small business sector consistent with NSF's mission. The program is governed by Public Law 112-81 (SBIR/STTR Reauthorization Act of 2011). A main purpose of the legislation is to stimulate technological innovation and increase private sector commercialization. The NSF SBIR program is therefore in a unique position to meet both the goals of NSF and the purpose of the SBIR legislation by transforming scientific discovery into both social and economic benefit, and by emphasizing private sector commercialization. Accordingly, NSF has formulated broad solicitation topics for SBIR that conform to the high-technology investment sector's interests. The topics are: Biological and Chemical Technologies (BC) Education Applications (EA) Electronics, Information and Communication Technologies (EI) Nanotechnology, Advanced Materials, and Manufacturing (NM)

The Geobiology and Low-Temperature Geochemistry Program supports research on 1) the interactions between biological and geological systems at all scales of space and time; 2) geomicrobiology and biomineralization processes; 3) the role of life in the transformation and evolution of the Earth's geochemical cycles; 4) inorganic and organic geochemical processes occurring at or near the Earth's surface now and in the past, and at the broad spectrum of interfaces ranging in scale from planetary and regional to mineral-surface and supramolecular; 5) mineralogy and chemistry of soils and sediments; 6) surficial chemical and biogeochemical systems and cycles and their modification through natural and anthropogenic change; and 7) development of tools, methods, and models for low-temperature geochemistry and geobiological research - such as those emerging from molecular biology - in the study of the terrestrial environment.

The Linguistics Program supports basic science in the domain of human language, encompassing investigations of the grammatical properties of individual human languages, and of natural language in general. Research areas include syntax, semantics, morphology, phonetics, and phonology. The program encourages projects that are interdisciplinary in methodological or theoretical perspective, and that address questions that cross disciplinary boundaries, such as (but not limited to): What are the psychological processes involved in the production, perception, and comprehension of language? What are the computational properties of language and/or the language processor that make fluent production, incremental comprehension or rapid learning possible? How do the acoustic and physiological properties of speech inform our theories of language and/or language processing? What role does human neurobiology play in shaping the various components of our linguistic capacities? How does language develop in children? What social and cultural factors underlie language variation and change?

The purpose of this Dear Colleague Letter is to advise you about funding opportunities at the National Science Foundation for the research community to propose research projects or workshops that will gather data on the implementation and impacts of recent science policy initiatives including, but not limited to those noted earlier.  Especially encouraged are proposals that will: Develop new, or improve existing, analytical frameworks for evaluating the impacts of federal science policy initiatives; Explore different agencies' approaches to the implementation of particular policies to examine how variations in approach affect the achievement of intended policy outcomes; Collect case-study or quantitative data that facilitate identification of best practices in science and innovation policy implementation.

The INSPIRE awards program was established to address some of the most complicated and pressing scientific problems that lie at the intersection of traditional disciplines.  It is intended to encourage investigators to submit bold, exceptional proposals that some may consider to be at a disadvantage in a standard NSF review process; it is not intended for proposals that are more appropriate for existing award mechanisms.

The purpose of this FOA is to support projects investigating the interplay between molecular regulation of brain energy utilization and brain and/or behavioral changes resulting from chronic exposure to abused substances.    

The purpose of this FOA is to support projects investigating the interplay between molecular regulation of brain energy utilization and brain and/or behavioral changes resulting from chronic exposure to abused substances.   

CAREER: The Faculty Early Career Development (CAREER) Program is a Foundation-wide activity that offers the National Science Foundation's most prestigious awards in support of junior faculty who exemplify the role of teacher-scholars through outstanding research, excellent education and the integration of education and research within the context of the mission of their organizations. Such activities should build a firm foundation for a lifetime of leadership in integrating education and research. NSF encourages submission of CAREER proposals from junior faculty members at all CAREER-eligible organizations and especially encourages women, members of underrepresented minority groups, and persons with disabilities to apply.

The Division of Integrative Organismal Systems (IOS) supports research aimed at understanding why organisms are structured the way they are and function as they do. Proposals should focus on organisms as a fundamental unit of biological organization. Principal Investigators (PIs) are encouraged to apply systems approaches that will lead to conceptual and theoretical insights and predictions about emergent organismal properties.  Areas of inquiry include, but are not limited to, developmental biology and the evolution of developmental processes, nervous system development, structure, and function, physiological processes, functional morphology, symbioses, interactions of organisms with biotic and abiotic environments, and animal behavior.

The National Institute on Drug Abuse (NIDA) supports a program of longitudinal cohorts to address emerging and high priority research on HIV/AIDS in the context of injection and non-injection substance abuse.  These cohorts provide a strong resource platform for current and future collaborative efforts with other investigators to address emerging questions related to HIV pathogenesis, prevention, and treatment in the context of substance abuse, as well as to foster the creativity and efficiency of investigator-initiated research projects. The diverse research activities among these cohorts include basic immunologic, and virologic studies, as well as studies on HIV prevention and treatment, and the co-morbidities and co-infections associated with HIV and substance abuse.  NIDA has determined that a coordinating center (CC) is needed in order to take advantage of these rich sources of data and bio-specimens and optimize collaborations among both the cohort investigators and other researchers not funded under the cohort program. In addition, the CC is expected to establish a virtual repository, and facilitate the leadership of the cohorts steering committee (SC), consisting of representatives from the NIDA-funded cohorts and NIDA staff. At this time, NIDA is soliciting  cooperative agreement applications for a CC to support the collaborative efforts of the cohorts that are currently funded by NIDA.

The Centers of Excellence on Environmental Health Disparities (EHD) research program is a collaborative effort supported by the National Institute on Minority Health and Health Disparities (NIMHD), the National Institute of Environmental Health Sciences (NIEHS), and the U.S. Environmental Protection Agency (EPA) that encourages basic, biological, clinical, epidemiological, behavioral and/or social scientific investigations of disease conditions that are known to be a significant burden in low socioeconomic and health disparate populations. The centers define environmental health disparities as inequities in illnesses that are mediated by disproportionate exposures associated with the social, natural and built environments. The kick-off meeting will feature presentations from each of the five funded centers highlighting their proposed research.