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Home/ Diigo In Education/ Contents contributed and discussions participated by Kenuvis Romero

Contents contributed and discussions participated by Kenuvis Romero

Kenuvis Romero

CIA, MK Ultra & Origins Of Acid Counter Culture, Jan Irvin, Joe Atwill 16May2013 - YouTube - 1 views

  • rule of non--contradiction that A=A and cannot be non-A. Any MEANINGFUL investigation of natural phenomena violates the out-moded straightjacket of Classical Logic.
Kenuvis Romero

Occult - Wikipedia, the free encyclopedia - 2 views

  • The occult (from the Latin word occultus "clandestine, hidden, secret") is "knowledge of the hidden".[1]
Kenuvis Romero

Trigorin comments on What, if any, drug abuse existed in the medieval world? Did it dif... - 17 views

  • Byzantine Empire was much more intense than any of these guys. There are countless hagiographies to study and lets just say that when a saint had an ecstatic religious moment, he most likely had a little help.
Kenuvis Romero

Insula (building) - Wikipedia, the free encyclopedia - 0 views

  • In Roman architecture, an insula (Latin for "island," plural insulae) was a kind of apartment building that housed most of the urban citizen population of ancient Rome, including ordinary people of lower- or middle-class status (the plebs) and all but the wealthiest from the upper-middle class (the equites). The traditional elite and the very wealthy lived in domus, large single-family residences, but the two kinds of housing were intermingled in the city and not segregated into separate neighborhoods.[1] The ground-level floor of the insula was used for tabernae, shops and businesses, with the living space upstairs. Like modern apartment buildings, an insula might have a name, usually referring to the owner of the building.[2]
Kenuvis Romero

New Discoveries on Optimizing Memory Formation | Psychology Today - 2 views

  • In summary, memory optimization would seem to require one to:Create associations that can serve as memory cues.Place a high value on the cues and their targets.Repeatedly present the cues and replay the initial information. When awake, present the cues in self-test mode. When asleep, even better results would obtain if cues were presented at a level that does not cause awakening during the early night sleep when sleep is deepest and there is little dreaming.
Kenuvis Romero

Journal of Cerebral Blood Flow & Metabolism - Multiple Microvascular and Astroglial 5-H... - 0 views

  • Physiologic and anatomic evidence suggest that 5-hydroxytryptamine (5-HT) neurons regulate local cerebral blood flow and blood-brain barrier permeability.
  • capillary endothelial cells exhibited mRNA for the h5-HT1D and for the 5-HT7 receptors whereas microvascular smooth muscle cells, in addition to h5-HT1D and 5-HT7, also showed polymerase chain reaction products for h5-HT1B receptors. Expression of 5-HT1F and 5-HT2A receptor mRNAs was never detected in any of the microvascular cell cultures. In contrast, messages for all 5-HT receptors tested were detected in human brain astrocytes with a predominance of the 5-HT2A and 5-HT7 subtypes. In all cultures, sumatriptan inhibited (35–58%, P < .05) the forskolin-stimulated production of cyclic AMP, an effect blocked by the 5-HT1B/1D receptor antagonists GR127935 and GR55562. In contrast, 5-carboxamidotryptamine induced strong increases (≥ 400%, P < .005) in basal cyclic AMP levels that were abolished by mesulergine, a nonselective 5-HT7 receptor antagonist. Only astroglial cells showed a ketanserin-sensitive increase (177%, P < .05) in IP3 formation when exposed to 5-HT. These results show that specific populations of functional 5-HT receptors are differentially distributed within the various cellular compartments of the human cortical microvascular bed, and that human brain astroglial cells are endowed with multiple 5-HT receptors. These findings emphasize the complex interactions between brain serotonergic pathways and non-neuronal cells within the CNS and, further, they raise the possibility that some of these receptors may be activated by antimigraine compounds such as brain penetrant triptan derivatives.
Kenuvis Romero

The Cingulate Cortex Does Everything - YouTube - 1 views

  • our model predicts that the the cingulate will overtake the PFC within ten years. I can send you the spreadsheet if you like. Also, the prefrontal cortex is typically considered any neocortex that lies anterior to the precentral gyrus (motor cortex), so, the anterior cingulate is actually part of the PFC!
  • the prefrontal cortex is typically considered any neocortex that lies anterior to the precentral gyrus (motor cortex), so, the anterior cingulate is actually part of the PFC!
Kenuvis Romero

This is your brain on psilocybin… | The Scicurious Brain, Scientific American... - 0 views

  • the authors cite a large body of literature characterizing 5-HT2a agonism resulting in pyramidal cell inhibition in cortical areas via excitation of GABAergic interneurons that synapse on pyramidal cells.
  • increased blood deoxygenation levels is concretely correlated with neuronal action-potentions; inhibition of neurons results in less APs and thus less blood flow. BOLD contrasts are the basis of fMRI studies–all of them would be invalidated if this were refuted.
Kenuvis Romero

Psilocybin (magic mushrooms) - 0 views

  • The biosinthetic path that allow Psilocybin to be produced by mushrooms is as follow:
  • The several analogyes with triptophan aminoacid, with whom psilocybin has common origines are probably at the base of psilocybin ability to induced psychedelich alteration on humans.
  • Amino acids, including tryptophan, act as building blocks in protein biosynthesis. In addition, tryptophan functions as a biochemical precursor for many compounds like serotonin Serotonin (a neurotransmitter), synthesized via tryptophan hydroxylase. Serotonin, in turn, can be converted to melatonin (a neurohormone), via N-acetyltransferase and 5-hydroxyindole-O-methyltransferase activities
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  • it's been noticed that psilocyn can indirectly raise dopamine concentration withing the basal ganglia.
  • Almost 50% of oral psilocybin is absorbed by stomach and gut; from here is lead to liver, where it's converted in psilocin, pharmacologically active form, that can furtherly be glucoronated and escreted with urine or converted in other psilocinics metabolites.
  • In rats, the median lethal dose (LD50) when administered orally is 280 milligrams per kilogram (mg/kg), approximately one and a half times that of caffeine. When administered intravenously in rabbits, psilocybin's LD50 is approximately 12.5 mg/kg
  • traces of the compund can be detected in unine even after 7 days.
  • Clinical studies show that psilocin concentrations in the plasma of adults average about 8 µg/liter within 2 hours after ingestion of a single 15 mg oral psilocybin dose; psychological effects occur with a blood plasma concentration of 4–6 µg/liter. Psilocybin is about 100 times less potent than LSD on a weight per weight basis, and the physiological effects last about half as long.
  • Monoamine oxidase inhibitors (MAOI) have been known to prolong and enhance the effects of psilocybin. Alcohol consumption may enhance the effects of psilocybin, because acetaldehyde, one of the primary breakdown metabolites of consumed alcohol, reacts with biogenic amines present in the body to produce MAOIs related to tetrahydroisoquinoline and β-carboline. Tobacco smokers can also experience more powerful effects with psilocybin, because tobacco smoke exposure decreases levels of MAO in the brain and peripheral organs.
  • Within 24 hours from administration 65% of the alucinogen is escreted by urine, while another 15-20% is excreted by bile and feces.
  • Psilocybin comprises approximately 1% of the weight of Psilocybe cubensis mushrooms, and so nearly 1.7 kilograms (3.7 lb) of dried mushrooms, or 17 kilograms (37 lb) of fresh mushrooms, would be required for a 60-kilogram (130 lb) person to reach the 280 mg/kg LD50 value.
  • This could lead to a lower usage o f glucose, but the same study admitted an increase glucose usage by the whole brain cell, meaning a differente use of this sugar while the drug is having effects.
  • use of MRI (functional magnetic resounance) showed that the decresed blood flow associate with decreasing in neural activity. A simple explanation for this unexpected situation could be the serotoning agonist action of psilocybin, action that seems to be focused more on 5-HT receptors than on 5-HT2A.
  • psilocibyn is able to act as a 5-HT agonist binding directly its receptors.
  • augmented glucose consumption in several brain regions; this lead to the conclusion that psilocybin is some way able to modify the physiological glucosal metabolic rate of our body
    • Kenuvis Romero
       
      Lower brain glucose metabolism is linked with increased capacity for working memory.
  • The strong inibition of the PCC is now thought to be most significant action of psilocybin on neural disaccoppiation
  • psilocybin can cause anxiety and increased heart rate and BP which is very counter- productive for someone on metoprolol and micardis.
  • propose the possibility to use psilocybin as a palliative therapy for terminal illness like cancer but also as a real antidepressive active principle available for the family of the patient. The rational is foundable in the fact that we usually administer SSRI as antidepressive agents, so psilocibyn sholud be useful in this purpose for its selective agonist action on 5-HT2A receptors
Kenuvis Romero

Art of memory - Wikipedia, the free encyclopedia - 0 views

  • The Art of Memory or Ars Memoriae ("art of memory" in Latin) is a general term used to designate a loosely associated group of mnemonic principles and techniques used to organize memory impressions, improve recall, and assist in the combination and 'invention' of ideas. An alternative and frequently used term is "Ars Memorativa" which is also often translated as "art of memory" although its more literal meaning is "Memorative Art". It is sometimes referred to as mnemotechnics.[1] It is an 'art' in the Aristotelian sense, which is to say a method or set of prescriptions that adds order and discipline to the pragmatic, natural activities of human beings.[2] It has existed as a recognized group of principles and techniques since at least as early as the middle of the first millennium BCE,[3] and was usually associated with training in rhetoric or logic, but variants of the art were employed in other contexts, particularly the religious and the magical. Techniques commonly employed in the art include the association of emotionally striking memory images within visualized locations, the chaining or association of groups of images, the association of images with schematic graphics or notae ("signs, markings, figures" in Latin), and the association of text with images. Any or all of these techniques were often used in combination with the contemplation or study of architecture, books, sculpture and painting, which were seen by practitioners of the art of memory as externalizations of internal memory images and/or organization.
Kenuvis Romero

The Art of Memory - Wikipedia, the free encyclopedia - 0 views

  • The Art of Memory From Wikipedia, the free encyclopedia Jump to: navigation, search For the general topic known as "Ars memoriae" or "the Art of Memory", see Art of memory. The Art of Memory Author(s) Frances A. Yates Country United Kingdom Language English Publisher Routledge and Kegan Paul Publication date 1966 Media type Print (book) Pages 400 ISBN 0-226-95001-8 OCLC Number 42905743  Preceded by Giordano Bruno and the Hermetic Tradition The Art of Memory is a 1966 non-fiction book by British historian Frances A. Yates. The book follows the history of mnemonic systems from the classical period of Simonides of Ceos in Ancient Greece to the Renaissance era of Giordano Bruno, ending with Gottfried Leibniz and the early emergence of the scientific method in the 17th century. See also [edit] Method of loci John Crowley Art of Memory
Kenuvis Romero

Method of loci - Wikipedia, the free encyclopedia - 0 views

  • The Method of Loci (plural of Latin locus for place or location), also called the memory palace, is a mnemonic device introduced in ancient Roman and Greek rhetorical treatises (in the anonymous Rhetorica ad Herennium, Cicero's De Oratore, and Quintilian's Institutio oratoria). The items to be remembered in this mnemonic system are mentally associated with specific physical locations.[1] It relies on memorized spatial relationships to establish, order and recollect memorial content. The term is most often found in specialised works on psychology, neurobiology and memory, though it was used in the same general way at least as early as the first half of the nineteenth century in works on rhetoric, logic and philosophy.[2]
Kenuvis Romero

John Crowley - Wikipedia, the free encyclopedia - 0 views

  • John Crowley (born December 1, 1942) is an American author of fantasy, science fiction and mainstream fiction. He studied at Indiana University and has a second career as a documentary film writer. He is best known as the author of Little, Big (1981), which received the World Fantasy Award for Best Novel and has been called "a neglected masterpiece" by Harold Bloom[3] and his Aegypt series of novels which revolve around the same themes of Hermeticism, memory, families and religion.
Kenuvis Romero

Memory - Wikipedia, the free encyclopedia - 0 views

  • Encoding of working memory involves the spiking of individual neurons induced by sensory input, which persists even after the sensory input disappears (Jensen and Lisman 2005; Fransen et al. 2002). Encoding of episodic memory involves persistent changes in molecular structures that alter synaptic transmission between neurons. Examples of such structural changes include long-term potentiation (LTP) or spike-timing-dependent plasticity (STDP). The persistent spiking in working memory can enhance the synaptic and cellular changes in the encoding of episodic memory (Jensen and Lisman 2005).
  • Recent functional imaging studies detected working memory signals in both medial temporal lobe (MTL), a brain area strongly associated with long-term memory, and prefrontal cortex (Ranganath et al. 2005), suggesting a strong relationship between working memory and long-term memory. However, the substantially more working memory signals seen in the prefrontal lobe suggest that this area play a more important role in working memory than MTL (Suzuki 2007).
  • Consolidation and reconsolidation. Short-term memory (STM) is temporary and subject to disruption, while long-term memory (LTM), once consolidated, is persistent and stable. Consolidation of STM into LTM at the molecular level presumably involves two processes: synaptic consolidation and system consolidation. The former involves a protein synthesis process in the medial temporal lobe (MTL), whereas the latter transforms the MTL-dependent memory into an MTL-independent memory over months to years (Ledoux 2007). In recent years, such traditional consolidation dogma has been re-evaluated as a result of the studies on reconsolidation. These studies showed that prevention after retrieval affects subsequent retrieval of the memory (Sara 2000). New studies have shown that post-retrieval treatment with protein synthesis inhibitors and many other compounds can lead to an amnestic state (Nadel et al. 2000b; Alberini 2005; Dudai 2006). These findings on reconsolidation fit with the behavioral evidence that retrieved memory is not a carbon copy of the initial experiences, and memories are updated during retrieval.
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  • Physical exercise, particularly continuous aerobic exercises such as running, cycling and swimming, has many cognitive benefits and effects on the brain. Influences on the brain include increases in neurotransmitter levels, improved oxygen and nutrient delivery, and increased neurogenesis in the hippocampus. The effects of exercise on memory have important implications for improving children's academic performance, maintaining mental abilities in old age, and the prevention and potential cure of neurological diseases.
  • At the Center for Cognitive Science at Ohio State University, researchers have found that memory accuracy of adults is hurt by the fact that they know more, and have more experience than children, and tend to apply all this knowledge when learning new information. The findings appeared in the August 2004 edition of the journal Psychological Science.
  • Interference can hamper memorization and retrieval. There is retroactive interference, when learning new information makes it harder to recall old information[59] and proactive interference, where prior learning disrupts recall of new information. Although interference can lead to forgetting, it is important to keep in mind that there are situations when old information can facilitate learning of new information. Knowing Latin, for instance, can help an individual learn a related language such as French – this phenomenon is known as positive transfer.[60]
  • Methods to optimize memorization[edit] Memorization is a method of learning that allows an individual to recall information verbatim. Rote learning is the method most often used. Methods of memorizing things have been the subject of much discussion over the years with some writers, such as Cosmos Rossellius using visual alphabets. The spacing effect shows that an individual is more likely to remember a list of items when rehearsal is spaced over an extended period of time. In contrast to this is cramming which is intensive memorization in a short period of time. Also relevant is the Zeigarnik effect which states that people remember uncompleted or interrupted tasks better than completed ones. The so-called Method of loci uses spatial memory to memorize non-spatial information.[72]
Kenuvis Romero

John McAfee Teaches How To Uninstall McAfee Antivirus : videos - 0 views

  • McAfee got outed as being a poster on there.. http://www.bluelight.ru/vb/threads/541627-Hello-and-an-MDPV-Question/page11 
Kenuvis Romero

MuriGenics Inc. - 0 views

  • Passive cutaneous anaphylaxis (PCA) is an immediate dermal response to an allergen-IgE interaction and is characterized by increased permeability of vessels within the skin.
Kenuvis Romero

Snake venom - encyclopedia article - Citizendium - 0 views

  • In a case report of a human bite by a king cobra, Ophiophagus hannah, in New York City, a 30 year old reptile importer was struck by a captive in the baggage department of Kennedy Airport. "The patient instantly felt a generalized "warm rush" soon followed by euphoria, "brightly colored visual hallucinations", a distorted perception of the passage of time and "razor-like pain" throughout the right arm." (reference for quote:Warren W. Wetzel and Nicholas P. Christy: A king cobra bite in New York City • SHORT COMMUNICATION, Toxicon, Volume 27, Issue 3, (1989) Pages 393-395)
Kenuvis Romero

Tarantula - Wikipedia, the free encyclopedia - 0 views

  • accounts of bites by some species are reported to be very painful and to produce intense spasms that may recur over a period of several days; the venom by the African tarantula Pelinobius muticus also causes strong hallucinations.[13]
  • Old-world tarantulas (from Europe, Africa, Asia and Australia) have no urticating hairs and are more likely to attack when disturbed. Old-world tarantulas often have more potent, medically significant venom.
Kenuvis Romero

Dangerous: an in-depth investigation into the life of John McAfee (Wired UK) - 0 views

shared by Kenuvis Romero on 23 Jun 13 - No Cached
  •  His business plan: create an antivirus program and give it away on bulletin boards. McAfee didn't expect users to pay. His real aim was to get them to think the software was so necessary that they would install it on their computers at work. They did. Within five years, half of the Fortune 100 companies were running it, and they felt compelled to pay a licence fee. By 1990, McAfee was making $5 million (£3.2 million) a year with few overheads and little investment.
  • His success was due in part to his ability to spread his own paranoia, the fear that there was always somebody about to attack.
Kenuvis Romero

Public Photograpy Is Not a Crime - 0 views

  • it is not a criminal offence for individuals to photograph or film police officers as they go about their duties, and that police officers are not allowed to confiscate a person’s camera or recording equipment (including phones), force them to delete images, or otherwise prevent them from taking photographs or filming in public places.
  • Subject to certain very limited constraints, it is not a crime in Canada for anyone to do any of the following things, and it is a violation of their Charter rights to prevent anyone from doing so: photographing or filming in any public place, or in any private place to which the public is admitted, and publishing those pictures and films, taking pictures of or filming in any government site other than “restricted access areas”* photographing or filming police officers in public, as long as the photographer/filmmaker does not obstruct or interfere with the execution of police duties. While everyone has a reasonable expectation of privacy in certain circumstances, police officers have no reasonable expectation of privacy as they go about their duties.
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