Today, after close to 6000 years of folklore, scientific research shows that garlic is an amazing resource of phytochemicals (botanicals) whose wide range of actions can benefit health. Studies show that garlic protects against infection and inflammation, lowers the risk of heart disease, and has anticancer and antiaging effects. Scientific studies also show that garlic does not have to be eaten raw or fresh to be effective. The potent odor of garlic may not be necessary for its health benefits. Research shows that aged, deodorized garlic extract sometimes works even better than fresh garlic without causing digestive disorders and "garlic breath" that may haunt the fresh garlic eater.
Glucose restriction can extend normal cell lifespan and impair precancerous cell growth through epigenetic control of hTERT and p16 expression.
Li Y, Liu L, Tollefsbol TO.
FASEB J. 2009 Dec 17. [Epub ahead of print]
PMID: 20019239
doi: 10.1096/fj.09-149328
Cancer cells metabolize glucose at elevated rates and have a higher sensitivity to glucose reduction. However, the precise molecular mechanisms leading to different responses to glucose restriction between normal and cancer cells are not fully understood. We analyzed normal WI-38 and immortalized WI-38/S fetal lung fibroblasts and found that glucose restriction resulted in growth inhibition and apoptosis in WI-38/S cells, whereas it induced lifespan extension in WI-38 cells. Moreover, in WI-38/S cells glucose restriction decreased expression of hTERT (human telomerase reverse transcriptase) and increased expression of p16(INK4a). Opposite effects were found in the gene expression of hTERT and p16 in WI-38 cells in response to glucose restriction. The altered gene expression was partly due to glucose restriction-induced DNA methylation changes and chromatin remodeling of the hTERT and p16 promoters in normal and immortalized WI-38 cells. Furthermore, glucose restriction resulted in altered hTERT and p16 expression in response to epigenetic regulators in WI-38 rather than WI-38/S cells, suggesting that energy stress-induced differential epigenetic regulation may lead to different cellular fates in normal and precancerous cells. Collectively, these results provide new insights into the epigenetic mechanisms of a nutrient control strategy that may contribute to cancer therapy as well as antiaging approaches.
Healthy Aging: A Lifelong Guide to Your Well-Being (Paperback)\nby Andrew Md Weil \nPaperback: 368 pages\nPublisher: Anchor (January 2, 2007)\nLanguage: English\nISBN-10: 0307277542\nISBN-13: 978-0307277541\n
Dr. Milne presented data which showed that SRT501, Sirtris' proprietary formulation of resveratrol, reduces glucose and improves insulin sensitivity in multiple pre-clinical models of Type 2 Diabetes. Dr. Milne also presented pharmacokinetic (PK) data fro
The Harvard Alumni Association in partnership with the Harvard Medical School presented this two-day Alumni College seminar highlighting the latest research on cancer, nutrition and dieting, exercise, and stress management.
The Harvard Alumni Association in partnership with the Harvard Medical School presented this two-day Alumni College seminar highlighting the latest research on cancer, nutrition and dieting, exercise, and stress management.
ScienceDaily (Aug. 10, 2009) - Next time you're making a cuppa, new research shows it might be wise to opt for a white tea if you want to reduce your risk of cancer, rheumatoid arthritis or even just age-associated wrinkles. Researchers from Kingston University teamed up with Neal's Yard Remedies to test the health properties of 21 plant and herb extracts. They discovered all of the plants tested had some potential benefits, but were intrigued to find white tea considerably outperformed all of them.
Its been two days in Oprah aired her special about the amazing anti-aging and weight loss properties of Resveratrol and the results have been amazing. We have had over 500 requests for our free sample bottle of Resveratrol and every day demand continues to grow.
Many of our visitors didn't seem to know that Resveratrol not only will give you loads of energy and promote younger looking skin, but it also is amazing for weight loss. As Dr.Oz said on Oprah just a few days ago Resveratrol promotes Calorie restriction naturaly. This means that just by taking a reveratrol supplement or by drinking 12 bottles of red wine a day. You can help promote natural weightloss with one simple pill, its really just that simple. But don't just take our word for it. See what Dr.Oz said about Resveratrol Here.
Calorie Restriction Diet Plan is being promoted by many medical experts to maintain body weight and size. Calorie restriction diet seems to be one of the most popular diets and it seems to be backed up by great medical results. This is different from fads