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PubMed Abstract of double-blind study of high cervical spinal cord stimulation conducted in eight moderately disabled, spastic, cerebral palsied children failed to demonstrate any significant improvement over base line function during chronic spinal cord stimulation at either optimal stimulation parameters or random placebo parameters

Vagus Nerve Stimulation Definition at Mayo Clinic

Patients with epilepsy undergoing deep brain stimulation (DBS) have electroencephalograms (EEGs) recorded before and during their stimulation treatment. Subsequently we will be using computer-assisted analysis of the digitally-recorded EEG signals to assess the effects of DBS on the brain-wave frequency content and any abnormal seizure-like patterns that may be present.

Study being conducted to learn about the effects (both good and bad) of a brain stimulating device known as the External Responsive Neurostimulating System. This is an investigational device that was designed to detect seizure activity and give an electrical stimulation to the brain to try to stop it

PubMed Abstract of observations that concluded that significant improvements were noted when comparing the two-electrode system with the new multiple level electrode. Marked to moderately improved patients increased from 57 to 84% in Cerebral Palsy, from 44 to 82% in dystonia, from 53 to 75% in torticollis and from 53 to 80% in Cystonia, from 53 to 80% in posttraumatic neurologic conditions

Theta-burst transcranial magnetic stimulation (TBS) is a type of repetitive transcranial magnetic stimulation (rTMS) method that reduces the excitability of a small region of brain for less than one hour. Since dystonia and spasticity may be associated with increased excitability of motor cortex, we expect that by reducing the excitability of motor cortex with TBS we will temporarily improve these symptoms and hopefully open avenues in the future for the use of TBS as a new, non-invasive therapeutic intervention to aid in physical therapy and symptom amelioration of dystonia and spasticity.

FES is a form of treatment with a device to aid movement in people who have had damage to their brain or spinal cord. Small electrical impulses are used to excite and stimulate the nerves that supply paralyzed muscles. This research will look at any additional benefit that may occur when Botox injections are combined with specific occupational therapy exercises and with a device that uses functional electrical stimulation (FES) to help improve muscle function

CPI Fact Sheets providing information on research being conduct on the Use of Neuromuscular Electrical Stimulation to Increase Muscle Strength and Walking Speed in Children with Spastic Diplegic Cerebral Palsy.

This research is designed to look at any additional benefit that may occur when Botox injections are combined with specific occupational therapy exercises and with a device that uses functional electrical stimulation (FES) to help improve muscle function after stroke.

Study to determine the potential benefits of a home stimulation program to treat infants who have suffered from brain asphyxiation (lack of oxygen).

Study sponsored by NINDS to examine whether continuous use of transcranial direct current stimulation (tDCS) in combination with motor training can lead to long-term improvement in movement performance beyond what can be achieved with motor training alone.

Completed study sponsored by NINDS to determine the feasibility of using extrinsic laryngeal muscle stimulation to elevate the larynx in a manner similar to that which occurs during normal swallowing. This research will also determine whether laryngeal elevation will open the upper esophageal sphincter to assist with entry of the bolus into the esophagus. Includes studies in normal volunteers and patients with swallowing disorders.

Long-term evaluation of granulocyte-colony stimulating factor on hypoxic-ischemic brain damage in infant rats. Hypoxia-ischemia (HI), as a major cause of fetal brain damage, has long-lasting neurological implications. Therefore, therapeutic interventions that attenuate the neuropathological out come of HI while also improving the neurofunctional outcome are of paramount clinical importance. The aim of this study was to investigate the long-term functional and protective actions of granulocyte-colony stimulating factor (G-CSF) treatment in an experimental model of cerebral. RESULTS: Granulocyte-colony stimulation promoted somatic growth and prevented brain atrophy and underdevelopment of the heart in infant rats.

Completed study used transcranial magnetic stimulation (TMS) to examine how the brain controls muscle movement in dystonia. Dystonia is a movement disorder in which involuntary muscle contractions cause uncontrolled twisting and repetitive movement or abnormal postures.

Vanderbilt study is to determine the safe and effective levels of optical stimulation in peripheral nerves of humans otherwise undergoing nerve lesioning in surgery, namely children undergoing selective rhizotomy for treatment of medically refractory spasticity.

Deep Brain Stimulation: Beyond Movement Disorders By Brenda Patoine. 2010 Progress Report on Brain Research

Ivestigation is to learn whether intense swallowing exercise or intense swallowing exercise coupled with electrical stimulation (E-Stim) helps patients who had head/neck cancer and currently have dysphagia swallow better.

Provides special utensils and products for children with feeding and oral motor disorders including the Johnson Therapeutic Textured Spoon, shallow bowls and utensils that provide oral-sensory stimulation with feeding

Stanford trial assessing use of Theta-burst transcranial magnetic stimulation (TBS) as a new, non-invasive therapeutic intervention to aid in physical therapy and symptom amelioration of dystonia and spasticity

Hypertonia Information Page at National Institute of Neurological Disorders and Stroke NINDS - What is hypertonia - Treatment - Prognosis - Research - Clinical Trials and Organizations