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Completed observational study assessed whether measurements of certain pro-inflammatory and anti-inflammatory cytokines in the blood (either singly or in combination) at birth and/or up to day of life 21 can predict cerebral palsy at 18-22 months corrected age.

Observational study tests the feasibility of enrolling subjects and obtaining an amplitude-integrated electroencephalogram (aEEG) within the first 72 hours of life, a second aEEG recording between 72-168 hours of life, and weekly thereafter up to 36 weeks post-menstrual age. It will enroll 85-100 infants between 401-1,000 grams birth weight OR between 23 0/7 and 28 6/7 weeks gestational age born at the 7 participating NICHD Neonatal Research Network sites.

NICHD, NIH, Sponored and American Academy of Pediatrics, and American College of Obstetricians and Gynecologists co-sponsored study and Report of the Workship on Acute Perinatal Asphyxia in Term Infants.

PubMed absact of a retrospective review of cases, the causes of cerebral palsy in 142 children living in the northwestern United States and born after Jan 1, 1970, were prenatal in 50% of the cases, similar to findings recently reported from Sweden

Placental Abruption at Mayo Clinic - Definition - Symptoms- Information

WebMD - Cerebral Palsy - Topic Overview

Only medical center in the state that's 100% focused on caring for children, from babies to teens. Teaching hospital and home of the University of Connecticut School of Medicine Department of Pediatrics Connecticut Children's Medical Center is the largest pediatric primary care service for children between Boston and New York. Pediatricians provide primary care services such as well-child checkups and immunizations, and care for minor illnesses. Emergency room staffed serves approximately 30,000 patients annually. Surgical unit nearly 6,000 surgeries performed annually. Intensive care unit serves children with traumatic injuries, life-threatening illness and children recovering from major surgery. We're a neonatal intensive care unit caring for about 500 critically ill or premature newborn babies a year; some children who weigh one pound at birth.

NCBI NIH PubMed.gov Abstract of Finland study investigating reproductive maternal risk factors of intrapartum fetal asphyxia. The study concluded that the incidence of intrapartum fetal asphyxia was 2.5%. Placental abruption, primiparity, alcohol use during pregnancy, low birth weight, preeclampsia, male fetuses, and small-for-gestational age births were independent risk factors of intrapartum asphyxia, with adjusted relative risks of 3.74, 3.10, 1.75, 1.57, 1.49, 1.48 and 1.33, respectively. Most cases of intrapartum fetal asphyxia occur in low-risk pregnancies and, therefore, risk screening in antenatal care cannot accurately predict which women will eventually need emergency care for fetal asphyxia.

PubMed.gov 2001 Review Abstract: The outcome of extreme prematurity

2010 Ongoing study being conducted by NICHD - STAN Fetal Heart Monitor trial at clinicaltrials.gov - Research to test a new instrument, called a fetal STAN monitor, that may be used during labor to monitor the electrical activity of the baby's heart. This new instrument is designed to help the doctor determine how well the baby is doing during labor. It will be used along with the existing electronic fetal monitor used to measure the baby's heart rate and the mother's contractions during birth. The specific purpose of this research study is to see if this new instrument (fetal STAN monitor) will have an impact on newborn health.

Center is dedicated to helping people live to the fullest. Much of our work focuses on protecting people who are especially vulnerable to health risks - babies, children, people with blood disorders, and people with disabilities

NIH Medline Plus - Low Umbilical Cord pH Tied to Death, Brain Damage

For most children, a clear sign that a ventriculoperitoneal (VP) shunt is not working is a painful headache. Because Braden could not communicate his pain to me, I quickly had to learn to look for other symptoms.

Quick Reference: Fact Sheets - Umbilical Cord Abnormalities

Study to determine if Antenatal Allopurinol Administration Reduce Post-Hypoxic-Ischemic Reperfusion Damage During Fetal Hypoxia in the Newborn

Study to demonstrate beneficial effects of parenteral carnitine supplementation in premature neonates for liver, heart and muscle metabolism and functions.

In large, multicenter clinical studies, a therapy has been shown to significantly lower the risk of lung and brain damage in some very low birthweight premature infants. Results from two randomized clinical trials demonstrate that when given within the first few weeks of life, inhaled nitric oxide helps prevent chronic lung disease in some low birthweight premature infants. In addition, when used within 48 hours after birth, treatment appears to protect some premature newborns from brain injury.

NICHD National Institute of Health Eunice Kennedy Shriver National Institute of Child Health & Human Development - Center for Research for Mothers & Children CRMC - CRMC serves as a principal source of NIH support for research and research training in maternal and child health. Supported scientists are advancing fundamental and clinical knowledge concerning maternal health and child development problems, such as gestational diabetes, antecedents of adult diseases, obesity and overweight, specific learning disabilities, mechanisms of cognition and learning, growth retardation, HIV/AIDS, and other congenital infections and diseases. The Center also houses the primary federal research entity for research to understand the effects and effectiveness of pharmaceuticals on maternal and child health, as well as a large portfolio on the unique aspects of HIV/AIDS in women and mothers.

Preconception Care at Eunice Kennedy Shriver National Institute of Child Health & Human Development - What is prenatal care and preconception care?

University of California, UCSF Medical Center - Medical Tests - Fetal Heart Monitoring - Definition - Types - Information