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Pittsburgh Development Center of Magee-Womens Research Institute explores the molecular biology of cell function-- in gametes, embryos, stem cells, maternal/fetal efficacy of assisted reproduction technologies, the origins of developmental diseases, the causes and prevention of adverse pregnancy outcomes and the potential of stem cells for treating human disease

Cincinnati Children's is conducting a research project to study the white matter of the brain in children with hydrocephalus (white matter connects areas in the brain responsible for normal function). Assessments will be done through MRIs and neuropsychological tests of behavior and development.

NINDS sponsored study will examine how the areas in the brain are connected when they are controlling two finger movements at the same time. Study will examine how people use what they see to help guide two different movements. Studying will further examine the connectivity between the homologous motor areas of the two hemispheres, and between prefrontal cortex and parietal cortex, to understand sensorimotor integration processes during competitive and cooperative dual tasks.

University of California, Irvine research project to determine which combination of tests will enable physicians to predict whether a patient with symptoms of normal pressure hydrocephalus (NPH) will improve with a shunt.

Effect of treatment on the movement disorder will be measured by a myoclonus scale and a dystonia scale as well as by assessment of overall functional status. Response at various dosages will be compared to baseline for all patients.Safety parameters including neurological examination, blood tests and EKG will be monitored throughout the treatment period and during withdrawal of the medication.