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Tero Toivanen

Scientists capture the first image of memories being made - 0 views

  • A new study by researchers at the Montreal Neurological Institute and Hospital (The Neuro), McGill University and University of California, Los Angeles has captured an image for the first time of a mechanism, specifically protein translation, which underlies long-term memory formation. The finding provides the first visual evidence that when a new memory is formed new proteins are made locally at the synapse - the connection between nerve cells - increasing the strength of the synaptic connection and reinforcing the memory. The study published in Science, is important for understanding how memory traces are created and the ability to monitor it in real time will allow a detailed understanding of how memories are formed.
  • research has focused on synapses which are the main site of exchange and storage in the brain.
  • They form a vast but also constantly fluctuating network of connections whose ability to change and adapt, called synaptic plasticity, may be the fundamental basis of learning and memory.
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  • Using a translational reporter, a fluorescent protein that can be easily detected and tracked, we directly visualized the increased local translation, or protein synthesis, during memory formation.
  • Importantly, this translation was synapse-specific and it required activation of the post-synaptic cell, showing that this step required cooperation between the pre and post-synaptic compartments, the parts of the two neurons that meet at the synapse.
  • This study provides evidence that a mechanism that mediates this gene expression during neuronal plasticity involves regulated translation of localized mRNA at stimulated synapses.
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    A new study by researchers at the Montreal Neurological Institute and Hospital (The Neuro), McGill University and University of California, Los Angeles has captured an image for the first time of a mechanism, specifically protein translation, which underlies long-term memory formation.
Tero Toivanen

First Evidence That Musical Training Affects Brain Development In Young Children - 0 views

  • The findings, published today (20 September 2006) in the online edition of the journal Brain [1], show that not only do the brains of musically-trained children respond to music in a different way to those of the untrained children, but also that the training improves their memory as well. After one year the musically trained children performed better in a memory test that is correlated with general intelligence skills such as literacy, verbal memory, visiospatial processing, mathematics and IQ.
  • Researchers have found the first evidence that young children who take music lessons show different brain development and improved memory over the course of a year compared to children who do not receive musical training.
  • While previous studies have shown that older children given music lessons had greater improvements in IQ scores than children given drama lessons, this is the first study to identify these effects in brain-based measurements in young children.
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  • The researchers chose children being trained by the Suzuki method for several reasons: it ensured the children were all trained in the same way, were not selected for training according to their initial musical talent and had similar support from their families. In addition, because there was no early training in reading music, the Suzuki method provided the researchers with a good model of how training in auditory, sensory and motor activities induces changes in the cortex of the brain.
  • Analysis of the MEG responses showed that across all children, larger responses were seen to the violin tones than to the white noise, indicating that more cortical resources were put to processing meaningful sounds. In addition, the time that it took for the brain to respond to the sounds (the latency of certain MEG components) decreased over the year. This means that as children matured, the electrical conduction between neurons in their brains worked faster.
  • Of most interest, the Suzuki children showed a greater change over the year in response to violin tones in an MEG component (N250m) related to attention and sound discrimination than did the children not taking music lessons.
  • Analysis of the music tasks showed greater improvement over the year in melody, harmony and rhythm processing in the children studying music compared to those not studying music. General memory capacity also improved more in the children studying music than in those not studying music.
  • The finding of very rapid maturation of the N250m component to violin sounds in children taking music lessons fits with their large improvement on the memory test. It suggests that musical training is having an effect on how the brain gets wired for general cognitive functioning related to memory and attention.
  • It is clear that music is good for children's cognitive development and that music should be part of the pre-school and primary school curriculum.
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    Researchers have found the first evidence that young children who take music lessons show different brain development and improved memory over the course of a year compared to children who do not receive musical training.
Tero Toivanen

» Working Memory Training can Influence Brain Biochemistry   « Brain Fitness Revolution at SharpBrains - 0 views

  • The major finding was that increased working memory capacity following training was associated with changes in brain biochemistry. Specifically, the researchers found changes in the density and binding potential of cortical D1 dopamine receptors in brain regions that are activated during working memory tasks.
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    The major finding was that increased working memory capacity following training was associated with changes in brain biochemistry. Specifically, the researchers found changes in the density and binding potential of cortical D1 dopamine receptors in brain regions that are activated during working memory tasks.
Tero Toivanen

http://www.sciencedaily.com/releases/2009/12/091223125125.htm - 1 views

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    Scientists at UC Santa Barbara have made a major discovery in how the brain encodes memories. The finding, published in the December 24 issue of the journal Neuron, could eventually lead to the development of new drugs to aid memory.
Tero Toivanen

Memory Improved 20% by Nature Walk « PsyBlog - 0 views

  • Marc G. Berman and colleagues at the University of Michigan wanted to test the effect of a walk’s scenery on cognitive function (Berman, Jonides & Kaplan, 2008; PDF).
  • In the first of two studies participants were given a 35 minute task involving repeating loads of random numbers back to the experimenter, but in reverse order.
  • The results showed that people’s performance on the test improved by almost 20% after wandering amongst the trees. By comparison those subjected to a busy street did not reliably improve on the test.
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  • In the second study participants weren’t even allowed to leave the lab but instead some stared at pictures of natural scenes while others looked at urban environments. The improvements weren’t quite as impressive as the first study, but, once again, the trees and fields beat the roads and lampposts.
  • These results replicated a previous study by Berto (2005) who found that just viewing pictures of natural scenes had a restorative effect on cognitive function.
  • So just as we might have predicted nature is a kind of natural cognitive enhancer, helping our brain let off steam so it can cruise back up to full functioning.
  • When our minds need refreshing and if natural scenery is accessible, we should take the opportunity. If not then just looking at pictures of nature is a reasonable second best.
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    New study finds that short-term memory is improved 20% by walking in nature, or even just by looking at an image of a natural scene.
Tero Toivanen

Mnemonics and memory improvement / Pegging and memory - 0 views

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    The system of pegging that I will be outlining over the course of the next few pages, is one of the most important techniques that has so far been developed in the field of Mnemonics, since the discipline was first practised during the time of the ancient Greeks.
Tero Toivanen

Neurophilosophy : The neurological basis of intuition - 0 views

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    According to a new study, our gut feelings can enhance the retrieval of explicitly encoded memories. Eksplisiittisen ja implisiittisen muistitiedon käsittely aivoissa.
Tero Toivanen

YouTube - Man without a memory - Clive Wearing [BBC - Time: Daytime] - 3 views

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    Man who don't have memory and is constantly living in the present moment.
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    I love that ' bump up against' people and ideas counter to those which we' ve previously aligned-that' s kind of how I see aging gracefully-being able to see many more and others viewpoints-otherwise aging can seem like becoming caricatures of ourselves-we so believe our own thoughts (beliefs are after all only our much/most repeated thoughts!) and there' s no room for anyone or anything else! Mmmmmm yeah but now to live it!
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    My mother had a stroke and now she has big problems to communicate. She understands allmost everything, but have great problems to express herself speaking. Aging is not easy thing if you have problems with your health.
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    Truly! It' s alot slower to align with our preferences for sure when sick. I sincerely recommend www.bruno-groening.org as a resource The Bruno Groning Circle of Friends-all volunteers!. It' s a type of Faith healing that I recognise as quite remarkable. It has strong old world Germanic Christian vibe and/but dont let that put you off the ' healing stream' which is very easy to teach to yourself/your mother and available to all regardless of religious affliations.
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    Thak you for the link : )
David McGavock

Scientific Understanding of Consciousness - 0 views

  • During the past 20 years or so, biological sciences have advanced to the point that scientists have begun researching biological mechanisms of brain function and suggesting some reasonably well-founded hypotheses for consciousness. Leading the way in these pioneering efforts, in my judgment, have been:   Gerald Edelman with his hypothesis of the Dynamic Core, Antonio Damasio with his concepts of  Protoself, Core Self, Autobiographical Self, Core Consciousness and Extended Consciousness, Joseph LeDoux and his emphasis on the intricacies of synapses and the emotional brain,
  • Rudolfo Llinás and his researches into ~40 Hz oscillations and synchronization, György Buzsáki with his discussion and exploration of neural mechanisms related to oscillation and synchronization in the neocortex and hippocampus for perception and memory, Joaquín Fuster, the world’s preeminent expert on the frontal lobes, and his concept of the "perception-action cycle," Susan Greenfield's notion of "neuronal gestalts" as a way of conceptualizing a highly variable aggregation of neurons that is temporarily recruited around a triggering epicenter. I use the neuronal gestalts idea in my way of visualizing the functionality of the dynamic core of the thalamocortical system, Eric Kandel who has explored short-term and long-term memory,
  • The late Francis Crick with his collaborator Christof Koch who have pursued the neural correlate of consciousness (NCC), Michael Gazzaniga with the concept of the left hemisphere ‘interpreter’ unifying consciousness experience, Edmund Rolls and Gustavo Deco with their mathematical models of brain function using information theory approaches for biologically plausible neurodynamical modeling of cognitive phenomena corroborated by brain imaging studies, David LaBerge with his discussion of the thalamocortical circuit and attention, Alan Baddeley who continues to refine his model for working memory, Philosopher John Searle who endorses the idea that consciousness is an emergent property of neural networks.
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    "My objective in this website has been to bring together salient features of these assorted interpretations by science experts into a synthesis of my own understanding of consciousness. I consider these statements and interpretations to be a framework on which to build a fuller understanding as further data, concepts and insights develop from ongoing research."
Tero Toivanen

How To Keep Mentally Fit As You Age | Boost Your IQ - 0 views

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    When you are young and mentally fit, you will perhaps never be able to comprehend that your memory, intelligence and overall mental fitness can actually decline as you age. However, as we grow older, our mental sharpness will gradually decline (and at an increasing rate) if we fail to keep on top of things.
Tero Toivanen

Let me sleep on it: Creative problem solving enhanced by REM sleep - 0 views

  • "Participants grouped by REM sleep, non-REM sleep and quiet rest were indistinguishable on measures of memory," said Cai. "Although the quiet rest and non-REM sleep groups received the same prior exposure to the task, they displayed no improvement on the RAT test. Strikingly, however, the REM sleep group improved by almost 40 percent over their morning performances."
  • The study by Sara Mednick, PhD, assistant professor of psychiatry at UC San Diego and the VA San Diego Healthcare System, and first author Denise Cai, graduate student in the UC San Diego Department of Psychology, shows that REM directly enhances creative processing more than any other sleep or wake state. Their findings will be published in the June 8th online edition of the Proceedings of the National Academy of Sciences (PNAS).
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    "Participants grouped by REM sleep, non-REM sleep and quiet rest were indistinguishable on measures of memory," said Cai. "Although the quiet rest and non-REM sleep groups received the same prior exposure to the task, they displayed no improvement on the RAT test. Strikingly, however, the REM sleep group improved by almost 40 percent over their morning performances."
Tero Toivanen

Neurophilosophy : Experience induces global reorganization of brain circuitry - 0 views

  • Now referred to as long-term potentiation (LTP), this mechanism has since become the most intensively studied in modern neuroscience,and is widely believed to be the cellular basis of learning and memory, although this is yet to be proven unequivocally.
  • In the new study, Santiago Canals of the Max Planck Institute for Biological Cybernetics in Tübingen and his colleagues used the same protocol to induce LTP. But while the vast majority of researchers have investigated LTP in slices of hippocampal tissue, this study involved observing LTP in live animals.
  • This new research provides the first evidence that the local modifications in synaptic connections induced by LTP lead to long-lasting changes in the activity of a diffuse network of brain regions, and even to facilitated communication between the two hemispheres. The fMRI data showed that hippocampal LTP recruits higher order association areas, as well as regions involved in emotions and others subserving different sensory modalities, all of which are known to be involved in memory formation.
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    Experience induces global reorganization of brain circuitry. This new research provides the first evidence that the local modifications in synaptic connections induced by LTP lead to long-lasting changes in the activity of a diffuse network of brain regions, and even to facilitated communication between the two hemispheres.
Tero Toivanen

Jeff Hawkins on how brain science will change computing | Video on TED.com - 0 views

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    Treo creator Jeff Hawkins urges us to take a new look at the brain -- to see it not as a fast processor, but as a memory system that stores and plays back experiences to help us predict, intelligently, what will happen next.
Tero Toivanen

The Teaching Company Free Lectures - 0 views

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    Excellent video lecture about learning, memory and brain by Jeanette Norden Ph.D. from Vanderbit University.
Tero Toivanen

How The Memory Works In Learning - 3 views

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    "This introduction to the basics of the neuroscience of learning includes information that should be included in all teacher education programs. It is intentionally brief such that it can be taught in a single day of instruction."
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    Very nice - simple summary for teachers.
Tero Toivanen

Cognitive Daily: A quick eye-exercise can improve your performance on memory tests (but only if you're right-handed) - 0 views

  • If you're taking a test of rote memorization, like words from a list, move your eyes from side to side for about 30 seconds before you start.
  • It may be that this quick activity helps facilitate interaction between the brain hemispheres.
  • any activity that encourages communication between the hemispheres is likely to increase recall.
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  • people who have poorer interactions between the hemispheres should benefit more than others. Who has less interactions between hemispheres? People who are strongly right-handed.
  • Strongly right-handed students remembered significantly more words if they moved their eyes compared to keeping their eyes still. Non-strongly-right-handed students (including left-handers) remembered the same number of words regardless of whether they moved their eyes before the test.
  • strongly right-handed students had significantly fewer false alarms after they moved their eyes back and forth. But for non-strongly-right-handed people, the reverse occurred; moving their eyes caused them to falsely remember more words. So overall, while the eye-saccade exercise helped right-handers, for lefties and for those who didn't have a strongly dominant hand, the exercise actually harmed their performance.
  • You might think that only side-to-side movement would improve performance, but Lyle's team found that moving your eyes up and down caused the same effect.
  • researchers say that other studies have shown that any eye movements increase bilateral activity in the frontal eye field, so it's still possible that hemispheric connectivity can explain the improved performance after eye movements.
  • So why doesn't the exercise work the same way for left-handers? Left handers (and ambidextrous individuals) already have a high level of hemispheric connectivity. Lyle's team speculates that there might be such a thing as too much connectivity, which results in a decrease in performance.
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    Several studies have confirmed this bizarre proposition: If you're taking a test of rote memorization, like words from a list, move your eyes from side to side for about 30 seconds before you start.
Tero Toivanen

Naps, Learning and REM : The Frontal Cortex - 0 views

  • Taking a nap without REM sleep also led to slightly better results. But a nap that included REM sleep resulted in nearly a 40 percent improvement over the pre-nap performance.
  • The study, published June 8 in The Proceedings of the National Academy of Sciences, found that those who had REM sleep took longer naps than those who napped without REM, but there was no correlation between total sleep time and improved performance. Only REM sleep helped.
  • Numerous studies have now demonstrated that REM sleep is an essential part of the learning process. Before you can know something, you have to dream about it.
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  • The breakthrough came in 1972, when psychologist Jonathan Winson came up with a simple theory: The rabbit brain exhibited the same pattern of activity when it was scared and when it was dreaming because it was dreaming about being scared. The theta rhythm of sleep was just the sound of the mind processing information, sorting through the day's experiences and looking for any new knowledge that might be important for future survival. They were learning while dreaming, solving problems in their sleep.
  • Wilson began his experiment by training rats to run through mazes. While a rat was running through one of these labyrinths, Wilson measured clusters of neurons in the hippocampus with multiple electrodes surgically implanted in its brain. As he'd hypothesized, Wilson found that each maze produced its own pattern of neural firing. To figure out how dreams relate to experience, Wilson recorded input from these same electrodes while the rats were sleeping. The results were astonishing. Of the 45 rat dreams recorded by Wilson, 20 contained an exact replica of the maze they had run earlier that day. The REM sleep was recapitulating experience, allowing the animals to consolidate memory and learn new things. Wilson's lab has since extended these results, demonstrating that "temporally structured replay" occurs in both the hippocampus and visual cortex.
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    Taking a nap without REM sleep also led to slightly better results. But a nap that included REM sleep resulted in nearly a 40 percent improvement over the pre-nap performance
Ruth Howard

BBC News - Brain scans 'can distinguish memories', say scientists - 0 views

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    Scientists say they have been able to tell which past event a person is recalling using a brain scan. The University College London researchers showed people film clips and were able to predict which ones they were subsequently thinking about.
Tero Toivanen

Your Brain at Work - YouTube - 0 views

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    This is Fantastic!
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    This is Fantastic! via Jesse Soininen
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