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Bill Fulkerson

DNA damage caused by migrating light energy - 0 views

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    Ultraviolet light endangers the integrity of human genetic information and may cause skin cancer. For the first time, researchers at Karlsruhe Institute of Technology (KIT) have demonstrated that DNA damage may also occur far away from the point of incidence of the radiation. They produced an artificially modeled DNA sequence in new architecture and succeeded in detecting DNA damage at a distance of 30 DNA building blocks. The results are reported in Angewandte Chemie.
Bill Fulkerson

A new twist on DNA origami: Meta-DNA structures transform the DNA nanotechnology world - 0 views

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    team of scientists from ASU and Shanghai Jiao Tong University (SJTU) led by Hao Yan, ASU's Milton Glick Professor in the School of Molecular Sciences, and director of the ASU Biodesign Institute's Center for Molecular Design and Biomimetics, has just announced the creation of a new type of meta-DNA structures that will open up the fields of optoelectronics (including information storage and encryption) as well as synthetic biology.
Steve Bosserman

About - Catalog - 0 views

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    "We are developing next generation technology to store digital information in DNA molecules. Our vision is to fit the information content of entire data centers in the palm of your hand. We have proven our approach to encoding data in DNA and are in the process of scaling up our platform. CATALOG technology will make it economically attractive to use DNA as a medium for long-term archival of data."
Bill Fulkerson

Reverse Engineering the source code of the BioNTech/Pfizer SARS-CoV-2 Vaccine - Articles - 0 views

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    RNA is the volatile 'working memory' version of DNA. DNA is like the flash drive storage of biology. DNA is very durable, internally redundant and very reliable. But much like computers do not execute code directly from a flash drive, before something happens, code gets copied to a faster, more versatile yet far more fragile system.
Bill Fulkerson

Environmentally-Caused Disease Crisis? Pesticide Damage to DNA Found 'Programmed' Into ... - 0 views

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    "Epigenetic Changes Programmed Into Future Generations But the most disturbing finding was that atrazine had epigenetic effects. Epigenetics is the theory that environmental factors, such as diet, lifestyle choices and pesticides can impact the health of people who are exposed to them and also their descendants. Human DNA, according to epigenetics, is not unchangeable; it can be altered by such environmental factors. Epigenetic changes can be imprinted on the DNA of a fetus during pregnancy according to Winchester."
Steve Bosserman

Biology Will Be the Next Great Computing Platform - 0 views

  • Crispr, the powerful gene-editing tool, is revolutionizing the speed and scope with which scientists can modify the DNA of organisms, including human cells. So many people want to use it—from academic researchers to agtech companies to biopharma firms—that new companies are popping up to staunch the demand. Companies like Synthego, which is using a combination of software engineering and hardware automation to become the Amazon of genome engineering. And Inscripta, which wants to be the Apple. And Twist Bioscience, which could be the Intel
  • They’re betting biology will be the next great computing platform, DNA will be the code that runs it, and Crispr will be the programming language.
  • “Being able to do that in a parallel way is the novel part,” says Paul Dabrowski, who estimates that Synthego cuts down the time it takes for a scientists to perform gene edits from several months to just one.
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  • his company’s first move was to release a different gene-editing enzyme called MAD7—you can think of it like a Crispr/Cas9 knockoff, but legal—free for R&D uses. Inscripta will charge a single-digit royalty, far below market standards, to use MAD7 in manufacturing products or therapeutics.
  • We’re trying to get more people into the game now, by democratizing access to this family of enzymes,” he says. It’s a page from the Steve Jobs playbook; get them hooked on the MADzyme platform, down the line sell them personal hardware.
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