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Steve Bosserman

EXCLUSIVE: Chinese scientists are creating CRISPR babies - MIT Technology Review - 0 views

www.technologyreview.com/...sts-are-creating-crispr-babies

gene-editing crispr ethics decision-making

shared by Steve Bosserman on 26 Nov 18 - No Cached
  • The new opinion poll, which was carried out by Sun Yat-Sen University, found wide support for gene editing among the sampled 4,700 Chinese, including a group of respondents who were HIV positive. More than 60% favored legalizing edited children if the objective was to treat or prevent disease. (Polls by the Pew Research Center have found similar levels support in the US for gene editing.)
  • He appeared to anticipate the concerns his study could provoke. “I support gene editing for the treatment and prevention of disease,” He posted in November to the social media site WeChat, “but not for enhancement or improving I.Q., which is not beneficial to society.” 
  • A person who knows He said his scientific ambitions appear to be in line with prevailing social attitudes in China, including the idea that the larger communal good transcends individual ethics and even international guidelines.
Steve Bosserman

Biology Will Be the Next Great Computing Platform - 0 views

www.wired.com/...-next-great-computing-platform

crispr dna genetics biology

shared by Steve Bosserman on 06 May 18 - No Cached
  • Crispr, the powerful gene-editing tool, is revolutionizing the speed and scope with which scientists can modify the DNA of organisms, including human cells. So many people want to use it—from academic researchers to agtech companies to biopharma firms—that new companies are popping up to staunch the demand. Companies like Synthego, which is using a combination of software engineering and hardware automation to become the Amazon of genome engineering. And Inscripta, which wants to be the Apple. And Twist Bioscience, which could be the Intel
  • They’re betting biology will be the next great computing platform, DNA will be the code that runs it, and Crispr will be the programming language.
  • “Being able to do that in a parallel way is the novel part,” says Paul Dabrowski, who estimates that Synthego cuts down the time it takes for a scientists to perform gene edits from several months to just one.
  • ...2 more annotations...
  • his company’s first move was to release a different gene-editing enzyme called MAD7—you can think of it like a Crispr/Cas9 knockoff, but legal—free for R&D uses. Inscripta will charge a single-digit royalty, far below market standards, to use MAD7 in manufacturing products or therapeutics.
  • We’re trying to get more people into the game now, by democratizing access to this family of enzymes,” he says. It’s a page from the Steve Jobs playbook; get them hooked on the MADzyme platform, down the line sell them personal hardware.
Steve Bosserman

Situational Assessment 2017: Trump Edition - Deep Code - Medium - 0 views

medium.com/...017-trump-edition-d189d24fc046

deep code insurgency globalization neoliberalism john robb

shared by Steve Bosserman on 02 Feb 17 - No Cached
  • I use John Robb’s term “Trump Insurgency” here to highlight the fact that the election of 2016 was not an example of “ordinary politics”. Anyone who fails to understand this is going to be making significant errors. For example, the 2016 election is not comparable to the 2000 election (e.g., merely a “close” election) nor to the 1980 election (e.g., an “ideological transition” election). While it is tempting to compare it to 1860, I’m not sure that is a good match either.In fact, as I go back and try to do pattern matching, the only real pattern I can find is the 1776 “election” (AKA the American Revolution). In other words, while 2016 still formally looked like politics, what is really going on here is a revolutionary war. For now this is war using memes rather than bullets, but war is much more than a metaphor.
Bill Fulkerson

Anatomy of an AI System - 1 views

anatomyof.ai

AI amazon

shared by Bill Fulkerson on 14 Sep 18 - No Cached
  • Bill Fulkerson on 14 Sep 18
     
    "With each interaction, Alexa is training to hear better, to interpret more precisely, to trigger actions that map to the user's commands more accurately, and to build a more complete model of their preferences, habits and desires. What is required to make this possible? Put simply: each small moment of convenience - be it answering a question, turning on a light, or playing a song - requires a vast planetary network, fueled by the extraction of non-renewable materials, labor, and data. The scale of resources required is many magnitudes greater than the energy and labor it would take a human to operate a household appliance or flick a switch. A full accounting for these costs is almost impossible, but it is increasingly important that we grasp the scale and scope if we are to understand and govern the technical infrastructures that thread through our lives. III The Salar, the world's largest flat surface, is located in southwest Bolivia at an altitude of 3,656 meters above sea level. It is a high plateau, covered by a few meters of salt crust which are exceptionally rich in lithium, containing 50% to 70% of the world's lithium reserves. 4 The Salar, alongside the neighboring Atacama regions in Chile and Argentina, are major sites for lithium extraction. This soft, silvery metal is currently used to power mobile connected devices, as a crucial material used for the production of lithium-Ion batteries. It is known as 'grey gold.' Smartphone batteries, for example, usually have less than eight grams of this material. 5 Each Tesla car needs approximately seven kilograms of lithium for its battery pack. 6 All these batteries have a limited lifespan, and once consumed they are thrown away as waste. Amazon reminds users that they cannot open up and repair their Echo, because this will void the warranty. The Amazon Echo is wall-powered, and also has a mobile battery base. This also has a limited lifespan and then must be thrown away as waste. According to the Ay
Steve Bosserman

Chinese researcher claims first gene-edited babies - 0 views

www.apnews.com/97bb7aa36c45449b488e19ac83e86d

gene-editing crispr ethics decision-making

shared by Steve Bosserman on 26 Nov 18 - No Cached
  • “I feel a strong responsibility that it’s not just to make a first, but also make it an example,” He told the AP. “Society will decide what to do next” in terms of allowing or forbidding such science.
Steve Bosserman

He Jiankui defends 'world's first gene-edited babies' - BBC News - 0 views

www.bbc.com/...world-asia-china-46368731

shared by Steve Bosserman on 28 Nov 18 - No Cached
  • "If true, this experiment is monstrous. Gene editing itself is experimental and is still associated with off-target mutations, capable of causing genetic problems early and later in life, including the development of cancer," Prof Julian Savulescu, an ethics expert at the University of Oxford, told the BBC.
Steve Bosserman

The Chinese scientist who claims he made CRISPR babies is under investigation - MIT Tec... - 0 views

www.technologyreview.com/...has-been-suspended-without-pay

gene-editing crispr ethics decision-making

shared by Steve Bosserman on 28 Nov 18 - No Cached
  • Separately, a group of 122 Chinese academics and scientists put out a statement condemning He’s research and calling on authorities to establish legal governance over gene editing. “This presents a major blow to the image and development of Chinese life sciences on the global stage,” they said. “It is extremely unfair for the many honest and sincere scholars working to adhere to moral practices in the sciences.”
  • In his video, He presented himself as a willing martyr to some higher cause. “I understand my work should be controversial, but families need this technology, and I am willing to take the criticism,” he said.
Bill Fulkerson

Why a 400-Year Program of Modernist Thinking is Exploding | naked capitalism - 0 views

www.nakedcapitalism.com/...ernist-thinking-exploding.html

capitalism power society

shared by Bill Fulkerson on 11 Mar 17 - No Cached
  • Bill Fulkerson on 11 Mar 17
     
    " Fearless commentary on finance, economics, politics and power Follow yvessmith on Twitter Feedburner RSS Feed RSS Feed for Comments Subscribe via Email SUBSCRIBE Recent Items Links 3/11/17 - 03/11/2017 - Yves Smith Deutsche Bank Tries to Stay Alive - 03/11/2017 - Yves Smith John Helmer: Australian Government Trips Up Ukrainian Court Claim of MH17 as Terrorism - 03/11/2017 - Yves Smith 2:00PM Water Cooler 3/10/2017 - 03/10/2017 - Lambert Strether Why a 400-Year Program of Modernist Thinking is Exploding - 03/10/2017 - Yves Smith Links 3/10/17 - 03/10/2017 - Yves Smith Why It Will Take a Lot More Than a Smartphone to Get the Sharing Economy Started - 03/10/2017 - Yves Smith CalPERS' General Counsel Railroads Board on Fiduciary Counsel Selection - 03/10/2017 - Yves Smith Another Somalian Famine - 03/10/2017 - Yves Smith Trade now with TradeStation - Highest rated for frequent traders Why a 400-Year Program of Modernist Thinking is Exploding Posted on March 10, 2017 by Yves Smith By Lynn Parramore, Senior Research Analyst at the Institute for New Economic Thinking. Originally published at the Institute for New Economic Thinking website Across the globe, a collective freak-out spanning the whole political system is picking up steam with every new "surprise" election, rush of tormented souls across borders, and tweet from the star of America's great unreality show, Donald Trump. But what exactly is the force that seems to be pushing us towards Armageddon? Is it capitalism gone wild? Globalization? Political corruption? Techno-nightmares? Rajani Kanth, a political economist, social thinker, and poet, goes beyond any of these explanations for the answer. In his view, what's throwing most of us off kilter - whether we think of ourselves as on the left or right, capitalist or socialist -was birthed 400 years ago during the period of the Enlightenment. It's a set of assumptions, a particular way of looking at the world that pushed out previous modes o
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