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Holly Barlaam

Cow Digestion - 67 views

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    How a cow makes milk and meat from things we cannot eat! Super cute animation showing a cow's four stomachs. Students will especially like the cow pie part. :)
C CC

Resource: Why Do We Get Nervous? | UKEdChat.com - Supporting the #UKEdChat Education Co... - 27 views

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    A great video from ASAPScience exploring why we experience butterflies in our stomachs
Angela Hagan

Aspirin stimulates insulin - 6 views

  • AbstractNormal subjects and patients with adult-onset diabetes received 10 gm. of aspirin in four days. On the fourth day, the fasting serum glucose and the glucose response to oral glucose were decreased in both groups. These changes were associated with increased levels of serum insulin and pancreatic glucagon, although the glucagon responses to oral glucose were unchanged. In the diabetic patients, aspirin therapy was followed by a decreased glucose response to I.V. glucose and by the appearance of an early insulin peak, which could not be demonstrated before treatment. Aspirin did not affect the I.V. glucose tolerance in normal subjects, although it did enhance the early insulin peak. A decrease in the fasting levels of free fatty acids was noted in both groups, whereas the fasting level of triglycerides decreased only in the diabetic patients. Cholesterolemia did not change in either group. A few preliminary observations indicate that, in normal subjects, ibuprofen and ketoprofen, two other presumed prostaglandin inhibitors, did not affect fasting glycemia, glucose tolerance, or the insulin response to glucose. No changes were noted after the administration of placebo. Last A1C 4.8No Rx, Diet modification, exercise, Supps and HerbalsI am a retired HYPOGLYCEMIC Reply With Quote 11-08-2010 #2 trinitarian3n1 D.D. Family Moderator Join Date November 2007 Location In the mitten, USA Age 41 Posts > 100 About T2 dx 3/07, tx w/very lo carb D&E Met, bolus R Blog Entries 127 That's a hefty dose of aspirin. John C.A clean house is the sign of a broken computer.Last HgbA1c - 5.5% 2/2011 Reply With Quote 11-08-2010 #3 MCS D.D. Family Join Date August 2010 Posts > 100 About T2, trying to live a healthy life Yes it is, 650mg 4 times a day. I wonder if they did that to make sure they had a response and if there is a break point of some lower dose. I am on 325 once a day now. Been that high in the past for other things, lots of ringing in the ears when you get that high of a dose. Last A1C 4.8No Rx, Diet modification, exercise, Supps and HerbalsI am a retired HYPOGLYCEMIC Reply With Quote 11-08-2010 #4 furball64801 D.D. Family Join Date December 2009 Posts > 100 About type 2 25 yrs mother aunt type 2 thin 50 yrs Blog Entr
  • The therory is that it helps to regenerate the once turned off Beta cells, not over working the exiting ones. This is just one article I found, they are many, most of them concern Salsalate a drug used for arthritis. It works by lowering the inflammation of the liver and pancreas. Lowers IR, its a pretty interesting concept based largerly on inflammation of one muscles and organs. Originally Posted by jeanne wagner i know for heart health they recommend the baby 81 mg a day. I would think you wouldn't have a stomach lining left if you took that on a daily basis. Also just because it stimulates insulin doesn't mean it is a good thing. Sulfonyureas also overstimulate insulin and there is some thought they lead to beta cell burnout. I think it is better to find things like metformin that make you more sensitive to the insulin you naturally make. Last A1C 4.8No Rx, Diet modification, exercise, Supps and HerbalsI am a retired HYPOGLYCEMIC Reply With Quote 11-08-2010 #7 MCS D.D. Family Join Date August 2010 Posts > 100 About T2, trying to live a healthy life Here is a few more articles concerning NSAID's and insulin if you are interested.http://www.annals.org/content/152/6/346.abstracthttp://onlinelibrary.wiley.com/doi/1...026.x/abstracthttp://www.theannals.com/cgi/content/abstract/44/7/1207 Last A1C 4.8No Rx, Diet modification, exercise, Supps and HerbalsI am a retired HYPOGLYCEMIC Reply With Quote MCS was thanked for this post by: Nan-OH 11-08-2010 #8 CalgaryDiabetic D.D. Family Join Date June 2009 Location Calgary,Canada Posts > 100 About diabetic since 1997, on insulin 2000 Guarantied tummy ulcer with so much aspirin. Reply With Quote 11-09-2010 #9 MCS
Holly Barlaam

The Body Explained - 156 views

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    Information on common simple body questions. Includes what causes your stomach to growl, why does your nose run when you cry, why your teeth chatter when you are cold, what causes blushing, and more.
Kristen Hewett

Upton Sinclair Hits His Readers in the Stomach - 0 views

    • Kristen Hewett
       
      This means that he researched how animals were killed and processed to be sold as food
GP withMdmLin

Abortion laws cannot hinge on when life 'begins' - 15 views

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    In his letter, "Arguments that should be aborted" (April 3), Mr Devathas Satianathan states that it is unclear how Associate Professor Tan Seow Hon's religious view is relevant. From Edwin Dai Weiyun - 03 April In his letter, "Arguments that should be aborted" (April 3), Mr Devathas Satianathan states that it is unclear how Associate Professor Tan Seow Hon's religious view is relevant. However, I would ask if her premise is that life begins at six weeks from conception, or possibly earlier, an interpretation that would be informed by her religious views. To say that her view on this has no bearing on her commentary is intellectual dishonesty. She also cited recent legislative developments in North Dakota, a Bible Belt state. Mr Jason Cheng responded, in "Let pregnant women make their own moral choices" (April 2), that six weeks is insufficient time for women to detect their pregnancy, which basically results in a de facto ban on abortion. Mr Devathas argues that, in the balance between preserving a baby's life and a mother's choice, Mr Cheng fails to acknowledge the former. Ironically, Mr Devathas fails to acknowledge the latter. Where he discusses a valid point is in the question: When does life begin? Answers to such a question, though, are varied across society and influenced by the religious views, or a lack thereof, of the individual. It is unwise and unconstitutional for the State to legislate or endorse the moral views of any religious group over other members of society. People who hold strong pro-life views are free to bring their babies to full term. The same liberty should be accorded to people who hold pro-choice views."
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    This does not seems to be educational but maybe I misunderstood what would be fed to me through diigo. In any event since it come through, I pose this philosophical non-religious question: If you were 2 weeks pregnant and I punched you in the stomach which in turn killed the fetus, it would definitely be assault on you, but should I be criminally responsible for the fetus? If so, why?
Kenuvis Romero

Psilocybin (magic mushrooms) - 0 views

  • The biosinthetic path that allow Psilocybin to be produced by mushrooms is as follow:
  • The several analogyes with triptophan aminoacid, with whom psilocybin has common origines are probably at the base of psilocybin ability to induced psychedelich alteration on humans.
  • Amino acids, including tryptophan, act as building blocks in protein biosynthesis. In addition, tryptophan functions as a biochemical precursor for many compounds like serotonin Serotonin (a neurotransmitter), synthesized via tryptophan hydroxylase. Serotonin, in turn, can be converted to melatonin (a neurohormone), via N-acetyltransferase and 5-hydroxyindole-O-methyltransferase activities
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  • it's been noticed that psilocyn can indirectly raise dopamine concentration withing the basal ganglia.
  • Almost 50% of oral psilocybin is absorbed by stomach and gut; from here is lead to liver, where it's converted in psilocin, pharmacologically active form, that can furtherly be glucoronated and escreted with urine or converted in other psilocinics metabolites.
  • In rats, the median lethal dose (LD50) when administered orally is 280 milligrams per kilogram (mg/kg), approximately one and a half times that of caffeine. When administered intravenously in rabbits, psilocybin's LD50 is approximately 12.5 mg/kg
  • traces of the compund can be detected in unine even after 7 days.
  • Clinical studies show that psilocin concentrations in the plasma of adults average about 8 µg/liter within 2 hours after ingestion of a single 15 mg oral psilocybin dose; psychological effects occur with a blood plasma concentration of 4–6 µg/liter. Psilocybin is about 100 times less potent than LSD on a weight per weight basis, and the physiological effects last about half as long.
  • Within 24 hours from administration 65% of the alucinogen is escreted by urine, while another 15-20% is excreted by bile and feces.
  • Monoamine oxidase inhibitors (MAOI) have been known to prolong and enhance the effects of psilocybin. Alcohol consumption may enhance the effects of psilocybin, because acetaldehyde, one of the primary breakdown metabolites of consumed alcohol, reacts with biogenic amines present in the body to produce MAOIs related to tetrahydroisoquinoline and β-carboline. Tobacco smokers can also experience more powerful effects with psilocybin, because tobacco smoke exposure decreases levels of MAO in the brain and peripheral organs.
  • This could lead to a lower usage o f glucose, but the same study admitted an increase glucose usage by the whole brain cell, meaning a differente use of this sugar while the drug is having effects.
  • use of MRI (functional magnetic resounance) showed that the decresed blood flow associate with decreasing in neural activity. A simple explanation for this unexpected situation could be the serotoning agonist action of psilocybin, action that seems to be focused more on 5-HT receptors than on 5-HT2A.
  • psilocibyn is able to act as a 5-HT agonist binding directly its receptors.
  • augmented glucose consumption in several brain regions; this lead to the conclusion that psilocybin is some way able to modify the physiological glucosal metabolic rate of our body
  • The strong inibition of the PCC is now thought to be most significant action of psilocybin on neural disaccoppiation
    • Kenuvis Romero
       
      Lower brain glucose metabolism is linked with increased capacity for working memory.
  • Psilocybin comprises approximately 1% of the weight of Psilocybe cubensis mushrooms, and so nearly 1.7 kilograms (3.7 lb) of dried mushrooms, or 17 kilograms (37 lb) of fresh mushrooms, would be required for a 60-kilogram (130 lb) person to reach the 280 mg/kg LD50 value.
  • psilocybin can cause anxiety and increased heart rate and BP which is very counter- productive for someone on metoprolol and micardis.
  • propose the possibility to use psilocybin as a palliative therapy for terminal illness like cancer but also as a real antidepressive active principle available for the family of the patient. The rational is foundable in the fact that we usually administer SSRI as antidepressive agents, so psilocibyn sholud be useful in this purpose for its selective agonist action on 5-HT2A receptors
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