Skip to main content

Home/ Neuropsychology/ Group items tagged brains

Rss Feed Group items tagged

Tero Toivanen

» Brain Plasticity: How learning changes your brain   « Brain Fitness Revolut... - 0 views

  • A surprising consequence of neuroplasticity is that the brain activity associated with a given function can move to a different location as a consequence of normal experience, brain damage or recovery.
  • The brain compensates for damage by reorganizing and forming new connections between intact neurons. In order to reconnect, the neurons need to be stimulated through activity.
  • Research has shown that in fact the brain never stops changing through learning. Plasticity IS the capacity of the brain to change with learning. Changes associated with learning occur mostly at the level of the connections between neurons. New connections can form and the internal structure of the existing synapses can change.
  • ...6 more annotations...
  • It looks like learning a second language is possible through functional changes in the brain: the left inferior parietal cortex is larger in bilingual brains than in monolingual brains.
  • For instance, London taxi drivers have a larger hippocampus (in the posterior region) than London bus drivers (Maguire, Woollett, & Spiers, 2006)…. Why is that? It is because this region of the hippocampus is specialized in acquiring and using complex spatial information in order to navigate efficiently. Taxi drivers have to navigate around London whereas bus drivers follow a limited set of routes.
  • Did you know that when you become an expert in a specific domain, the areas in your brain that deal with this type of skill will grow?
  • Plastic changes also occur in musicians brains compared to non-musicians.
  • They found that gray matter (cortex) volume was highest in professional musicians, intermediate in amateur musicians, and lowest in non-musicians in several brain areas involved in playing music: motor regions, anterior superior parietal areas and inferior temporal areas.
  • Medical students’ brains showed learning-induced changes in regions of the parietal cortex as well as in the posterior hippocampus. These regions of the brains are known to be involved in memory retrieval and learning.
  •  
    A surprising consequence of neuroplasticity is that the brain activity associated with a given function can move to a different location as a consequence of normal experience, brain damage or recovery.
Tero Toivanen

Use It or Lose It: The Principles of Brain Plasticity - 3 views

  • You probably haven't realizd it, but as you acquire an ability – for example, the ability to read – you have actually created a system in the brain that does not exist, that's not in place, in the non-reader. It [the ability; the brain system that controls the ability] actually evolves in you as it has been acquired through experience or learning.
  • "There are some very useful exercises at www.BrainHQ.com that are free, and using them can give a person a better understanding of how exercising your brain can drive it in a rejuvenating direction. Using exercises at BrainHQ, most people, of any age, can drive sharp improvements in brain speed and accuracy, and thereby rewire the brain so that it again represents information in detail," he says.
  • Children operating in the 10th to 20th percentile of academic performance are commonly able to improve their scores to the middle or average level with 20-30 hours of intensive computer-based training. "That's a big difference for the child," he says. "It carries most children who are near the bottom of the class, on the average, to be somewhere in the middle or above average in the class. And that gives struggling children a chance to really succeed and in many cases excel in school."
  • ...18 more annotations...
  • Careful controlled studies in seniors have also been reported in scientific journals. After 40 hours of computer-based training, the average improvement in cognitive performance across the board was 14 years. On average, if you were 70 years old when you underwent the training after 40 hours of brain training, your cognitive abilities operated like that of a 56-year old. Equally strong or even greater effects were seen in 40 to 50 year olds using the program. Individuals who worked on the BrainHQ exercises at home did just as well as those who completed training in a clinic or research center.
  • Ideally, it would be wise to invest at least 20 minutes a day. But no more than five to seven minutes is to be spent on a specific task. When you spend longer amounts of time on a task, the benefits weaken. According to Dr. Merzenich, the primary benefits occur in the first five or six minutes of the task.
  • Find ways to engage yourself in new learning
  • "When it matters to you, you are going to drive changes in your brain," he explains. "That's something always to keep in mind. If what you're doing seems senseless, meaningless, if it does not matter to you, then you're gaining less from it."
  • Get 15-30 minutes of physical exercise each day,
  • Spend about five minutes every day working on the refinement of a specific, small domain of your physical body.
  • You can typically improve yourself to the highest practical or possible level in anywhere between five to a dozen brief sessions of seven or eight minutes each. Again, having a sense of purpose is crucial.
  • Stay socially engaged.
  • Practice "mindfulness,"
  • Foods have an immense impact on your brain, and eating whole foods as described in my nutrition plan will best support your mental and physical health.
  • The medical literature is also showing that coconut oil can be of particular benefit for brain health, and anecdotal evidence suggests it could be very beneficial in the treatment of Alzheimer's disease.
  • Optimize your vitamin D levels
  • Take a high-quality animal-based omega-3 fat.
  • Avoid processed foods and sugars, especially fructose
  • Avoid grains
  • Avoid artificial sweeteners
  • Avoid soy
  • Men who ate tofu at least twice weekly had more cognitive impairment, compared with those who rarely or never ate the soybean curd, and their cognitive test results were about equivalent to what they would have been if they were five years older than their current age.
  •  
    "It was once thought that any brain function lost was irretrievable. Today, research into what's referred to as "brain plasticity" has proven that this is not the case. On the contrary, your brain continues to make new neurons throughout life in response to mental activity."
Tero Toivanen

Creativity and the Aging Brain | Psychology Today Blogs - 0 views

  • So instead of promoting retirement at age 65, perhaps we as a society should be promoting transition at age 65: transition into a creative field where our growing resource of individuals with aging brains can preserve their wisdom in culturally-valued works of art, music, or writing.
  • Numerous studies suggest that highly creative individuals also employ a broadened rather than focused state of attention. This state of widened attention allows the individual to have disparate bits of information in mind at the same time. Combining remote bits of information is the hallmark of the creative idea.
  • Other studies show that certain areas of the prefrontal cortex involved in self-conscious awareness and emotions are thinner in the aging brain. This may correlate with the diminished need to please and impress others, which is a notable characteristic of both aging individuals and creative luminaries.
  • ...1 more annotation...
  • Finally, intelligence studies indicate that older individuals have access to an increasing store of knowledge gained over a lifetime of learning and experience. Combining bits of knowledge into novel and original ideas is what the creative brain is all about.
  •  
    The aging brain resembles the creative brain in several ways. For instance, the aging brain is more distractible and somewhat more disinhibited than the younger brain (so is the creative brain). Aging brains score better on tests of crystallized IQ (and creative brains use crystallized knowledge to make novel and original associations).
Tero Toivanen

Left Brain and Right Brain | Boost Your IQ - 0 views

  • The left brain follows a completely different “way” and process of thinking from the right brain. The left brain sees things in an analytical, objective and logical manner. The right brain on the other hand is more symbol and metaphorically orientated.
  • In order to develop a particular brain, it is therefore necessary to focus on doing things which complement its attributes. For example, if I were to develop my left brain, i would embark on logical analysis and maths. If I were to exercise my right brain, i would indulge in art work.
  • do you see the dancer turning clockwise or anti-clockwise? If clockwise, then you use more of the right side of the brain and vice versa.
  •  
    do you see the dancer turning clockwise or anti-clockwise?
Tero Toivanen

Brain Foundation - Healthy Brain - 0 views

  •  
    The Healthy Brain Program, an initiative of the Brain Foundation, aims to assist Australians to keep their brains healthy into old age, through the provision of community education and research. The program aims to address issues such as: People are living longer, and the prevalence of degenerative brain disorders is increasing. There is little information available about how to keep the brain healthy compared to the wealth of information about a healthy body and heart. There is a need for a coordinated approach to education on key indicators and risk reduction strategies.
Tero Toivanen

Wired 14.02: Buddha on the Brain - 0 views

  • Davidson's research created a stir among brain scientists when his results suggested that, in the course of meditating for tens of thousands of hours, the monks had actually altered the structure and function of their brains.
  • Lutz asked Ricard to meditate on "unconditional loving-kindness and compassion." He immediately noticed powerful gamma activity - brain waves oscillating at roughly 40 cycles per second -�indicating intensely focused thought. Gamma waves are usually weak and difficult to see. Those emanating from Ricard were easily visible, even in the raw EEG output. Moreover, oscillations from various parts of the cortex were synchronized - a phenomenon that sometimes occurs in patients under anesthesia.
  • In the traditional view, the brain becomes frozen with the onset of adulthood, after which few new connections form. In the past 20 years, though, scientists have discovered that intensive training can make a difference. For instance, the portion of the brain that corresponds to a string musician's fingering hand grows larger than the part that governs the bow hand - even in musicians who start playing as adults. Davidson's work suggested this potential might extend to emotional centers
  • ...3 more annotations...
  • The researchers had never seen anything like it. Worried that something might be wrong with their equipment or methods, they brought in more monks, as well as a control group of college students inexperienced in meditation. The monks produced gamma waves that were 30 times as strong as the students'. In addition, larger areas of the meditators' brains were active, particularly in the left prefrontal cortex, the part of the brain responsible for positive emotions.
  • But Davidson saw something more. The monks had responded to the request to meditate on compassion by generating remarkable brain waves. Perhaps these signals indicated that the meditators had attained an intensely compassionate state of mind. If so, then maybe compassion could be exercised like a muscle; with the right training, people could bulk up their empathy. And if meditation could enhance the brain's ability to produce "attention and affective processes" - emotions, in the technical language of Davidson's study - it might also be used to modify maladaptive emotional responses like depression.
  • Davidson and his team published their findings in the Proceedings of the National Academy of Sciences in November 2004. The research made The Wall Street Journal, and Davidson instantly became a celebrity scientist.
  •  
    Davidson's research created a stir among brain scientists when his results suggested that, in the course of meditating for tens of thousands of hours, the monks had actually altered the structure and function of their brains
Tero Toivanen

Selective aphasia in a brain damaged bilingual patient : Neurophilosophy - 0 views

  • A unique case study published in the open access journal Behavioral and Brain Functions sheds some light on this matter. The study, by Raphiq Ibrahim, a neurologist at the University of Haifa, describes a bilingual Arabic-Hebrew speaker who incurred brain damage following a viral infection. Consequently, the patient experienced severe deficits in Hebrew but not in Arabic. The findings support the view that specific components of a first and second language are represented by different substrates in the brain.
  • A native Arabic speaker, he learned Hebrew at an early age (4th grade) and later used it competently both professionally and academically.
  • A CT scan showed that he had suffered a massive hemorrhage in the left temporal lobe, which was compressing the tissue on both sides of the central sulcus, the prominent gfissure which separates the frontal and parietal lobes.
  • ...4 more annotations...
  • A craniotomy was performed to relieve the pressure, and afterwards another scan showed moderate hemorrhage and herpes encephalitis in the left temporal lobe, and another hemorrhage beneath the outer membrane (the dura) lying over the right frontal lobe.
  • During his 2 month stay there, he developed epileptic seizures which originated in the left temporal lobe, and amnestic aphasia (an inability to name objects or to recognize their written or spoken names). 
  • After the rehabilitation period, a series of linguistic tests was administered to determine the extent of his speech deficits. M.H. exhibited deficits in both languages, but the most severe deficits were seen only in Hebrew. In this language he had a severe difficulty in recalling words and names, so that his speech was non-fluent and interrupted by frequent pauses. He had difficulty understanding others' spoken Hebrew, and also had great difficulty reading and writing Hebrew. In Arabic, his native language, all of these abilities were affected only mildy.
  • The results support a neurolinguistic model in which the brain of bilinguals contains a semantic system (which represents word meanings) which is common to both languages and which is connected to independent lexical systems (which encode the vocabulary of each language). The findings further suggest that the second language (in this case, Hebrew) is represented by an independent subsystem which does not represent the first language (Arabic) and is more succeptible to brain damage.
  •  
    A unique case study published in the open access journal Behavioral and Brain Functions sheds some light on this matter. The study, by Raphiq Ibrahim, a neurologist at the University of Haifa, describes a bilingual Arabic-Hebrew speaker who incurred brain damage following a viral infection. Consequently, the patient experienced severe deficits in Hebrew but not in Arabic. The findings support the view that specific components of a first and second language are represented by different substrates in the brain.
Tero Toivanen

AK's Rambling Thoughts: Nerve Cells and Glial Cells: Redefining the Foundation of Intel... - 0 views

  • Glia are generally divided into two broad classes, microglia and macroglia. Microglia are part of the immune system, specialized macrophages, and probably don't participate in information handling. Macroglia are present in both the peripheral and central nervous systems, in different types.
  • Traditionally, there were four types of glia in the CNS: astrocytes, oligodendrocytes, ependymal cells, and radial glia. Of these, the one type that's most important to the developing revolution in our ideas are those cells called astrocytes.2 It turns out that there are at least two types of cell (at least) subsumed under this name.24, 25, 31, 32 One, which retains the name of astrocyte, takes up neurotransmitters released by neurons (and glial cells), aids in osmoregulation,10 controls circulation in the brain,1, 31 and generally appears to provide support for the neurons and other types of glia.
  • Although both NG2-glia and astrocytes extend processes to nodes of Ranvier in white matter ([refs]) and synapses in grey matter, their geometric relationship to these neuronal elements is different. Thus, although astrocytes and NG2-glia bear a superficial resemblance, they are distinguished by their different process arborizations. This will reflect fundamental differences in the way these two glial cell populations interact with other elements in the neural network.
  • ...13 more annotations...
  • Both types of glia are closely integrated with the nervous system, receiving information from action potentials via synapses22 (which, only a few years ago were thought to be limited to neurons), and returning control of neuron activity through release of neurotransmitters and other modulators. Both, then, demonstrate the potential for considerable intelligent activity, contributing to the overall intelligence of the brain.
  • Astrocytes probably (IMO) are limited, or mostly so, to maintaining the supplies of energy and necessary metabolites. They receive action potentials,3, 6 which allows them to closely and quickly monitor general activity and increase circulation in response, even before the neurons and NG2-glia have reduced their supply of ATP.21 They appear to be linked in a network among themselves,2, 5 allowing them to communicate their needs without interfering with the higher-level calculations of the brain.
  • NG2-glia appear to have several functions, but one of the most exciting things about them is that they seem to be able to fire action potentials.33 Their cell membranes, like those of the dendrites of neurons, have all the necessary channels and receptors to perform real-time electrical calculations in the same way as neural dendrites. They have also demonstrated the ability to learn through long term potentiation.
  • Dividing NG2-glia also retain the ability to fire action potentials, as well as receiving synaptic inputs from neurons.23 Presumably, they continue to perform their full function, including retaining any elements of long term potentiation or depression contained in their synapses.
  • Oligodendrocytes are responsible for the insulation of the axons, wrapping around approximately 1 mm of each of up to 50 axons within their reach, and forming the myelin sheath.
  • Although the precise type of neuron formed by maturing cells hasn't been determined, the very fact that cells of this type can change into neurons is very important. We actually don't know whether the cells that do this maturation are the same as those that perform neuron-like activities, there appear to be two separate types of NG2-glia, spiking and non-spiking.26 It may very well be that the "spiking" type have actually differentiated, while the "non-spiking" type may be doing the maturing. Of course, very few differentiated cell types remain capable of division, as even the "spiking" type do.
  • What's important about both dendrites and NG2-glia isn't so much their ability to propagate action potentials, as that their entire cell membranes are capable of "intelligent" manipulation of the voltage across it.
  • While there are many ion channels involved in controlling the voltage across the cell membrane, the only type we really need to worry about for action potentials is voltage-gated sodium channels. These are channels that sometimes allow sodium ions to pass through the cell membrane, which they will do because the concentration of sodium ions outside the cell is very much higher than inside. When and how much they open depends, among other things, on the voltage across the membrane.
  • A normal neuron will have a voltage of around -60 to -80mV (millivolts), in a direction that tends to push the sodium ions (which are positive) into the cell (the same direction as the concentration is pushing). When the voltage falls to around -55mV, the primary type of gate will open for a millisecond or so, after which it will close and rest for several milliseconds. It won't be able to open again until the voltage is somewhere between -55 and around -10mV. Meanwhile, the sodium current has caused the voltage to swing past zero to around +20mV.
  • When one part of the cell membrane is "depolarized" in this fashion, the voltage near it is also depressed. Thus, if the voltage is at zero at one point, it might be at -20mV 10 microns (μm) away, and -40mV 20μm away, and -60mV 30μm, and so on. Notice that somewhere between 20μm and 30μm, it has passed the threshold for the ion channels, which means that they are open, allowing a current that drives the voltage further down. This will produce a wave of voltage drop along the membrane, which is what the action potential is.
  • After the action potential has passed, and the gates have closed (see above), the voltage is recovered by diffusion of ions towards and away from the membrane, the opening of other gates (primarily potassium), and a set of pumps that push the ions back to their resting state. These pumps are mostly powered by the sodium gradient, except for the sodium/potassium pump that maintains it, which is powered by ATP.
  • the vast majority of calculation that goes into human intelligence takes place at the level of the network of dendrites and NG2-glia, with the whole system of axons, dendrites, and action potentials only carrying a tiny subset of the total information over long distances. This is especially important considering that the human brain has a much higher proportion of glial matter than our relatives.
  • This, in turn, suggests that our overall approach to understanding the brain has been far too axon centric, there needs to be a shift to a more membrane-centric approach to understanding how the brain creates intelligence.
  •  
    Our traditional idea of how the brain works is based on the neuron: it fires action potentials, which travel along the axon and, when the reach the synapses, the receiving neuron performs a calculation that results in the decision when (or whether) to fire its own action potential. Thus, the brain, from a thinking point of view, is viewed as a network of neurons each performing its own calculation. This view, which I'm going to call the axon-centric view, is simplistic in many ways, and two recent papers add to it, pointing up the ways in which the glial cells of the brain participate in ongoing calculation as well as performing their more traditional support functions.
Tero Toivanen

First Evidence That Musical Training Affects Brain Development In Young Children - 0 views

  • The findings, published today (20 September 2006) in the online edition of the journal Brain [1], show that not only do the brains of musically-trained children respond to music in a different way to those of the untrained children, but also that the training improves their memory as well. After one year the musically trained children performed better in a memory test that is correlated with general intelligence skills such as literacy, verbal memory, visiospatial processing, mathematics and IQ.
  • Researchers have found the first evidence that young children who take music lessons show different brain development and improved memory over the course of a year compared to children who do not receive musical training.
  • While previous studies have shown that older children given music lessons had greater improvements in IQ scores than children given drama lessons, this is the first study to identify these effects in brain-based measurements in young children.
  • ...6 more annotations...
  • The researchers chose children being trained by the Suzuki method for several reasons: it ensured the children were all trained in the same way, were not selected for training according to their initial musical talent and had similar support from their families. In addition, because there was no early training in reading music, the Suzuki method provided the researchers with a good model of how training in auditory, sensory and motor activities induces changes in the cortex of the brain.
  • Analysis of the MEG responses showed that across all children, larger responses were seen to the violin tones than to the white noise, indicating that more cortical resources were put to processing meaningful sounds. In addition, the time that it took for the brain to respond to the sounds (the latency of certain MEG components) decreased over the year. This means that as children matured, the electrical conduction between neurons in their brains worked faster.
  • Of most interest, the Suzuki children showed a greater change over the year in response to violin tones in an MEG component (N250m) related to attention and sound discrimination than did the children not taking music lessons.
  • Analysis of the music tasks showed greater improvement over the year in melody, harmony and rhythm processing in the children studying music compared to those not studying music. General memory capacity also improved more in the children studying music than in those not studying music.
  • The finding of very rapid maturation of the N250m component to violin sounds in children taking music lessons fits with their large improvement on the memory test. It suggests that musical training is having an effect on how the brain gets wired for general cognitive functioning related to memory and attention.
  • It is clear that music is good for children's cognitive development and that music should be part of the pre-school and primary school curriculum.
  •  
    Researchers have found the first evidence that young children who take music lessons show different brain development and improved memory over the course of a year compared to children who do not receive musical training.
Tero Toivanen

Adult Learning - Neuroscience - How to Train the Aging Brain - NYTimes.com - 1 views

  • One explanation for how this occurs comes from Deborah M. Burke, a professor of psychology at Pomona College in California. Dr. Burke has done research on “tots,” those tip-of-the-tongue times when you know something but can’t quite call it to mind. Dr. Burke’s research shows that such incidents increase in part because neural connections, which receive, process and transmit information, can weaken with disuse or age.
  • But she also finds that if you are primed with sounds that are close to those you’re trying to remember — say someone talks about cherry pits as you try to recall Brad Pitt’s name — suddenly the lost name will pop into mind. The similarity in sounds can jump-start a limp brain connection. (It also sometimes works to silently run through the alphabet until landing on the first letter of the wayward word.)
  • Recently, researchers have found even more positive news. The brain, as it traverses middle age, gets better at recognizing the central idea, the big picture. If kept in good shape, the brain can continue to build pathways that help its owner recognize patterns and, as a consequence, see significance and even solutions much faster than a young person can.
  • ...5 more annotations...
  • The trick is finding ways to keep brain connections in good condition and to grow more of them.
  • Educators say that, for adults, one way to nudge neurons in the right direction is to challenge the very assumptions they have worked so hard to accumulate while young. With a brain already full of well-connected pathways, adult learners should “jiggle their synapses a bit” by confronting thoughts that are contrary to their own, says Dr. Taylor, who is 66.
  • Teaching new facts should not be the focus of adult education, she says. Instead, continued brain development and a richer form of learning may require that you “bump up against people and ideas” that are different. In a history class, that might mean reading multiple viewpoints, and then prying open brain networks by reflecting on how what was learned has changed your view of the world.
  • Such stretching is exactly what scientists say best keeps a brain in tune: get out of the comfort zone to push and nourish your brain. Do anything from learning a foreign language to taking a different route to work.
  • “As adults we have these well-trodden paths in our synapses,” Dr. Taylor says. “We have to crack the cognitive egg and scramble it up. And if you learn something this way, when you think of it again you’ll have an overlay of complexity you didn’t have before — and help your brain keep developing as well.”
  •  
    Dr. Burke has done research on "tots," those tip-of-the-tongue times when you know something but can't quite call it to mind. Dr. Burke's research shows that such incidents increase in part because neural connections, which receive, process and transmit information, can weaken with disuse or age.
Tero Toivanen

Wires Inserted Into Human Brain Reveal Speech Surprise | Wired Science | Wired.com - 1 views

  • in’s team benefited from a brain-reading technology called intra-cranial electrophysiology, or ICE, in which electrodes are positioned inside the brain itself. It’s a medical rather than a research tool, used to precisely measure electrical activity in the brains of epileptics who don’t respond to treatment.
  • This tested only one type of verbal cognition, cautioned Sahin, and the focus was unavoidably narrow, but it was enough to show that Broca’s area is involved not only in translating speech, but receiving it. That role was considered specific to part of the brain called Wernicke’s area. More broadly, the findings may represent a general rule for Broca’s area, and perhaps other brain regions: Each part plays multiple roles, rather than performing a single task.
  •  
    This tested only one type of verbal cognition, cautioned Sahin, and the focus was unavoidably narrow, but it was enough to show that Broca's area is involved not only in translating speech, but receiving it. That role was considered specific to part of the brain called Wernicke's area. More broadly, the findings may represent a general rule for Broca's area, and perhaps other brain regions: Each part plays multiple roles, rather than performing a single task.
Tero Toivanen

Sign language study shows multiple brain regions wired for language - 1 views

  • A new study from the University of Rochester finds that there is no single advanced area of the human brain that gives it language capabilities above and beyond those of any other animal species.
  • Instead, humans rely on several regions of the brain, each designed to accomplish different primitive tasks, in order to make sense of a sentence.
  • "We're using and adapting the machinery we already have in our brains," said study coauthor Aaron Newman. "Obviously we're doing something different [from other animals], because we're able to learn language unlike any other species. But it's not because some little black box evolved specially in our brain that does only language, and nothing else."
  • ...4 more annotations...
  • The team of brain and cognitive scientists
  • published their findings in the latest edition of the journal Proceedings of the National Academies of Sciences.
  • The study found that there are, in fact, distinct regions of the brain that are used to process the two types of sentences: those in which word order determined the relationships between the sentence elements, and those in which inflection was providing the information.
  • In fact, Newman said, in trying to understand different types of grammar, humans draw on regions of the brain that are designed to accomplish primitive tasks that relate to the type of sentence they are trying to interpret. For instance, a word order sentence draws on parts of the frontal cortex that give humans the ability to put information into sequences, while an inflectional sentence draws on parts of the temporal lobe that specialize in dividing information into its constituent parts, the study demonstrated.
  •  
    A new study from the University of Rochester finds that there is no single advanced area of the human brain that gives it language capabilities above and beyond those of any other animal species.
Tero Toivanen

New Light On Nature Of Broca's Area: Rare Procedure Documents How Human Brain Computes ... - 0 views

  • The study – which provides a picture of language processing in the brain with unprecedented clarity – will be published in the October 16 issue of the journal Science.
  • "Two central mysteries of human brain function are addressed in this study: one, the way in which higher cognitive processes such as language are implemented in the brain and, two, the nature of what is perhaps the best-known region of the cerebral cortex, called Broca's area," said first author Ned T. Sahin, PhD, post-doctoral fellow in the UCSD Department of Radiology and Harvard University Department of Psychology.
  • The study demonstrates that a small piece of the brain can compute three different things at different times – within a quarter of a second – and shows that Broca's area doesn't just do one thing when processing language.
  • ...2 more annotations...
  • The procedure, called Intra-Cranial Electrophysiology (ICE), allowed the researchers to resolve brain activity related to language with spatial accuracy down to the millimeter and temporal accuracy down to the millisecond.
  • "We showed that distinct linguistic processes are computed within small regions of Broca's area, separated in time and partially overlapping in space," said Sahin. Specifically, the researchers found patterns of neuronal activity indicating lexical, grammatical and articulatory computations at roughly 200, 320 and 450 milliseconds after the target word was presented. These patterns were identical across nouns and verbs and consistent across patients.
  •  
    "Two central mysteries of human brain function are addressed in this study: one, the way in which higher cognitive processes such as language are implemented in the brain and, two, the nature of what is perhaps the best-known region of the cerebral cortex, called Broca's area," said first author Ned T. Sahin, PhD, post-doctoral fellow in the UCSD Department of Radiology and Harvard University Department of Psychology.
Tero Toivanen

NIMH · Our brains are made of the same stuff, despite DNA differences - 0 views

  • “Having at our fingertips detailed information about when and where specific gene products are expressed in the brain brings new hope for understanding how this process can go awry in schizophrenia, autism and other brain disorders,” said NIMH Director Thomas R. Insel, M.D.
  • Among key findings in the prefrontal cortex:Individual genetic variations are profoundly linked to expression patterns. The most similarity across individuals is detected early in development and again as we approach the end of life.Different types of related genes are expressed during prenatal development, infancy, and childhood, so that each of these stages shows a relatively distinct transcriptional identity. Three-fourths of genes reverse their direction of expression after birth, with most switching from on to off.Expression of genes involved in cell division declines prenatally and in infancy, while expression of genes important for making synapses, or connections between brain cells, increases. In contrast, genes required for neuronal projections decline after birth – likely as unused connections are pruned.By the time we reach our 50s, overall gene expression begins to increase, mirroring the sharp reversal of fetal expression changes that occur in infancy.Genetic variation in the genome as a whole showed no effect on variation in the transcriptome as a whole, despite how genetically distant individuals might be. Hence, human cortexes have a consistent molecular architecture, despite our diversity.
  • Among key findings:Over 90 percent of the genes expressed in the brain are differentially regulated across brain regions and/or over developmental time periods. There are also widespread differences across region and time periods in the combination of a gene’s exons that are expressed.Timing and location are far more influential in regulating gene expression than gender, ethnicity or individual variation.Among 29 modules of co-expressed genes identified, each had distinct expression patterns and represented different biological processes. Genetic variation in some of the most well-connected genes in these modules, called hub genes, has previously been linked to mental disorders, including schizophrenia and depression.Telltale similarities in expression profiles with genes previously implicated in schizophrenia and autism are providing leads to discovery of other genes potentially involved in those disorders.Sex differences in the risk for certain mental disorders may be traceable to transcriptional mechanisms. More than three-fourths of 159 genes expressed differentially between the sexes were male-biased, most prenatally. Some genes found to have such sex-biased expression had previously been associated with disorders that affect males more than females, such as schizophrenia, Williams syndrome, and autism.
  • ...2 more annotations...
  • Our brains are all made of the same stuff. Despite individual and ethnic genetic diversity, our prefrontal cortex shows a consistent molecular architecture.
  • Males show more sex-biased gene expression. More genes differentially expressed (DEX) between the sexes were found in males than females, especially prenatally. Some genes found to have such sex-biased expression had previously been associated with disorders that affect males more than females, such as schizophrenia, Williams syndrome, and autism.
  •  
    Our brains are all made of the same stuff. Despite individual and ethnic genetic diversity, our prefrontal cortex shows a consistent molecular architecture. 
Tero Toivanen

» Working Memory Training can Influence Brain Biochemistry   « Brain Fitness ... - 0 views

  • The major finding was that increased working memory capacity following training was associated with changes in brain biochemistry. Specifically, the researchers found changes in the density and binding potential of cortical D1 dopamine receptors in brain regions that are activated during working memory tasks.
  •  
    The major finding was that increased working memory capacity following training was associated with changes in brain biochemistry. Specifically, the researchers found changes in the density and binding potential of cortical D1 dopamine receptors in brain regions that are activated during working memory tasks.
Tero Toivanen

Brain Stimulant: Brain Chip to Restore Functioning from Damage - 1 views

  • The ReNaChip project is developing electronic biomimetic technology that could serve to replace damaged or missing brain tissue. This is basically neuromorphic engineering that seeks to mimic how neurons function. In the future this may be useful for people who have had injuries due to stroke or other illnesses.
  • The objective of this project is to develop a full biohybrid rehabilitation and substitution methodology; replacing the aged cerebellar brain circuit with a biomimetic chip bidirectionally interfaced to the inputs and outputs of the system. Information processing will interface with the cerebellum to actuate a normal, real-time functional behavioural recovery, providing a proof-of-concept test for the functional rehabilitation of more complex neuronal systems.
  • A sophisticated exocortex could potentially allow a two way communication between the external apparatus and the mind. The contraption could essentially scale up the amount of neurons in your brain by an artificial means. Most likely it would be used to improved the disabled first, with other applications being more speculative possibilities.
  •  
    The ReNaChip project is developing electronic biomimetic technology that could serve to replace damaged or missing brain tissue. This is basically neuromorphic engineering that seeks to mimic how neurons function. In the future this may be useful for people who have had injuries due to stroke or other illnesses.
David McGavock

The Top 10 Challenges for Brain Science in 2013 - Forbes - 0 views

  • 1. Figure out what fMRI can truly tell us about our brains. 
  • There’s little question fMRI is valuable, but too many disparate forces are out there spinning brain scans in too many ways. Perhaps one solution, or start of a solution, is a summit hosted by a credible, well-respected institute or organization to gather the best of the best minds in the field to establish a game plan moving forward.
  • 2. Determine what role, if any, neuroscience should play in the courtroom.
  • ...12 more annotations...
  • . Continue crafting a constructive consilience between disciplines.
  • Neuroscience, behavioral science, evolutionary biology, economics, engineering, and even the humanities have all come to the proverbial table in the last few years
  • Produce more applicable knowledge and less curious meanderings.
  • 7. Join forces with more public health sources to engender broader awareness of critical issues. 
  • Try to fight the urge to spin off more headline pablum like “Brain Porn.”
  • How about we spend more time trying to solve the problems and less time concocting clever catch phrases?
  • Shine the light on how far the forces of marketing have exploited brain science advances (this is a genuine public service).
  • I am an unwavering advocate of making sure people understand how the forces of marketing are using the field to sell more products.
  • Again, what is truly “solid applicable knowledge” is frequently debatable (see #1 above), but every year the field–and by that I mean the interdisciplinary field (#3)–has more to offer the public.
  • 8. Put the brakes on “building a brain” — we already have plenty of them.
  • in my opinion we have enough to do with respect to figuring our how our organic brain works without spending massive resources on trying to recreate one.
  • 9. Turn the corner from “what’s wrong with our brains” to “what we can really do about it.” 
Tero Toivanen

Growing evidence of the brain's plasticity could benefit stroke victims or those suffer... - 0 views

  • With the right training, scientists now know the brain can reshape itself to work around dead and damaged areas, often with dramatic benefits.
  • Therapies that exploit the brain's power to adapt have helped people overcome damage caused by strokes, depression, anxiety and learning disabilities, and may one day replace drugs for some of these conditions.
  • Children with language difficulties have been shown to make significant progress using computer training tools that are the equivalent of cerebral cross-training.
  • ...2 more annotations...
  • Neuroplasticity does not see the different regions of the brain as completely versatile and certainly not interchangeable. But it recognises that if part of the brain is damaged, it can be possible to train other areas to take on, at least to some extent, the job of the lost brain matter.
  • Doidge says he is not anti-medication, but wonders if therapies that tap into neuro-plasticity will soon replace drug treatments for certain conditions. "We can change our brains by sensing, imagining and acting in the world. It's economical and mostly low-tech, and I'm very, very hopeful"
  •  
    With the right training, scientists now know the brain can reshape itself to work around dead and damaged areas, often with dramatic benefits.
Tero Toivanen

Music and Intelligence | Boost Your IQ - 0 views

  • Studies indicate that early exposure to musical training helps a child’s brain reach its potential by generating neural connections utilized in abstract reasoning.
  • The reasoning skills required for a test in spatial reasoning are the same ones children use when they listen to music. Children use these reasoning skills to order the notes in their brain to form the melodies. Also, some concepts of math must be understood in order to understand music. Experts speculate that listening to music exercises the same parts of the brain that handle mathematics, logic, and higher level reasoning.
  • In 1997 a study involving three groups of preschoolers was conducted to determine the effect of music versus computer training on early childhood development.
  • ...9 more annotations...
  • The group that received the piano/keyboard training scored 34% higher on tests measuring spatial-temporal ability than either of the other two groups. These results suggest that music enhances certain higher brain functions, particularly abstract reasoning skills, required in math and science.
  • The use of music in training four and five year old children yielded the highest improvement in the ability to name body parts.
  • Although the three experimental groups displayed an increase in their ability to name body parts the music group exhibited the highest degree of improvement.
  • First grade students received extensive Kodaly training for seven months.
  • At the end of seven months the experimental group had higher reading scores than the control group, which did not receive any special treatment. Not only did the seven month instruction increase reading scores, but continued musical training proved to be beneficial. The experimental group continued to show higher reading scores with continued training.
  • Students who were involved in arts education achieved higher SAT scores. The longer students were involved in arts education, the higher the increase in SAT scores. This study also correlated arts education with higher scores in standardized tests, reading, English, history, citizenship, and geography.
  • The results indicated that students with a relatively lower socioeconomic status, that were exposed to arts education, had an advantage over those students without any arts education which was proportionally equal to the students with a relatively higher socioeconomic status and exposure to arts education.
  • Music exposure affects older students as well. Three groups of college students were exposed to either Mozart’s Sonata for Two Pianos, K448, a relaxation tape, or silence. The group exposed to the Mozart piece was the only group to achieve an increase on the spatial IQ test. Further studies revealed that neither dance music nor taped short stories produced an increase in spatial IQ similar to the Mozart piece. The increase in spatial IQ appears to be related to some unique aspects of the Mozart piece rather than music in general.
  • Music may not only be related to intelligence by its stimulation of the brain, but it may also increase intelligence by the type of attitudes, interests, and discipline it fosters in children.
  •  
    Studies indicate that early exposure to musical training helps a child's brain reach its potential by generating neural connections utilized in abstract reasoning.
Tero Toivanen

How Does the Brain Recover After Stroke? | Brain Blogger - 1 views

  •  
    "A recent study published in Brain demonstrates the ingenious ability of the central nervous system to repair itself after brain injury."
1 - 20 of 136 Next › Last »
Showing 20 items per page