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Ali Ghafour of Viafoura talks with the Globe and Mail experts about how their startup can land a big opportunity on terms it feels comfortable with, or whether they should walk away.

Ethical Ocean is a MaRS Client who specializes in selling socially responsible products only made a strategic pivot in their model. Nathan Monk, a senior associate with MaRS Discovery District in Toronto and an adviser in the Web and mobile technology startup community, says it's important to constantly review and test business models or hypotheses.

The three founders of startup tech company Nevex Virtual Technologies Inc. who have been working together for about 20 years and have successfully developed, grown and sold several businesses between them, netting stakeholders more than $300-million in value.

Cynthia Goh, guest columnist, Globe and Mail states that the path of commercializing research is a "painfully gradual and meandering." Cynthia Goh, created "a lecture series to train scientist-entrepreneurs that later evolved into Entrepreneurship101 at Toronto's MaRS Discovery District - possibly the largest training program in Canada with about 1,500 registered participants each year. "

A place for Toronto's tech startups, entrepreneurs, and talk.

YouNoodle is a place to discover and support the hottest early-stage companies and university innovation.

Founders and funders both must understand valuation for pre-revenue and startup entrepreneurial ventures. * Which key factors should angel investors consider to determine value? * How can entrepreneurs present their companies more effectively? This Collection from Kauffman Foundation eVenturing provides insights to reduce the natural contentiousness of negotiating valuation.

While governance and fiduciary matters command a bigger share of their time and attention, the hiring of CEOs is among the most important, value-added responsibilities of Boards of Directors. It is also one exercised ever more frequently, with statistics showing that two-thirds of all venture-backed startup companies replace their founding CEOs and of these replacements, two out of every five fail in the first 18 months.

InDanio, a drug-discovery company based in Toronto's MaRS Discovery District, focuses on nuclear receptors, a class of proteins that are related to some of the most \ndevastating and prevalent diseases on the planet, including immune disorders, obesity, diabetes and most cancers.

InDanio, a drug-discovery company based in Toronto's MaRS Discovery District, focuses on nuclear receptors, a class of proteins that are related to some of the most devastating and prevalent diseases on the planet, including immune disorders, obesity, diabetes and most cancers. devastating and prevalent diseases on the planet, including immune disorders, obesity, diabetes and most cancers.

This online chapter of Canadian Business provides established and up-and-coming Canadian entrepreneurs with current and newsworthy information. Focus is placed on finance, management, sales and marketing, technology, and exporting. In addition: * A 'Personal Development' section provides information on best practices, stress management, and more. * A 'How To' section provides information on dealing with various business problems. o From legal matters to corporate motivation. * A 'Startup Guide' section provides the reader with a report on 2008's best niches for start-ups. * Access to PROFIT Magazine is also given.

Advice for the Starbucks CEO ... or anyone in a start-up. If Starbucks can learn, so can you.

Did you InGame during the SuperBowl this weekend? InGamer fuses the three dominant screens in our lives: television, computer and mobile.

How and where you should consider advertising if you're on a lean start-up budget. From OnStartups.com guest blogger, author and entrepreneur, Rob Wailing.

The Star features MaRS client, WeblishPal, an online tutoring software that pairs English-speaking tutors with foreign-language students to find each other, set up tutoring sessions and rate the teacher.

gShift Labs, a MaRS client, closed $1.1 million funding round. gSift Labs was named startup of the year in 2010 by the Canadian Innovation Exchanged. gShift Labs is a MaRS Client.

The Next 36 is Canada's Entrepreneurial Initiative. According to Mark Zimmerman, MaRS' Senior ICE Advisor, "the Next 36 is a student spin off of the provincially and corporately backed MaRS Centre for Innovation, if you will, which backs over 1200 startups, 140 of which are mobile."