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Sean Nash

Health Effects from Swimming Training in Chlorinated Pools and the Corresponding Metabo... - 4 views

www.ncbi.nlm.nih.gov/...PMC4351252

swimming chlorine mice-experimenting HSR2023 blood liver pools

shared by Sean Nash on 13 Jul 23 - No Cached
  • Numerous epidemiological publications have associated the chlorination of pools with dysfunctions of the respiratory system and with some other diseases
  • Therefore, the health effects from swimming in chlorinated pools and the corresponding stress reactions in organisms are unclear. In this study, we show that although the growth and behaviors of experimental rats were not affected, their health, training effects and metabolic profiles were significantly affected by a 12-week swimming training program in chlorinated water identical to that of public pools.
    • katherine-medina
      katherine-medina on 13 Jul 23
       
      This may prove to be a concerning fact that myself and others on the swim team swim rather consistently.
  • The epidemiological evidence for adverse health effects from swimming in chlorinated water primarily originate from studies concerning respiratory function and asthma, althoughVillanueva et al. reported a significant increased risk of bladder cancer for swimmers compared with nonswimmers [5].
    • katherine-medina
      katherine-medina on 13 Jul 23
       
      Kinda scary to think about the fact that swimming could be hurting my lungs.
    • Sean Nash
      Sean Nash on 13 Jul 23
       
      OK... this is all a very rare and interesting topic to me. I've never considered it. Of course, in thinking a bout this as a HS research topic, the fact that it centers around humans... is a feasibility issue. However, what sort of invertebrate models could we use in place? Would we be able to detect DBPs?
  • ...24 more annotations...
  • Interestingly, the eyes and skin are the organs that are more directly affected than the lungs by the irritants in chlorinated water; instead of chlorination, training intensity, training frequency and choking on water may be the primary factors for lung damage induced by swimming.
  • he water for the EG was purified using a water purifier and then disinfected using calcium hypochlorite, similar to public swimming pools, whereas the water for the CG was only purified, not chlorinate
  • Therefore, the health effects from swimming in chlorinated pools and the corresponding stress reactions occurring in our bodies are unclear
  • In fact, similar symptoms, red and swollen eyes, dried skin and nasal mucosal congestion, always appear after humans swim in a chlorinated pool; however, the long-term (12 weeks) and high-frequency (5 days a week) of the experimental swimming training caused even worse symptoms in these experimental rats.
  • however, some unusual appearance changes appeared in the EG rats.
    • katherine-medina
      katherine-medina on 13 Jul 23
       
      EG rats had the exposure of a public level of chlorine.
  • First, the skin around their eyes became increasingly red with the development of the experiment, and in the ending period of the experiment, bloodstains could be observed in the rims of most rats’ eyes.
    • katherine-medina
      katherine-medina on 13 Jul 23
       
      Wow.
  • Third, their fur became increasingly dry and lackluster, and significant signs of hair loss were observed during the last month.
    • katherine-medina
      katherine-medina on 13 Jul 23
       
      This doesn't sound good.
  • These results indicated that the fur, respiratory tracts and eyes of the EG rats were severely affected by chlorinated water, although their growth was essentially unaffected. According to our observations, the daily behaviors and sizes of the EG rats were normal, and their final body weights were even slightly heavier than those weights of the control group. Nevertheless, dried and lackluster fur, hair removal, bloody noses and eyes did occur in the EG rats and not to the CG rats.
  • A meta-analysis performed by Goodman et al. demonstrated that the association between asthma and swimming could only be confirmed among competitive swimmers and could not be confirmed among non-competitive swimmers
    • katherine-medina
      katherine-medina on 13 Jul 23
       
      SO competitive swimmers are the ones with an association of asthma and pool water.
  • Additionally, an interesting phenomenon was observed by comparing the development of the bloody noses and bloody eyes. The bloody noses commonly appeared in the third and in the fourth week; however, approximately two weeks later, this symptom gradually disappeared. The significantly bloody eyes commonly appeared in the ending period of the experiment; however, this problem was becoming worse during the study, and no signs of improvement appeared. The bloody noses appeared first, suggesting that respiratory tracts may be more vulnerable to the irritants from the chlorinated water than eyes; the gradually disappearing symptom suggests that respiratory tracts may have some adaptability to chlorinated water possibly because of the protection from nasal mucous. In contrast, without the mucosal protection, the bloody eyes were becoming increasingly significant during the entire experiment, although this symptom appeared later than the bloody noses.
  • Hippurate is an inhibitor of glucose utilization in the muscle and in the kidneys, an inhibitor of glucose utilization in the kidneys and in the liver, a modulator of fatty acid metabolism, and a stimulator of ammoniagenesis
  • Three rats from the EG were found liver damage, indicating that the positive rate reached 18 percen
  • or instance, Tumasonis et al. reported that a significantly increased incidence of hepatic neoplastic nodules in female rats and a significantly increased incidence of hepatic adenofibrosis in both male and female rats were induced by the chronic ingestion of chloroform [15].
  • Representative hematoxylin and eosin staining (H&E, 400×) of liver sections.
    • katherine-medina
      katherine-medina on 13 Jul 23
       
      The liver literally changed between the two groups.
  • . We suppose that the primary differences between the competitive swimmers and non-competitive swimmers are training intensity and frequency, not the pool water.
    • katherine-medina
      katherine-medina on 13 Jul 23
       
      An interesting theory, but I wonder if it has been proved.
  • The first three principal components (PCs) explain 57.3% of the total variance of the raw data and are sufficient to present the differences between the EG and the CG
  • In Fig. 3, we can see that the majority of the differences between the EG and the CG are explained by PC 1 and PC 3.
  • which suggests that the 12-week swimming training in chlorinated water induced a significant change in the metabolic profiles of the experimental group rats.
  • As an antioxidant, taurine can directly scavenge hypochlorous acid (HClO) and prevents changes in membrane permeability due to oxidative impairment
  • The duration period from the entry into water until the rats reached exhaustion was significantly shorter for the EG rats compared with the CG rats (29.74±11.50 vs. 39.15±9.85 minutes, p<0.05)
    • katherine-medina
      katherine-medina on 13 Jul 23
       
      Rats in chlorine swam ten minutes less on average.
  • Chlorine is a necessary element for our bodies, and nontoxic.
    • katherine-medina
      katherine-medina on 13 Jul 23
       
      I did not know that.
  • In summary, the 12-week swimming training in chlorinated pool water did induce some disease symptoms, an impairment of training effects and a significant change in the metabolic profiles, although the growth and behaviors of the experimental animals were not affected
  • Thus, the eyes and skin might be the organs that require greater attention for permanent damage.
  • Symptoms found in the liver and lung sections indicate that the liver is most likely the most possible target organ of DBPs, and training intensity, training frequency and water choking may be the primary factors for lung damage induced by swimming, instead of chlorination. The result of the swimming capacity test showed that training effects were significant affected by chlorinated water through perturbing the TCA cycle and oxidative phosphorylation.
  • katherine-medina on 13 Jul 23
     
    A really cool article about how chlorine can affect the bodies of mice. (An article I will never be able to forget about due to it being similar to my situation.)
  • Sean Nash on 13 Jul 23
     
    A really cool article about how chlorine can affect the bodies of mice. (An article I will never be able to forget about due to it being similar to my situation.)
katherine-medina

Sci-Hub | A droplet-based electricity generator with high instantaneous power density. ... - 0 views

sci-hub.se/...s41586-020-1985-6

water-power droplets electricity HSR-2023

shared by katherine-medina on 22 Aug 23 - No Cached
    • katherine-medina
      katherine-medina on 22 Aug 23
       
      We find that when a falling water droplet spreads on the PTFE surface, it bridges the originally disconnected components (the PTFE/ITO and aluminum electrode) into a closed-loop, electrical system Interesting.
    • katherine-medina
      katherine-medina on 22 Aug 23
       
      Fig. 1 | Design of the DEG. a, Schematic diagram. b, Optical image showing four parallel DEG devices fabricated on a glass substrate. The volume of each droplet is 100.0 μl. c, As individual droplets continue to impinge on the asfabricated device, the amount of charge on the PTFE surface increases gradually and eventually reaches a stable value. d, One hundred commercial LEDs can be powered when one droplet, released from a height of 15.0 cm, is in contact with the device. e, Under the same experimental conditions (for example, the same droplet size and height of release), the output voltage measured from the DEG (in red, with the frequency of impinging droplets being
  • katherine-medina on 22 Aug 23
     
    Interesting to see a different method on creating power out of water. I kinda of want to look into the science of water.
katherine-medina

(34) Water, Cells, and Life | Dr. Gerald Pollack | TEDxNewYorkSalon - YouTube - 0 views

www.youtube.com/watch

water electricity Research-idea HSR-2023

shared by katherine-medina on 18 Aug 23 - No Cached
  • katherine-medina on 18 Aug 23
     
    Looking at the basics of how water works
katherine-medina

Antioxidants | Free Full-Text | Drought and UV Radiation Stress Tolerance in Rice Is Im... - 0 views

www.mdpi.com/917

oryza-sativa rice UVR-Stress sun UV

shared by katherine-medina on 12 Feb 24 - No Cached
  • . Plant Material, Growth Conditions, and Phenotypic EvaluationWe used the rice (Oryza sativa L.) seeds of the transgenic (OxF3H) and non-transgenic Nogdong cultivars provided by the Plant Molecular Breeding Laboratory, Kyungpook National University, Korea [41]. Rice seeds were sterilized with fungicides overnight and then washed with double distilled water three times. Next, the rice seeds were soaked in water for four days in an incubator in the dark condition at 32 °C, with the water changed after each 24 h as previously reported by [41]. After soaking and successful sprouting, rice seeds were transferred to autoclaved soil and kept in the dark again for three days. After growth, the three week rice seedlings were exposed to light and kept in a greenhouse for further experimentation.
    • katherine-medina
      katherine-medina on 12 Feb 24
       
      Found ya, this study waited til rice was 3 weeks old!!!
  • 3. Results
  • 2.7
  • ...2 more annotations...
  • 2.8.
  • 2.9. Chlorophyll
  • katherine-medina on 12 Feb 24
     
    "genin converts very rapidly into flavonoids in response to drought and UV-B radiation stress (see Figure 5). The close image of detection of kaempferol and quercetin is represented in Supplementary Figure S3. "
Sean Nash

Learning in Plants: Lessons from Mimosa pudica - 4 views

www.frontiersin.org/...full

Mimosa learning plants botany research SCI-I science student lab potential research idea biology HSR HSR-2023

shared by Sean Nash on 23 Jun 23 - No Cached
  • there is a lack of observational data on the behavior of plants
  • Observational research allows the researcher to establish baseline activity and response levels of the subject
  • Perhaps the first study of learning in plants was a habituation experiment reported by Pfeffer (1873) using the sensitive plant Mimosa. In this experiment, repeated mechanical stimulation of leaflets led to a decrease in sensitivity
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  • the question naturally arises as to whether Mimosa can discriminate between stimuli. This was answered in the affirmative by Holmes and Gruenberg (1965) whose experimental design included a drop of water and finger touch as stimuli
  • the results suggest that Mimosa can discriminate between stimuli
  • Thomas performed an experiment on classical conditioning in Mimosa that took advantage of the finding that, under field conditions, the leaflets of Mimosa slowly drop as dusk approaches and slowly rise at dawn (personal communication). In the experiment, the CS was turning on the light in the growth chamber and the US was touching selected leaflets. Thomas found that leaflets in the paired condition showed conditioning compared to a light only or alternating stimulation condition. This finding should be replicated with controls for pseudoconditioning.
  • Given the importance of the Gagliano et al. (2014) experiment and the failure to replicate some previous experimental results it is critical that the Gagliano et al. (2014) results be repeated by an independent laboratory.
  • In addition to Mimosa, habituation has been found in the carnivorous plant Drosera (sundew
  • Applewhite (1975) cites an experiment by Darwin reportedly showing habituation in the passion flower (Passiflora gracilis). During this experiment, when Darwin mechanically stimulated the passion flower tendrils, the tendrils no longer responded after 54 h of training.
  • Abramson et al. (2002) investigated the use of bioelectrical potentials as a method to explore plant behavior.
  • In an interesting article, Karpinski and Szechynska-Hebda (2010) discuss the intellect of plants from memory to intelligence. By studying recall, the researcher investigates a host of independent variables and that are solidly anchored to a set of dependent variables. This study focused on recall at the cellular level rather than as an externally observable behavior. The discussion of plant learning at various levels, from cellular to organismal and from different scientific fields is exactly what is advocated for in this article
  • There is also interest from behavioral scientists seeking to determine whether the similarities and differences in learning found among invertebrates and vertebrates could also be found in plants (Warden et al., 1940; Applewhite, 1975; Abramson et al., 2002; Guiguet, 2013).
  • The majority of early plant studies used the Sensitive plant (M. pudica). Mimosa has much to recommend it for learning studies. They are easy to maintain, much is known about its natural history, and they have a visible leaf closure response to external stimuli. However, there are drawbacks in the use of Mimosa, for example, it takes about 15 min for a leaf to recover (Holmes and Gruenberg, 1965) and not much is known about its genome in contrast to model species such as Arabidopsis thaliana whose entire genome is known.
  • In the following section we will focus on methods to develop studies utilizing habituation, sensitization, and classical conditioning techniques. Instrumental and operant conditioning will not be covered because at this time there are no Mimosa studies in these areas; although one can envision a situation where the opening and closing of a leaf can be detected electronically. Once detected, the response would produce a consequence such as an airpuff or changes in light intensity.
    • Sean Nash
      Sean Nash on 23 Jun 23
       
      The remainder of this comprehensive article is to outline the main lines of research in this area:
  • Learning in Plants: Lessons from Mimosa pudica
    • Sean Nash
      Sean Nash on 23 Jun 23
       
      This well-compiled article does a really nice job of outlining the history of study regarding plant behavior. It also suggests model organisms for study. Mimosa is a favorite of mine as their response is VERY rapid and quite visible for a plant! There are all sorts of feasible project ideas that could arise from this area of research.
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