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Matti Narkia

DHA reduces tumor growth - Life Extension Update - 0 views

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    Mice injected with cancer cells experienced significantly elevated levels of C-reactive protein, white blood cells, and lipid peroxidation compared with control mice. These levels were reduced in animals that received cisplatin and/or DHA. While treatment with 125 mg/kg DHA inhibited tumor growth by 38 percent compared to untreated animals, 250 mg/kg suppressed tumor growth by 79 percent, which was a greater effect than that of cisplatin alone (which was associated with a 55 percent reduction). The combination of DHA and cisplatin resulted in an 81 percent inhibition of growth, while reducing elevated white blood cell levels (leukocytosis) to normal levels. Treatment with the higher dose of DHA alone was associated with a similar reduction in white blood cells, which, when elevated, are associated with tumor growth. A strong relationship was observed between tumor growth and white blood cell levels as well as C-reactive protein levels. In another experiment with rats treated with cisplatin, the addition of 250 mg/kg DHA prevented lethal kidney toxicity in 88 percent of the animals that received it, while none of the rats that received cisplatin alone survived.
Matti Narkia

White button mushrooms appear to boost immune function - Tufts Journal: Briefs: Healthy... - 0 views

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    White button mushrooms appear to boost immune function It appears that a little fungus may be good for what ails you. That's the conclusion of a new study that found that eating white button mushrooms may boost the immune system and protect against infection. If the research, done on animals, translates to people, it could raise the health-benefit profile of the fungus, which also contains high concentrations of the super-antioxidant ergothioneine, which protects cells from damaging free radicals. "This is the first published study showing the effect of white button mushrooms on immune function," Dayong Wu, a scientist in the Immunology Laboratory at the Jean Mayer USDA Human Nutrition Research Center on Aging at Tufts and lead author of the study, published in the June issue of the Journal of Nutrition, told NutraIngredients.com. The research also suggests that the mushroom may boost both innate and acquired immune system health. The innate immune system, the one you're born with, is the body's first line of defense. The acquired immune system revs up if a pathogen makes its way past the innate system and customizes the immune response to target the invader.
Matti Narkia

Phase I Study of White Button Mushroom Extract in Preventing the Recurrence o... - 0 views

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    Phase I Study of White Button Mushroom Extract in Preventing the Recurrence of Breast Cancer in Postmenopausal Women Who Are Breast Cancer Survivors. This is a dose-escalation study. Patients receive oral white button mushroom extract twice daily for 12 weeks in the absence of a second primary ductal carcinoma in situ, invasive breast cancer, or unacceptable toxicity.ble toxicity.\n
Matti Narkia

Definition of white button mushroom extract - National Cancer Institute Drug Dictionary - 0 views

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    A heat-stable extract of white button mushrooms (Agaricus bisporus) with potential chemopreventive and immunomodulating activities. Phytochemicals, such as polysaccharides and especially beta-D-glucans found in the white button mushroom extract, bind to and inhibit the activity of aromatase, an enzyme responsible for the conversion of androgens to estrogens and which is often upregulated in breast cancer cells. The consequent decrease in estrogen production may result in the suppression of estrogen-dependent cellular proliferation. In addition, this extract may promote dendritic cell (DC) maturation, increase interferon gamma (IFN-gamma) and tumor necrosis factor alpha (TNF-alpha) production, and may enhance natural killer (NK) cell activity, thus amplifying both innate and T cell-mediated immune responses against cancer cells. Check for active clinical trials or closed clinical trials using this agent.
Matti Narkia

Wine Won't Cut Breast Cancer Risk - 0 views

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    March 9, 2009 -- Red or white wine with dinner? A new study suggests a woman's wine choice should be based on personal preference rather than any hope that a wine's color may affect its breast cancer-fighting ability. "We found no difference between red or white wine in relation to breast cancer risk. Neither appears to have any benefits," researcher Polly Newcomb, PhD, MPH, head of the Cancer Prevention Program at the Fred Hutchinson Cancer Research Center in Seattle, says in a news release.
Matti Narkia

Eating mushrooms may boost immune system (ASU Research) - 0 views

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    Edible mushrooms are a versatile functional food and have been touted as a way to preserve youth, longevity and overall health for centuries. Now nutrition researchers from Arizona State University and Pennsylvania State University are finding that they may even help boost the immune system and reduce inflammation, especially in the colon. Keith R. Martin, ASU assistant professor in nutrition, along with his Penn State colleagues, experimented with various types of mushrooms, from the more common white button to the exotic like shiitake and oyster, to see what sort of effect they had on the immune system. Their paper was published in late February in BMC Immunology, a peer reviewed online journal. "We found that the white button mushroom seemed to be the most effective in boosting the immune system, which is good because they are the most affordable," said Martin.
Matti Narkia

White button mushroom enhances maturation of bone marrow-derived dendritic cells and th... - 0 views

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    White button mushroom enhances maturation of bone marrow-derived dendritic cells and their antigen presenting function in mice.\nRen Z, Guo Z, Meydani SN, Wu D.\nJ Nutr. 2008 Mar;138(3):544-50.\nPMID: 18287364
Matti Narkia

Dietary supplementation with white button mushroom enhances natural killer cell activit... - 0 views

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    Dietary supplementation with white button mushroom enhances natural killer cell activity in C57BL/6 mice. Wu D, Pae M, Ren Z, Guo Z, Smith D, Meydani SN. J Nutr. 2007 Jun;137(6):1472-7. PMID: 17513409
Matti Narkia

White button mushroom (Agaricus bisporus) exhibits...[Nutr Cancer. 2008] - PubMed Result - 0 views

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    White button mushroom (Agaricus bisporus) exhibits antiproliferative and proapoptotic properties and inhibits prostate tumor growth in athymic mice. Adams LS, Phung S, Wu X, Ki L, Chen S. Nutr Cancer. 2008;60(6):744-56. PMID: 19005974
Matti Narkia

White button mushroom phytochemicals inhibit aromatase activity and breast cancer cell ... - 0 views

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    White button mushroom phytochemicals inhibit aromatase activity and breast cancer cell proliferation. Grube BJ, Eng ET, Kao YC, Kwon A, Chen S. J Nutr. 2001 Dec;131(12):3288-93. PMID: 11739882
Matti Narkia

Anti-aromatase activity of phytochemicals in white button mushrooms (Agaricus bisporus)... - 0 views

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    Anti-aromatase activity of phytochemicals in white button mushrooms (Agaricus bisporus). Chen S, Oh SR, Phung S, Hur G, Ye JJ, Kwok SL, Shrode GE, Belury M, Adams LS, Williams D. Cancer Res. 2006 Dec 15;66(24):12026-34. PMID: 17178902 doi: 10.1158/0008-5472.CAN-06-2206
Matti Narkia

White button mushroom (Agaricus bisporus) exhibits antiproliferative and proapoptotic p... - 0 views

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    White button mushroom (Agaricus bisporus) exhibits antiproliferative and proapoptotic properties and inhibits prostate tumor growth in athymic mice. Adams LS, Phung S, Wu X, Ki L, Chen S. Nutr Cancer. 2008;60(6):744-56. PMID: 19005974
Matti Narkia

White Button Mushroom (Agaricus Bisporus) Exhibits Antiproliferative and Proapoptotic P... - 0 views

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    White button mushroom (Agaricus bisporus) exhibits antiproliferative and proapoptotic properties and inhibits prostate tumor growth in athymic mice. Adams LS, Phung S, Wu X, Ki L, Chen S. Nutr Cancer. 2008;60(6):744-56. PMID: 19005974 DOI: 10.1080/01635580802192866
Matti Narkia

Newsmax.com - Mushrooms Could Strengthen Immunity - 0 views

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    Mushrooms could give the immune system a hand in attacking foreign invaders, if the effects in mice translate to humans.\n\nWhat's more, the common white button mushroom had stronger immune-boosting effects than more exotic -- and more expensive -- fungi such as oyster and shiitake mushrooms, Dr. Keith Martin of Arizona State University in Mesa and his colleagues found
Matti Narkia

Pharma DCA - The Purest 99+% Pure and Lowest Price Pharmaceutical Grade DCA in the Worl... - 1 views

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    Welcome to Pharma-DCA.com the number 1 source to buy pharmaceutical quality DCA sodium dichloroacetate made only from pure crystal clear 99+% dichloroacetic acid There are no organic solvents used in making Pharma-DCA.com sodium dichloroacetate which comes as an excellent dry white powder.
Matti Narkia

Berberine, dosing and safety - wellness.com - 0 views

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    Side Effects and Warnings Berberine has been reported to cause nausea, vomiting, hypertension (high blood pressure), respiratory failure and paresthesias (abnormal sensations such as numbness or tingling); however, clinical evidence of such adverse effects is not prominent in the literature. Rare adverse effects including headache, skin irritation, facial flushing, headache, bradycardia (slowed heart rate) have also been reported with the use of berberine. Use cautiously when taking berberine for longer than eight weeks due to theoretical changes in bacterial gut flora. Use cautiously in individuals with diabetes, as both human and animal studies indicate that berberine may decrease blood sugar levels. Also use cautiously in individuals with hypotension (low blood pressure), as berberine may have antihypertensive effects. Patients with cardiovascular disease should also use caution as berberine has been associated with the development of ventricular arrhythmias in subjects with congestive heart failure. Although not well studied in humans, berberine may also theoretically cause delays in small intestinal transit time or increase the risk of bleeding. Berberine may cause abortion, eye or kidney irritation, nephritis (inflamed kidneys), dyspnea (difficulty breathing), flu-like symptoms, giddiness, lethargy, or liver toxicity. Patients with leukopenia (abnormally low white blood cell count) should use cautiously due to the potential for development of leukopenia symptoms. When injected under the skin, berberine may cause hyperpigmentation in the arm. Use berberine cautiously in individuals with high exposure to sunlight or artificial light due to potential for adverse phototoxic reactions. Avoid in newborns due to potential for increase in free bilirubin, jaundice, and development of kernicterus (brain damage caused by severe newborn jaundice). Use berberine cautiously in children due to a lack of safety information. Pregnancy and Breastfeeding Berberine is not recomme
fifthseason financial

Loans for terminally ill - 0 views

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    Fifth Season provides loans for late-stage cancer patients, secured by their existing life insurance policy. Apply now for a cancer loan or financial support at Fifth Season Financial.
Matti Narkia

The effects of whole mushrooms during inflammation. - BioMed Central | Full text | - 0 views

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    The effects of whole mushrooms during inflammation.\nYu S, Weaver V, Martin K, Cantorna MT.\nBMC Immunol. 2009 Feb 20;10:12.\nPMID: 19232107 \ndoi:10.1186/1471-2172-10-12\n
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