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Steve Bosserman

EXCLUSIVE: Chinese scientists are creating CRISPR babies - MIT Technology Review - 0 views

  • The new opinion poll, which was carried out by Sun Yat-Sen University, found wide support for gene editing among the sampled 4,700 Chinese, including a group of respondents who were HIV positive. More than 60% favored legalizing edited children if the objective was to treat or prevent disease. (Polls by the Pew Research Center have found similar levels support in the US for gene editing.)
  • He appeared to anticipate the concerns his study could provoke. “I support gene editing for the treatment and prevention of disease,” He posted in November to the social media site WeChat, “but not for enhancement or improving I.Q., which is not beneficial to society.” 
  • A person who knows He said his scientific ambitions appear to be in line with prevailing social attitudes in China, including the idea that the larger communal good transcends individual ethics and even international guidelines.
Steve Bosserman

Biology Will Be the Next Great Computing Platform - 0 views

  • Crispr, the powerful gene-editing tool, is revolutionizing the speed and scope with which scientists can modify the DNA of organisms, including human cells. So many people want to use it—from academic researchers to agtech companies to biopharma firms—that new companies are popping up to staunch the demand. Companies like Synthego, which is using a combination of software engineering and hardware automation to become the Amazon of genome engineering. And Inscripta, which wants to be the Apple. And Twist Bioscience, which could be the Intel
  • They’re betting biology will be the next great computing platform, DNA will be the code that runs it, and Crispr will be the programming language.
  • “Being able to do that in a parallel way is the novel part,” says Paul Dabrowski, who estimates that Synthego cuts down the time it takes for a scientists to perform gene edits from several months to just one.
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  • his company’s first move was to release a different gene-editing enzyme called MAD7—you can think of it like a Crispr/Cas9 knockoff, but legal—free for R&D uses. Inscripta will charge a single-digit royalty, far below market standards, to use MAD7 in manufacturing products or therapeutics.
  • We’re trying to get more people into the game now, by democratizing access to this family of enzymes,” he says. It’s a page from the Steve Jobs playbook; get them hooked on the MADzyme platform, down the line sell them personal hardware.
Steve Bosserman

Chinese researcher claims first gene-edited babies - 0 views

  • “I feel a strong responsibility that it’s not just to make a first, but also make it an example,” He told the AP. “Society will decide what to do next” in terms of allowing or forbidding such science.
Steve Bosserman

He Jiankui defends 'world's first gene-edited babies' - BBC News - 0 views

  • "If true, this experiment is monstrous. Gene editing itself is experimental and is still associated with off-target mutations, capable of causing genetic problems early and later in life, including the development of cancer," Prof Julian Savulescu, an ethics expert at the University of Oxford, told the BBC.
Steve Bosserman

The Chinese scientist who claims he made CRISPR babies is under investigation - MIT Tec... - 0 views

  • Separately, a group of 122 Chinese academics and scientists put out a statement condemning He’s research and calling on authorities to establish legal governance over gene editing. “This presents a major blow to the image and development of Chinese life sciences on the global stage,” they said. “It is extremely unfair for the many honest and sincere scholars working to adhere to moral practices in the sciences.”
  • In his video, He presented himself as a willing martyr to some higher cause. “I understand my work should be controversial, but families need this technology, and I am willing to take the criticism,” he said.
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