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Steve Bosserman

Biology Will Be the Next Great Computing Platform - 0 views

www.wired.com/...-next-great-computing-platform

crispr dna genetics biology

shared by Steve Bosserman on 06 May 18 - No Cached
  • Crispr, the powerful gene-editing tool, is revolutionizing the speed and scope with which scientists can modify the DNA of organisms, including human cells. So many people want to use it—from academic researchers to agtech companies to biopharma firms—that new companies are popping up to staunch the demand. Companies like Synthego, which is using a combination of software engineering and hardware automation to become the Amazon of genome engineering. And Inscripta, which wants to be the Apple. And Twist Bioscience, which could be the Intel
  • “Being able to do that in a parallel way is the novel part,” says Paul Dabrowski, who estimates that Synthego cuts down the time it takes for a scientists to perform gene edits from several months to just one.
  • They’re betting biology will be the next great computing platform, DNA will be the code that runs it, and Crispr will be the programming language.
  • ...2 more annotations...
  • his company’s first move was to release a different gene-editing enzyme called MAD7—you can think of it like a Crispr/Cas9 knockoff, but legal—free for R&D uses. Inscripta will charge a single-digit royalty, far below market standards, to use MAD7 in manufacturing products or therapeutics.
  • We’re trying to get more people into the game now, by democratizing access to this family of enzymes,” he says. It’s a page from the Steve Jobs playbook; get them hooked on the MADzyme platform, down the line sell them personal hardware.
Steve Bosserman

EXCLUSIVE: Chinese scientists are creating CRISPR babies - MIT Technology Review - 0 views

www.technologyreview.com/...sts-are-creating-crispr-babies

gene-editing crispr ethics decision-making

shared by Steve Bosserman on 26 Nov 18 - No Cached
  • The new opinion poll, which was carried out by Sun Yat-Sen University, found wide support for gene editing among the sampled 4,700 Chinese, including a group of respondents who were HIV positive. More than 60% favored legalizing edited children if the objective was to treat or prevent disease. (Polls by the Pew Research Center have found similar levels support in the US for gene editing.)
  • He appeared to anticipate the concerns his study could provoke. “I support gene editing for the treatment and prevention of disease,” He posted in November to the social media site WeChat, “but not for enhancement or improving I.Q., which is not beneficial to society.” 
  • A person who knows He said his scientific ambitions appear to be in line with prevailing social attitudes in China, including the idea that the larger communal good transcends individual ethics and even international guidelines.
Steve Bosserman

The Chinese scientist who claims he made CRISPR babies is under investigation - MIT Tec... - 0 views

www.technologyreview.com/...has-been-suspended-without-pay

gene-editing crispr ethics decision-making

shared by Steve Bosserman on 28 Nov 18 - No Cached
  • Separately, a group of 122 Chinese academics and scientists put out a statement condemning He’s research and calling on authorities to establish legal governance over gene editing. “This presents a major blow to the image and development of Chinese life sciences on the global stage,” they said. “It is extremely unfair for the many honest and sincere scholars working to adhere to moral practices in the sciences.”
  • In his video, He presented himself as a willing martyr to some higher cause. “I understand my work should be controversial, but families need this technology, and I am willing to take the criticism,” he said.
Bill Fulkerson

CRISPR-assisted novel method detects RNA-binding proteins in living cells - 0 views

phys.org/...na-binding-proteins-cells.html

novel proteins cells method CRISPR

shared by Bill Fulkerson on 01 Jul 20 - No Cached
  • Bill Fulkerson on 01 Jul 20
     
    While scientists still don't fully understand the diverse nature of RNA molecules, it is believed that the proteins binding to them, called RNA-binding proteins, are associated with many types of disease formation. Research led by biomedical scientists from City University of Hong Kong (CityU) has led to a novel detection method, called CARPID, to identify binding proteins of specific RNAs in living cells. It is expected that the innovation can be applied in various types of cell research, from identifying biomarkers of cancer diagnosis to detecting potential drug targets for treating viral diseases.
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